REGINA MARIA DE CARVALHO PINTO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
11 resultados
Resultados de Busca
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conferenceObject Effects of exercise training in a weight loss lifestyle intervention on clinical control, quality of life and psychosocial symptoms in obese asthmatics: A RCT(2014) FREITAS, Patricia D.; FERREIRA, Palmira G.; ANALUCI, S.; STELMACH, Rafael; PINTO, Regina C.; SAGE, Joao M.; MARTINS, Milton A.; MANCINI, Marcio C.; CARVALHO, Celso R. F.conferenceObject Comparison Between Aerobic And Breathing Exercises On Clinical Control And Psychosocial Morbidity In Severe Asthmatics(2014) SACCOMANI, Milene G.; EVARISTO, Karen B.; CUKIER, Alberto; STELMACH, Rafael; CARVALHO-PINTO, Regina; ROJO, Marcos; SANTAELLA, Danilo F.; MARTINS, Milton A.; CARVALHO, Celso R. F.- Comparison against baseline in randomised control trials (again)(2014) DIAS-JUNIOR, Servulo Azevedo; STELMACH, Rafael; CARVALHO-PINTO, Regina Maria de; CUKIER, Alberto
conferenceObject Clinical, functional and microbiological characteristics of an adult br Tian cystic fibrosis population(2014) RACHED, Samia Zahi; ATHANAZIO, Rodrigo; MAIORANO, Maria Cecilia Nieves Teixeira; FERNANDES, Frederico; CARVALHO-PINTO, Regina; CUKIER, Alberto; STELMACH, RafaelconferenceObject Versican, tenascin, periostin and IL-17A+cells in severe asthma(2014) MAUAD, Thais; FERREIRA, Diogenes S.; ANNONI, Raquel; OLIVEIRA, Bianca L.; KATAYAMA, Edgard H.; CARVALHO-PINTO, Regina M.; RABE, Klaus F.; CUKIER, Alberto; STELMACH, Rafael; DOLHNIKOFF, Marisa- Effects of weight loss on asthma control in obese patients with severe asthma(2014) DIAS-JUNIOR, Servulo Azevedo; REIS, Monica; CARVALHO-PINTO, Regina Maria de; STELMACH, Rafael; HALPERN, Alfredo; CUKIER, AlbertoStudies on the effects of weight loss in patients with asthma are scarce. No studies have been performed in patients with severe asthma. Therefore, the aim of the present study was to assess the impact of weight loss in patients with severe asthma associated with obesity. This was an open, prospective, randomised study of two parallel groups, in patients with severe uncontrolled asthma and moderate obesity. The primary outcome was the level of asthma control 6 months after initiation of the weight reduction programme, quantified using the Asthma Control Questionnaire (ACQ). We evaluated clinical parameters, lung function, markers of airway inflammation and circulating cytokines. 22 patients were randomised to undergo treatment for obesity and 11 to the control group. The weight reduction programme was associated with significant improvements in asthma control (mean +/- SE ACQ score 3.02 +/- 0.19 to 2.25 +/- 0.28 in the treatment group versus 2.91 +/- 0.25 to 2.90 +/- 0.16 in the controls, p=0.001). This improvement was not accompanied by changes in markers of airway inflammation or bronchial reactivity, but by an increase in forced vital capacity. Our results suggest that weight reduction in obese patients with severe asthma improves asthma outcomes by mechanisms not related to airway inflammation.
- Barriers associated with reduced physical activity in COPD patients(2014) AMORIM, Priscila Batista; STELMACH, Rafael; CARVALHO, Celso Ricardo Fernandes; FERNANDES, Frederico Leon Arrabal; CARVALHO-PINTO, Regina Maria; CUKIER, AlbertoObjective: To evaluate the ability of COPD patients to perform activities of daily living (ADL); to identify barriers that prevent these individuals from performing ADL; and to correlate those barriers with dyspnea severity, six-minute walk test (6MWT), and an ADL limitation score. Methods: In COPD patients and healthy, age-matched controls, the number of steps, the distance walked, and walking time were recorded with a triaxial accelerometer, for seven consecutive days. A questionnaire regarding perceived barriers and the London Chest Activity of Daily Living (LCADL) scale were used in order to identify the factors that prevent the performance of ADL. The severity of dyspnea was assessed with two scales, whereas submaximal exercise capacity was determined on the basis of the 6MWT. Results: We evaluated 40 COPD patients and 40 controls. In comparison with the control values, the mean walk time was significantly shorter for COPD patients (68.5 +/- 25.8 min/day vs. 105.2 +/- 49.4 min/ day; p < 0.001), as was the distance walked (3.9 +/- 1.9 km/day vs. 6.4 +/- 3.2 km/day; p < 0.001). The COPD patients also walked fewer steps/day. The most common self-reported barriers to performing ADL were lack of infrastructure, social influences, and lack of willpower. The 6MWT distance correlated with the results obtained with the accelerometer but not with the LCADL scale results. Conclusions: Patients with COPD are less active than are healthy adults of a comparable age. Physical inactivity and the barriers to performing ADL have immediate implications for clinical practice, calling for early intervention measures.
conferenceObject Quantitative Airway Wall Thickness In Severe Asthmatic Patients: An Useful Prognostic Tool But Not Predictor To Therapy(2014) ATHANAZIO, R. A.; CARVALHO-PINTO, R.; JASINOWODOLINSKI, D.; RACHED, S. Z.; MAIORANO, M. C.; FERNANDES, F. L. A.; RABE, K.; CUKIER, A.; STELMACH, R.conferenceObject A Case Of Association Of Pulmonary Actinomycosis And Chronic Cavitary Pulmonary Aspergillosis(2014) RACHED, S. Z.; MAIORANO, M. C. N. T.; ALMEIDA, G. Eler De; ATHANAZIO, R.; CARVALHO-PINTO, R.; FERNANDES, F. Leon Arrabal; STELMACH, R.; CUKIER, A.conferenceObject AIRWAY REMODELING DIFFERENTIATES ALLERGIC FROM NONALLERGIC SEVERE ASTHMA(2014) FERREIRA, Diogenes S.; ANNONI, Raquel; CARVALHO-PINTO, Regina M.; KATAYAMA, Edgard H.; FRARI, Heloisa S. Del; OLIVEIRA, Bianca L.; RABE, Klaus F.; CUKIER, Alberto; STELMACH, Rafael; DOLHNIKOFF, Marisa; MAUAD, Thais