HAMILTON AUGUSTO ROSCHEL DA SILVA

(Fonte: Lattes)
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EFE, EEFE - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina

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Assunto: Sport Sciences ×

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Agora exibindo 1 - 10 de 24
  • conferenceObject
    Does Exclusive Consumption of Plant-based Dietary Protein Impair Resistance Training-induced Muscle Adaptations?
    (2019) HEVIA-LARRAIN, Victoria; LONGOBARDI, Igor; LINS, Alan F.; PEREIRA, Rosa M.; ARTIOLI, Guilherme; PHILLIPS, Stuart M.; GUALANO, Bruno; ROSCHEL, Hamilton
  • conferenceObject
    Effects Of Exercise Training On Strength And Functionality In Obese Subjects Undergoing Bariatric Surgery: Preliminary Findings
    (2018) ROSCHEL, Hamilton; GIL, Saulo; DANTAS, Wagner S.; MURAI, Igor H.; MEREGE FILHO, Carlos; SANTO, Marco A.; CLEVA, Roberto; GUALANO, Bruno
  • article 141 Citação(ões) na Scopus
    Placebo in sports nutrition: a proof-of-principle study involving caffeine supplementation
    (2017) SAUNDERS, B.; OLIVEIRA, L. F. de; SILVA, R. P. da; PAINELLI, V. de Salles; GONCALVES, L. S.; YAMAGUCHI, G.; MUTTI, T.; MACIEL, E.; ROSCHEL, H.; ARTIOLI, G. G.; GUALANO, B.
    We investigated the effects of supplement identification on exercise performance with caffeine supplementation. Forty-two trained cyclists (age 37 +/- 8years, body mass [BM] 74.3 +/- 8.4kg, height 1.76 +/- 0.06m, maximum oxygen uptake 50.0 +/- 6.8mL/kg/min) performed a similar to 30min cycling time-trial 1h following either 6mg/kgBM caffeine (CAF) or placebo (PLA) supplementation and one control (CON) session without supplementation. Participants identified which supplement they believed they had ingested (caffeine, placebo, don't know) pre- and post-exercise. Subsequently, participants were allocated to subgroups for analysis according to their identifications. Overall and subgroup analyses were performed using mixed-model and magnitude-based inference analyses. Caffeine improved performance vs PLA and CON (P0.001). Correct pre- and post-exercise identification of caffeine in CAF improved exercise performance (+4.8 and +6.5%) vs CON, with slightly greater relative increases than the overall effect of caffeine (+4.1%). Performance was not different between PLA and CON within subgroups (all P>0.05), although there was a tendency toward improved performance when participants believed they had ingested caffeine post-exercise (P=0.06; 87% likely beneficial). Participants who correctly identified placebo in PLA showed possible harmful effects on performance compared to CON. Supplement identification appeared to influence exercise outcome and may be a source of bias in sports nutrition.
  • conferenceObject
    Optimising Sodium Bicarbonate Supplementation: Are Gastro-resistant Capsules The Answer?
    (2018) OLIVEIRA, Luana F.; SAUNDERS, Bryan; YAMAGUCHI, Guilherme; GUALANO, Bruno; ROSCHEL, Hamilton; ARTIOLI, Guilherme G.
  • conferenceObject
    Chronic (24 weeks) Beta-alanine Supplementation Does Not Affect Muscle Taurine Or Blood Clinical Chemistry
    (2018) SAUNDERS, Bryan; FRANCHI, Mariana; OLIVEIRA, Luana F.; PAINELLI, Vitor S.; SILVA, Vinicius E.; SILVA, Rafael P.; COSTA, Luiz A. R.; SALE, Craig; HARRIS, Roger C.; ROSCHEL, Hamilton; ARTIOLI, Guilherme G.; GUALANO, Bruno
  • conferenceObject
    Exercise Mitigates The Loss In Muscle Mass And Functionality In Obese Women Undergoing Bariatric Surgery
    (2019) GIL, Saulo; DANTAS, Wagner Silva; MURAI, Igor Hisashi; MEREGE FILHO, Carlos; SANTO, Marco Aurelio; CLEVA, Roberto de; PEREIRA, Rosa Maria Rodrigues; SHINJO, Samuel Katsuyuki; KIRWAN, John P.; GUALANO, Bruno; ROSCHEL, Hamilton
  • article 4 Citação(ões) na Scopus
    Creatine O'Clock: Does Timing of Ingestion Really Influence Muscle Mass and Performance?
    (2022) CANDOW, Darren G.; FORBES, Scott C.; ROBERTS, Michael D.; ROY, Brian D.; ANTONIO, Jose; SMITH-RYAN, Abbie E.; RAWSON, Eric S.; GUALANO, Bruno; ROSCHEL, Hamilton
    It is well-established that creatine supplementation augments the gains in muscle mass and performance during periods of resistance training. However, whether the timing of creatine ingestion influences these physical and physiological adaptations is unclear. Muscle contractions increase blood flow and possibly creatine transport kinetics which has led some to speculate that creatine in close proximity to resistance training sessions may lead to superior improvements in muscle mass and performance. Furthermore, creatine co-ingested with carbohydrates or a mixture of carbohydrates and protein that alter insulin enhance creatine uptake. The purpose of this narrative review is to (i) discuss the purported mechanisms and variables that possibly justify creatine timing strategies, (ii) to critically evaluate research examining the strategic ingestion of creatine during a resistance training program, and (iii) provide future research directions pertaining to creatine timing.
  • article 14 Citação(ões) na Scopus
    Effects of acute aerobic exercise on leukocyte inflammatory gene expression in systemic lupus erythematosus
    (2016) PERANDINI, L. A.; SALES-DE-OLIVEIRA, D.; ALMEIDA, D. C.; AZEVEDO, H.; MOREIRA-FILHO, C. A.; CENEDEZE, M. A.; BENATTI, F. B.; LIMA, F. R.; BORBA, E.; BONFA, E.; SA-PINTO, A. L.; ROSCHEL, H.; CAMARA, N. O.; GUALANO, B.
    Systemic lupus erythematosus (SLE) is an autoimmune disease with a persistent systemic inflammation. Exercise-induced inflammatory response in SLE remains to be fully elucidated. The aim of this study was to assess the effects of acute exercise on leukocyte gene expression in active (SLEACTIVE) and inactive SLE (SLEINACTIVE) patients and healthy controls (HC). Methods: All subjects (n = 4 per group) performed a 30-min single bout of acute aerobic exercise (similar to 70% of VO2 peak) on a treadmill, and blood samples were collected for RNA extraction from circulating leukocyte at baseline, at the end of exercise, and after three hours of recovery. The expression of a panel of immune-related genes was evaluated by a quantitative PCR array assay. Moreover, network-based analyses were performed to interpret transcriptional changes occurring after the exercise challenge. Results: In all groups, a single bout of acute exercise led to the down-regulation of the gene expression of innate and adaptive immunity at the end of exercise (e.g., TLR3, IFNG, GATA3, FOXP3, STAT4) with a subsequent up-regulation occurring upon recovery. Exercise regulated the expression of inflammatory genes in the blood leukocytes of the SLE patients and HC, although the SLE groups exhibited fewer modulated genes and less densely connected networks (number of nodes: 29, 40 and 58; number of edges: 29, 60 and 195; network density: 0.07, 0.08 and 0.12, for SLEACTIVE, SLEINACTIVE and HC, respectively). Conclusion: The leukocytes from the SLE patients, irrespective of disease activity, showed a down-regulated inflammatory gene expression immediately after acute aerobic exercise, followed by an up-regulation at recovery. Furthermore, less organized gene networks were observed in the SLE patients, suggesting that they may be deficient in triggering a normal exercise-induced immune transcriptional response.
  • article 5 Citação(ões) na Scopus
    Effects of a 16-week home-based exercise training programme on health-related quality of life, functional capacity, and persistent symptoms in survivors of severe/critical COVID-19: a randomised controlled trial
    (2023) LONGOBARDI, Igor; GOESSLER, Karla; JR, Gersiel Nascimento de Oliveira; PRADO, Danilo Marcelo Leite do; SANTOS, Jhonnatan Vasconcelos Pereira; MELETTI, Matheus Molina; ANDRADE, Danieli Castro Oliveira de; GIL, Saulo; BOZA, Joao Antonio Spott de Oliveira; LIMA, Fernanda Rodrigues; GUALANO, Bruno; ROSCHEL, Hamilton
    Background Long-lasting effects of COVID-19 may include cardiovascular, respiratory, skeletal muscle, metabolic, psychological disorders and persistent symptoms that can impair health-related quality of life (HRQoL). We investigated the effects of a home-based exercise training (HBET) programme on HRQoL and health-related outcomes in survivors of severe/critical COVID-19. Methods This was a single-centre, single-blinded, parallel-group, randomised controlled trial. Fifty survivors of severe/ critical COVID-19 (5 +/- 1 months after intensive care unit discharge) were randomly allocated (1:1) to either a 3 times a week (similar to 60-80min/session), semi-supervised, individualised, HBET programme or standard of care (CONTROL). Changes in HRQoL were evaluated through the 36-Item Short-Form Health Survey, and physical component summary was predetermined as the primary outcome. Secondary outcomes included cardiorespiratory fitness, pulmonary function, functional capacity, body composition and persistent symptoms. Assessments were performed at baseline and after 16 weeks of intervention. Statistical analysis followed intention-to-treat principles. Results After the intervention, HBET showed greater HRQoL score than CONTROL in the physical component summary (estimated mean difference, EMD: 16.8 points; 95% CI 5.8 to 27.9; effect size, ES: 0.74), physical functioning (EMD: 22.5 points, 95% CI 6.1 to 42.9, ES: 0.83), general health (EMD: 17.4 points, 95%CI 1.8 to 33.1, ES: 0.73) and vitality (EMD: 15.1 points, 95%CI 0.2 to 30.1, ES: 0.49) domains. 30-second sit-to-stand (EMD: 2.38 reps, 95%CI 0.01 to 4.76, ES: 0.86), and muscle weakness and myalgia were also improved in HBET compared with CONTROL (p<0.05). No significant differences were seen in the remaining variables. There were no adverse events. Conclusion HBET is an effective and safe intervention to improve physical domains of HRQoL, functional capacity and persistent symptoms in survivors of severe/critical COVID-19. Trial registration number NCT04615052.
  • article 6 Citação(ões) na Scopus
    Benefits of Home-Based Exercise Training Following Critical SARS-CoV-2 Infection: A Case Report
    (2022) LONGOBARDI, Igor; PRADO, Danilo Marcelo Leite do; GOESSLER, Karla Fabiana; OLIVEIRA JUNIOR, Gersiel Nascimento de; ANDRADE, Danieli Castro Oliveira de; GUALANO, Bruno; ROSCHEL, Hamilton
    In the current scenario, in which an elevated number of COVID-19 survivors present with severe physical deconditioning, exercise intolerance, persistent symptoms, and other post-acute consequences, effective rehabilitation strategies are of utmost relevance. In this study, we report for the first time the effect of home-based exercise training (HBET) in a survivor patient from critical COVID-19 illness. A 67-year-old woman who had critical COVID-19 disease [71 days of hospitalization, of which 49 days were in the intensive care unit (ICU) with invasive mechanical ventilation due to respiratory failure] underwent a 10-week HBET aiming to recovering overall physical condition. Before and after the intervention, we assessed cardiopulmonary parameters, skeletal muscle strength and functionality, fatigue severity, and self-reported persistent symptoms. At baseline (3 months after discharge), she presented with severe impairment in cardiorespiratory functional capacity (<50% age predicted VO2peak). After the intervention, remarkable improvements in VO2peak (from 10.61 to 15.48 mL center dot kg(-1)center dot min(-1), Delta: 45.9%), oxygen uptake efficiency slope (OUES; from 1.0 to 1.3 L center dot min(-1), Delta: 30.1%), HR/VO2 slope (from 92 to 52 bpm center dot L-1, Delta: -43.5%), the lowest VE/VCO2 ratio (from 35.4 to 32.9 L center dot min(-1), Delta: -7.1%), and exertional dyspnea were observed. In addition, handgrip strength (from 22 to 27 kg, Delta: 22.7%), 30-s Sit-to-Stand (30-STS; from 14 to 16 repetitions, Delta:14.3%), Timed-Up-and-Go (TUG; from 8.25 to 7.01 s, Delta: -15%) performance and post-COVID functional status (PCFS) score (from 4 to 2) were also improved from baseline to post-intervention. Self-reported persistent symptoms were also improved, and Fatigue Severity Scale (FSS) score decreased (from 4 to 2.7) from baseline to post-intervention. This is the first evidence that a semi-supervised, HBET program may be safe and potentially effective in improving cardiorespiratory and physical functionality in COVID-19 survivors. Controlled studies are warranted to confirm these findings.