LUIZ VICENTE RIBEIRO FERREIRA DA SILVA FILHO
Projetos de Pesquisa
Unidades Organizacionais
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
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bookPart Crise asmática(2023) SEVERINI, Rafael da Silva Giannasi; SILVA FILHO, Luiz Vicente Ribeiro Ferreira dabookPart Teste do suor e outros recursos diagnósticos para a fibrose cística(2023) ADDE, Fabíola Villac; SILVA FILHO, Luiz Vicente Ribeiro Ferreira daconferenceObject The Impact of Neonatal Screening on the Pulmonary Function of School-aged Children with Cystic Fibrosis(2023) MUNOZ, T. A. Soria; AMORAS, A. Da Silva; SARUHASHI, R. Porto Avary de Campos; SILVA, R. Galdino Da; GOMES, I. M. Forti; PEREIRA, C. M. Lourinho; ARANHA NETTO, N.; TANAKA, S. Onoda Tomikawa; NAKAIE, C. M. Aversa; RODRIGUES, J. C.; V, L. Ribeiro Ferreira Silva FilhoconferenceObject Chest Computed Tomography for Infants and Preschoolers with Cystic Fibrosis: When to Indicate and What are the Therapeutic Implications?(2023) AMORAS, A. Da Silva; MUNOZ, T. A. Soria; SILVA, R. Galdino Da; CAMPOS, R. Porto Avary de; GOMES, I. M. Forti; PEREIRA, C. M. Lourinho; ARANHA NETTO, N.; TANAKA, S. Onoda Tomikawa; NAKAIE, C. M. Versa; RODRIGUES, J. C.; SILVA FILHO, L. V. Ribeiro Ferreira Da- Five-year performance analysis of a cystic fibrosis newborn screening program in northeastern Brazil(2023) GODOY, Carolina; PAIXAO, Danielle C.; BOA-SORTE, Ney C. A.; AMORIM, Tatiana; SILVA FILHO, Luiz Vicente R. F. da; SOUZA, Edna LuciaObjective: To analyze the performance of the cystic fibrosis (CF) newborn screening (NBS) pro-gram over its first five years in a Brazilian northeastern state. Method: A population-based study using a screening algorithm based on immunoreactive tryp-sinogen (IRT)/IRT. Data were retrieved from the state referral screening center registry. The pro-gram performance was evaluated using descriptive indicators such as the results of an active search, coverage, newborn's age at the time of blood sampling, the time between sample collec-tion and its arrival at the laboratory, and the child's age at diagnosis of disease. Results: The public CF screening program covered 82.6% of the 1,017,576 births that occurred, with an accumulated five-year incidence of 1:20,767 live births. The median (25th-75th) age at diagnosis was 3.5 (2.3-7.3) months. The sampling before 7 days of life for the first IRT (IRT1) increased between 2013 and 2017 from 42.2 to 48.3%. Around 5% of IRT1 samples and 30% of the second samples were collected after 30 days of life. In the first and second stages of screening, 23.6% and 19.9% of the infants, respectively, were lost to follow-up. In both stages of screening, the samples were retained at the health units for a median (25th -75th) of 9.0 (7.0-13.0) days. Conclusions: The coverage by the CF-NBS program was satisfactory as compared to other Brazil-ian state rates and the percentage of IRT1 samples collected within the first week of life increased progressively. However, time of samples retention at the health units, inappropriate sampling, inherent methodological problems, and loss of follow-up need to improve.(c) 2022 Sociedade Brasileira de Pediatria.