GALILEU FERREIRA AYALA FARIAS

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  • conferenceObject
    ENDOSCOPIC ULTRASOUND FINE NEEDLE ASPIRATION VERSUS FINE NEEDLE BIOPSY FOR LYMPH NODE DIAGNOSIS: A COMPARATIVE ANALYSIS
    (2019) MOURA, Diogo T. de; FARIAS, Galileu F.; JIRAPINYO, Pichamol; HOLZWANGER, Erik A.; BAZARBASHI, Ahmad Najdat; ZHAI, Yaqi; RYOU, Marvin; THOMPSON, Christopher C.
  • conferenceObject
    PREDICTORS OF GASTROESOPHAGEAL REFLUX AFTER POEM FOR ACHALASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2019) MOTA, Raquel Cristina L.; MOURA, Eduardo G. de; MOURA, Diogo T. de; MOURA, Eduardo T.; FARIAS, Galileu F.; BRUNALDI, Vitor O.; BERNARDO, Wanderlei M.; SAKAI, Paulo; THOMPSON, Christopher C.
  • article 28 Citação(ões) na Scopus
    Endoscopic vacuum therapy versus endoscopic stenting for upper gastrointestinal transmural defects: Systematic review and meta-analysis
    (2021) MONTE JUNIOR, Epifanio Silvino do; MOURA, Diogo Turiani Hourneaux de; RIBEIRO, Igor Braga; HATHORN, Kelly Elizabeth; FARIAS, Galileu Ferreira Ayala; TURIANI, Carolina Vaz; MEDEIROS, Flaubert Sena; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux de
    Background: Upper gastrointestinal fistulas, leaks, and perforations represent a high cost burden to health systems worldwide, with high morbidity and mortality rates for affected patients. Management of these transmural defects remains therapeutically challenging. Objectives: The aim of this study is to perform a systematic review and meta-analysis to investigate the efficacy and safety of self-expanding metal stents (SEMS) versus endoscopic vacuum therapy (EVT) for treatment of upper gastrointestinal transmural defects. Methods: Searches were performed on MEDLINE, EMBASE, Central Cochrane, Latin American and Caribbean Health (LILACS), and gray literature, as well as a manual search to identify studies comparing SEMS versus EVT to treat upper gastrointestinal transmural defects. Evaluated outcomes were: rates of successful closure, mortality, length of hospital stay, duration of treatment, and adverse events. Results: Five studies with a total of 274 patients were included. There was a 21% increase in successful fistula closure attributed to EVT compared with the SEMS group (RD 0.21, CI 0.10-0.32; P = 0.0003). EVT demonstrated a 12% reduction in mortality compared to stenting (RD 0.12, CI 0.03-0.21; P = 0.006) and an average reduction of 14.22 days in duration of treatment (CI 8.38-20.07; P < 0.00001). There was a 24% reduction in adverse events (RD 0.24, CI 0.13-0.35; P = 0.0001. There were no statistical differences between the studied therapies regarding the length of hospital stay. Conclusion: Endoscopic vacuum therapy proves to be superior in successful defect closure, mortality, adverse events and duration of treatment.
  • conferenceObject
    ENDOSCOPIC FINDINGS IN SEVERE YELLOW FEVER PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL BLEEDING: A RETROSPECTIVE CASE SERIES STUDY
    (2019) GALETTI, Facundo; FARIAS, Galileu F.; MARTINS, Rafael K.; CORONEL, Martin A.; REZENDE, Daniel T.; ROCHA, Rodrigo S.; MOURA, Diogo T. de; BRUNALDI, Vitor O.; HO, Yeh-Li; BABA, Elisa; MOURA, Eduardo G. de
  • article 3 Citação(ões) na Scopus
    Peroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication for esophageal achalasia: A single-center randomized controlled trial
    (2022) MOURA, Eduardo Turiani Hourneaux de; JUKEMURA, Jose; RIBEIRO, Igor Braga; FARIAS, Galileu Ferreira Ayala; DELGADO, Aureo Augusto de Almeida; COUTINHO, Lara Meireles Azeredo; MOURA, Diogo Turiani Hourneaux de; SALLUM, Rubens Antonio Aissar; NASI, Ary; SANCHEZ-LUNA, Sergio A.; SAKAI, Paulo; MOURA, Eduardo Guimaraes Hourneaux de
    BACKGROUND Achalasia is a rare benign esophageal motor disorder characterized by incomplete relaxation of the lower esophageal sphincter (LES). The treatment of achalasia is not curative, but rather is aimed at reducing LES pressure. In patients who have failed noninvasive therapy, surgery should be considered. Myotomy with partial fundoplication has been considered the first-line treatment for non-advanced achalasia. Recently, peroral endoscopic myotomy (POEM), a technique that employs the principles of submucosal endoscopy to perform the equivalent of a surgical myotomy, has emerged as a promising minimally invasive technique for the management of this condition. AIM To compare POEM and laparoscopic myotomy and partial fundoplication (LM-PF) regarding their efficacy and outcomes for the treatment of achalasia. METHODS Forty treatment-naive adult patients who had been diagnosed with achalasia based on clinical and manometric criteria (dysphagia score >= II and Eckardt score > 3) were randomized to undergo either LM-PF or POEM. The outcome measures were anesthesia time, procedure time, symptom improvement, reflux esophagitis (as determined with the Gastroesophageal Reflux Disease Questionnaire), barium column height at 1 and 5 min (on a barium esophagogram), pressure at the LES, the occurrence of adverse events (AEs), length of stay (LOS), and quality of life (QoL). RESULTS There were no statistically significant differences between the LM-PF and POEM groups regarding symptom improvement at 1, 6, and 12 mo of follow-up (P = 0.192, P = 0.242, and P = 0.242, respectively). However, the rates of reflux esophagitis at 1, 6, and 12 mo of follow-up were significantly higher in the POEM group (P = 0.014, P < 0.001, and P = 0.002, respectively). There were also no statistical differences regarding the manometry values, the occurrence of AEs, or LOS. Anesthesia time and procedure time were significantly shorter in the POEM group than in the LM-PF group (185.00 +/- 56.89 and 95.70 +/- 30.47 min vs 296.75 +/- 56.13 and 218.75 +/- 50.88 min, respectively; P = 0.001 for both). In the POEM group, there were improvements in all domains of the QoL questionnaire, whereas there were improvements in only three domains in the LM-PF group. CONCLUSION POEM and LM-PF appear to be equally effective in controlling the symptoms of achalasia, shortening LOS, and minimizing AEs. Nevertheless, POEM has the advantage of improving all domains of QoL, and shortening anesthesia and procedure times but with a significantly higher rate of gastroesophageal reflux
  • conferenceObject
    SURGICAL VS. ENDOSCOPIC TREATMENT FOR PANCREATIC PSEUDOCYSTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2018) FARIAS, Galileu F.; VISCONTI, Thiago A.; GONCALVES, Caio V. Tranquillini; GUEDES, Hugo G.; MARTINS, Rafael K.; MOURA, Eduardo T.; MATUGUMA, Sergio E.; SANTOS, Marcos E. dos; SOUZA, Thiago F.; MOURA, Eduardo G. de
  • conferenceObject
    HOW DOES PER ORAL ENDOSCOPIC MYOTOMY COMPARE TO HELLER MYOTOMY IN CHAGAS PATIENTS: THE LATIN AMERICAN SHIFT
    (2018) KAHALEH, Michel; TYBERG, Amy; SURESH, Supriya; LAMBROZA, Arnon; GAIDHANE, Monica; ZAMARRIPA, Felipe; MARTINEZ, Ma Guadalupe; CARAMES, Juan C.; MOURA, Eduardo T.; FARIAS, Galileu F.; MONDRAGON, Oscar V. Hernandez; PORFILIO, Maria G.; NIETO, Jose; REY, Mario; CASASRODRIGUEZ, Fernando; CASTILLO, Bismarck; LUKASHOK, Hannah P.; ROBLES-MEDRANDA, Carlos; MOURA, Eduardo G. de
  • article 17 Citação(ões) na Scopus
    Argon plasma coatmlation alone versus argon plasma coagulation plus full-thickness endoscopic suturing to treat weight regain after Roux-en-Y gastric bypass: a prospective randomized trial (with videos)
    (2020) BRUNALDI, Vitor Ottoboni; FARIAS, Galileu Ferreira Ayala; REZENDE, Daniel Tavares de; CAIRO-NUNES, Gabriel; RICCIOPPO, Daniel; MOURA, Diogo Turiani Hourneaux de; SANTO, Marco Aurelio; MOURA, Eduardo Guimaraes Hourneaux de
    Background and Aims: A significant number of patients regain weight after Roux-en-Y gastric bypass. Ablation with argon plasma coagulation (APC) plus endoscopic full-thickness suturing (FTS-APC) and ablation alone have been reported for treating weight regain when associated with gastrojejunostomy (GJ) dilation. However, comparative controlled data are still lacking. Methods: This was a pilot single-center open-label randomized trial comparing the effectiveness and safety of APC alone versus FTS-APC for transoral outlet reduction. Patients with at least 20% weight regain from the nadir, and GJ >= 15 mm were considered eligible. The primary outcome was percentage total weight loss (%TWL) at 12 months. Secondary outcomes were the incidence of adverse events, amelioration of metabolic laboratory parameters, and improvement in quality of life and eating behavior. Results: Forty patients meeting the eligibility criteria were enrolled from October 2017 to July 2018. Technical and clinical success rates were similar between the groups. At 12 months, the mean %TWL was 8.3% +/- 5.5% in the APC alone group versus 7.5% +/- 7.7% in the Fl S-APC group (P = .71). The pre-revisional % solid gastric retention at 1 hour positively correlated with the probability of achieving >= 10% TWL at 12 months. Both groups experienced significant reductions in low-density lipoprotein and triglyceride levels at 12 months, and improvement in eating behavior and quality of life at 3 months. There were 2 cases of stenoses (1 from each group), which were successfully treated with endoscopic balloon dilation. Conclusion: APC alone is similar to FTS-APC in terms of technical and clinical outcomes within 1 year of followup.
  • conferenceObject
    ENDOSCOPIC VACUUM THERAPY FOR ESOPHAGEAL POST-MEGASTENT PERFORATION.
    (2018) BRUNALDI, Vitor O.; RICCIOPPO, Daniel; MOURA, Diogo T. de; MINATA, Mauricio K.; MORITA, Flavio Hiroshi A.; ROCHA, Rodrigo S.; FARIAS, Galileu F.; SANTO, Marco Aurelio; MOURA, Eduardo G. de
  • conferenceObject
    FULL-THICKNESS ENDOSCOPIC SUTURING PLUS APC VERSUS APC ALONE TO TREAT WEIGHT REGAIN FOLLOWING ROUX-EN-Y GASTRIC BYPASS: AN INTERIM ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL
    (2019) BRUNALDI, Vitor O.; FARIAS, Galileu F.; REZENDE, Daniel T.; NUNES, Gabriel C.; MOURA, Diogo T. de; NETO, Manoel Galvao; SOUZA, Thiago F.; RICCIOPPO, Daniel; SANTO, Marco Aurelio; MOURA, Eduardo G. de