ANDRE PEDRINELLI
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
16 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 16
- Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement (vol 24, pg 1, 2021)(2021) HAMILTON, Blair R.; LIMA, Giscard; BARRETT, James; SEAL, Leighton; KOLLIARI-TURNER, Alexander; WANG, Guan; KARANIKOLOU, Antonia; BIGARD, Xavier; LOLLGEN, Herbert; ZUPET, Petra; IONESCU, Anca; DEBRUYNE, Andre; JONES, Nigel; VONBANK, Karin; FAGNANI, Federica; FOSSATI, Chiara; CASASCO, Maurizio; CONSTANTINOU, Demitri; WOLFARTH, Bernd; NIEDERSEER, David; BOSCH, Andrew; MUNIZ-PARDOS, Borja; CASAJUS, Jose Antonio; SCHNEIDER, Christian; LOLAND, Sigmund; VERROKEN, Michele; MARQUETA, Pedro Manonelles; ARROYO, Francisco; PEDRINELLI, Andre; NATSIS, Konstantinos; VERHAGEN, Evert; ROBERTS, William O.; LAZZOLI, Jose Kawazoe; FRIEDMAN, Rogerio; ERDOGAN, Ali; CINTRON, Ana V.; YUNG, Shu-Hang Patrick; RENSBURG, Dina C. Janse van; RAMAGOLE, Dimakatso A.; ROZENSTOKA, Sandra; DRUMMOND, Felix; PAPADOPOULOU, Theodora; KUMI, Paulette Y. O.; TWYCROSS-LEWIS, Richard; HARPER, Joanna; SKIADAS, Vasileios; SHURLOCK, Jonathan; TANISAWA, Kumpei; SETO, Jane; NORTH, Kathryn; ANGADI, Siddhartha S.; MARTINEZ-PATINO, Maria Jose; BORJESSON, Mats; LUIGI, Luigi Di; DOHI, Michiko; SWART, Jeroen; BILZON, James Lee John; BADTIEVA, Victoriya; ZELENKOVA, Irina; STEINACKER, Juergen M.; BACHL, Norbert; PIGOZZI, Fabio; GEISTLINGER, Michael; GOULIS, Dimitrios G.; GUPPY, Fergus; WEBBORN, Nick; YILDIZ, Bulent O.; MILLER, Mike; SINGLETON, Patrick; PITSILADIS, Yannis P.
- Isokinetic muscle strength and knee function associated with double femoral pin fixation and fixation with interference screw in anterior cruciate ligament reconstruction(2012) FERNANDES, Tiago Lazzaretti; PROTTA, Thiago Rocha; FREGNI, Felipe; BOLLIGER NETO, Raul; PEDRINELLI, Andre; CAMANHO, Gilberto Luis; HERNANDEZ, Arnaldo JoseIntensive scheduling in sports requires athletes to resume physical activity shortly after injury. The purpose of this study was to investigate early isokinetic muscle strength and knee function on bone-patellar tendon-bone (BPTB) ACL reconstruction with double femoral pin fixation or interference screw technique. A prospective study was conducted from 2008 to 2009, with 48 athletes who received femoral BPTB fixation with interference screw (n = 26) or double pin (n = 22). Clinical (IKDC objective score and hop test) and isokinetic muscle strength (peak torque (PT), PT/body weight and flexion/extension rate (F/E) in 60 and 240A degrees/s) were analyzed at 6 months of follow-up. Analysis at baseline showed no differences between groups before surgery related to age, gender, associated injury, Tegner or Lysholm score; thus showing that groups were similar. During follow-up, however, there were significant differences between the two groups in some of the isokinetic muscle strength: PT/BW 60A degrees/s (Double Pin = 200% +/- A 13% vs. Interference Screw = 253% +/- A 16%*, *P = 0.01); F/E 60A degrees/s (Double Pin = 89% +/- A 29%* vs. Interference Screw = 74% +/- A 12%, *P = 0.04). No statistical differences between groups were observed on IKDC objective score, hop test and complications. The significant muscle strength outcome of the interference screw group found in this study gives initial evidence that this fixation technique is useful for athletes that may need accelerated rehabilitation. Early return to sports ability signaled by isokinetic muscle strength is of clinical relevance as it is one of the main goals for athletes' rehabilitation. III.
- The FIFA medical emergency bag and FIFA 11 steps to prevent sudden cardiac death: setting a global standard and promoting consistent football field emergency care(2013) DVORAK, Jiri; KRAMER, Efraim B.; SCHMIED, Christian M.; DREZNER, Jonathan A.; ZIDEMAN, David; PATRICIOS, Jon; CORREIA, Luis; PEDRINELLI, Andre; MANDELBAUM, BertLife-threatening medical emergencies are an infrequent but regular occurrence on the football field. Proper prevention strategies, emergency medical planning and timely access to emergency equipment are required to prevent catastrophic outcomes. In a continuing commitment to player safety during football, this paper presents the FIFA Medical Emergency Bag and FIFA 11 Steps to prevent sudden cardiac death. These recommendations are intended to create a global standard for emergency preparedness and the medical response to serious or catastrophic on-field injuries in football.
- Joint position statement of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the IOC framework on fairness, inclusion and non-discrimination based on gender identity and sex variations(2022) PIGOZZI, Fabio; BIGARD, Xavier; STEINACKER, Juergen; WOLFARTH, Bernd; BADTIEVA, Victoriya; SCHNEIDER, Christian; SWART, Jeroen; BILZON, James Lee John; CONSTANTINOU, Demitri; DOHI, Michiko; LUIGI, Luigi Di; FOSSATI, Chiara; BACHL, Norbert; LI, Guoping; PAPADOPOULOU, Theodora; CASASCO, Maurizio; RENSBURG, Dina Christina (Christa) Janse van; KAUX, Jean-Francois; ROZENSTOKA, Sandra; CASAJUS, Jose-Antonio; ZELENKOVA, Irina; AK, Emre; ULKAR, Bulent; ARROYO, Francisco; IONESCU, Anca; PEDRINELLI, Andre; MILLER, Mike; SINGLETON, Patrick; SHROFF, Malav; WEBBORN, Nick; BARRETT, James; HAMILTON, Blair; GEISTLINGER, Michael; BELTRAMI, Gianfranco; MIGLIORINI, Sergio; DIENSTBACH-WECH, Lenka; BERMON, Stephane; PITSILADIS, Yannis P.The IOC recently published its framework on fairness, inclusion and non-discrimination based on gender identity and sex variations. This framework is drafted mainly from a human rights perspective, with less consideration for medical/scientific issues. The framework places the onus for gender eligibility and classification entirely on the International Federations (IFs), even though most will not have the capacity to implement the framework. The position of no presumption of advantage is contrary to the 2015 IOC consensus. Implementation of the 2021 framework will be a major challenge for IFs that have already recognised the inclusion of trans and women athletes with differences of sexual development (DSD) using a scientific/medical solution. The potential consequences for sports that need to prioritise fairness or safety could be one of two extremes (1) exclusion of all transgender or DSD athletes on the grounds of advantage or (2) self-identification that essentially equates to no eligibility rules. Exclusion of all transgender or DSD athletes is contrary to the Olympic charter and unlawful in many countries. While having no gender eligibility rules, sport loses its meaning and near-universal support. Athletes should not be under pressure to undergo medical procedures or treatment to meet eligibility criteria. However, if an athlete is fully informed and consents, then it is their free choice to undergo carefully considered or necessary interventions for gender classification for sport to compete fairly and safely in their chosen gender. Free choice is a fundamental human right, but so is the right to fair and safe competition.
- The influence of femoral tunnel position in single-bundle ACL reconstruction on functional outcomes and return to sports(2014) FERNANDES, Tiago Lazzaretti; FREGNI, Felipe; WEAVER, Kayleen; PEDRINELLI, Andre; CAMANHO, Gilberto Luis; HERNANDEZ, Arnaldo JoseThe purpose of this study was to radiographically investigate the influence of femoral tunnel placement in ACL reconstruction on early outcomes and return to sports due to anatomic and nonanatomic positioning. A prospective study was conducted from 2008 to 2010, with 86 athletes who underwent ACL reconstruction between anteromedial (AM) footprint and high AM position. Knee functional outcomes (IKDC objective and subjective, Tegner score, and Lysholm scale) return to sports and complications were analyzed at 6- and 12-month follow-up. At follow-up, it was observed that tunnel projection along Blumensaat's line was correlated with functional outcomes on Tegner scale (at 6 and 12 months) and IKDC subjective (at 12 months). There was a significant difference in mean tunnel projection along Blumensaat's line when analyzing return to sports (73 +/- A 1.4 and 79 +/- A 1.7 %, respectively, for projections on return vs. no return to sports, p = 0.02) and complications (73 +/- A 1.3 vs. 78 +/- A 1.6 %, respectively, for projections on no complications vs. complications, p = 0.03). No differences were stated on coronal view. These correlations between tunnel positioning on functional outcomes could not be explained by demographic or baseline characteristics. The clinical relevance of this study is that tunnel positioning along AM footprint and high AM position represented by tunnel projection along Blumensaat's line is associated with early return to sports on previous Tegner level and better functional outcome in athletes. III.
- Response to the United Nations Human Rights Council's Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research(2021) HAMILTON, Blair R.; MARTINEZ-PATINO, Maria Jose; BARRETT, James; SEAL, Leighton; TUCKER, Ross; PAPADOPOULOU, Theodora; BIGARD, Xavier; KOLLIARI-TURNER, Alexander; LOLLGEN, Herbert; ZUPET, Petra; IONESCU, Anca; DEBRUYNE, Andre; JONES, Nigel; STEINACKER, Juergen M.; VONBANK, Karin; LIMA, Giscard; FAGNANI, Federica; FOSSATI, Chiara; LUIGI, Luigi Di; PIGOZZI, Fabio; CASASCO, Maurizio; GEISTLINGER, Michael; WOLFARTH, Bernd; SETO, Jane T.; BACHL, Norbert; TWYCROSS-LEWIS, Richard; NIEDERSEER, David; BOSCH, Andrew; SWART, Jeroen; CONSTANTINOU, Demitri; MUNIZ-PARDOS, Borja; CASAJUS, Jose Antonio; BADTIEVA, Victoriya; ZELENKOVA, Irina; BILZON, James L. J.; DOHI, Michiko; SCHNEIDER, Christian; LOLAND, Sigmund; VERROKEN, Michele; MARQUETA, Pedro Manonelles; ARROYO, Francisco; PEDRINELLI, Andre; NATSIS, Konstantinos; VERHAGEN, Evert; ROBERTS, William O.; LAZZOLI, Jose Kawazoe; FRIEDMAN, Rogerio; ERDOGAN, Ali; CINTRON, Ana V.; YUNG, Shu-Hang Patrick; RENSBURG, Dina C. Janse van; RAMAGOLE, Dimakatso A.; ROZENSTOKA, Sandra; DRUMMOND, Felix; WEBBORN, Nick; GUPPY, Fergus M.; PITSILADIS, Yannis P.
- Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement(2021) HAMILTON, Blair R.; LIMA, Giscard; BARRETT, James; SEAL, Leighton; KOLLIARI-TURNER, Alexander; WANG, Guan; KARANIKOLOU, Antonia; BIGARD, Xavier; LOLLGEN, Herbert; ZUPET, Petra; IONESCU, Anca; DEBRUYNE, Andre; JONES, Nigel; VONBANK, Karin; FAGNANI, Federica; FOSSATI, Chiara; CASASCO, Maurizio; CONSTANTINOU, Demitri; WOLFARTH, Bernd; NIEDERSEER, David; BOSCH, Andrew; MUNIZ-PARDOS, Borja; CASAJUS, Jose Antonio; SCHNEIDER, Christian; LOLAND, Sigmund; VERROKEN, Michele; MARQUETA, Pedro Manonelles; ARROYO, Francisco; PEDRINELLI, Andre; NATSIS, Konstantinos; VERHAGEN, Evert; ROBERTS, William O.; LAZZOLI, Jose Kawazoe; FRIEDMAN, Rogerio; ERDOGAN, Ali; CINTRON, Ana V.; YUNG, Shu-Hang Patrick; RENSBURG, Dina C. Janse van; RAMAGOLE, Dimakatso A.; ROZENSTOKA, Sandra; DRUMMOND, Felix; PAPADOPOULOU, Theodora; KUMI, Paulette Y. O.; TWYCROSS-LEWIS, Richard; HARPER, Joanna; SKIADAS, Vasileios; SHURLOCK, Jonathan; TANISAWA, Kumpei; SETO, Jane; NORTH, Kathryn; ANGADI, Siddhartha S.; MARTINEZ-PATINO, Maria Jose; BORJESSON, Mats; LUIGI, Luigi Di; DOHI, Michiko; SWART, Jeroen; BILZON, James Lee John; BADTIEVA, Victoriya; ZELENKOVA, Irina; STEINACKER, Juergen M.; BACHL, Norbert; PIGOZZI, Fabio; GEISTLINGER, Michael; GOULIS, Dimitrios G.; GUPPY, Fergus; WEBBORN, Nick; YILDIZ, Bulent O.; MILLER, Mike; SINGLETON, Patrick; PITSILADIS, Yannis P.Sport is historically designated by the binary categorization of male and female that conflicts with modern society. Sport's governing bodies should consider reviewing rules determining the eligibility of athletes in the female category as there may be lasting advantages of previously high testosterone concentrations for transwomen athletes and currently high testosterone concentrations in differences in sex development (DSD) athletes. The use of serum testosterone concentrations to regulate the inclusion of such athletes into the elite female category is currently the objective biomarker that is supported by most available scientific literature, but it has limitations due to the lack of sports performance data before, during or after testosterone suppression. Innovative research studies are needed to identify other biomarkers of testosterone sensitivity/responsiveness, including molecular tools to determine the functional status of androgen receptors. The scientific community also needs to conduct longitudinal studies with specific control groups to generate the biological and sports performance data for individual sports to inform the fair inclusion or exclusion of these athletes. Eligibility of each athlete to a sport-specific policy needs to be based on peer-reviewed scientific evidence made available to policymakers from all scientific communities. However, even the most evidence-based regulations are unlikely to eliminate all differences in performance between cisgender women with and without DSD and transwomen athletes. Any remaining advantage held by transwomen or DSD women could be considered as part of the athlete's unique makeup.
- DURING THE CORONAVIRUS (COVID-19) PANDEMIC, DOES WEARING A MASK IMPROVE OR WORSEN PHYSICAL PERFORMANCE?(2020) SANTOS-SILVA, Paulo Roberto; GREVE, Julia Maria D'Andrea; PEDRINELLI, AndreA mask is a simple device yet it provides high levels of protection. As the virus affects mainly the respiratory tract - the nose, mouth, and lungs - it is highly contagious when people sneeze or cough, or exchange respiratory droplets with other people.This exchange is also promoted when a person is performing physical exercise. Although a mask provides some protection, it does not eliminate the need for social distancing. Around 25% of people infected with the new coronavirus may show no symptoms, yet still transmit the virus. One of the main problems with wearing a mask is that it hinders breathing, with the mask gradually becoming damp, increasing its resistance to air intake. Wearing a mask while performing physical activity requires a period of adaptation, as the flow of air to the lungs is reduced, requiring a reduction in the normal rhythm until the wearer has managed to adapt to it. Vigorous and intense exercise can cause inflammatory activity to increase, and should be minimized in order to protect the immune system. Secretory immunoglobulin A (IgA) is an antibody protein used by the immune system to neutralize pathogens, including viruses, and decreases with intense exercise. Exercise is considered intense when it is necessary to breathe through the mouth to eliminate the higher concentrations of CO2, but mouth breathing is associated with infections of the upper respiratory tract. Preference should be given to light to moderate exercise, around three times a week. Wearing a mask, and training in nasal breathing are the best and safest ways to reduce the entry of particles, and should be encouraged during this COVID-19 pandemic.
- Protecting olympic participants from COVID-19: the trialled and tested process(2021) PIGOZZI, Fabio; WOLFARTH, Bernd; RODRIGUEZ, Ana Cintron; STEINACKER, Juergen Michael; BADTIEVA, Victoriya; BILZON, James Lee John; SCHNEIDER, Christian; ROBERTS, William O.; SWART, Jeroen; CONSTANTINOU, Demitri; DOHI, Michiko; PAPADOPOULOU, Theodora; HUTCHINSON, Mark; LUIGI, Luigi Di; ZAHAR, Maher; SO, Raymond; GUPPY, Fergus M.; KAUX, Jean-Francois; MADAHAPOLA, Upul; ROZENSTOKA, Sandra; MARQUETA, Pedro Manonelles; CASAJUS, Jose Antonio; RACINAIS, Sebastien; NATSIS, Konstantinos; ZELENKOVA, Irina; ULKAR, Bulent; OZDEMIR, Elif; ARROYO, Francisco; PEDRINELLI, Andre; MILLER, Mike; BACHL, Norbert; GEISTLINGER, Michael; PITSILADIS, Yannis P.
- Clinical Outcome Evaluation of Anatomic Anterior Cruciate Ligament Reconstruction With Tunnel Positioning Using Gold Standard Techniques: A Systematic Review and Meta-analysis(2021) FERNANDES, Tiago Lazzaretti; MOREIRA, Hugo Henrique; ANDRADE, Renato; SASAKI, Sandra Umeda; BERNARDO, Wanderley Marques; PEDRINELLI, Andre; ESPREGUEIRA-MENDES, Joao; HERNANDEZ, Arnaldo JoseBackground: There have been conflicting results about the theoretical advantages of anatomic double-bundle anterior cruciate ligament (ACL) reconstruction. Purpose: To evaluate the clinical and functional outcomes comparing anatomic single- versus double-bundle techniques, anatomic versus nonanatomic techniques, and transportal versus outside-in tunnel drilling for ACL reconstruction. Study Design: Systematic review; Level of evidence, 3. Methods: A search was performed in the MEDLINE and EMBASE databases up to August 2018 for clinical trials comparing anatomic ACL reconstruction (with tunnel positioning demonstrated using gold standard radiologic techniques) with another technique, with a minimum functional and biomechanical follow-up of 6 months. A meta-analysis was performed to compare clinical and functional outcomes between anatomic single- versus double-bundle reconstruction and between anatomic versus nonanatomic techniques, using the risk difference or the mean difference. Risk of bias of the included studies was assessed using the Newcastle-Ottawa Scale for cohort and case-control studies and the Cochrane Risk of Bias tool and Jadad Score for randomized controlled trials. Results: Included were 15 studies comprising 1290 patients (follow-up, 12-36 months). No significant differences favoring anatomic double-bundle over anatomic single-bundle reconstruction or outside-in over transportal techniques were found. The meta-analyses showed significant differences in the International Knee Documentation Committee (IKDC) objective score (risk difference, -0.14; 95% confidence interval, -0.27 to -0.01) favoring anatomic over nonanatomic reconstruction. No statistically significant differences were found between anatomic and nonanatomic surgical techniques on other functional scores or clinical examination outcomes, including the IKDC subjective score, Lysholm score, Tegner score, KT-1000 arthrometer test, or pivot-shift test. Conclusion: Double-bundle reconstruction was not superior to the single-bundle technique in clinical and functional outcomes. Anatomic ACL reconstruction shows significantly superior results over nonanatomic ACL reconstruction, reinforcing the anatomic technique as the gold standard choice for clinical practice.