ROSA MARIA FIGUEIREDO VALERIO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
5 resultados
Resultados de Busca
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conferenceObject Intracarotid Ethomidate - WADA Test: A 75 Patient Series(2013) BASTOS, Carla; HOBI, Camila; LIMA FILHO, Humberto; PASSARELLI, Valmir; PINTO, Lecio; JORGE, Carmen; VALERIO, Rosa; CASTRO, LuizconferenceObject Early Postoperative Language Changes in Right and Left Mesial Temporal Sclerosis(2013) CASTRO, Bettina; MESSAS, Cristiane; ALMEIDA, Juliana; JORGE, Carmen; VALERIO, Rosa; WEN, Hung; CASTRO, Luiz- Low prevalence but high specificity of material-specific memory impairment in epilepsy associated with hippocampal sclerosis(2013) CASTRO, Luiz H.; SILVA, Liliane C. A. M.; ADDA, Carla C.; BANASKIWITZ, Natalie H. C.; XAVIER, Alana B.; JORGE, Carmen L.; VALERIO, Rosa M.; NITRINI, RicardoPurposeMaterial-specific memory impairment is used as a lateralizing tool in the evaluation of temporal lobe epilepsy. Lateralizing ability of material-specific memory deficits in temporal lobe epilepsy remains controversial. MethodsWe studied memory impairment profiles of verbal and nonverbal memory deficits with eight memory subtests of four neuropsychological instruments (two verbal and two nonverbal) in 87 right-handed patients with epilepsy associated with unilateral mesial temporal sclerosis (MTS; 44 right - R, 43 left - L) and 42 controls, with an IQ>70, at least 8years of education, and without comorbidities. Key FindingsSelective verbal memory impairment was noted in 11 of 43 or 25.6% of left MTS cases, with 82.2% specificity, whereas selective nonverbal memory impairment was noted in 11 of 42 or 26.2% of right MTS cases, with 92% specificity. Nonlateralizing profiles of memory performance were seen in the remaining 65 of 87 patients. Approximately half (46/87 or 52.9%) of the patients had intact memory function in both modalities, equally distributed between patients with right MTS (23/44) and left MTS (23/43). Global impairment of both memory types was seen in 12 of 87 or 13.8% of patients, equally distributed between the two groups (7/43 left and 5/44 right). SignificanceLateralizing profiles of selective verbal and nonverbal memory deficits are highly specific for left and right MTS, although infrequently encountered in our patients. Nonlateralizing profiles predominated in this population. These findings suggest hemispheric asymmetry memory function, with complex functional interaction of the hippocampi, and possible compensatory mechanisms in the setting of a unilateral lesion.
conferenceObject Differential Reduction in Activation of Language and Executive Function Networks in Right and Left Mesial Temporal Sclerosis Patients in a Language-Based Decision fMRI Paradigm(2013) ALMEIDA, Juliana de; CASTRO, Bettina; ARANTES, Paula; JORGE, Carmen; VALERIO, Rosa; AMARO JR., Edson; CASTRO, LuizconferenceObject Increased Right Hemisphere Activation in a Visual Confrontation Naming Paradigm in Left Mesial Temporal Sclerosis(2013) CASTRO, Bettina; ALMEIDA, Juliana; ARANTES, Paula; VALERIO, Rosa; JORGE, Carmen; AMARO JR., Edson; CASTRO, Luiz