NATHALI CORDEIRO PINTO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
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- Post-operative uses of low-level laser therapy(2016) CHAVANTES, M. C.; PINTO, N. C.; HOLANDA, V. M.In our surgical experience, the use of low-level laser therapy (LLLT) can decrease complications in several major surgeries such as neurosurgery, major abdominal surgery (bariatric surgery), breast reconstruction (TRAM flap) surgical procedures, major burn surgery, and thoracic-cardiovascular surgery. LLLT can accelerate tissue repair, facilitating cicatrization and providing an analgesic effect in post-surgical pain. LLLT can also prevent morbidity, avoiding undesirable outcomes that could be evolving to post-operative death [1]. Although no single tool or technique is yet available to address the many complex issues surgeons face in their everyday practice, this remarkable devicemay be highly beneficial for patients by mitigating their suffering and quite rewarding for doctors. © 2017 Pan Stanford Publishing Pte. Ltd.
- The use of a high-power laser on swine mitral valve chordae tendineae(2016) PINTO, Nathali Cordeiro; CHAVANTES, M. Cristina; ZEZELL, Denise; DEANA, Alessandro; BENETTI, Carolina; MARCOS, Rodrigo Labat; LOPES, Luciana Almeida; MARTINS, Rodrigo A. B. Lopes; AIELLO, Vera Demarchi; JATENE, Fabio Biscegli; POMERANTZEFF, Pablo M. A.Worldwide, rheumatic fever remains a significant cause of mitral valve insufficiency. It is responsible for approximately 90 % of early childhood valvular surgeries in Brazil. Elongated or flail chordae are frequently responsible and require surgical correction. The purpose of this study was to analyze and compare the histological tissues of the mitral valve chordae and the mechanical resistance generated by the chordae, both with and without the application of a high-power laser. Twenty normal porcine mitral valve chordae were measured and divided randomly into the following two groups: control group (not subjected to a high-power laser) and laser group (subjected to photonic irradiation). Laser surgery was performed under controlled conditions, using following parameters: lambda = 980-nm wavelength, power = 3 W, and energy = 60 J. A mechanical test machine was used in combination with a subsequent histological study to measure chordae tensile properties. A histological analysis demonstrated a typical collagen bundle arrangement in the control group; however, under a particular reached temperature range (48), the collagen bundles assumed different arrangements in the laser group. Significant reductions in the chordae tendineae lengths and changes in their resistance in the laser group were observed, as these chordae exhibited less rigid fibers. The chordae tendineae of normal porcine valves subjected to a high-power laser exhibited its length reduction and less stiffness compared to the control group. A histological analysis of the laser treatment specimens demonstrated differences in collagen bundle spatial organization, following slight changes into tissue temperature.