MARCELO ZUGAIB

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Índice h a partir de 2011
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Departamento de Obstetrícia e Ginecologia, Faculdade de Medicina - Docente
LIM/57 - Laboratório de Fisiologia Obstétrica, Hospital das Clínicas, Faculdade de Medicina

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Autor: ZUGAIB, Marcelo × search.filters.applied.f.dateIssued: 2011 × Revista / Livro: Arquivos Brasileiros de Cardiologia ×

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  • article 1 Citação(ões) na Scopus
    Periodontal Disease in Pregnant Patients with Rheumatic Valvular Disease - Clinical and Microbiological Study
    (2011) AVILA, Walkiria Samuel; TIMERMAN, Lilia; ROMITO, Giuseppe Alexandre; MARCELINO, Silvia Linard; LUCIA, Itamara; NEVES, Itagiba; ZUGAIB, Marcelo; GRINBERG, Max
    Background: The periodontal disease during pregnancy of women with rheumatic valve disease imply infective endocarditis risks and higher rate of preterm birth and low birth weight. Objective: To study the periodontal disease rate of women with rheumatic valve disease during pregnancy. Methods: We studied 140 pregnant women who included 70 patients with rheumatic valve disease and 70 healthy women. The periodontal examination included: 1) periodontal clinical exam regard the follow variables: a) probing depth; b) gingival margin; c) clinical attachment level; d) bleeding on probing; e) plaque index and f) gingival index; and 2) microbiological test was performed in samples serum and gingival crevicular fluid and considered positive controls to Porphyromonas gingivalis, Tannerella forsithia e Aggregobacter actinomycetemcomitans. Results: Age and parity were similar between groups; as single or combined the mitral valve disease was prevalent among the rheumatic valve lesion in 45 (32.1%) e 20 (28.5%) cases, respectively. Among the periodontal variables gingival margin (p=0.01) and plaque index (p=0.04) were different between groups. The periodontal disease was identified in 20 (14,3%) pregnant women, seven (10%) of them were patients with valve rheumatic disease and the remain 13 (18,6%) were healthy women, its percentual was not different between groups (p=0,147). Microbiological analyses of oral samples showed higher percentual of P. gingivalis in healthy pregnant women (p=0.004). Conclusion: The clinical and microbiological study during pregnancy showed comparable incidence of periodontal disease between women with rheumatic valve disease and healthy women. (Arq Bras Cardiol 2011;96(4):307-311)