GABRIELA LIBERATO

Índice h a partir de 2011
6
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

Filtros

Mostrar mais
Limpar filtros

Configurações

Colaboração internacional: Argentina ×

Resultados de Busca

Agora exibindo 1 - 1 de 1
  • article 10 Citação(ões) na Scopus
    Accuracy of Cardiac Magnetic Resonance Imaging in Diagnosing Pediatric Cardiac Masses A Multicenter Study
    (2022) BEROUKHIM, Rebecca S.; GHELANI, Sunil; ASHWATH, Ravi; BALASUBRAMANIAN, Sowmya; BIKO, David M.; BUDDHE, Sujatha; CAMPBELL, M. Jay; CROSS, Russell; FESTA, Pierluigi; GRIFFIN, Lindsay; GROTENHUIS, Heynric; HASBANI, Keren; HASHEMI, Sassan; HEGDE, Sanjeet; HUSSAIN, Tarique; JAIN, Supriya; KIAFFAS, Maria; KUTTY, Shelby; LAM, Christopher Z.; LIBERATO, Gabriela; MERLOCCO, Anthony; MISRA, Nilanjana; MOWERS, Katie L.; MUNIZ, Juan Carlos; NUTTING, Arni; PARRA, David A.; PATEL, Jyoti K.; PEREZ-ATAYDE, Antonio R.; PRASAD, Deepa; ROSENTAL, Carlos F.; SHAH, Amee; SAMYN, Margaret M.; SLEEPER, Lynn A.; SLESNICK, Timothy; VALSANGIACOMO, Emanuela; GEVA, Tal
    BACKGROUND After diagnosis of a cardiac mass, clinicians must weigh the benefits and risks of ascertaining a tissue diagnosis. Limited data are available on the accuracy of previously developed noninvasive pediatric cardiac magnetic resonance (CMR)-based diagnostic criteria. OBJECTIVES The goals of this study were to: 1) evaluate the CMR characteristics of pediatric cardiac masses from a large international cohort; 2) test the accuracy of previously developed CMR-based diagnostic criteria; and 3) expand diagnostic criteria using new information. METHODS CMR studies (children 0-18 years of age) with confirmatory histological and/or genetic diagnosis were analyzed by 2 reviewers, without knowledge of prior diagnosis. Diagnostic accuracy was graded as: 1) single correct diagnosis; 2) correct diagnosis among a differential; or 3) incorrect diagnosis. RESULTS Of 213 cases, 174 (82%) had diagnoses that were represented in the previously published diagnostic criteria. In 70% of 174 cases, both reviewers achieved a single correct diagnosis (94% of fibromas, 71% of rhabdomyomas, and 50% of myxomas). When #2 differential diagnoses were included, both reviewers reached a correct diagnosis in 86% of cases. Of 29 malignant tumors, both reviewers indicated malignancy as a single diagnosis in 52% of cases. Including #2 differential diagnoses, both reviewers indicated malignancy in 83% of cases. Of 6 CMR sequences examined, acquisition of first-pass perfusion and late gadolinium enhancement were independently associated with a higher likelihood of a single correct diagnosis. CONCLUSIONS CMR of cardiac masses in children leads to an accurate diagnosis in most cases. A comprehensive imaging protocol is associated with higher diagnostic accuracy. Crown