EBERVAL GADELHA FIGUEIREDO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Neurologia, Faculdade de Medicina - Docente
LIM/62 - Laboratório de Fisiopatologia Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/62 - Laboratório de Fisiopatologia Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
9 resultados
Resultados de Busca
Agora exibindo 1 - 9 de 9
- The Puzzling Olfactory Groove Schwannoma: A Systematic Review(2011) FIGUEIREDO, Eberval Gadelha; SOGA, Yougi; AMORIM, Robson Luis Oliveira; OLIVEIRA, Arthur Maynart Pereira; TEIXEIRA, Manoel JacobsenWe systematically reviewed the literature concerning the anterior cranial fossa schwannomas to understand their pathogenesis, determine their origin, and standardize the terminology. We performed a MEDLINE, EMBASE, and Science Citation Index Expanded search of the literature; age, gender, clinical presentation, presence or absence of hyposmia, radiological features, and apparent origin were analyzed and tabulated. Cases in a context of neurofibromatosis and nasal schwannomas with intracranial extension were not included. Age varied between 14 and 63 years (mean = 30.9). There were 22 male and 11 female patients. The clinical presentation included seizures (n = 15), headache (n = 16), visual deficits (n = 7), cognitive disturbances (n = 3), and rhinorrhea (n = 1). Hyposmia was present in 14 cases, absent in 13 cases (39.3%), and unreported in five. Homogeneous and heterogeneous contrast enhancement was observed in 14 and 15 cases, respectively. The region of the olfactory groove was the probable site in 96.5%. Olfactory tract could be identified in 39.3%. The most probable origin is the meningeal branches of trigeminal nerve or anterior ethmoidal nerves. Thus, olfactory groove schwannoma would better describe its origin and pathogenesis and should be the term preferentially used to name it.
article 16 Citação(ões) na Scopus Outcomes from intracerebral hemorrhage among patients pre-treated with statins(2011) ROMERO, Flavio Ramalho; BERTOLINI, Eduardo de Freitas; VELOSO, Vanessa Nogueira; VENTUNNI, Leandro; FIGUEIREDO, Eberval G.Objective: 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, have been associated with improved clinical outcomes after ischemic stroke and subarachnoid hemorrhage, but with an increased risk of incidental spontaneous intracerebral hemorrhage (ICH). We investigated whether the statin use before ICH, was associated with functional independence, 90 days after treatment. Method: We analyzed 124 consecutive ICH patients with 90-day outcome data who were enrolled in a prospective cohort study between 2006 and 2009. Eighty-three patients were included in this study. Among ICH survivors, univariate Cox regression models and Kaplan-Meier plots were used to determine subject characteristics that were associated with an increased risk of recurrence. Statin usage was determined through interviewing the patient at the time of ICH and confirmed by reviewing their medical records. Independent status was defined as Glasgow Outcome Scale grades 4 or 5. Results: Statins were used by 20 out of 83 patients (24%) before ICH onset. There was no effect from pre-ICH statin use on functional independence rates (28% versus 29%, P=0.84) or mortality (46% versus 45%, P=0.93). Conclusion: Pre-ICH statin use is not associated with changes to ICH functional outcome or mortality.article 3 Citação(ões) na Scopus Intramedullary granuloma suggestive of tuberculoma(2011) GUIRADO, Vinicius M.; WELLING, Leonardo C.; MELUZZI, Alexandre; SANTOS, Marcelo E. Sette dos; FIGUEIREDO, Eberval Gadelha; TARICCO, Mario Augusto; TEIXEIRA, Manoel Jacobsen- Serum sodium disorders in patients with traumatic brain injury(2011) PAIVA, Wellingson Silva; BEZERRA, Douglas Alexandre Franca; AMORIM, Robson Luis Oliveira; FIGUEIREDO, Eberval Gadelha; TAVARES, Wagner Malago; ANDRADE, Almir Ferreira De; TEIXEIRA, Manoel JacobsenSodium disorders are the most common and most poorly understood electrolyte disorders in neurological patients. The aim of this study was to determine the incidence of sodium disorders and its association with different traumatic brain injuries. This prospective study was conducted in 80 patients diagnosed with moderate and severe traumatic brain injuries. All patients underwent cerebral computed tomography. Incidence of sodium disorders, presence of injuries in the first computed tomography after traumatic brain injury, and level of consciousness were analyzed. Patients that presented other potential causes of sodium disorders and systemic trauma were excluded from the study. The incidence of sodium disturbances was 45%: 20 patients presented hypernatremia and 16 hyponatremia. Refers to all patients with sodium disturbances 53% were detected in the first sample. We recorded at least one measurement <125 mEq/L in 50% of the patients with hyponatremia. A greater incidence of sodium disorders was found in patients with subdural, intracerebral hematoma and with diffuse axonal injury. The incidence of sodium disorders among the patients with diffuse lesions was greater than in the group of patients with brain contusion (P = 0.022). The incidence of sodium disorders is higher in patients with diffuse traumatic brain injuries. No association was found between focal lesions and proportion of sodium disorders. Keywords: brain trauma, hypernatremia, hyponatremia
- Is It Solely Aquaporins? The Mechanisms of Brain Edema ...(2011) WELLING, Leonardo C.; FIGUEIREDO, Eberval G.
article 19 Citação(ões) na Scopus Continuous ventricular cerebrospinal fluid drainage with intracranial pressure monitoring for management of posttraumatic diffuse brain swelling(2011) ANDRADE, Almir Ferreira de; PAIVA, Wellingson Silva; AMORIM, Robson Luis Oliveira de; FIGUEIREDO, Eberval Gadelha; ALMEIDA, Antonio Nogueira de; BROCK, Roger Schmidt; BOR-SENG-SHU, Edson; TEIXEIRA, Manoel JacobsenBackground: Ventricular drainage has played an important role in the management of traumatic brain-injured patients. The aim of the present study was describe outcomes in a series of 57 patients with diffuse brain swelling underwent to intracranial pressure (ICP) monitoring. Method: Fifty-eight patients with diffuse posttraumatic brain swelling, were evaluated prospectively. The Glasgow Coma Scale (GCS) scores of patients varied from 4 to 12. Patients groups divided according to GCS and age. Patient neurological assessment was classified as favorable, unfavorable, and death. Results: Mechanisms of injury were vehicle accidents in 72.4% and falls in 15.6%. 54% of patients had GCS scores between 6 and 8. There were no statistical differences, regarding outcome, between groups separated by age. In the adults group (n=47), 44.7% evolved favorably. Conclusion: Our results indicate a poor prognosis in patients with brain swelling. We believe that continuous ventricular CSF drainage with ICP monitoring is a simple method as an adjunct in the management of these patients.article 8 Citação(ões) na Scopus Fisher revised scale for assessment of prognosis in patients with subarachnoid hemorrhage(2011) OLIVEIRA, Arthur Maynart Pereira; PAIVA, Wellingson Silva; FIGUEIREDO, Eberval Gadelha de; OLIVEIRA, Hello Araujo; TEIXEIRA, Manoel JacobsenThe Fisher revised scale (FRS) presents an alternative for evaluating patients with subarachnoid hemorrhage (SAH). In this study, we compared the prognosis of patients with SAH and vasospasms (VSP). Method: This was a prospective study on patients with a diagnosis of aneurysmal SAH, 72 hours after the initial event. Sequential neurological examinations and Hunt and Hess (HaH) score were performed on the 1(st), 7(th) and 14(th) days. Transcranial Doppler was used to assess vasospasms. Results: Out of the 24 patients studied, ten (41.66%) presented a delayed neurological deficit, such as diminished consciousness, decreased HaH score or death. The single patient classified as FS-1 did not have any delayed neurological deficit, while such deficits evolved in one patient out of five with FS-2 (20%); two out of seven with FS-3 (28.57%) and seven out of 11 with FS-4 (63.63%). Conclusion: Level three of the FS and FRS seemed to be compatible with regard to predicting the likelihood of progression to severe VSP.- Multiple epidural haematomas after meningioma surgery(2011) WELLING, Leonardo C.; GUIRADO, Vinicius; SANTOS, Marcelo E. Sette Dos; AGUIAR, Guilherme Brasileiro De; FIGUEIREDO, Eberval G.Intracranial meningioma removal carries a higher risk of post-operative haemorrhage compared with other intracranial neoplasm surgeries. We report a patient who developed three intracranial haematomas following a frontal meningioma removal.
article Minimally Invasive Transpalpebral ""Eyelid"" Approach to the Anterior Cranial Base COMMENTS(2011) MANDEL, Mauricio; FIGUEIREDO, Eberval G.; OLIVERA, Raul; LOVEREN, Harry van; REISCH, Robert; MITCHELL, Patrick