MARIANA MATERA VERAS
Projetos de Pesquisa
Unidades Organizacionais
LIM/05 - Laboratório de Poluição Atmosférica Experimental, Hospital das Clínicas, Faculdade de Medicina - Líder
13 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 13
conferenceObject IMPACTS OF RECREATIONAL USE OF CANNABIS SATIVA ON GESTATIONAL AND DEVELOPMENTAL OUTCOMES IN MICE: PRELIMINARY RESULTS(2015) BENEVENUTO, S. G. M.; BELOTTI, L.; COSTA, N. S. X.; DOLHNIKOFF, M.; RIBEIRO JUNIOR, G.; LOURENCO, D. T.; VERAS, M. M.conferenceObject Chronicle air pollution exposition and semen quality in hypercolesterolemic mice(2013) PERES, M. A.; CASTRO, K.; RIBEIRO-JUNIOR, G.; MENDES, C.; LOSANO, J.; VERAS, M.; SALDIVA, P.Air pollution (AP) is associated to lose of semen quality. It is also known that some population groups are more susceptible to atmospheric pollution effects due to a pre-existing health condition. This work detailed the effects AP in semen quality of mice knockout for low density lipoprotein receptor that represents an important risk group of human population. Animals were exposed to AP during pre and/or post natal period until adult life, with or without hypercholesterolemic diet. Semen analysis comprised sperm number and morphology, membrane, acrosome and DNA integrity, mitochondrial activity, oxidative stress and cytokines expression of seminal vesicle. The combination of the three factors (AP pre/post natal exposure and hypercholesterolemia) negatively impacted DNA fragmentation, mitochondrial activity, membrane integrity and oxidative stress. Other parameters did not show significant differences. Air pollution combined with hypercholesterolemia condition potentiated the negative effects on important parameters of semen leading male mice to present low fertility/infertility.- NEGATIVE EFFECTS OF SMOKING MARIJUANA DURING PREGNANCY ON THE PLACENTA: EXPERIMENTAL EVIDENCE(2019) VERAS, Mariana; BENEVENUTO, Sarah; TORRES, Janaina; YARIWAKE, Victor; MORAES, Thamires; SILVA, Iran
- ADVANCED MATERNAL AGE AND PLACENTAL MORPHOFUNCTIONAL CHANGES: AN EXPERIMENTAL STUDY IN MICE(2017) TORRES, J. I.; NEVES, I. A.; YARIWAKE, V. Y.; MIGLINO, M. A.; VERAS, M. M.
- Ambient levels of concentrated PM2.5 affects cell kinetics in adrenal glands: an experimental study in mice(2017) FUCHS, Luiz Fernando Portugal; VERAS, Mariana Matera; SALDIVA, Paulo Hilario Nascimento; SASSO, Gisela Rodrigues da Silva; CARVALHO, Katia Candido; SIMOES, Manuel de Jesus; SOARES JR., Jose Maria; BARACAT, Edmund ChadaWe evaluated the effects of air pollution on the adrenal cortex using 30 female mice divided into two groups of fifteen animals each. One group was conditioned daily in a chamber with exposure to particulate matter (PM) 2.5 mu m (GExp). Animals were exposed on daily basis in an ambient particles concentrator during the period of time enough to reach an accumulated dose of 600 mu g/m(3), which corresponds to a 24-h exposure of 25 mu g/m(3) that approximates to the annual mean of PM2.5 in Sao Paulo. The other group was allocated to another chamber with filtered air (GCrt). After euthanasia, the adrenals underwent histological processing and immunohistochemistry staining for Ki-67 and cleaved caspase-3. Histomorphometry of the adrenal glands in GExp showed increased thickness of the zona glomerulosa, while in GCrt; the adrenal glands from GExp had higher Ki-67 immunostaining scores in the zona reticularis than those from GCrt. The adrenal from GExp showed higher cleaved caspase-3 immunoreactivity in the zona fasciculata than the unexposed group (GCrt). The homeostasis index indicated higher cell proliferation in the zona glomerulosa and zona reticularis in GExp than in GCrt. Our data indicate that PM2.5 air pollution induces alterations on cell kinetics in mouse adrenal glands.
- SERUM OF PATIENTS WITH PREECLAMPSIA ACTIVATES UPR-PERK PATHWAY IN HUMAN TROPHOBLAST CELL LINE HTR8/SVNEO(2019) CASTRO, Karla; PRADO, Karen; LORENZON-OJEA, Aline; FRANCISCO, Rossana; ZUGAIB, Marcelo; HOSHIDA, Mara; ALVES, Eliane; VERAS, Mariana; BEVILACQUA, Estela
conferenceObject FINE PARTICULATE MATTER IN THE AIR WITHIN THE LIMITS RECOMMENDED BY WHO ALTERS PLACENTAL STRUCTURE(2014) SOTO, Sonia; LOPES, Karen; OLIVEIRA, Ivone; SOUZA, Regiane; MARCHESI, Guilherme; VERAS, Mariana; HEIMANN, JoelconferenceObject FINE INHALABLE PARTICULATE MATTER (PM2.5) PRESENT IN AIR POLLUTION AND ITS EFFECTS ON MALE GERM CELLS CHROMATIN PACKAGING.(2023) TAMASHIRO, Leticia Kaory; YARIWAKE, Victor Yuji; VERAS, Mariana Matera; BERTOLLA, Ricardo P.; INTASQUI, PaulaconferenceObject EFFECT OF THE EXPOSURE TO FINE INHALABLE PARTICULATE MATTER (PM2.5) ON SPERM FUNCTIONAL QUALITY OF MICE.(2020) INTASQUI, Paula; TAMASHIRO, Leticia Kaory; YARIWAKE, Victor Yuji; SOUZA, Rosana Xavier; KANASHIRO, Camila Matie; VERAS, Mariana Matera- EXPRESSION OF ENDOPLASMIC RETICULUM STRESS MARKERS IN CHORIONIC VILLI TREATED WITH SERUM FROM PATIENTS WITH PRE-ECLAMPSIA(2017) CASTRO, Karla; PRADO, Karen; LORENZON-OJEA, Aline; SMUZCEK, Basilio; HOSHIDA, Mara; FRANCISCO, Rossana; ZUGAIB, Marcelo; ALVES, Eliane; VERAS, Mariana; BEVILACQUA, Estela