CRISTOVAO MACHADO BARBOSA NETO
Projetos de Pesquisa
Unidades Organizacionais
10 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 10
conferenceObject DO THE REGULATION OF MATRIX METALLOPROTEINASES AND TISSUE INHIBITORS OF MATRIX METALLOPROTEINASES HAVE ANY ASSOCIATION WITH PEYRONIE'S DISEASE?(2020) NETO, Cristovao Barbosa; REIS, Sabrina T.; ARANTES, Gabriel; NASCIMENTO, Bruno; SAYAO, Rogerio; LEITE, Katia Ramos; SROUGI, Miguel; NAHAS, William; CURY, JoseconferenceObject INCIDENCE OF CLIMACTURIA IN MEN WITH SEXUAL DYSFUNCTION AFTER RADICAL PROSTATECTOMY(2022) GAMBERINI, P.; RIBEIRO, H.; SAYAO, R.; PEDRENHO, R.; BARBOSA NETO, C.; GOES, P.; NASCIMENTO, B.; BESSA JUNIOR, J. de; NAHAS, W.; SROUGI, M.; AMOEDO, F.conferenceObject DOES STENTED REIMPLANTATION IN RENAL TRANSPLANTATION INCREASE THE RISK OF URINARY INFECTION?(2018) BARBOSA NETO, Cristovao; ILARIO, Eder; MELLO, Marcos; KANASHIRO, Hideki; LOCALLI, Rafael; BARONE, Hugo; FALCI JUNIOR, Renato; NAHAS, William; PIOVESAN, Affonso- The role of bladder diverticula in the prevalence of acute urinary retention in patients with BPH who are candidates to surgery(2018) ISCAIFE, Alexandre; ARFOS, Gabriel dos; NETO, Cristovao Barbosa; NAHAS, Willian Carlos; SROUGI, Miguel; ANTUNES, Alberto AzoubelIntroduction: The urinary bladder diverticula (BD) secondary to benign prostatic hyperplasia (BPH) is a complication that can lead to urinary stasis, stone, urinary tract infection (UTI) and tumors. It's role in acute urinary retention (AUR) is not totally understood. Objectives: To determine the effect of BD size on AUR rates in patients with BPH candidates to surgery. Subjects and Methods: We performed a retrospective cohort study of 47 patients with BPH and BD who underwent BPH surgery associated to complete bladder diverticulectomy from 2006 to 2016. We analyzed risk factors for AUR in patients with BD using univariate, multivariate and correlation analysis. Results: There was a difference in the size of the diverticula, with 6.8 cm vs. 4.5 cm among patients with and without AUR respectively (p=0.005). The ROC curve showed a correlation between the size of BD and the risk of AUR. The value of 5.15 cm presented a sensitivity of 73% and a specificity of 72%. The area under the curve was 0.75 (p=0.01). Comparing groups with BD > 5.0 cm vs. <= 5.0 cm, the AUR incidence was 74% and 27.8% respectively with an OR of 2.65 (1.20-5.85) (p=0.005). In the multivariate analysis, only the size of the diverticula reached statistical significance (p=0.012). Conclusions: The diameter of BD is an independent risk factor for AUR in patients with BPH and BD who are candidates to surgery. A diameter greater than 5.15 cm increases the risk of AUR.
conferenceObject CORRELATION BETWEEN LIBIDO AND TESTOSTERONE: ESTRADIOL RATIO IN MEN WITH SEXUAL DYSFUNCTION(2022) PEDRENHO NETO, R.; NUNES, R. dos Santos Sobreira; NASCIMENTO, C. G. B.; BARBOSA NETO, C. Machado; BESSA JUNIOR, J. de; SROUGI, M.; NAHAS, W. CarlosconferenceObject FACTORS ASSOCIATED WITH THE DECREASE IN ORGASM INTENSITY IN PATIENTS WHO UNDERWENT TO RADICAL PROSTATECTOMY(2022) GAMBERINI, P.; NASCIMENTO, B.; BARBOSA NETO, C.; PEDRENHO, R.; GOES, P.; BESSA JUNIOR, J. de; SPHAIR, J.; NAHAS, W.; SROUGI, M.conferenceObject COMPARISON OF NON-INVASIVE MEASUREMENTS OF PENILE CURVATURE IN PEYRONIE'S DISEASE(2022) PEDRENHO NETO, R.; NASCIMENTO, C. G. B.; BARBOSA NETO, C. Machado; BESSA JUNIOR, J. de; SROUGI, M.; NAHAS, W. CarlosconferenceObject COMPARISON OF NON-INVASIVE MEASUREMENTS OF PENILE CURVATURE IN PEYRONIE'S DISEASE(2021) NETO, Rubens Pedrenho; NASCIMENTO, Bruno C. G.; BARBOSA NETO, Cristovao Machado; BESSA JUNIOR, Jose de; SROUGI, Miguel; NAHAS, William CarlosconferenceObject INCIDENCE OF CLIMACTURIA IN MEN WITH SEXUAL DYSFUNCTION AFTER RADICAL PROSTATECTOMY(2020) FILHO, Homero; NASCIMENTO, Bruno; SROUGI, Miguel; CURY, Jose; SAYAO, Rogerio; BARBOSA, Cristovao; NAHAS, William; GOES, Plinio; ANDURTE, Sergio; CRUVINEL, Fernando- Downregulation of miR-29b is associated with Peyronie's disease(2022) SANTOS, Vinicius Genuino dos; SANTOS, Gabriel Arantes dos; NETO, Cristovao Barbosa; VIANA, Nayara Izabel; PIMENTA, Ruan; GUIMARAES, Vanessa Ribeiro; CANDIDO, Patricia; ROMAO, Poliana; CAMARGO, Juliana A. de; LEITE, Katia Ramos Moreira; SROUGI, Miguel; CURY, Jose; NAHAS, William C.; REIS, Sabrina ThalitaBackground: Peyronie's disease (PD) is characterized by the formation of fibrous plaque in tunica albuginea, causing several problems in patients. The etiology of this disease is not fully understood, and there are few effective treatments. To better understand the molecular pathways of PD, we studied miR-29b, a microRNA that could be involved with this illness. MicroRNAs are endogenous molecules that act by inhibiting messenger RNA. MiR-29b regulates 11 of 20 collagen genes and the TGF-beta 1 gene, which are related to PD progression. Methods: We compared miR-29b expression in 11 patients with PD and 14 patients without PD (control group). For the patients with PD, we utilized samples from the fibrous plaque (n = 9), from the tunica albuginea (n = 11), and from the corpus cavernosum (n = 8). For the control group, we utilized samples from the tunica albuginea (n = 14) and from the corpus cavernosum (n = 10). MiR-29b expression was determined by q-PCR. Results: We found a downregulation of miR-29b in the fibrous plaque, tunica albuginea and corpus cavernosum of patients with PD in comparison with the control group (p = 0.0484, p = 0.0025, and p = 0.0016, respectively). Conclusion: Although our study has a small sample, we showed for the first time an evidence that the downregulation of miR-29b is associated with PD.