RODRIGO CARUSO CHATE
Índice h a partir de 2011
7
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/65, Hospital das Clínicas, Faculdade de Medicina
LIM/65, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject THE IMPACT OF PLEURAL CATHETER POSITION ON THE SUCCESS OF BEDSIDE PLEURODESIS(2014) TERRA, Ricardo Mingarini; ARAUJO, Pedro Henrique Xavier Nabuco de; CHATE, Rodrigo Caruso; PEGO-FERNANDES, Paulo- What happens to the pleural space affected by malignant effusion after bedside pleurodesis?(2018) ARAUJO, Pedro H. X. N. de; TERRA, Ricardo M.; SANTOS, Thiago da Silva; CHATE, Rodrigo C.; PAIVA, Antonio F. L. de; PEGO-FERNANDES, Paulo M.Background and objectivesEvaluate radiological characteristics of postpleurodesis pleural space of patients with recurrent malignant pleural effusion(RMPE). MethodsProspective cohort study including patients with RPME treated with bedside pleurodesis. We used CT scans to calculate pleural cavity volume immediately before pleurodesis(iCT) and 30 days after(CT30). Radiological evolution was calculated by the difference between pleural volumes on CT30 and iCT(volume). We categorized initial pleural volume as small(<500mL) or large space(500mL) and volume as positive(>254.49mL), unchanged(-268.77-254.49mL), or negative(<-268.77mL). Futhermore, we analyzed clinical effectiveness, pleural elastance, and adverse events. ResultsA total of 87 patients were analyzed. Pleural volume varied from 35-2750mL in iCT and from 0-2995mL in CT30(P=0.753). A total of 54 patients had initial small pleural space(62.06%) and 33 large(37.93%). Clinical failure occurred in 7.4% of small space group and in 24.6% of large(P=0.051, OR4.0(CI:1.098-14.570)). In small space group, 27.77% evolved with positive, 66.66% with unchanged and 5.55% with negative volume. In the large space group these numbers were respectively 21.21%, 27.27%, and 51.51%. ConclusionsThere is significant variability on pleural space volume. However, pleural volume remains unchanged in many cases. Besides that, more than half patients with initial large space coursed with relevant reduction. Finally, patients with initial small space presented a greater chance of clinical success.
- Safety and Systemic Consequences of Pleurodesis with Three Different Doses of Silver Nitrate in Patients with Malignant Pleural Effusion(2015) TERRA, Ricardo Mingarini; BELLATO, Renato Tavares; TEIXEIRA, Lisete Ribeiro; CHATE, Rodrigo Caruso; PEGO-FERNANDES, Paulo ManuelBackground: Silver nitrate (SN) is an alternative to talc pleurodesis in patients with malignant pleural effusion (MPE). Nevertheless, SN complications have not been thoroughly investigated so far. Objective: To evaluate frequent adverse events (AE) of SN treatment at three different doses for pleurodesis in patients with MPE. The secondary objective was to evaluate systemic inflammation, efficacy and quality of life in these patients. Methods: A double-blind, randomized, clinical trial was conducted in patients with recurrent MPE at a tertiary university hospital. The study patients underwent pleural catheter insertion and were randomly assigned to one of the three pleurodesis groups treated with 30 ml 0.3%, 30 ml 0.5% or 60 ml 0.3% SN. Patients were discharged 3 days after the procedure, and returned to follow-up visits on days 10 and 30. During follow-up, AE, inflammatory markers, quality of life and CT scans were systematically assessed and documented. Results: Sixty patients (11 males and 49 females, median age 62.13 years) were included. Overall, 199 AE were observed, including 23 serious AE. Grade 1/2 metabolic AE, such as increases in creatinine and liver enzymes, were the most frequent. Grade 3/4 hypoxia was observed in 13 patients. Four patients died, 3 due to disease progression and in 1 patient death was possibly related to pleurodesis. C-reactive protein levels increased in a dose-dependent manner and peaked 48 h after pleurodesis. No significant difference was observed among groups regarding quality of life or clinical/radiological recurrence. Conclusion: Hypoxia was the most significant AE following SN pleurodesis; mild metabolic events were very common. SN instillation causes substantial dose-dependent systemic inflammatory responses. (C) 2015 S. Karger AG, Basel
- Ultrasound-guided intrapleural positioning of pleural catheters: influence on immediate lung expansion and pleurodesis in patients with recurrent malignant pleural effusion(2017) ARAUJO, Pedro Henrique Xavier Nabuco de; TERRA, Ricardo Mingarini; SANTOS, Thiago da Silva; CHATE, Rodrigo Caruso; PAIVA, Antonio Fernando Lins de; PEGO-FERNANDES, Paulo Manuel
conferenceObject What Happens to the Pleural Space Affected by Malignant Effusion after Bedside Pleurodesis?(2015) TERRA, Ricardo M.; ARAUJO, Pedro N.; SANTOS, Thiago S.; CHATE, Rdrigo C.; PAIVA, Antonio L.; PEGO-FERNANDES, Paulo M.conferenceObject RELATIONSHIP BETWEEN THE SUCCESS OF BEDSIDE PLEURODESIS AND PLEURAL ELASTANCE IN RECURRENT MALIGNANT PLEURAL EFFUSION(2014) TERRA, Ricardo Mingarini; ARAUJO, Pedro Henrique Xavier Nabuco De; PEGO-FERNANDES, Paulo; CHATE, Rodrigo Caruso- What Happens to the Pleural Space Affected by Malignant Effusion After Bedside Pleurodesis?(2015) ARAUJO, Pedro de; TERRA, Ricardo; SANTOS, Thiago; CHATE, Rodrigo; PAIVA, Antonio Fernando; PEGO-FERNADES, Paulo