CARLA MAXIMO PRADO
Projetos de Pesquisa
Unidades Organizacionais
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/05 - Laboratório de Poluição Atmosférica Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/05 - Laboratório de Poluição Atmosférica Experimental, Hospital das Clínicas, Faculdade de Medicina
8 resultados
Resultados de Busca
Agora exibindo 1 - 8 de 8
- Alpha-7 nicotinic receptor stimulation reduces airway inflammation in a murine model of asthma(2016) SANTANA, Fernanda Paula Roncon; MIRANDA, Claudia Jeane Claudino de Pontes; PINHEIRO, Nathalia Montouro; PERINI, Adenir; CAPERUTO, Luciana Chagas; TIBERIO, Iolanda de Fatima Lopes Calvo; PRADO, Marco Antonio Maximo; MARTINS, Milton de Arruda; PRADO, Vania Ferreira; PRADO, Carla Maximo
- Effects of VAChT reduction on the time course of lung inflammation in mice with acute lung injury(2016) PINHEIRO, Nathalia; SANTANA, Fernanda; CAPERUTO, Luciana; TIBERIO, Iolanda; PRADO, Vania; PRADO, Marco Antonio; MARTINS, Milton; PRADO, Carla
- The role of monoterpenes derived from essential oils in lung alteration in a model of emphysema(2016) PEREIRA, Ellen; GUERREIRO, Marina; SANTANA, Fernanda; PINHEIRO, Nathalia; CAPELLO, Tabata; LOPES, Fernanda; OLIVO, Clarice; TIBERIO, Iolanda; MARTINS, Milton; LAGO, Joao; PRADO, Carla
conferenceObject Lung inflammation was attenuated by sakuranetin treatment in a model of acute lung injury(2014) MERNAK, Marcia; SANTANA, Fernanda; PINHEIRO, Nathalia; SARAIVA-RAMANHOLO, Beatriz; GRECCO, Simone; TIBERIO, Iolanda; MARTINS, Milton; LAGO, Joao; PRADO, CarlaconferenceObject Essential oils reduced lung inflammation in a model of acute lung injury(2014) GUERREIRO, Marina; MERNAK, Marcia; SANTANA, Fernanda; PINHEIRO, Nathalia; SARAIVA-RAMANHOLO, Beatriz; CAPELLO, Tabata; TIBERIO, Iolanda; MARTINS, Milton; LAGO, Joao; PRADO, Carla- Inflammation and remodeling modulated by anti IL17 in model of lung injury induced by elastase in mice(2019) LEICK, Edna A.; FUKUZAKI, Silvia; RIGHETTI, Renato F.; SANTOS, Tabata M.; CAMARGO, Leandro N.; GARRIDO, Aurelio C.; ARISTOTELES, Luciana R. C. R. B.; SOUZA, Flavia C. R.; SARAIVA-ROMANHOLO, Beatriz M.; PRADO, Carla M.; MARTINS, Milton A.; TIBERIO, Iolanda F. L. C.
conferenceObject Plant proteinase inhibitor from Enterolobium contortisiliquum (EcTI) attenuates elastase-induced pulmonary inflammatory, remodeling and mechanical alterations in mice(2012) THEODORO-JUNIOR, Osmar A.; MARQUES, Ricardo Henrique; ALMEIDA-REIS, Rafael; MARTINS-OLIVEIRA, Bruno T.; OLIVA, Leandro V.; LOPES, Tales; PRADO, Carla M.; OLIVA, Maria L. V.; MARTINS, Milton; TIBERIO, Iolanda F. L. C.- Different Phenotypes in Asthma: Clinical Findings and Experimental Animal Models(2022) LOURENCO, Luiz Otavio; RIBEIRO, Alessandra Mussi; LOPES, Fernanda Degobbi Tenorio Quirino Dos Santos; TIBERIO, Iolanda de Fatima Lopes Calvo; TAVARES-DE-LIMA, Wothan; PRADO, Carla MaximoAsthma is a respiratory allergic disease presenting a high prevalence worldwide, and it is responsible for several complications throughout life, including death. Fortunately, asthma is no longer recognized as a unique manifestation but as a very heterogenic manifestation. Its phenotypes and endotypes are known, respectively, as pathologic and molecular features that might not be directly associated with each other. The increasing number of studies covering this issue has brought significant insights and knowledge that are constantly expanding. In this review, we intended to summarize this new information obtained from clinical studies, which not only allowed for the creation of patient clusters by means of personalized medicine and a deeper molecular evaluation, but also created a connection with data obtained from experimental models, especially murine models. We gathered information regarding sensitization and trigger and emphasizing the most relevant phenotypes and endotypes, such as Th2-(high) asthma and Th2-(low) asthma, which included smoking and obesity-related asthma and mixed and paucigranulocytic asthma, not only in physiopathology and the clinic but also in how these phenotypes can be determined with relative similarity using murine models. We also further investigated how clinical studies have been treating patients using newly developed drugs focusing on specific biomarkers that are more relevant according to the patient's clinical manifestation of the disease.