IATAGAN ROCHA JOSINO
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article Pancreatic Metastasis from Papillary Thyroid Carcinoma: A Case Report(2020) MACHADO, Andressa A.; LENZ, Luciano; DOMINGUES, Regina B.; LIMA, Gustavo R. A.; JOSINO, Iatagan R.; CORDERO, Martin A. C.; V, Adriana Safatle-Ribeiro; MARTINS, Bruno C.; PENNACCHI, Caterina M. P. S.; GUSMON, Carla C.; PAULO, Gustavo A.; LIMA, Marcelo S.; BABA, Elisa R.; KAWAGUTI, Fabio S.; UEMURA, Ricardo S.; MALUF-FILHO, FauzeIntroduction differentiated thyroid carcinoma presents with distant metastasis in 4% of cases, usually occurring in the lungs, bones and thoracic lymph nodes. Pancreatic involvement is extremely rare, with few cases reported in the literature. Case report A 47-years-old female patient presented abdominal pain. She had a history of papillary thyroid carcinoma surgically resected in 2009. After 10 years, computed tomography revealed hepatic lesions suggestive of secondary involvement and a solid mass in the pancreatic head. Endoscopic ultrasound fine-needle aspiration was performed in a heterogeneous hypoechoic mass located at pancreatic head. Cell block with immunohistochemistry was positive for thyroglobulin, suggesting papillary thyroid carcinoma metastasis. The patient still survives at present, treating metastasis with Cabozantinib. Conclusion endoscopic ultrasound fine-needle aspiration is a minimally invasive and accurate method of sampling lesions of the pancreas. In combination with clinical history and immunohistochemistry, can confirm diagnosis and define management.conferenceObject IMPACT OF RADIOTHERAPY (RT) ON ADVERSE EVENTS OF SELF-EXPANDING METALLIC STENTS (SEMS) IN PATIENTS WITH ESOPHAGEAL CANCER(2020) MACHADO, Andressa A.; MARTINS, Bruno da Costa; LIMA, Gustavo R.; JOSINO, Iatagan; CORONEL, Martin A.; LIMA, Marcelo S. de; SAFATLE-RIBEIRO, Adriana V.; PENNACCHI, Caterina; GUSMON, Carla C.; BABA, Elisa; KAWAGUTI, Fabio S.; LENZ, Luciano H.; UEMURA, Ricardo S.; PAULO, Gustavo A. de; GEIGER, Sebastian N.; SALLUM, Rubens A.; RIBEIRO, Ulysses; MALUF-FILHO, FauzeconferenceObject ESOPHAGORESPIRATORY FISTULAS INDUCED BY SEMS IN THE TREATMENT OF MALIGNANT ESOPHAGEAL STRICTURES(2020) JOSINO, Iatagan R.; MACHADO, Andressa A.; LIMA, Gustavo R.; CORONEL, Martin A.; LIMA, Marcelo S. de; KAWAGUTI, Fabio S.; GUSMON, Carla C.; UEMURA, Ricardo S.; PENNACCHI, Caterina; LENZ, Luciano; SAFATLE-RIBEIRO, Adriana V.; BABA, Elisa; GEIGER, Sebastian N.; PAULO, Gustavo A. de; MARTINS, Bruno da Costa; MALUF-FILHO, FauzeconferenceObject COMPARISON OF COVERED VS. UNCOVERED SELF-EXPANDABLE METAL STENTS FOR PALLIATION OF DISTAL MALIGNANT BILIARY STRICTURES(2020) LIMA, Gustavo R.; MARTINS, Bruno da Costa; CORONEL, Martin A.; JOSINO, Iatagan R.; MACHADO, Andressa A.; KAWAGUTI, Fabio S.; LIMA, Marcelo S. de; PENNACCHI, Caterina; LENZ, Luciano H.; UEMURA, Ricardo S.; PAULO, Gustavo A. de; GUSMON, Carla C.; BABA, Elisa; GEIGER, Sebastian N.; RIBEIRO, Ulysses; SAFATLE-RIBEIRO, Adriana V.; MALUF-FILHO, FauzeconferenceObject DIAGNOSTIC EVALUATION OF CLINICAL COMPLETE RESPONSE BY PROBE-BASED CONFOCAL ENDOMICROSCOPY AFTER NEOADJUVANT CHEMORADIATION FOR LOCALLY ADVANCED RECTAL ADENOCARCINOMA(2020) SAFATLE-RIBEIRO, Adriana V.; MARQUES, Carlos F.; PIRES, Clelma Batista; ARRAES, Livia; MEIRELLES, Luciana; BABA, Elisa R.; MACHADO, Andressa A.; CORONEL, Martin A.; LIMA, Gustavo R.; JOSINO, Iatagan; ARAUJO, Diogo; PELEGRINELLI-ZAIDAN, Evelise; GUSMON, Carla C.; LIMA, Marcelo S. de; PENNACCHI, Caterina; KAWAGUTI, Fabio S.; UEMURA, Ricardo S.; MARTINS, Bruno da Costa; PAULO, Gustavo A. de; LENZ, Luciano; COTTI, Guilherme C.; NAHAS, Caio Sergio R.; NAHAS, Sergio C.; RIBEIRO, Ulysses; MALUF-FILHO, Fauze- Impact of radiotherapy on adverse events of self-expanding metallic stents in patients with esophageal cancer(2023) MACHADO, Andressa A.; MARTINS, Bruno C.; JOSINO, Iatagan R.; CHEN, Andre T. C.; HONG, Carlos B. C.; SANTOS, Alisson L. D. R.; LIMA, Gustavo R. A.; CORDERO, Martin A. C.; V, Adriana Safatle-Ribeiro; PENNACCHI, Caterina; GUSMON, Carla C.; PAULO, Gustavo A.; LENZ, Luciano; LIMA, Marcelo S.; BABA, Elisa R.; KAWAGUTI, Fabio S.; UEMURA, Ricardo S.; SALLUM, Rubens A. A.; JR, Ulysses Ribeiro; MALUF-FILHO, FauzeSelf-expanding metallic stents (SEMS) are considered the treatment of choice for the palliation of dysphagia and fistulas in inoperable esophageal neoplasms. However, the safety of SEMSs in patients who received or who will be submitted to radiotherapy (RT) is uncertain. The study aimed to evaluate the impact of RT on adverse events (AEs) in patients with esophageal cancer with SEMSs. This is a retrospective study conducted at a tertiary cancer hospital from 2009 to 2018. We collected information regarding RT, the histological type of the tumor, the model of SEMSs and AEs after stent placement. Three hundred twenty-three patients with malignant stenosis or fistula were treated with SEMSs. The predominant histological type was squamous cell carcinoma (79.6%). A total of 282 partially covered and 41 fully covered SEMSs were inserted. Of the 323 patients, 182 did not received RT, 118 received RT before SEMS placement and 23 after. Comparing the group that received RT before stent insertion with the group that did not, the first one presented a higher frequency of severe pain (9/118 7.6% vs. 3/182 1.6%; P = 0.02). The group treated with RT after stent placement had a higher risk of global AEs (13/23 56.5% vs. 63/182 34.6%; P = 0.019), ingrowth/overgrowth (6/23 26.1% vs. 21/182 11.5%; P = 0.045) and gastroesophageal reflux (2/23 8.7% vs. 2/182 1.1%; P = 0.034). Treatment with RT before stent placement in patients with inoperable esophageal neoplasm prolongs survival and is associated with an increased risk of severe chest pain. Treatment with RT of patients with an esophageal stent increases the frequency of minor, not life-threatening AEs.