MARCELLO MENTA SIMONSEN NICO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Dermatologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/06 - Laboratório de Imunopatologia da Esquistossomose e outras Parasitoses, Hospital das Clínicas, Faculdade de Medicina
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/06 - Laboratório de Imunopatologia da Esquistossomose e outras Parasitoses, Hospital das Clínicas, Faculdade de Medicina
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bookPart Urtica(2019) WU, Isabelle I. Hue; NICO, Marcello Menta Simonsen- Nail Apparatus Melanoma: Experience of 10 Years in a Single Institution(2019) LEE, Desiree Ji Re; ARBACHE, Samia Trigo; QUARESMA, Maria Victoria; NICO, Marcello Menta Simonsen; GABBI, Tatiana Villas BoasBackground: Nail apparatus melanoma (NAM) is rare. The higher mortality reported in the literature is most likely due to advanced disease associated with delayed diagnosis and treatment. Objective: All patients diagnosed with NAM were followed at a single reference center during a period of 10 years, with emphasis on dermatological and histological findings. Clinical outcomes were included. Methods: A retrospective review of medical records, photographs, and histopathological examination. Results: 73.7% of the patients were female and their mean age was 47 years. Caucasian and African-American patients had a similar incidence (47.4%). There was only 1 Asian patient in this study (5.3%). All patients presented with nail plate pigmentation. The mean prediagnosis duration was 33 months. A total of 63.2% patients had in situ melanoma and an average Breslow index of 2.18 mm in invasive cases. Fifteen patients underwent conservative surgery and 3 underwent phalanx amputation. All patients survived, and 4 have had more than a 5-year follow-up. Conclusion: In situ lesions showed longitudinal bands or total melanonychia with no nail dystrophy. Invasive cases presented with dystrophic lesions (longitudinal splitting of the nail). Conservative surgery provides a good option without worsening the prognosis. All dermatologists should be aware of early signs of NAM, since prognosis depends on early treatment.
bookPart Afecções das mucosas(2019) WU, Isabelle I. Hue; FERREIRA, Paula Silva; SANTI, Claudia Giuli; NICO, Marcello Menta Simonsen- Aphtha Major Perianalis(2019) GUIMARAES, Ana Lucia Monteiro; LOURENCO, Silvia Vanessa; NICO, Marcello Menta Simonsen
bookPart Farmacodermias(2019) GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta SimonsenbookPart Afecções psicogênicas(2019) WU, Isabelle I. Hue; NICO, Marcello Menta Simonsen- Ointment Pseudo-Cheilitis: A Disease Distinct From Factitial Cheilitis. A Series of 13 Patients From Sao Paulo, Brazil(2019) NICO, Marcello Menta Simonsen; DWAN, Alexandre Jack; LOURENCO, Silvia VanessaBackground: The terms exfoliative cheilitis, factitial cheilitis, and morsicatio labiorum are used to describe self-inflicted lesions of the lip. Objective: Here we report and analyze clinical, pathological, and therapeutic data on 13 patients with a form of factitial cheilitis that we believe should be considered a separate entity. Results: Eight patients were male and 5 patients were female. All patients reported pain and presented with crusts consisting of dried saliva and topical medications adherent to the surface of the lips. These patients expressed great concern with their condition, and reported several previous, ineffective treatments. Simple reassurance only was not effective; saline compresses alleviated symptoms for a few patients. Most patients were lost to follow-up. Biopsies were not performed on all patients. Conclusion: This particular type of cheilitis artefacta has been previously described, but some features described herein are new and allow a specific approach: patient's behavior, the ""protrusion sign,"" and possible improvement with antidepressants. For these cases, we propose the term ointment pseudo-cheilitis because it comprises the nature of the attached material and the lack of true inflammation. Further psychiatric characterization is a logical next step in further characterizing this difficult-to-treat condition.
bookPart Dermatoses agudas(2019) PINCELLI, Marcella Soares; GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta Simonsen- CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion(2019) SANDOVAL, Karina Romero; MACHADO, Maria Cecilia Rivitti; OLIVEIRA, Zilda Najjar Prado de; NICO, Marcello Menta SimonsenCHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastatin, with complete clearance of her CHILD nevus. The changes in skin lipid metabolism that explain the CHILD ichthyosiform nevus and their correction through topical application of cholesterol and lovastatin are discussed.
- Nevus Trichilemmo-cysticus: A Mild Case(2019) SANCHEZ, Paula Cristina Faria; VALENTE, Neusa Yuriko Sakai; NICO, Marcello Menta Simonsen