ROBERTO FALZONI

Índice h a partir de 2011
4
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico

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  • article 1 Citação(ões) na Scopus
    Low-grade fibromyxoid sarcoma in labial mucosa: Report of a rare case in a pediatric patient
    (2022) PENAFORT, Paulo Victor Mendes; PAGLIONI, Mariana de Pauli; SIQUEIRA, Sheila Aparecida Coelho; FALZONI, Roberto; MENDONCA, Regina Maria Holanda de; LOPES, Marcio Ajudarte; VARGAS, Pablo Agustin; SANTOS-SILVA, Alan Roger
    Low-grade fibromyxoid sarcoma (LGFMS) is a malignant neoplasm of soft tissue, which occurs mainly in ex-tremities. In this study, we described a rare case of LGFMS arising in the labial mucosa, in a 7-year-old male patient, who presented a painless multilobulated growth with an evolution time of 12 months. An incisional biopsy was performed and microscopic examination revealed a proliferation of bland regular spindle cells in an alternating myxoid and hyalinized stroma. The tumor cells showed a strong cytoplasmic immunoreactivity for MUC4 and low cell proliferation index measured by Ki-67 antibody. The diagnosis of LGFMS was established and the patient was referred for surgical treatment at a pediatric oncology hospital.
  • article 8 Citação(ões) na Scopus
    Management of desmoid-type fibromatosis involving peripheral nerves
    (2012) SIQUEIRA, Mario G.; TAVARES, Paulo L.; MARTINS, Roberto S.; HEISE, Carlos O.; FORONI, Luciano H. L.; BORDALO, Marcelo; FALZONI, Roberto
    Desmoid-type fibromatosis is an uncommon and aggressive neoplasia, associated with a high rate of recurrence. It is characterized by an infiltrative but benign fibroblastic proliferation occurring within the deep soft tissues. There is no consensus about the treatment of those tumors. We present a surgical series of four cases, involving the brachial plexus (two cases), the median nerve and the medial brachial cutaneous nerve. Except for the last case, they were submitted to multiple surgical procedures and showed repeated recurrences. The diagnosis, the different ways of treatment and the prognosis of these tumoral lesions are discussed. Our results support the indication of radical surgery followed by radiotherapy as probably one of the best ways to treat those controversial lesions.