BRUNO DA COSTA MARTINS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
10 resultados
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- EUS-guided gastroenterostomy: Initial experience in a brazilian tertiary center(2020) OLIVEIRA, Joel Fernandez de; CORDERO, Martin Andres Coronel; LIMA, Gustavo Rosa de Almeida; PAULO, Gustavo Andrade de; LIMA, Marcelo Simas de; MARTINS, Bruno da Costa; JR, Ulysses Ribeiro; MALUF-FILHO, FauzeINTRODUCTION: EUS-guided gastroenterostomy (EUS-GE) is a novel procedure for palliation of malignant gastric outlet obstruction (GOO). Our aim was to evaluate the outcomes of this technique in our initial experience. METHODS: Patients with GOO from our institute were included. Technical success was defined as the successful creation of a gastroenterostomy. Clinical success was defined as the ability to tolerate a soft diet after the procedure. We assessed adverse events and diet tolerance 1 month after the procedure. RESULTS: Three patients were included. Technical and clinical success was achieved in all cases. There were no adverse events and good diet tolerance was observed 1 month after the procedure in the included patients. CONCLUSION: EUS-GE is a promising treatment for patients with GOO.
bookPart Banda Gástrica | Migração e Deslizamento(2020) DOMINGUES, Thiago Alonso; MARTINS, Bruno da Costaarticle Pancreatic Metastasis from Papillary Thyroid Carcinoma: A Case Report(2020) MACHADO, Andressa A.; LENZ, Luciano; DOMINGUES, Regina B.; LIMA, Gustavo R. A.; JOSINO, Iatagan R.; CORDERO, Martin A. C.; V, Adriana Safatle-Ribeiro; MARTINS, Bruno C.; PENNACCHI, Caterina M. P. S.; GUSMON, Carla C.; PAULO, Gustavo A.; LIMA, Marcelo S.; BABA, Elisa R.; KAWAGUTI, Fabio S.; UEMURA, Ricardo S.; MALUF-FILHO, FauzeIntroduction differentiated thyroid carcinoma presents with distant metastasis in 4% of cases, usually occurring in the lungs, bones and thoracic lymph nodes. Pancreatic involvement is extremely rare, with few cases reported in the literature. Case report A 47-years-old female patient presented abdominal pain. She had a history of papillary thyroid carcinoma surgically resected in 2009. After 10 years, computed tomography revealed hepatic lesions suggestive of secondary involvement and a solid mass in the pancreatic head. Endoscopic ultrasound fine-needle aspiration was performed in a heterogeneous hypoechoic mass located at pancreatic head. Cell block with immunohistochemistry was positive for thyroglobulin, suggesting papillary thyroid carcinoma metastasis. The patient still survives at present, treating metastasis with Cabozantinib. Conclusion endoscopic ultrasound fine-needle aspiration is a minimally invasive and accurate method of sampling lesions of the pancreas. In combination with clinical history and immunohistochemistry, can confirm diagnosis and define management.conferenceObject IMPACT OF RADIOTHERAPY (RT) ON ADVERSE EVENTS OF SELF-EXPANDING METALLIC STENTS (SEMS) IN PATIENTS WITH ESOPHAGEAL CANCER(2020) MACHADO, Andressa A.; MARTINS, Bruno da Costa; LIMA, Gustavo R.; JOSINO, Iatagan; CORONEL, Martin A.; LIMA, Marcelo S. de; SAFATLE-RIBEIRO, Adriana V.; PENNACCHI, Caterina; GUSMON, Carla C.; BABA, Elisa; KAWAGUTI, Fabio S.; LENZ, Luciano H.; UEMURA, Ricardo S.; PAULO, Gustavo A. de; GEIGER, Sebastian N.; SALLUM, Rubens A.; RIBEIRO, Ulysses; MALUF-FILHO, FauzeconferenceObject ESOPHAGORESPIRATORY FISTULAS INDUCED BY SEMS IN THE TREATMENT OF MALIGNANT ESOPHAGEAL STRICTURES(2020) JOSINO, Iatagan R.; MACHADO, Andressa A.; LIMA, Gustavo R.; CORONEL, Martin A.; LIMA, Marcelo S. de; KAWAGUTI, Fabio S.; GUSMON, Carla C.; UEMURA, Ricardo S.; PENNACCHI, Caterina; LENZ, Luciano; SAFATLE-RIBEIRO, Adriana V.; BABA, Elisa; GEIGER, Sebastian N.; PAULO, Gustavo A. de; MARTINS, Bruno da Costa; MALUF-FILHO, Fauze- Long-term survival analysis after endoscopic stenting as a bridge to surgery for malignant colorectal obstruction: comparison with emergency diverting colostomy(2020) SCOMPARIN, Rodrigo Corsato; MARTINS, Bruno Costa; LENZ, Luciano; BENTO, Luiza Haendchen; MARQUES, Carlos Sparapam; SAFATLE-RIBEIRO, Adriana; JR, Ulysses Ribeiro; NAHAS, Sergio Carlos; MALUF-FILHO, FauzeThe use of colorectal self-expanding metal stents (SEMS) as bridge therapy for malignant colorectal obstruction was first reported more than 20 years ago. However, its use remains controversial. OBJECTIVE: In this study, we aimed to compare the long-term survival of patients with potentially resectable malignant colorectal obstruction who had undergone colorectal SEMS placement and emergency surgery. METHODS: This study was a retrospective analyses. Patients who received treatment between 2009 and 2017 were included. According to the eligibility criteria, 21 patients were included in the SEMS group and 67 patients were included in the surgical group. RESULTS: The majority of the patients in the SEMS group were female (57.1%), whereas the majority of those in the surgical group were male (53.7%). The median follow-up time was 60 months for both groups with the same interquartile range of 60 months. There was no difference in the overall survival rate (log rank p=0.873) and disease-free survival rate (log rank p=0.2821) in the five-year analysis. There was no difference in local recurrence rates (38.1% vs. 22.4%, p=0.14) or distant recurrence rates (33.3% vs. 50.7%, p=0.16) in the SEMS and the surgical groups. Technical and clinical success rates of endoscopic stenting were 95.3% and 85.7%, respectively. There were no immediate adverse events (AEs). Severe AEs included perforation (14.3%), silent perforation (4.7%), reobstruction (14.3%), and bleeding (14.3%). Mild AEs included pain (42.8%), tenesmus (9.5%), and incontinence (4.76%). The limitations of this study was retrospective and was conducted at a single center. CONCLUSIONS: No differences in disease-free and overall survival rates were observed in the five-year analysis of patients with resectable colorectal cancer who had undergone SEMS placement or colostomy for the treatment of malignant colorectal obstruction. Patients in the SEMS group had a higher rate of primary anastomosis and a lower rate of temporary colostomy than did those in the surgery group.
- Impact of coronavirus pandemic crisis in endoscopic clinical practice: Results from a national survey in Brazil(2020) ARANTES, Vitor Nunes; MARTINS, Bruno Costa; SEQATTO, Raphael; MILHOMEN-CARDOSO, Daniela Medeiros; FRANZINI, Tomazo Prince; ZUCCARO, Anna Maria; ALVES, Jairo Silva; MALUF-FILHO, FauzeBackground and study aims In March 2020, the World Health Organization declared coronavirus disease of 2019 (COVID-19) as a pandemic, mobilizing all countries to contain the disease spread. Activity in endoscopy centers globally was severely affected. We conducted a national survey aiming to assess the impact of the COVID-19 outbreak on endoscopic clinical practice in Brazil. Methods In April 2020, 3,719 associate members of SOBED (Brazilian Society of Digestive Endoscopy) were invited to respond to an electronic survey. An Internet link was established to provide access to the online questionnaire with 40 questions regarding personal profile, endoscopy unit logistics and schedule, availability and use of personal protective equipment (PPE), financial impact, and exposure to COVID-19. Results A total of 2,131 individuals (67 %) accessed the questionnaire and 1155 responses were received. After review, 980 responses were considered valid. According to almost 90 % of respondents, endoscopy activity was restricted to urgent procedures, in both public and private hospitals. All respondents increased PPE use after the outbreak, however, institutions provided adequate PPE to only 278 responders (28.7 %). Significant income loss was universally reported. A total of 10 practitioners (1 %) reported COVID-19 infection and attributed the contamination to endoscopic procedures. Conclusions Based on this nationwide survey with almost 1,000 respondents, the COVID-19 pandemic substantially reduced the activity of endoscopy units in private and public settings. The pandemic increased awareness of PPE use, but its availability was not universal and 1 % of the respondents became infected with COVID-19, allegedly due to exposure during endoscopic procedures.
- UNDERWATER ENDOSCOPIC MUCOSAL RESECTION FOR NON-PEDUNCULATED COLORECTAL LESIONS. A PROSPECTIVE SINGLE-ARM STUDY(2020) LENZ, Luciano; MARTINS, Bruno; KAWAGUTI, Fabio Shiguehisa; TELLIAN, Alexandre; PENNACHI, Caterina Maria Pia Simoni; SORBELLO, Mauricio; GUSMON, Carla; PAULO, Gustavo Andrade de; UEMURA, Ricardo; GEIGER, Sebastian; LIMA, Marcelo Simas de; SAFATLE-RIBEIRO, Adriana; BABA, Elisa; HASHIMOTO, Claudio Lyoiti; MALUF-FILHO, Fauze; RIBEIRO JR, UlyssesABSTRACT BACKGROUND: Underwater endoscopic mucosal resection (UEMR) has emerged as a revolutionary method allowing resection of colorectal lesions without submucosal injection. Brazilian literature about this technique is sparse. OBJECTIVE: The aim of this study was evaluate the efficacy and safety of UEMR technique for removing non-pedunculated colorectal lesions in two Brazilian tertiary centers. METHODS: This prospective study was conducted between June 2016 and May 2017. Naïve and non-pedunculated lesions without signs of submucosal invasion were resected using UEMR technique. RESULTS: A total of 55 patients with 65 lesions were included. All lesions, except one, were successfully and completely removed by UEMR (success rate 98.5%). During UEMR, two cases of bleeding were observed (3.0%). One patient had abdominal pain on the day after resection without pneumoperitoneum. There was no perforation or delayed bleeding. CONCLUSION: This study supports the existing data indicating acceptable rates of technical success, and low incidence of adverse events with UEMR. The results of this Brazilian study were consistent with previous abroad studies.
conferenceObject COMPARISON OF COVERED VS. UNCOVERED SELF-EXPANDABLE METAL STENTS FOR PALLIATION OF DISTAL MALIGNANT BILIARY STRICTURES(2020) LIMA, Gustavo R.; MARTINS, Bruno da Costa; CORONEL, Martin A.; JOSINO, Iatagan R.; MACHADO, Andressa A.; KAWAGUTI, Fabio S.; LIMA, Marcelo S. de; PENNACCHI, Caterina; LENZ, Luciano H.; UEMURA, Ricardo S.; PAULO, Gustavo A. de; GUSMON, Carla C.; BABA, Elisa; GEIGER, Sebastian N.; RIBEIRO, Ulysses; SAFATLE-RIBEIRO, Adriana V.; MALUF-FILHO, FauzeconferenceObject DIAGNOSTIC EVALUATION OF CLINICAL COMPLETE RESPONSE BY PROBE-BASED CONFOCAL ENDOMICROSCOPY AFTER NEOADJUVANT CHEMORADIATION FOR LOCALLY ADVANCED RECTAL ADENOCARCINOMA(2020) SAFATLE-RIBEIRO, Adriana V.; MARQUES, Carlos F.; PIRES, Clelma Batista; ARRAES, Livia; MEIRELLES, Luciana; BABA, Elisa R.; MACHADO, Andressa A.; CORONEL, Martin A.; LIMA, Gustavo R.; JOSINO, Iatagan; ARAUJO, Diogo; PELEGRINELLI-ZAIDAN, Evelise; GUSMON, Carla C.; LIMA, Marcelo S. de; PENNACCHI, Caterina; KAWAGUTI, Fabio S.; UEMURA, Ricardo S.; MARTINS, Bruno da Costa; PAULO, Gustavo A. de; LENZ, Luciano; COTTI, Guilherme C.; NAHAS, Caio Sergio R.; NAHAS, Sergio C.; RIBEIRO, Ulysses; MALUF-FILHO, Fauze