ALEXANDRE JACK DWAN
Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
1 resultados
Resultados de Busca
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- Delayed Brain Cyst Formation After Gamma Knife Anterior Capsulotomv(2021) KASABKOJIAN, Stephanie Toscano; DWAN, Alexandre Jack; MAZIERO, Maria Paula; SALLES, Antonio de; GORGULHO, Alessandra; MIGUEL, Euripedes Constantino; VATTIMO, Edoardo Fillipo de Queiroz; LOPES, Antonio CarlosBACKGROUND: Gamma Knife ventral anterior capsulotomy is an effective option to treat refractory obsessive-compulsive disorder. Although well tolerated, complications can develop years after radiosurgery. We describe a case in which abnormal complications induced by very high doses of radiation evolved. CASE DESCRIPTION: A 55-year-old man with refractory obsessive compulsive disorder was treated with Gamma Knife ventral anterior capsulotomy using a dose of 180 Gy. His obsessive-compulsive symptoms improved, but his condition evolved with a manic episode, cognitive memory changes, visual hallucinations, confabulation, and frontal lobe symptoms. Magnetic resonance imaging showed brain edema in the left hemisphere and a 6-mm brain cyst in the right hemisphere at postoperative month 20. CONCLUSIONS: This case shows the consequences of affecting more fibers related to the anterior frontal region than intended with a radiosurgical procedure and illustrates the importance of careful clinical and imaging follow-up after Gamma Knife ventral anterior capsulotomy.