PAULO HILARIO NASCIMENTO SALDIVA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Patologia, Faculdade de Medicina - Docente
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/05 - Laboratório de Poluição Atmosférica Experimental, Hospital das Clínicas, Faculdade de Medicina - Líder
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/05 - Laboratório de Poluição Atmosférica Experimental, Hospital das Clínicas, Faculdade de Medicina - Líder
11 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 11
bookPart Câncer e meio ambiente(2013) SALDIVA, Paulo Hilário Nascimento- Humidification and mucus transport in critical patients: Clinical and therapeutic implications(2012) NAKAGAWA, N. K.; NASCIMENTO, J. A.; NICOLA, M. L.; SALDIVA, P. H. N.An adult man inhales more than 12,000 l of air per day, which may contain particles and microorganisms. The epithelium of the conducting airways, from the nose to the bronchioli, are anatomically and physiologically designed to protect the alveoli by providing clean, warmed and fully saturated air at this level, where an efficient gas exchange must occur, and by providing specific defense mechanisms, such as trapping particles and microorganisms in the mucus and mucociliary transport of these agents in the direction of the oropharynx, where they will be swallowed or expectorated. Mucociliary transport (MCT) is an important respiratory defense mechanism, which efficiency depends on the equilibrium among three major components: ciliary beating, airway surface liquid (the periciliary liquid and mucus), and the interaction between cilia and mucus. In the intensive care unit (ICU) and emergency department, many factors can increase the risks of mucus transport dysfunction. Among them, artificial inspired air conditioning is a basic factor with physiological and clinical impact in critically ill patients. © Springer-Verlag Berlin Heidelberg 2012.
bookPart Envelhecimento populacional e as mudanças ambientais: poluição sonora(2015) OLIVEIRA, Rafaela Sanches de; BUSSE, Alexandre Leopold; SALDIVA, Paulo Hilário NascimentobookPart Paulo Hilário Nascimento Saldiva(2020) SALDIVA, Paulo Hilário Nascimento- How Environmental and Air Pollution Disrupt Spermatogenesis and Male Reproductive Health: A Mechanistic Approach(2018) HALLAK, J.; VERAS, M. M.; SALDIVA, P. H. N.Man is a masterpiece and is intimately linked to the environment from an evolutionary standpoint. The equation phenotype = genotype + environment that many of us learned at high school is just as relevant today, particularly in industrialized and polluted areas around the globe. © 2018 Elsevier Inc. All rights reserved.
bookPart Doenças respiratórias relacionadas com trabalho(2013) ALGRANTI, Eduardo; CAPITANI, Eduardo Mello de; CARNEIRO, Ana Paula Scalia; SALDIVA, Paulo Hilário Nascimento; MENDONçA, Elizabete Medina Coeli- How Environmental and Air Pollution Disrupt Spermatogenesis and Male Reproductive Health(2017) HALLAK, J.; VERAS, M. M.; SALDIVA, P. H. N.Man is a masterpiece and is intimately linked to the environment from an evolutionary standpoint. The equation phenotype=genotype+environment that many of us learned at high school is just as relevant today, particularly in industrialized and polluted areas around the globe. © 2018 Elsevier Inc. All rights reserved.
- Guidelines for Evaluation of Reproductive and Developmental Endpoints(2014) VERAS, Mariana M.; COSTA, Natália S.X.; SALDIVA, Paulo H.N.The objective of this chapter is to orientate readers to the approaches used to plan and conduct an experimental study for the evaluation of female reproductive and developmental toxicity endpoints using mice as models. The protocol presented here is focused on the evaluation of female reproductive performance endpoints such as gonadal function, mating behavior, conception, development of the conceptus, and parturition that may be altered as a result of pregestational and gestational exposure to any substance.
bookPart Poluição ambiental e doença cardiovascular(2016) SANTOS, Ubiratan; SALDIVA, Paulo- Pregnancy Alterations from Environmental Pollutants(2014) VERAS, Mariana M.; COSTA, Natália S.X.; SALDIVA, Paulo H.N.The objective of this chapter is to present briefly to readers that environmental pollutants that we contact in our daily life affect reproductive health and, in particular, produce adverse effects on fertility, pregnancy outcomes, and fetal health and development. Air pollution was emphasized air pollutants because nearly half of the world’s human population (3.5 billion) are living in urban areas with low to high levels of air pollution. Epidemiological and experimental evidences are described.