ESTER CERDEIRA SABINO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Patologia, Faculdade de Medicina - Docente
LIM/46 - Laboratório de Parasitologia Médica, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/46 - Laboratório de Parasitologia Médica, Hospital das Clínicas, Faculdade de Medicina - Líder
17 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 17
conferenceObject COCULTURE OF ENDOTHELIAL CELLS AND MONOCYTES AS A POTENTIAL MODEL TO STUDY DENGUE PATHOGENESIS AND SCREEN COMPOUNDS WITH THERAPEUTIC POTENTIAL(2017) CARDOZO, Francielle T.; ROMANO, Camila M.; SABINO, Ester C.conferenceObject RELATIONSHIP OF GALECTIN-3 BIOMARKER FOR CLINICAL OUTCOMES IN A CHAGAS DISEASE COHORT FROM A BRAZILIAN ENDEMIC REGION(2021) MOREIRA, Carlos H.; FERNANDES, Fabio F.; OLIVEIRA, Lea C. De; BIERRENBACH, Ana L.; CARDOSO, Clareci; LORENZO, Claudia Di; FERREIRA, Ariela M.; VIEIRA, Thallyta M.; DAMASCENO, Renata F.; HAIKAL, Desiree S.; QUINTINO, Nayara D.; NUNES, Maria do Carmo; RIBERIO, Antonio Luiz; SABINO, Ester C.- ELISA Saliva for Trypanosoma cruzi Antibody Detection: An Alternative for Serological Surveys in Endemic Regions(2020) OLIVEIRA, Lea Campos de; PEREIRA, Natalia Bueno; MOREIRA, Carlos Henrique Valente; BIERRENBACH, Ana Luiza; SALLES, Flavia Cristina; SOUZA-BASQUEIRA, Marcela de; MANULI, Erika Regina; FERREIRA, Ariela Mota; OLIVEIRA, Claudia Di Lorenzo; CARDOSO, Clareci Silva; RIBEIRO, Antonio Luiz P.; SABINO, Ester CerdeiraChagas is a neglected disease endemic in Latin America. Vector transmission control had been aggressively performed. Recent entomological surveillance in Brazil has revealed natural infection rates ranging from 0.40% to 0.52%. Although serological surveys are complex to develop, they are important for disease control. In this study, we validated the use of saliva in ELISA commercial kits with a cohort of 100 patients with Chagas disease followed at Hospital das Clinicas in Sao Paulo, Brazil, and 50 healthy controls. Five ELISA kits for detecting antibodies against Trypanosome cruzi were tested. The best discrimination between Chagas patients and controls was observed with the Wiener kit, which yielded a sensitivity of 97% and a specificity of 100%. Our findings reveal that the use of saliva may be an alternative to large-scale screening surveys in detecting T. cruzi antibodies; it is a noninvasive sample collection method potentially key to large-scale screening in children.
conferenceObject CIRCULATING MIRNAS PROFILE AS POTENTIAL SIGNATURE OF BENZNIDAZOLE TREATMENT TOXICITY IN CHAGAS PATIENTS(2017) CANDIDO, Darlan da Silva; CUNHA-NETO, Edecio; RIGAUD, Vagner O.; OLIVEIRA, Lea C. de; MOREIRA, Carlos Henrique V.; JUNIOR, Nelson G.; SOUZA, Marcela de; SABINO, Ester C.; FERREIRA, Ludmila R.conferenceObject POTENTIATION OF BENZNIDAZOLE EFFECT BY COADMINISTRATION OF REPURPOSED DRUGS ACTING IN THE INVASION OF HOST CELLS BY TRYPANOSOMA CRUZI(2017) PANDEY, Ramendra P.; SAVOIA, Marilda; SABINO, Ester; KALIL, Jorge; CUNHA-NETO, EdecioconferenceObject CHAGAS DISEASE: A PROSPECTIVE THERAPEUTIC COHORT WITH 12 MONTHS FOLLOW-UP, ANALYZING ADVERSE DRUG REACTIONS, THERAPEUTIC FAILURE AND SEEKING FOR BIOMARKERS""(2017) MOREIRA, Carlos H.; CARVALHO, Noemia B.; FERRUFINO, Rosario Q.; OLIVEIRA, Lea C.; LINDOSO, Jose A.; MANULI, Erika; SOUZA, Marcela De; SABINO, Ester C.conferenceObject FROM DECIPHERING THE SPECIFIC IMMUNE RESPONSE TO A NOVEL BIOMARKER FOR MONITORING CHAGAS DISEASE(2017) ZREIN, Maan; SABINO, Ester C.conferenceObject EVALUATING VIRAL GENOMICS AND DISEASE SEVERITY USING NANOPORE SEQUENCING: A PROOF-OF-CONCEPT ANALYSIS(2021) MARQUES, Beatriz Carvalho; CANDIDO, Darlan Silva; ESTOFOLETE, Cassia Fernanda; SACCHETTO, Livia; DUTRA, Karina Rocha; SALLES, Flavia; DOURADO, Fernanda Simoes; SABINO, Ester Cerdeira; FARIA, Nuno; NOGUEIRA, Mauricio LacerdaconferenceObject SYNDECAN-1 AS A BIOMARKER OF SEVERITY IN ACUTE YELLOW FEVER(2019) SOUSA, Francielle Tramontini Gomes de; MANULI, Erika R.; ZANELLA, Luiz G.; HO, Yeh-Li; NETTO, Lucas Chaves; MARMORATO, Mariana P.; DIAS, Juliana Z.; THOMAZELLA, Mateus V.; CORREIA, Carolina A.; SILVEIRA, Cassia G.; COSTA, Priscilla R.; PEREIRA, Geovana M.; FERREIRA, Midia S.; ROMANO, Camila M.; KALLAS, Esper G.; HARRIS, Eva; SABINO, Ester C.conferenceObject GALECTIN 3 IS ASSOCIATED WITH THE MORE SEVERE FORM OF CHAGAS CARDIOMYOPATHY(2015) FERNANDES, Fabio; MOREIRA, Carlos H.; OLIVEIRA, Lea C.; SOUZA, Marcela; MADY, Charles; IANNI, Barbara M.; MANULI, Erika; SABINO, Ester C.