MARCOS NAOYUKI SAMANO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cardio-Pneumologia, Faculdade de Medicina - Docente
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
12 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 12
conferenceObject Management of Tuberculosis After Lung Transplantation in na Endemic Region(2017) CAMPOS, S. V.; SAMANO, M. N.; PEGO-FERNANDES, P. M.; TEIXEIRA, R. O.; FERNANDES, L. M.; ABDALLA, L. G.; CARRARO, R. M.; AFONSO-JUNIOR, J. E.; COSTA, A. N.bookPart Cateter venoso central subclávio(2017) SILVA, Guilherme Diogo; NOGUEIRA, Thiago Machado; SAMANO, Marcos Naoyuki; SILVA, Francisco de Salles Collet e; ANDRADE, Mauro Figueiredo Carvalho de; PêGO-FERNANDES, Paulo ManuelbookPart Pericardiocentese de emergência(2017) SILVA, Guilherme Diogo; NOGUEIRA, Thiago Machado; SAMANO, Marcos Naoyuki; SILVA, Francisco de Salles Collet e; ANDRADE, Mauro Figueiredo Carvalho de; PêGO-FERNANDES, Paulo Manuel- Experience of Lung Transplantation in Patients with Lymphangioleiomyomatosis at a Brazilian Reference Centre(2017) BALDI, Bruno Guedes; SAMANO, Marcos Naoyuki; CAMPOS, Silvia Vidal; OLIVEIRA, Martina Rodrigues de; AFONSO JUNIOR, Jose Eduardo; CARRARO, Rafael Medeiros; TEIXEIRA, Ricardo Henrique Oliveira Braga; MINGUINI, Isabela Pasqualini; BURLINA, Roni; PATO, Eduardo Zinoni Silva; CARVALHO, Carlos Roberto Ribeiro; COSTA, Andre NathanLung transplantation (LT) is the standard of care for patients with advanced lung diseases, including lymphangioleiomyomatosis (LAM). LAM accounts for only 1% of all LTs performed in the international registry. As a result, the global experience, including the use of mechanistic target of rapamycin (mTOR) inhibitors before and after LT in LAM, is still limited. We conducted a retrospective review of all LAM patients who underwent LT at our centre between 2003 and 2016. Pre- and post-transplant data were assessed. Eleven women with LAM underwent LT, representing 3.3% of all procedures. Ten (91%) patients underwent double-LT. The mean age at diagnosis was 39 +/- 6 years and the mean FEV1 before LT was 28 +/- 14%. Only one patient underwent pleurodesis for recurrent pneumothorax. Pulmonary hypertension was confirmed in 3 (27%) patients. Four (36%) patients received sirolimus preoperatively; three of them received it until the day of LT, and there was no occurrence of bronchial anastomotic dehiscence after the procedure. Four patients (36%) received mTOR inhibitors post-transplant. The median follow-up from LT was 44 months. There were 3 deaths (27%) during the study and survival probabilities at 1, 3, and 5 years after LT were, 90, 90, and 77%, respectively. This data reinforces the role of LT for LAM patients with end-stage disease. The use of sirolimus seems to be safe before LT and the occurrence of complications after LT, including those LAM-related, should be continuously monitored.
- Abdominal Complications After Lung Transplantation in a Brazilian Single Center(2017) COSTA, H. F.; REIS, F. P. dos; GOMES-JUNIOR, O.; FERNANDES, L. M.; ABDALLA, L. G.; CAMPOS, S. V.; TEIXEIRA, R. H. O. B.; SAMANO, M. N.; PEGO-FERNANDES, P. M.Surgical and nonsurgical abdominal complications have been described after lung transplantation. However, there is limited data on this event in this population. The objective of this study was to analyze the incidence of abdominal complications in patients undergoing lung transplantation at the Heart Institute of the Faculty of Medicine, University of Sao Paulo (InCor-HCFMUSP) between the years 2003 and 2016. The main causes of abdominal complications were inflammatory acute abdomen (7 patients; 14%), obstructive acute abdomen (9 patients; 18%), gastroparesis (4 patients; 8%), distal intestinal obstruction syndrome (4 patients; 8%), perforated acute abdomen (7 patients; 14%), cytomegalovirus (CMV; 6 patients; 12%), and other reasons (12 patients; 26%). Separating these patients according to Clavien-Dindo classification, we had 21 patients (43%) with complications grade II, 4 patients (8%) with complications grade ilia, 7 patients (14%) with grade Illb complications, 7 patients (14%) with grade IV complications, and 10 patients (21%) with grade complications V. In conclusion, abdominal disorders are seriously increased after lung transplantation and correlate with a high mortality. Early abdominal surgical complication has worse prognosis.
- Abdominal Complications After Lung Transplantation in a Brazilian Single Center (vol 49, pg 878, 2017)Y(2017) COSTA, H. F.; REIS, F. P. dos; GOMES-JUNIOR, O.; FERNANDES, L. M.; ABDALLA, L. G.; CAMPOS, S. V.; TEIXEIRA, R. H. O. B.; SAMANO, M. N.; PEGO-FERNANDES, P. M.
conferenceObject Clinical Assessment of Cytomegalovirus Specific Cell Mediated Immunity in a Prospective Cohort of Lung Transplant Recipients(2017) CAMPOS, S. V.; SAMANO, M. N.; PEGO-FERNANDES, P. M.; TEIXEIRA, R. O.; CARRARO, R. M.; AFONSO-JUNIOR, J. E.; COSTA, A. N.; MACHADO, C. M.; SOUZA, A. C.; PEREIRA, B. B.; FERNANDES, L. M.; ABDALLA, L.- Lung transplantation for lymphangioleiomyomatosis: a Brazilian centre experience(2017) OLIVEIRA, Martina; BALDI, Bruno Guedes; SAMANO, Marcos Naoyuki; CAMPOS, Silvia Vidal; TEIXEIRA, Ricardo Henrique Oliveira Braga; MINGUINI, Isabela Pasqualini; BURLINA, Roni; PATO, Eduardo Zinoni Silva; CARVALHO, Carlos Roberto Ribeiro; COSTA, Andre Nathan
- Incidence and Mortality by Cancer in Patients After Lung Transplantation in a Brazilian Institution(2017) SCHETTINI-SOARES, M.; JUNIOR, O. G.; COSTA, H. F.; FERNANDES, L. M.; ABDALLA, L. G.; CAMPOS, S. V.; TEIXEIRA, R. H. O. B.; SAMANO, M. N.; PEGO-FERNANDES, P. M.Background. The first human lung transplantation was performed by James Hardy in 1963 due to lung cancer. Currently, malignancy has its importance in the follow-up of transplanted patients because cancer risk is higher in this population and the main risk factor for this augmentation is immunosuppression. The most common types of cancer are non-melanoma skin cancer and post-transplantation lymphoproliferative diseases. The objective of this study is to measure the cancer incidence and its related mortality in lung-transplanted patients of a Brazilian institution. Methods. Review of the records of the 263 patients who underwent lung transplantation between April 2000 and April 2016 at the Heart Institute (InCor), focusing on the incidence of cancer, most common types of malignancies, and cancer mortality rate. We compared incidence and mortality with the International Society for Heart and Lung Transplantation (ISHLT) database. Results. During the 16-year period, the total incidence of cancer was 10.3% with 27 cases diagnosed in 21 patients. The most common types of cancer were non-melanoma skin cancer, prostate cancer, and post-transplantation lymphoproliferative diseases. Comparing the incidences after 1-year, 5-year, and 10-year follow-up with the ISHLT database, they were similar in the first two periods and higher in the third period. As to cancer mortality rate, it was similar to the ISHLT database in both periods analyzed. Conclusion. The incidence of malignancies was higher in our transplanted patients in comparison with the Brazilian population, and the most frequent types of cancer are in accordance with the literature, except for prostate cancer. Cancer mortality rate was similar to that from the ISHLT database.
bookPart Drenagem de tórax(2017) NOGUEIRA, Thiago Machado; SILVA, Guilherme Diogo; SAMANO, Marcos Naoyuki; SILVA, Francisco de Salles Collet e; ANDRADE, Mauro Figueiredo Carvalho de; PêGO-FERNANDES, Paulo Manuel