LUIZ VICENTE RIBEIRO FERREIRA DA SILVA FILHO
Projetos de Pesquisa
Unidades Organizacionais
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject MARKED CFTR GENOTYPING DIFFERENCES BETWEEN BRAZILIAN REGIONS(2018) SILVA FILHO, L. R.; REIS, F. C.; MAROSTICA, P.; ATHANAZIO, R. A.; DAMACENO, N.; PAES, A. T.; HIRA, A. Y.conferenceObject Early CF Lung Disease: The Brazilian Experience(2017) SILVA FILHO, Luiz Vicente Ribeiro F. daconferenceObject A NEW INSIGHT ON CFTR ALLELE FREQUENCY IN BRAZIL THROUGH NEXT GENERATION SEQUENCING(2016) NUNES, Luisa Mesquita; RIBEIRO, Roberto; SABINO, Ester; NIEWIANDONSKI, Vivian D. T.; YAMAMOTO, Guilherme Lopes; SILVA FILHO, Luiz Vicente Ribeiro F. daconferenceObject ALBUTEROL VIA METERED-DOSE INHALER FOR ACUTE ASTHMA IN CHILDREN: LOWER DOSES ARE SUFFICIENT AND HIGHER DOSES ARE SAFE(2015) MUCHAO, F. P.; SOUZA, J. M.; TORRES, H. C.; LALIBERA, I. B.; SCHVARTSMAN, C.; RODRIGUES, J. C.; V, L. Silva FilhoconferenceObject A MILD PANCREATIC SUFFICIENT CF-PHENOTYPE ON TWO UNRELATED PATIENTS WITH THE I148N;5T MUTATION(2016) NUNES, Luisa Mesquita; NIEWIANDONSKI, Vivian D. T.; GABURO, Nelson; YAMAMOTO, Guilherme Lopes; BERTOLA, Debora Romeu; SILVA FILHO, Luiz Vicente Ribeiro F. daconferenceObject NEBULIZER SYSTEMS USED BY CYSTIC FIBROSIS PATIENTS FROM MINAS GERAIS (BRAZIL): ARE THEY WORKING PROPERLY?(2016) AQUINO, Evanirso da Silva; VERGARA, Alberto Andrade; SANTANA, Gustavo; SILVA, Luiz Vicente R. Ferreira da- Albuterol via metered-dose inhaler in children: Lower doses are effective, and higher doses are safe(2016) MUCHAO, Fabio Pereira; SOUZA, Juliana Miguita e; TORRES, Helida Conceicao Cavalcante; LALIBERA, Isabella Batista De; SOUZA, Andrea Vieira de; RODRIGUES, Joaquim Carlos; SCHVARTSMAN, Claudio; SILVA FILHO, Luiz Vicente Ribeiro Ferreira daBackgroundThe ideal dosing of albuterol via metered-dose inhalers for acute childhood asthma is not well established. We hypothesized that greater doses of albuterol would result in less time in the hospital and lower admission rates. MethodsThis was a randomized controlled double-blind multicenter study, conducted in emergency rooms (ER). We included patients with 2-17 years old with moderate to severe acute asthma (Pediatric Respiratory Assessment Measure, PRAM, score 5). Dosages administered during the first hour included: 6 (up to 25kg) or 12 puffs (>25kg) in the control group and 9 (up to 15kg), 12 (>15-20kg), 15 (>20-25kg), or 18 puffs (>25kg) in the study group. Several efficacy (changes in PRAM score, pulse oximetry, and FEV1, length of stay, and admission rates) and safety (albuterol plasma levels, heart rate, serum potassium, glucose and bicarbonate levels, EKG, and tremor rates) outcome measures were assessed. ResultsWe included 119 patients with similar baseline conditions, and no significant differences were observed between groups in the length of stay (P=0.48) or admission rate (P=0.55). No significant differences were observed in FEV1, PRAM score, and pulse oximetry changes after 1hr and at discharge or admission. No significant differences were observed in safety outcomes between groups. ConclusionsHigher albuterol dosage regimens did not result in lower admission rate or shorter length of stay in the ER, but showed similar safety profile for children with moderate to severe acute asthma. Pediatr Pulmonol. 2016;51:1122-1130. (c) 2016 Wiley Periodicals, Inc.
conferenceObject The Impact of Neonatal Screening on the Pulmonary Function of School-aged Children with Cystic Fibrosis(2023) MUNOZ, T. A. Soria; AMORAS, A. Da Silva; SARUHASHI, R. Porto Avary de Campos; SILVA, R. Galdino Da; GOMES, I. M. Forti; PEREIRA, C. M. Lourinho; ARANHA NETTO, N.; TANAKA, S. Onoda Tomikawa; NAKAIE, C. M. Aversa; RODRIGUES, J. C.; V, L. Ribeiro Ferreira Silva FilhoconferenceObject NEXT GENERATION SEQUENCING OF CFTR IN BRAZILIAN CF CHILDREN(2015) NUNES, L. M.; RIBEIRO, R.; NIEWIADONSKI, V. D.; NISHIMURA, P. Y.; SABINO, E.; SILVA FILHO, L. R. daconferenceObject Cystic Fibrosis Carriership and Tuberculosis: Hints toward an Evolutionary Selective Advantage Based on Data from the Brazilian Territory.(2017) BOSCH, L.; BOSCH, B.; BOECK, K. De; NAWROT, T.; MEYTS, I; VANNESTE, D.; BOURLEGAT, C. Alexandre Le; CRODA, J.; SILVA FILHO, Ribeiro Ferreira da