MATEUS PEREIRA FUNARI
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/35 - Laboratório de Nutrição e Cirurgia Metabólica do Aparelho Digestivo, Hospital das Clínicas, Faculdade de Medicina
LIM/35 - Laboratório de Nutrição e Cirurgia Metabólica do Aparelho Digestivo, Hospital das Clínicas, Faculdade de Medicina
10 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 10
- EUS VERSUS ERCP FOR PRIMARY DRAINAGE OF MALIGNANT BILIARY OBSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS BASED ON RANDOMIZED TRIALS(2019) LOGIUDICE, Fernanda P.; BERNARDO, Wanderlei M.; GALETTI, Facundo; FUNARI, Mateus P.; SAGAE, Vitor M.; MATSUBAYASHI, Carolina O.; BRUNALDI, Vitor O.; MATUGUMA, Sergio E.; CHENG, Spencer; MOURA, Eduardo G. de
- Endoscopic stag beetle knife treatment for symptomatic Zenker's diverticulum(2021) MONTE, Epifanio Silvino do; IDE, Edson; SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; FUNARI, Mateus Pereira; OLIVEIRA, Pedro Victor Aniz Gomes de; MOURA, Eduardo Guimaraes Hourneaux de
- ADVERSE EVENTS ASSOCIATED WITH DIFFERENT MODES OF ELECTRICAL CURRENT USED IN BILIARY SPHINCTEROTOMY: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS(2019) FUNARI, Mateus P.; BERNARDO, Wanderlei M.; GALETTI, Facundo; SAGAE, Vitor M.; LOGIUDICE, Fernanda P.; MATSUBAYASHI, Carolina O.; BRUNALDI, Vitor O.; IDE, Edson; MOURA, Diogo T. de; MOURA, Eduardo G. de
- Endoscopic submucosal dissection versus transanal endoscopic surgery for the treatment of early rectal tumor: a systematic review and meta-analysis(2020) SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; MOURA, Diogo Turiani Hourneaux de; BRUNALDI, Vitor Ottoboni; LOGIUDICE, Fernanda Prado; FUNARI, Mateus Pereira; BABA, Elisa Ryoka; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux deBackground Minimally invasive treatment of early-stage rectal lesion has presented good results, with lower morbidity than surgical resection. Transanal endoscopic microsurgery (TEM) and transanal minimally invasive surgery (TAMIS) are the main methods of transanal surgery. However, endoscopic submucosal dissection (ESD) has been gaining ground because it allows en bloc resections with low recurrence rates. The aim of this study was to analyze ESD in comparison with transanal endoscopic surgery. Methods We searched MEDLINE, EMBASE, SciELO, Cochrane CENTRAL, and Lilacs/Bireme with no restrictions on the date or language of publication. The outcomes evaluated were recurrence rate, complete (R0) resection rate, en bloc resection rate, length of hospital stay, duration of the procedure, and complication rate. Results Six retrospective cohort studies involving a collective total of 326 patients-191 in the ESD group and 135 in the transanal endoscopic surgery group were conducted. There were no statistically significant differences between the groups for any of the outcomes evaluated. Conclusions For the minimally invasive treatment of early rectal tumor, ESD and surgical techniques do not differ in terms of local recurrence, en bloc resection rate, R0 resection rate, duration of the procedure, length of hospital stay, or complication rate, however, evidence is very low.
- Endoscopic treatment of gastric antral vascular ectasia(2022) HIRSCH, Bruno Salomao; RIBEIRO, Igor Braga; FUNARI, Mateus Pereira; SAGAE, Vitor Massaro Takamatsu; MANCINI, Fabio Catache; OLIVEIRA, Guilherme Henrique Peixoto de; MOURA, Eduardo Guimaraes Hourneaux de; BERNARDO, Wanderley MarquesThe Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field, to standardize how to conduct, and to assist in the reasoning and decision-making of doctors. The information provided by this project must be critically evaluated by the physician responsible for the conduct that will be adopted depending on the conditions and the clinical condition of each patient.
- Endoscopic biliary sphincterotomy: electric current mode(2022) FUNARI, Mateus Pereira; SAGAE, Vitor Massaro Takamatsu; MOURA, Eduardo Guimaraes Hourneaux de; BERNARDO, Wanderley MarquesINTRODUCTION Endoscopic retrograde cholangiopancreatography (ERCP) asso-ciated with biliary sphincterotomy is a procedure performed widely in medical practice. However, this intervention is not an exempt from complications (4-5%) such as acute pancreatitis, bleeding, perforation, cholangitis, or even death (0.02-0.4%)1-3. Several studies point to the correlation between the electric cur-rent mode (pure cut, blend, pulsed cut, or endocut, and pure cut followed by blend) used in endoscopic sphincterotomy and the inci-dence of adverse events4-6. A better knowledge of the subject based on evidence can assist us in making the best decision in clinical practice. Our objective is, through a systematic review and meta -anal-ysis, to trace the safety profile of each modality of electric cur-rent (pure cut, pulsed cut, blend cut, and pure cut followed by blend) employed in endoscopic biliary sphincterotomy to reduce the incidence of adverse events related to this procedure. METHODS A systematic review and meta-analysis of the literature (Medline, Central Cochrane, Embase, LILACS VHL, and grey litera-ture) were carried out according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) recommendations7. We used the PICO system (Patient: older than 18 years with the indication of ERCP and biliary sphinc-terotomy; Intervention and Control: respective modalities of electric current; and Outcome: adverse events such as acute pancreatitis, bleeding, perforation, and cholangitis). We selected only randomized controlled trials that included patients aged more than 18 years who underwent ERCP with biliary sphincterotomy for various causes (e.g., choledocholithiasis, obstructive neoplasia, benign strictures, and biliary fistulas) random-ized to any of the modalities of electric current under evaluation. The risk of bias in each study was assessed using the Cochrane bias risk tool8. The level of evidence for each outcome was eval-uated according to GRADE (Grading of Recommendations Assessment, Development and Evaluation)9. The data were meta-analyzed using the RevMan 5.3 soft-ware, and the results were revealed as forest plots. RESULTS After removing duplicates, 12,282 articles were screened, including 10 randomized clinical trials in our study4,10-18. Annex Figure 1 summarizes the selection process. The risk of bias in the included studies is expressed in Annex Table 1. The characteristics of the studies and results are presented in Chart 1. Results expressed by comparison:
- Endoscopic approach to complex gastric tube stricture after laparoscopic sleeve gastroplasty: a case report(2021) FUNARI, Mateus Pereira; MIRANDA NETO, Antonio Afonso; SAGAE, Vitor Massaro Takamatsu; SOUZA, Thiago Ferreira de; MINATA, Mauricio Kazuyoshi; CHENG, Spencer; MOURA, Eduardo Guimaraes Hourneaux de
- ENDOSCOPIC SUBMUCOSAL DISSECTION VERSUS TRANSANAL ENDOSCOPIC SURGERY FOR EARLY RECTAL CANCER - A SYSTEMATIC REVIEW AND META-ANALISYS OF COMPARATIVE STUDIES(2019) SAGAE, Vitor M.; BERNARDO, Wanderlei M.; GALETTI, Facundo; FUNARI, Mateus P.; LOGIUDICE, Fernanda P.; MATSUBAYASHI, Carolina O.; BRUNALDI, Vitor O.; MIYAJIMA, Nelson T.; MOURA, Diogo T. de; MOURA, Eduardo G. de
- EUS-guided gastroenterostomy versus duodenal stent placement and surgical gastrojejunostomy for the palliation of malignant gastric outlet obstruction: a systematic review and meta-analysis(2021) BOGHOSSIAN, Mateus Bond; FUNARI, Mateus Pereira; MOURA, Diogo Turiani Hourneaux De; MCCARTY, Thomas R.; SAGAE, Vitor Massaro Takamatsu; I, Yen- Chen; MENDIETA, Pastor Joaquin Ortiz; PONTE NETO, Fernando Lopes; BERNARDO, Wanderley Marques; SANTOS, Marcos Eduardo Lera dos; CHAVES, Filipe Tomishige; KHASHAB, Mouen A.; MOURA, Eduardo Guimaraes Hourneaux dePurpose Malignant gastric outlet obstruction (GOO) is associated with significant morbidity and decreased quality of life, thereby necessitating effective and safe palliative treatment. As such, we sought to compare endoscopic ultrasound-guided gastroenterostomy (EUS-GE) versus duodenal stent (DS) placement and surgical gastrojejunostomy (SGJ) for palliation of malignant GOO. Methods Searches of electronic databases were performed to identify studies comparing EUS-GE versus DS and/or SGJ for palliative treatment of GOO. Outcomes included technical and clinical success, severe adverse events (SAEs), rate of stent obstruction (including tumor ingrowth), length of hospital stay (LOS), reintervention, and 30-day all-cause mortality. Differences in dichotomous and continuous outcomes were reported as risk difference and mean difference, respectively. Results Seven studies (n = 513 patients) were included. When compared to DS placement, EUS-GE was associated with a higher clinical success, fewer SAEs, decreased stent obstruction, lower rate of tumor ingrowth, and decreased need for reintervention. Compared to SGJ, EUS-GE was associated with a lower technical success; however, LOS was significantly decreased. All other outcomes including clinical success, SAEs, reintervention rate, and 30-day mortality were not significantly different between an EUS-guided versus surgical approach. Conclusions EUS-GE was associated with significantly improved outcomes compared to DS placement for palliative treatment of malignant GOO. Despite SGJ possessing a higher technical success compared to EUS-GE, LOS was significantly longer with no difference in clinical success or rate of adverse events.
- Metabolic Effects of Endoscopic Duodenal Mucosal Resurfacing: a Systematic Review and Meta-analysis(2021) OLIVEIRA, Guilherme Henrique Peixoto de; MOURA, Diogo Turiani Hourneaux de; FUNARI, Mateus Pereira; MCCARTY, Thomas R.; RIBEIRO, Igor Braga; BERNARDO, Wanderley Marques; SAGAE, Vitor Massaro Takamatsu; FREITAS JR., Joao Remi; SOUZA, Gabriel Mayo de Vieira; MOURA, Eduardo Guimaraes Hourneaux deDuodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.