SERGIO BRASIL TUFIK
Projetos de Pesquisa
Unidades Organizacionais
28 resultados
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Agora exibindo 1 - 10 de 28
- Do sleep disorders play a role in pre-eclampsia?(2014) TUFIK, S. B.; BERRO, L. F.; ANDERSEN, M. L.; TUFIK, S.
- Re: Safety and Efficacy of Testosterone Replacement Therapy in Adolescents with Klinefelter Syndrome Reply(2014) TUFIK, Sergio B.; BERRO, Lais F.; ANDERSEN, Monica L.; TUFIK, Sergio
- A systematic review on the role of infrared thermography in the Brown adipose tissue assessment(2020) BRASIL, Sergio; RENCK, Alessandra C.; MENECK, Franciele de; BRIOSCHI, Marcos L.; COSTA, Elaine F.; TEIXEIRA, Manoel J.Brown adipose tissue (BAT) is an endocrine adipose tissue with attributes to dissipate energy as heat in response to changes in temperature and diet. Infrared thermography (IRT) has been studied in recent years in the assessment of BAT thermogenesis, as an option to positron emission tomography - computed tomography (PET-CT), because of several advantages. We performed a systematic review on the use of IRT in BAT assessment. Comprehensive online search was performed in different databases. The QUADAS 2 tool was used to evaluate studies' quality. 12 studies fit the inclusion criteria, whereas only one of these was considered of low risk of bias. 10 studies were favorable to IRT appliance in BAT evaluation, observing elevation of supraclavicular skin temperature correlated with BAT activity. Studies were heterogeneous in design, and a meta-analysis was precluded. Further studies with similar methodologies are needed. Conclusion: Despite the large number of published methodologies, IRT is a promising method for detecting BAT activation. Current knowledge already allows a better understanding of thermography to improve and standardize the technique.
- Estimation of intracranial pressure by ultrasound of the optic nerve sheath in an animal model of intracranial hypertension(2021) JENG, Brasil Chian Ping; ANDRADE, Almir Ferreira de; BRASIL, Sergio; BOR-SENG-SHU, Edson; BELON, Alessandro Rodrigo; ROBERTIS, Maira; DE-LIMA-OLIVEIRA, Marcelo; RUBIANO, Andres Mariano; GODOY, Daniel Agustin; TEIXEIRA, Manoel Jacobsen; PAIVA, Wellingson SilvaBackground: Ultrasound of the optic nerve sheath diameter (ONSD) has been used as a non-invasive and cost-effective bedside alternative to invasive intracranial pressure (ICP) monitoring. However, ONSD time-lapse behavior in intracranial hypertension (ICH) and its relief by means of either saline infusion or surgery are still unknown. The objective of this study was to correlate intracranial pressure (ICP) and ultrasonography of the optic nerve sheath (ONS) in an experimental animal model of ICH and deter-mine the interval needed for ONSD to return to baseline levels. Methods: An experimental study was conducted on 30 pigs. ONSD was evaluated by ultrasound at differ-ent ICPs generated by intracranial balloon inflation, saline infusion, and balloon deflation, and measured using an intraventricular catheter. Results: All variables obtained by ONS ultrasonography such as left, right, and average ONSD (AON) were statistically significant to estimate the ICP value. ONSD changed immediately after balloon inflation and returned to baseline after an average delay of 30 min after balloon deflation (p = 0.016). No statistical sig-nificance was observed in the ICP and ONSD values with hypertonic saline infusion. In this swine model, ICP and ONSD showed linear correlation and ICP could be estimated using the formula:-80.5 + 238.2 x AON. Conclusion: In the present study, ultrasound to measure ONSD showed a linear correlation with ICP, although a short delay in returning to baseline levels was observed in the case of sudden ICH relief.
- Better Understanding of Bariatric Surgery Outcomes Through Sleep(2014) TUFIK, Sergio B.; BERRO, Lais F.; ANDERSEN, Monica L.; TUFIK, Sergio
conferenceObject The Lausanne NoSAS score: a simple and reliable screening tool for sleep apnea(2016) HABA-RUBIO, J.; MARTI-SOLER, H.; HIROTSU, C.; TOBBACK, N.; TUFIK, S. B.; TUFIK, S.; TAFTI, M.; BITTENCOURT, L.; HEINZER, R.- Brain Death Diagnostic Security is Over Organ Donation(2021) BRASIL, Sergio
conferenceObject INTRACRANIAL COMPLIANCE CONCEPTS AND ASSESSMENT OF TRAUMATIC BRAIN INJURY: A SCOPING REVIEW(2022) ZAMBETTA, Rafaella Mendes; OCAMOTO, Gabriela Nagai; FRIGIERI, Gustavo; HAYASHI, Cintya Yukie; BRASIL, Sergio; RABELO, Nicollas Nunes; RUSSO, Thiago Luiz- Assessing ultrasonographic optic nerve sheath diameter in animal model with anesthesia regimens(2022) AZEVEDO, Maira de Robertis; DE-LIMA-OLIVEIRA, Marcelo; BELON, Alessandro Rodrigo; BRASIL, Sergio; TEIXEIRA, Manoel Jacobsen; PAIVA, Wellingson Silva; BOR-SENG-SHU, EdsonPurpose: To determine the normal optical nerve sheath (ONS) diameter ultrasonography (ONSUS) and evaluate the possible effects of drugs on ONS diameter during anesthetic induction in healthy pigs. Methods: Healthy piglets were divided into three groups: a control group, that received xylazine and ketamine (X/K); other that received xylazine, ketamine and propofol (X/K/P); and a third group that received xylazine, ketamine, and thiopental (X/K/T). The sheath diameter was assessed by ultrasonography calculating the average of three measurements of each eye from the left and right sides. Results: 118 animals were anesthetized (49 X/K 33 X/K/P and 39 X/K/T). Mean ONS sizes on both sides in each group were 0.394 +/- 0.048 (X/K), 0.407 +/- 0.029 (X/K/P) and 0.378 +/- 0.042 cm (X/K/T) (medians of 0.400, 0.405 and 0.389, respectively). The ONS diameter varied from 0.287-0.512 cm (mean of 0.302 +/- 0.039 cm). For group X/K, the mean diameter was 0.394 +/- 0.048 cm. Significant differences in ONS sizes between the groups P and T (X/K/P > X/K/T, p = 0.003) were found. No statistically significant differences were detected when other groups were compared (X/K = X/K/P, p = 0.302; X/K = X/K/T, p = 0.294). Conclusion: Sedation with thiopental lead to significative ONS diameter reduction in comparison with propofol. ONSUS may be useful to evaluate responses to thiopental administration.
- A Novel Noninvasive Technique for Intracranial Pressure Waveform Monitoring in Critical Care(2021) BRASIL, Sergio; SOLLA, Davi Jorge Fontoura; NOGUEIRA, Ricardo de Carvalho; TEIXEIRA, Manoel Jacobsen; MALBOUISSON, Luiz Marcelo Sa; PAIVA, Wellingson da SilvaBackground: We validated a new noninvasive tool (B4C) to assess intracranial pressure waveform (ICPW) morphology in a set of neurocritical patients, correlating the data with ICPW obtained from invasive catheter monitoring. Materials and Methods: Patients undergoing invasive intracranial pressure (ICP) monitoring were consecutively evaluated using the B4C sensor. Ultrasound-guided manual internal jugular vein (IJV) compression was performed to elevate ICP from the baseline. ICP values, amplitudes, and time intervals (P2/P1 ratio and time-to-peak [TTP]) between the ICP and B4C waveform peaks were analyzed. Results: Among 41 patients, the main causes for ICP monitoring included traumatic brain injury, subarachnoid hemorrhage, and stroke. Bland-Altman's plot indicated agreement between the ICPW parameters obtained using both techniques. The strongest Pearson's correlation for P2/P1 and TTP was observed among patients with no cranial damage (r = 0.72 and 0.85, respectively) to the detriment of those who have undergone craniotomies or craniectomies. P2/P1 values of 1 were equivalent between the two techniques (area under the receiver operator curve [AUROC], 0.9) whereas B4C cut-off 1.2 was predictive of intracranial hypertension (AUROC 0.9, p < 000.1 for ICP > 20 mmHg). Conclusion: B4C provided biometric amplitude ratios correlated with ICPW variation morphology and is useful for noninvasive critical care monitoring.
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