MARCO DE TUBINO SCANAVINO
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
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- Sexual Dysfunctions Among People Living With HIV With Long- Term Treatment With Antiretroviral Therapy(2022) SCANAVINO, Marco De Tubino; MORI, Emi; NISIDA, Vera Vichr; AVELINO-SILVA, Vivian I.; AMARAL, Maria Luiza Sant'ana do; MESSINA, Bruna; SEGURADO, Aluisio CotrimIntroduction: Sexuality plays an essential role in the psychosocial well-being of people living with HIV (PLHIV) but it is still less assessed by healthcare professionals during treatment. Aim: To investigate the frequency of those screening positive for sexual dysfunction (SD) and associated factors according to gender/sexual orientation in PLHIV under long-term treatment with antiretroviral therapy (ART). Methods: Between September 2013 and October 2016, 234 PLHIV adults in treatment in Sao Paulo were included. Participants were sexually active, did not present sexual orientation disorder or body dysmorphicdisor-der, and did not use sexual hormones. We performed clinical interviews and measured levels of depression, anxiety, and levels of sexual hormones. SD was assessed using a self-report questionnaire. Main Outcome Measures: Proportion of participants screening positive for SD in the International Index of Erectile Function, the Index of Premature Ejaculation, and the Female Sexual Function Index. In the regression analyses, the outcome SD considered any SD presented with disregard to gender. Results: 70% of participants reported consistent adherence to ART and 96% had an undetectable viral load. The median (Md) duration of ART was 198 months (inter quartil range, IQR 111.6-230.4) and the median CD4 was 655 cells/mm(3) (IQR 443-871). Screening positive for erectile dysfunction was 49.7%, premature ejaculation 16.9%, female sexual dysfunction 27.4% and hypoactive desire 45.1%. Lower testosterone and prolactin levels were associated with erectile dysfunction in heterosexual men (n = 58); lower levels of oestradiol and higher levels of follicle stimulating hormone were associated with female sexual dysfunction and hypoactive desire in female participants (n = 63). The multivariable model used included comorbidities and hormonal abnormality and found that age (odds ratio, OR = 1.04, 95% confidence interval, 95%CI 1.00-1.08, P = .026) and the presence of depression/anxiety (OR = 2.96; 95%CI 1.52-5.77; P = .001) were associated with SD. Also, men reporting engaging in sex with other men were associated with screening positive for SD (OR 2.66; 95%CI 1.52-5.77, P = .013). During treatment of PLHIV, it is important to evaluate sexual health and symptoms of depression and anxiety specifically. The strength of this study consists in evaluating PLHIV who have been in long-term treatment with ART and analyzing those screening positive for SD and associated factors for each group (heterosexual men, men reporting engaging in sex with other men, and women). Limitation includes the difficulty to generalize the findings of the study, and not exploring women's sexual orientation. Conclusion: PLHIV in long-term treatment with ART presented alarming rates of depression/anxiety which in turn is correlated with sexual and physical health problems.
- Sexual Compulsivity Scale, Compulsive Sexual Behavior Inventory, and Hypersexual Disorder Screening Inventory: Translation, Adaptation, and Validation for Use in Brazil(2016) SCANAVINO, Marco de T.; VENTUNEAC, Ana; RENDINA, H. Jonathon; ABDO, Carmita H. N.; TAVARES, Hermano; AMARAL, Maria L. S. do; MESSINA, Bruna; REIS, Sirlene C. dos; MARTINS, Joao P. L. B.; GORDON, Marina C.; VIEIRA, Julie C.; PARSONS, Jeffrey T.Epidemiological, behavioral, and clinical data on sexual compulsivity in Brazil are very limited. This study sought to adapt and validate the Sexual Compulsivity Scale (SCS), the 22-item version of the Compulsive Sexual Behavior Inventory (CSBI-22), and the Hypersexual Disorder Screening Inventory (HDSI) for use in Brazil. A total of 153 participants underwent psychiatric assessment and completed self-reported measures. The adaptation process of the instruments from English to Portuguese followed the guidelines of the International Society for Pharmacoeconomics and Outcomes Research. The reliability and validity of the HDSI criteria were evaluated and the construct validity of all measures was examined. For the SCS and HDSI, factor analysis revealed one factor for each measure. For the CSBI-22, four factors were retained although we only calculated the scores of two factors (control and violence). All scores had good internal consistency (alpha >.75), presented high temporal stability (>.76), discriminated between patients and controls, and presented strong (rho > .81) correlations with the Sexual Addiction Screening Test (except for the violence domain = .40) and moderate correlations with the Impulsive Sensation Seeking domain of the Zuckerman Kuhlman Personality Questionnaire (rho between .43 and .55). The sensitivity of the HDSI was 71.93 % and the specificity was 100 %. All measures showed very good psychometric properties. The SCS, the HDSI, and the control domain of the CSBI-22 seemed to measure theoretically similar constructs, as they were highly correlated (rho > .85). The findings support the conceptualization of hypersexuality as a cluster of problematic symptoms that are highly consistent across a variety of measures.
- Psychometric properties of the Alcohol Use Disorders Identification Test (AUDIT) across cross-cultural subgroups, genders, and sexual orientations: Findings from the International Sex Survey (ISS)(2023) HORVATH, Zsolt; NAGY, Lena; KOOS, Monika; KRAUS, Shane W.; DEMETROVICS, Zsolt; POTENZA, Marc N.; BALLESTER-ARNAL, Rafael; BATTHYANY, Dominik; BERGERON, Sophie; BILLIEUX, Joel; BRIKEN, Peer; BURKAUSKAS, Julius; CARDENAS-LOPEZ, Georgina; CARVALHO, Joana; CASTRO-CALVO, Jesus; CHEN, Lijun; CIOCCA, Giacomo; CORAZZA, Ornella; CSAKO, Rita; FERNANDEZ, David P.; FUJIWARA, Hironobu; FERNANDEZ, Elaine F.; FUSS, Johannes; GABRHELIK, Roman; GEWIRTZ-MEYDAN, Ateret; GJONESKA, Biljana; GOLA, Mateusz; GRUBBS, Joshua B.; HASHIM, Hashim T.; ISLAM, Md. Saiful; ISMAIL, Mustafa; JIMENEZ-MARTINEZ, C. Martha; JURIN, Tanja; KALINA, Ondrej; KLEIN, Verena; KOLTO, Andras; LEE, Sang-Kyu; LEWCZUK, Karol; LIN, Chung-Ying; LOCHNER, Christine; LOPEZ-ALVARADO, Silvia; LUKAVSKA, Katerina; MAYTA-TRISTAN, Percy; MILLER, Dan J.; OROSOVA, Olga; OROSZ, Gabor; TEAM, Mami Sungkyunkwan Univ res; PONCE, Fernando P.; QUINTANA, Gonzalo R.; GARZOLA, Gabriel C. Quintero; RAMOS-DIAZ, Jano; RIGAUD, Kevin; ROUSSEAU, Ann; SCANAVINO, Marco De Tubino; SCHULMEYER, Marion K.; SHARAN, Pratap; SHIBATA, Mami; SHOIB, Sheikh; SIGRE-LEIROS, Vera; SNIEWSKI, Luke; SPASOVSKI, Ognen; STEIBLIENE, Vesta; STEIN, Dan J.; STRIZEK, Julian; TSAI, Meng-Che; UNSAL, Berk C.; VAILLANCOURT-MOREL, Marie-Pier; HOUT, Marie Claire Van; BOTHEJ, BeataIntroduction: Despite being a widely used screening questionnaire, there is no consensus on the most appropriate measurement model for the Alcohol Use Disorders Identification Test (AUDIT). Furthermore, there have been limited studies on its measurement invariance across cross-cultural subgroups, genders, and sexual orientations. Aims: The present study aimed to examine the fit of different measurement models for the AUDIT and its measurement invariance across a wide range of subgroups by country, language, gender, and sexual orientation. Methods: Responses concerning past-year alcohol use from the participants of the cross-sectional International Sex Survey were considered (N = 62,943; Mage: 32.73; SD = 12.59). Confirmatory factor analysis, as well as measurement invariance tests were performed for 21 countries, 14 languages, three genders, and four sexual orientation subgroups that met the minimum sample size requirement for inclusion in these analyses. Results: A two-factor model with factors describing 'alcohol use' (items 1-3) and 'alcohol problems' (items 4-10) showed the best model fit across countries, languages, genders, and sexual orientations. For the former two, scalar and latent mean levels of invariance were reached considering different criteria. For gender and sexual orientation, a latent mean level of invariance was reached. Conclusions: In line with the two-factor model, the calculation of separate alcohol-use and alcohol-problem scores is recommended when using the AUDIT. The high levels of measurement invariance achieved for the AUDIT support its use in cross-cultural research, capable also of meaningful comparisons among genders and sexual orientations.
- Co-Occurring Obsessive-Compulsive Disorder and Compulsive Sexual Behavior: Clinical Features and Psychiatric Comorbidities(2022) SNAYCHUK, Lindsey A.; FERRAO, Ygor A.; FONTENELLE, Leonardo F.; MIGUEL, Euripedes C.; MATHIS, Maria A. de; SCANAVINO, Marco D. T.; KIM, Hyoun S.Obsessive-compulsive disorder (OCD) commonly co-occurs with other psychiatric conditions. Though research is limited, there is preliminary evidence that OCD also co-occurs with compulsive sexual behavior (CSB). Yet, few studies have investigated the demographic, clinical, and psychiatric comorbidities associated with co-occurring OCD and CSB. To address this gap, the current study aimed to evaluate rates of co-occurring OCD and CSB, identify demographic and clinical factors associated with comorbid OCD and CSB, and assess associated psychiatric comorbidity. Participants (N = 950) were patients of a large multisite treatment for OCD. Standardized self-report measures were used to assess demographic and clinical characteristics such as anxiety, depression, and severity and dimensions of OCD. Semi-structured interviews including the SCID were used to assess psychiatric comorbidities. A total of 36 (3.8%) of participants met the criteria for CSB. Binary logistic regression analysis revealed that males were significantly more likely to present with CSB than females and CSB was associated with greater psychiatric comorbidity, particularly impulse control disorders. These findings suggest that individuals with co-occurring OCD and CSB may have more complex treatment needs, and more tailored interventions may be necessary.
- Female Sexual Function and Gestational Diabetes(2012) RIBEIRO, Meireluci Costa; NAKAMURA, Mary Uchiyama; SCANAVINO, Marco de Tubino; TORLONI, Maria Regina; MATTAR, RosianeIntroduction. The number of women with gestational diabetes mellitus (GDM) is growing worldwide in parallel with the obesity epidemic. The diagnosis of GDM leads to substantial modifications in the daily routine of these women, and these adjustments could potentially affect their sexual function. There are no previous studies on the sexual function of patients with GDM. Aim. The aim of this study was to investigate the sexual function of patients with GDM in comparison with healthy pregnant women at the same gestational age. Methods. Brazilian women in the third trimester of pregnancy with and without GDM were invited to participate in this cross-sectional study while waiting for their antenatal care visits at a single public tertiary teaching institution between March and December 2010. The Brazilian version of the Female Sexual Function Index (FSFI) questionnaire was used to assess sexual function. Main Outcome Measures. Desire, arousal, lubrication, orgasm, sexual satisfaction, and pain during and after coitus in the last 4 weeks, measured according to a standardized and validated questionnaire. Results. A total of 87 participants were enrolled (43 healthy women and 44 with GDM). There were no significant differences in the sociodemographic characteristics of both groups. The total FSFI scores of GDM patients was 21.0 +/- 9.59 compared with 22.3 +/- 9.17 for healthy women (P = 0.523). Difficulty in desire was the most common sexual dysfunction symptom in both groups, being reported by 42% and 50% of GDM and healthy women, respectively (P = 0.585). Conclusion. The sexual function of Brazilian patients with GDM does not differ significantly from that of healthy pregnant women at the same gestational age. Ribeiro MC, Nakamura MU, Scanavino Mde T, Torloni MR, and Mattar R. Female sexual function and gestational diabetes. J Sex Med 2012; 9: 786-792.