ROSA MARIA RODRIGUES PEREIRA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Clínica Médica, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
19 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 19
conferenceObject Performance of FRAX® Brazil and NOGG Methodology with and Without Bone Mineral Density upon Predicting Fractures on a Community-Dwelling Elderly Population with High Incidence of Osteoporotic Fractures - The Sao Paulo Ageing and Health (SPAH) Study(2023) FREITAS, Thiago Q.; OLALLA, Leonardo F. Guerron; TAKAYAMA, Liliam; CAPARBO, Valeria F.; FIGUEIREDO, Camille P.; MACHADO, Luana G.; DOMICIANO, Diogo S.; PEREIRA, Rosa M. R.conferenceObject Association between Metabolic Syndrome and Bone Mineral Density in a Community-dwelling Older Women: the Sao Paulo Ageing & Health Study (SPAH)(2013) MACHADO, Luana; DOMICIANO, Diogo; LOPES, Jaqueline; FIGUEIREDO, Camille; CAPARBO, Valeria; TAKAYAMA, Liliam; PEREIRA, RosaconferenceObject Healing of Tumor-Induced Osteomalacia as Assessed by HR-pQCT is Not Similar Across the Peripheral Skeletal Sites in the First Years Following Complete Tumor Excision(2023) ROSA NETO, Nilton Salles; PEREIRA, Rosa Maria; YUKI, Emily Figueiredo Neves; SOUZA, Fernando Henrique Carlos de; TAKAYAMA, Liliam; ISHY, Augusto; CARNEIRO, Maria Inez da Silveira; LIMA, Luiz Guilherme Cernaglia Aureliano de; ELIAS, Alexandre Jose ReisconferenceObject Chronic Kidney Disease-Associated Frailty is characterized by changes in Muscular Expression of RANKL and FNDC5, which are partially reverted after Parathyroidectomy(2023) DUQUE, Eduardo J.; CRISPILHO, Shirley; OLIVEIRA, Ivone B.; REIS, Luciene M. dos; FURUKAWA, Luzia; TAKAYAMA, Liliam; PEREIRA, Rosa M.; SHINJO, Samuel K.; AVESANI, Carla; JORGETTI, Vanda; ELIAS, Rosilene M.; MOYSES, Rosa M.conferenceObject High prevalence of vitamin D insufficiency in older community people: the role of season, diabetes, parathormone, female gender and age. The Sao Paulo Ageing & Healthy Study (SPAH)(2013) FIGUEIREDO, Camille; LOPES, Jaqueline; FERNANDES, Georgea; TAKAYAMA, Liliam; CAPARBO, Valeria; PEREIRA, RosaconferenceObject Bone histomorphometric effects of HIV infection and Antiretroviral therapy(2018) RAMALHO, Janaina; MARTINS, Csw; PEREIRA, Rmr; NICKOLAS, Thomas; YIN, Mt; GALVAO, J.; EIRA, Margareth; REIS, Lm; FURUKAWA, Luzia; JORGETTI, Vanda; MOYSES, RmconferenceObject Evaluation of Cortical Microarchitecture and Biomechanical Properties 6-12 Months after Atypical Femoral Fracture(2019) PEREZ, Mariana; DOMICIANO, Diego; PEREIRA, Rosa; JORGETTI, VandaconferenceObject Incidence and Risk Factors for Osteoporotic Non-vertebral Fracture in Low-Income Community-dwelling Elderly: a Population-based Prospective Cohort Study in Brazil. The Sao Paulo Ageing & Health (SPAH) Study.(2020) DOMICIANO, Diogo Souza; MACHADO, Luana Gergeim; FIGUEIREDO, Camille Pinto; CAPARBO, Valeria; OLIVEIRA, Ricardo M.; MENEZES, Paulo Rossi; PEREIRA, Rosa Maria Rodrigues- Treatment of Human Immunodeficiency Virus Infection With Tenofovir Disoproxil Fumarate-Containing Antiretrovirals Maintains Low Bone Formation Rate, But Increases Osteoid Volume on Bone Histomorphometry(2019) RAMALHO, Janaina; MARTINS, Carolina Steller Wagner; GALVAO, Juliana; FURUKAWA, Luzia N.; DOMINGUES, Wagner V.; OLIVEIRA, Ivone B.; REIS, Luciene M. dos; PEREIRA, Rosa M. R.; NICKOLAS, Thomas L.; YIN, Michael T.; EIRA, Margareth; JORGETTI, Vanda; MOYSES, Rosa M. A.Bone mineral density (BMD) loss is a known complication of human immunodeficiency virus (HIV) infection and its treatment, particularly with tenofovir disoproxil fumarate (TDF)-containing antiretroviral regimens. Although renal proximal tubular dysfunction and phosphaturia is common with TDF, it is unknown whether BMD loss results from inadequate mineralization. We evaluated change in BMD by dual-energy X-ray absorptiometry (DXA) and bone histomorphometry by tetracycline double-labeled transiliac crest biopsies in young men living with HIV before (n = 20) and 12 months after (n = 16) initiating TDF/lamivudine/efavirenz. We examined relationships between calciotropic hormones, urinary phosphate excretion, pro-inflammatory and pro-resorptive cytokines, and bone remodeling-related proteins with changes in BMD and histomorphometry. Mean age was 29.6 +/- 5.5 years, with mean CD4 + T cell count of 473 +/- 196 cells/mm(3). At baseline, decreased bone formation rate and increased mineralization lag time were identified in 16 (80%) and 12 (60%) patients, respectively. After 12 months, we detected a 2% to 3% decrease in lumbar spine and hip BMD by DXA. By histomorphometry, we observed no change in bone volume/total volume (BV/TV) and trabecular parameters, but rather, increases in cortical thickness, osteoid volume, and osteoblast and osteoclast surfaces. We did not observe significant worsening of renal phosphate excretion or mineralization parameters. Increases in PTH correlated with decreased BMD but not histomorphometric parameters. Overall, these data suggest abnormalities in bone formation and mineralization occur with HIV infection and are evident at early stages. With TDF-containing antiretroviral therapy (ART), there is an increase in bone remodeling, reflected by increased osteoblast and osteoclast surfaces, but a persistence in mineralization defect, resulting in increased osteoid volume. (c) 2019 American Society for Bone and Mineral Research
conferenceObject Elucidating the crosstalk among lncRNAs, microRNAs and mRNAs in the bone metabolism related genes associated with Coronary Vascular Calcification in elderly women cohort of the Sao Paulo Aging and Health Study(2019) WICIK, Zofia; NETO, Levi H. Jales; TAKAYAMA, Liliam; CAPARBO, Valeria F.; FERNANDES, Georgea H.; PEREIRA, Rosa M. R.; LOPES, Neuza; GUZMAN, Luis F. E.; PEREIRA, Alexandre C.