MARCO DE TUBINO SCANAVINO

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Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina

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  • article 8 Citação(ões) na Scopus
    The eleven-item Alcohol, Smoking and Substance Involvement Screening Test (ASSIST-11): Cross-cultural psychometric evaluation across 42 countries
    (2023) LEE, Chih-Ting; LIN, Chung-Ying; KOOS, Monika; NAGY, Lena; KRAUS, Shane W.; DEMETROVICS, Zsolt; POTENZA, Marc N.; BALLESTER-ARNAL, Rafael; BATTHYANY, Dominik; BERGERON, Sophie; BILLIEUX, Joel; BURKAUSKAS, Julius; CARDENAS-LOPEZ, Georgina; CARVALHO, Joana; CASTRO-CALVO, Jesus; CHEN, Lijun; CIOCCA, Giacomo; CORAZZA, Ornella; CSAKO, Rita I.; FERNANDEZ, David P.; FERNANDEZ, Elaine F.; FUJIWARA, Hironobu; FUSS, Johannes; GABRHELIK, Roman; GEWIRTZ-MEYDAN, Ateret; GJONESKA, Biljana; GOLA, Mateusz; GRUBBS, Joshua B.; HASHIM, Hashim T.; ISLAM, Md. Saiful; ISMAIL, Mustafa; JIMENEZ-MARTINEZ, Martha; JURIN, Tanja; KALINA, Ondrej; KLEIN, Verena; KOLTO, Andras; LEE, Sang-Kyu; LEWCZUK, Karol; LOCHNER, Christine; LOPEZ-ALVARADO, Silvia; LUKAVSKA, Katerina; MAYTA-TRISTAN, Percy; MILEA, Ionut; MILLER, Dan J.; OROSOVA, Olga; OROSZ, Gabor; TEAM, Fernando P. Sungkyunkwan Univ Res; PONCE, Fernando P.; QUINTANA, Gonzalo R.; GARZOLA, Gabriel C. Quintero; RAMOS-DIAZ, Jano; RIGAUD, Kevin; ROUSSEAU, Ann; SCANAVINO, Marco De Tubino; SCHULMEYER, Marion K.; SHARAN, Pratap; SHIBATA, Mami; SHOIB, Sheikh; SIGRE-LEIROS, Vera; SNIEWSKI, Luke; SPASOVSKI, Ognen; STEIBLIENE, Vesta; STEIN, Dan J.; STRIZEK, Julian; UNSAL, Berk C.; VAILLANCOURT-MOREL, Marie-Pier; HOUT, Marie Claire Van; BOTHE, Beata
    The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) is an instrument to screen substance -use-related health risks. However, little is known whether the ASSIST could be further shortened while remaining psychometrically sound across different countries, languages, gender identities, and sexual-orientation-based groups. The study aimed to validate a shortened 11-item ASSIST (ASSIST-11). Using the International Sex Sur-vey data, 82,243 participants (M age = 32.39 years) across 42 countries and 26 languages completed questions from the ASSIST-11 regarding gender identity, sexual orientation, and other information. Confirmatory factor analysis (CFA) and multigroup CFA (MGCFA) evaluated the ASSIST-11's structure and tested measurement invariance across groups. Cronbach's & alpha; and McDonald's & omega; were used to examine the internal consistency. Cohen's d and independent t-tests were used to examine known-group validity. The ASSIST-11 was unidimen-sional across countries, languages, age groups, gender identities (i.e., men, women, and gender-diverse in-dividuals), and sexual orientations (i.e., heterosexual and sexual minority individuals). Cronbach's & alpha; was 0.63 and McDonald's & omega; was 0.68 for the ASSIST-11. Known-group validity was supported by Cohen's d (range be-tween 0.23 and 0.40) with significant differences (p-values<0.001). The ASSIST-11 is a modified instrument with a unidimensional factor structure across different languages, age groups, countries, gender identities, and sexual orientations. The low internal consistency of the ASSIST-11 might be acceptable as it assesses a broad concept (i. e., use of several different substances). Healthcare providers and researchers may use the ASSIST-11 to quickly assess substance-use information from general populations and evaluate the need to follow up with more detailed questions about substance use.
  • article 8 Citação(ões) na Scopus
    Sleep quality in overweight pregnant women
    (2015) RIBEIRO, Meireluci Costa; NAKAMURA, Mary Uchiyama; TORLONI, Maria Regina; SCANAVINO, Marco De Tubino; FORTE, Bruna Maria Bernardi; MANCINI, Pedro Eduardo; MATTAR, Rosiane
    PURPOSE: To compare sleep quality of overweight versus normal weight women in the second and third trimesters of pregnancy. METHODS: A cross-sectional study involving 223 women with 14 or more weeks of pregnancy, 105 of them overweight (pre-pregnancy body mass index - BMI - >= 25.0 kg/m(2)) and 118 of normal weight (BMI 18.5-24.9 kg/m2), attending the prenatal care clinic. The Brazilian version of the Pittsburgh Sleep Quality Index (PSQI-BR) questionnaire was used to evaluate sleep quality. The Student t-test and the chi-square test were used to compare differences between groups and a p value < 0.05 was considered statistically significant. RESULTS: Most of the participants (67.7%) were poor sleepers (total score > 5); this proportion was significantly higher among overweight (80/105) versus normal weight (67/118) women (76.2 versus 56.8%, p= 0,004). During the second trimester, this difference did not reach statistical significance (72.5 versus 53.7%, respectively, p= 0.06) but mean total PSQI-BR scores were significantly higher among overweight participants (7.0 +/- 3.8 versus 5.5 +/- 3.2, p= 0.02). In the 2nd trimester, overweight women also had higher scores for sleep latency (1.4 +/- 1.0 versus 1.0 +/- 0.9, p= 0.02) and subjective sleep quality (1.3 +/- 0.8 versus 0.8 +/- 0.8, p= 0.02). In the third trimester, the proportion of women with poor sleep quality was significantly higher in the overweight group, but did not reach statistical significance (79.6 versus 60.8%, p= 0.06). During this period, total mean scores were similar for women with and without excess weight (9.4 +/- 4.2 versus 8.3 +/- 4.6, p= 0.2). However, overweight women had higher mean scores for sleep disturbance (2.3 +/- 0.7 versus 2.0 +/- 0.8, p= 0.04). CONCLUSION: Overweight women had a poorer sleep quality than normal weight women in the second and third trimesters of pregnancy.
  • article 44 Citação(ões) na Scopus
    Compulsive sexual behavior and psychopathology among treatment-seeking men in Sao Paulo, Brazil
    (2013) SCANAVINO, Marco de Tubino; VENTUNEAC, Ana; ABDO, Carmita Helena Najjar; TAVARES, Hermano; AMARAL, Maria Luiza Sant'Ana do; MESSINA, Bruna; REIS, Sirlene Caramello dos; MATTINS, Joao Paulo Lian Branco; PARSONS, Jeffrey T.
    This study examined compulsive sexual behavior (CSB) and psychopathology in a treatment-seeking sample of men in Sao Paulo, Brazil. Eighty-six men (26% gay, 17% bisexual, 57% heterosexual) who met diagnostic criteria for excessive sexual drive and sexual addiction completed assessments consisting of the Mini International Neuropsychiatric Interview, a structured clinical interview for DSM-IV Axis I Disorders Clinical Version (segment for Impulse Control Disorder), Sexual Compulsivity Scale (SCS), and questions about problematic CSB. The average SCS score for our sample was above the cut-off score reported in other studies, and 72% of the sample presented at least one Axis I psychiatric diagnosis. There were no differences among gay, bisexual, and heterosexual men on SCS scores and psychiatric conditions, but gay and bisexual men were more likely than heterosexual men to report casual sex and sex with multiple casual partners as problematic behaviors. SCS scores were associated with psychiatric co-morbidities, mood disorder, and suicide risk, but diagnosis of a mood disorder predicted higher SCS scores in a regression analysis. The study provides important data on the mental health needs of men with CSB in Sao Paulo, Brazil.
  • article 2 Citação(ões) na Scopus
    Treatment effects and adherence of sexually compulsive men in a randomized controlled trial of psychotherapy and medication
    (2023) SCANAVINO, Marco D. T.; GUIRADO, Alia Garrudo; MARQUES, Joao Miguel; AMARAL, Maria Luiza Sant'Ana Do; MESSINA, Bruna; REIS, Sirlene Caramello Dos; BARROS, Vivian Boschesi; ABDO, Carmita Helena Najjar; TAVARES, Hermano; PARSONS, Jeffrey T.
    Background: Little attention has been given to efficacious treatment and adherence to treatment of compulsive sexual behavior (CSB). Aims: Randomized controlled trial investigated short-term psycho -dynamic group therapy followed by relapse prevention group (STPGP-RPGT) and pharmacological treatment (PT) for CSB men on sexual compulsivity and adherence. Method: 135 men, 38 (SD = 9) years old on average, were randomly assigned to 1) STPGP-RPGT; 2) PT; 3) Both. Participants completed measures at baseline, 25th, and 34th week. 57 (42.2%) participants dropped out between baseline and 25th week, and 68 (50.4%) between baseline and 34th week. 94 (69.6%) did not adhere (80% pills taken or attended 75% therapy sessions). Results: A significant interaction effect was found between time and group (F (4, 128) = 2.62, P = 0.038, ES = 0.08), showing who received PT improved less in sexual compulsivity than those who received STPGP-RPGT (t = 2.41; P = 0.038; ES = 0.60) and PT thorn STPGP-RPGT (t = 3.15; P = 0.007, ES = 0.74). Adherent participants improved more in sexual compulsivity than non-adherent at the 25th week (t = 2.82; P = 0.006, ES = 0.65) and 34th week (t = 2.26; P = 0.027, ES = 0.55), but there was no interaction effect, F (2, 130) = 2.88; P = 0.06; ES = 0.04). The most reported behavior (masturbation) showed greater risk of non-adherence (72.6%). Discussion and conclusions: Adherent participants improved better than non-adherent. Participants who received psychotherapy improved better than those who received PT. Methodological limitations preclude conclusions on efficacy.
  • article 14 Citação(ões) na Scopus
    Maternal overweight and sexual function in pregnancy
    (2016) RIBEIRO, Meireluci C.; NAKAMURA, Mary U.; TORLONI, Maria R.; SCANAVINO, Marco De T.; MANCINI, Pedro E.; FORTE, Bruna M. B.; MATTAR, Rosiane
    IntroductionObesity and overweight are increasing worldwide and may compromise female sexual function. Our aim was to compare the sexual function of normal and overweight women in pregnancy. Material and methodsA cross-sectional study involving 223 pregnant women: 105 overweight [pre-pregnancy body mass index (BMI) 25.0 kg/m(2)] and 118 normal weight (BMI 18.5-24.9 kg/m(2)), in the 2nd and 3rd trimester of pregnancy. These women were managed at an antenatal clinic of a public university hospital in SAo Paulo, Brazil, between 2011 and 2014. The Female Sexual Function Index (FSFI) was used. The characteristics of normal and overweight women were compared using two-tailed Student's t- or chi-squared tests. Differences in mean FSFI scores were assessed using the Kruskal-Wallis test. Pearsons correlation coefficient was used to assess the correlation between pre-pregnancy BMI and FSFI scores. ResultsIn the 2nd trimester, mean total FSFI scores were similar in overweight (n = 51) compared to normal weight (n = 67) women (21.9 9.8 vs. 21.7 +/- 10.4, p = 1.000). In the 3rd trimester, overweight women (n = 54) had significantly lower total FSFI scores than normal weight women (n = 51; 19.1 +/- 10.3 vs. 24.5 +/- 9.7, p = 0.0004). In the 3rd trimester, overweight women also had significantly lower mean scores in desire, arousal, lubrication, orgasm and dyspareunia domains. We found an inverse correlation between pre-pregnancy BMI and mean 3rd trimester total FSFI scores (r = -0.212, p = 0.030), desire (r = -0.216, p = 0.027) and orgasm (r = -0.222, p = 0.023). ConclusionOverweight women in the 3rd trimester of pregnancy had poorer sexual function compared with normal weight women.
  • article 4 Citação(ões) na Scopus
    Sexual Dysfunctions Among People Living With HIV With Long- Term Treatment With Antiretroviral Therapy
    (2022) SCANAVINO, Marco De Tubino; MORI, Emi; NISIDA, Vera Vichr; AVELINO-SILVA, Vivian I.; AMARAL, Maria Luiza Sant'ana do; MESSINA, Bruna; SEGURADO, Aluisio Cotrim
    Introduction: Sexuality plays an essential role in the psychosocial well-being of people living with HIV (PLHIV) but it is still less assessed by healthcare professionals during treatment. Aim: To investigate the frequency of those screening positive for sexual dysfunction (SD) and associated factors according to gender/sexual orientation in PLHIV under long-term treatment with antiretroviral therapy (ART). Methods: Between September 2013 and October 2016, 234 PLHIV adults in treatment in Sao Paulo were included. Participants were sexually active, did not present sexual orientation disorder or body dysmorphicdisor-der, and did not use sexual hormones. We performed clinical interviews and measured levels of depression, anxiety, and levels of sexual hormones. SD was assessed using a self-report questionnaire. Main Outcome Measures: Proportion of participants screening positive for SD in the International Index of Erectile Function, the Index of Premature Ejaculation, and the Female Sexual Function Index. In the regression analyses, the outcome SD considered any SD presented with disregard to gender. Results: 70% of participants reported consistent adherence to ART and 96% had an undetectable viral load. The median (Md) duration of ART was 198 months (inter quartil range, IQR 111.6-230.4) and the median CD4 was 655 cells/mm(3) (IQR 443-871). Screening positive for erectile dysfunction was 49.7%, premature ejaculation 16.9%, female sexual dysfunction 27.4% and hypoactive desire 45.1%. Lower testosterone and prolactin levels were associated with erectile dysfunction in heterosexual men (n = 58); lower levels of oestradiol and higher levels of follicle stimulating hormone were associated with female sexual dysfunction and hypoactive desire in female participants (n = 63). The multivariable model used included comorbidities and hormonal abnormality and found that age (odds ratio, OR = 1.04, 95% confidence interval, 95%CI 1.00-1.08, P = .026) and the presence of depression/anxiety (OR = 2.96; 95%CI 1.52-5.77; P = .001) were associated with SD. Also, men reporting engaging in sex with other men were associated with screening positive for SD (OR 2.66; 95%CI 1.52-5.77, P = .013). During treatment of PLHIV, it is important to evaluate sexual health and symptoms of depression and anxiety specifically. The strength of this study consists in evaluating PLHIV who have been in long-term treatment with ART and analyzing those screening positive for SD and associated factors for each group (heterosexual men, men reporting engaging in sex with other men, and women). Limitation includes the difficulty to generalize the findings of the study, and not exploring women's sexual orientation. Conclusion: PLHIV in long-term treatment with ART presented alarming rates of depression/anxiety which in turn is correlated with sexual and physical health problems.
  • article 1 Citação(ões) na Scopus
    Symptoms of depression (not anxiety) mediate the relationship between childhood sexual abuse and compulsive sexual behaviors in men
    (2023) REIS, Sirlene C.; PARK, Katey E.; DIONNE, Michelle M.; KIM, Hyoun S.; SCANAVINO, Marco D. T.
    Objective: Childhood sexual abuse is associated with compulsive sexual behavior, depression, and anxiety in men. Furthermore, both depression and anxiety have been linked to compulsive sexual behaviors. However, whether anxiety and depression mediate the relationship between childhood sexual abuse and compulsive sexual behaviors has yet to be tested. We investigated whether symptoms of depression and anxiety mediate the relationship between childhood sexual abuse and compulsive sexual behaviors in 222 men seeking treatment for such behaviors. Methods: Participants completed the Sexual Compulsivity Scale, Childhood Trauma Questionnaire, Beck Depression Inventory, and Beck Anxiety Inventory. A cross-sectional parallel mediation analysis was conducted. Results: The prevalence of childhood sexual abuse in our sample was 57%. Significant correlations were found between childhood sexual abuse and compulsive sexual behaviors, depression, and anxiety. The results of the mediation analyses suggested that depression (B = 0.07, standard error [SE] = 0.03, 95%CI 0.02 to 0.15), but not anxiety (B = 0.02, SE = 0.02, 95%CI-0.2 to 0.07), mediated the link between childhood sexual abuse and compulsive sexual behaviors. The pattern of our results remained the same when controlling for other types of childhood trauma. Conclusions: Depression, not anxiety, appears to mediate the relationship between childhood sexual abuse and compulsive sexual behaviors in men. Future research that tests our mediation analyses using a prospective longitudinal study would be highly informative.
  • article 32 Citação(ões) na Scopus
    Sexual Compulsivity Scale, Compulsive Sexual Behavior Inventory, and Hypersexual Disorder Screening Inventory: Translation, Adaptation, and Validation for Use in Brazil
    (2016) SCANAVINO, Marco de T.; VENTUNEAC, Ana; RENDINA, H. Jonathon; ABDO, Carmita H. N.; TAVARES, Hermano; AMARAL, Maria L. S. do; MESSINA, Bruna; REIS, Sirlene C. dos; MARTINS, Joao P. L. B.; GORDON, Marina C.; VIEIRA, Julie C.; PARSONS, Jeffrey T.
    Epidemiological, behavioral, and clinical data on sexual compulsivity in Brazil are very limited. This study sought to adapt and validate the Sexual Compulsivity Scale (SCS), the 22-item version of the Compulsive Sexual Behavior Inventory (CSBI-22), and the Hypersexual Disorder Screening Inventory (HDSI) for use in Brazil. A total of 153 participants underwent psychiatric assessment and completed self-reported measures. The adaptation process of the instruments from English to Portuguese followed the guidelines of the International Society for Pharmacoeconomics and Outcomes Research. The reliability and validity of the HDSI criteria were evaluated and the construct validity of all measures was examined. For the SCS and HDSI, factor analysis revealed one factor for each measure. For the CSBI-22, four factors were retained although we only calculated the scores of two factors (control and violence). All scores had good internal consistency (alpha >.75), presented high temporal stability (>.76), discriminated between patients and controls, and presented strong (rho > .81) correlations with the Sexual Addiction Screening Test (except for the violence domain = .40) and moderate correlations with the Impulsive Sensation Seeking domain of the Zuckerman Kuhlman Personality Questionnaire (rho between .43 and .55). The sensitivity of the HDSI was 71.93 % and the specificity was 100 %. All measures showed very good psychometric properties. The SCS, the HDSI, and the control domain of the CSBI-22 seemed to measure theoretically similar constructs, as they were highly correlated (rho > .85). The findings support the conceptualization of hypersexuality as a cluster of problematic symptoms that are highly consistent across a variety of measures.
  • article 1 Citação(ões) na Scopus
    Psychometric properties of the Alcohol Use Disorders Identification Test (AUDIT) across cross-cultural subgroups, genders, and sexual orientations: Findings from the International Sex Survey (ISS)
    (2023) HORVATH, Zsolt; NAGY, Lena; KOOS, Monika; KRAUS, Shane W.; DEMETROVICS, Zsolt; POTENZA, Marc N.; BALLESTER-ARNAL, Rafael; BATTHYANY, Dominik; BERGERON, Sophie; BILLIEUX, Joel; BRIKEN, Peer; BURKAUSKAS, Julius; CARDENAS-LOPEZ, Georgina; CARVALHO, Joana; CASTRO-CALVO, Jesus; CHEN, Lijun; CIOCCA, Giacomo; CORAZZA, Ornella; CSAKO, Rita; FERNANDEZ, David P.; FUJIWARA, Hironobu; FERNANDEZ, Elaine F.; FUSS, Johannes; GABRHELIK, Roman; GEWIRTZ-MEYDAN, Ateret; GJONESKA, Biljana; GOLA, Mateusz; GRUBBS, Joshua B.; HASHIM, Hashim T.; ISLAM, Md. Saiful; ISMAIL, Mustafa; JIMENEZ-MARTINEZ, C. Martha; JURIN, Tanja; KALINA, Ondrej; KLEIN, Verena; KOLTO, Andras; LEE, Sang-Kyu; LEWCZUK, Karol; LIN, Chung-Ying; LOCHNER, Christine; LOPEZ-ALVARADO, Silvia; LUKAVSKA, Katerina; MAYTA-TRISTAN, Percy; MILLER, Dan J.; OROSOVA, Olga; OROSZ, Gabor; TEAM, Mami Sungkyunkwan Univ res; PONCE, Fernando P.; QUINTANA, Gonzalo R.; GARZOLA, Gabriel C. Quintero; RAMOS-DIAZ, Jano; RIGAUD, Kevin; ROUSSEAU, Ann; SCANAVINO, Marco De Tubino; SCHULMEYER, Marion K.; SHARAN, Pratap; SHIBATA, Mami; SHOIB, Sheikh; SIGRE-LEIROS, Vera; SNIEWSKI, Luke; SPASOVSKI, Ognen; STEIBLIENE, Vesta; STEIN, Dan J.; STRIZEK, Julian; TSAI, Meng-Che; UNSAL, Berk C.; VAILLANCOURT-MOREL, Marie-Pier; HOUT, Marie Claire Van; BOTHEJ, Beata
    Introduction: Despite being a widely used screening questionnaire, there is no consensus on the most appropriate measurement model for the Alcohol Use Disorders Identification Test (AUDIT). Furthermore, there have been limited studies on its measurement invariance across cross-cultural subgroups, genders, and sexual orientations. Aims: The present study aimed to examine the fit of different measurement models for the AUDIT and its measurement invariance across a wide range of subgroups by country, language, gender, and sexual orientation. Methods: Responses concerning past-year alcohol use from the participants of the cross-sectional International Sex Survey were considered (N = 62,943; Mage: 32.73; SD = 12.59). Confirmatory factor analysis, as well as measurement invariance tests were performed for 21 countries, 14 languages, three genders, and four sexual orientation subgroups that met the minimum sample size requirement for inclusion in these analyses. Results: A two-factor model with factors describing 'alcohol use' (items 1-3) and 'alcohol problems' (items 4-10) showed the best model fit across countries, languages, genders, and sexual orientations. For the former two, scalar and latent mean levels of invariance were reached considering different criteria. For gender and sexual orientation, a latent mean level of invariance was reached. Conclusions: In line with the two-factor model, the calculation of separate alcohol-use and alcohol-problem scores is recommended when using the AUDIT. The high levels of measurement invariance achieved for the AUDIT support its use in cross-cultural research, capable also of meaningful comparisons among genders and sexual orientations.
  • article 0 Citação(ões) na Scopus
    Excessive Sexual Drive after Mercury Poisoning: A Case Report
    (2022) ASCIUTTI, Antonio P. R.; MESSINA, Bruna; TAVARES, Hermano; SCANAVINO, Marco D. T.
    Mercury poisoning induces neuropsychiatric symptoms. This study reports a clinical case of Excessive Sexual Drive (ESD) after mercury poisoning and its treatment. A 50-year-old man was referred to treatment because of persistent sexual urge after mercury poisoning. He took paroxetine under medical follow-up and received orientations addressing ESD. His mental status was accessed with neuropsychological test and using psychiatric scales. Sexual urge, impulsivity, and behavior became milder. Scores on neuropsychological test and on scales showed a decrease on anxiety, depression, and impulsivity. ESD can possibly occur after mercury poisoning. Paroxetine showed itself useful to control the sexual urge.