JEANNE DA ROSA OITICICA RAMALHO

(Fonte: Lattes)
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/32 - Laboratório de Otorrinolaringologia, Hospital das Clínicas, Faculdade de Medicina

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  • article 0 Citação(ões) na Scopus
    White noise effect on listening effort among patients with chronic tinnitus and normal hearing thresholds
    (2024) OITICICA, Jeanne; VASCONCELOS, Laura G. E.; HORIUTI, Mirella B.
    Objective: This study investigated the effects of WN on LE in subjects with chronic tinnitus and normal hearing thresholds. The study was a prospective, non-randomized, before-and-after, intra-participant intervention. Methods: Twenty-five subjects performed the following tests: conventional and high-frequency audiometry, acuphenometry, screening questionnaires for depression and anxiety symptoms, Tinnitus Handicap Inventory (THI), Montreal Cognitive Assessment, and high WM test from the Working Memory Assessment Battery, Federal University of Minas Gerais (WMAB) as the LE measure in two conditions: No Added Noise (NAN) and with Added Noise (AN). Results: Seventeen participants (68%) performed better on AN condition. Data analysis revealed a 45% improvement in the WMAB total span count on AN setting, with a significant p value (p = 0.001). Conclusion: The subgroup of participants without traces of anxiety symptoms, up to mild traces of depressive symptoms, having unilateral tinnitus, and a THI level up to grade 2, had improved WM performance in the presence of WN, which suggests a release of cognitive resources and less auditory effort under these combined conditions. Evidence level: 4. (c) 2023 Associac,ao Brasileira de Otorrinolaringologia e Cirurgia C ' ervico-Facial.
  • article 0 Citação(ões) na Scopus
    Generation of four induced pluripotent stem cells lines from PBMC of the DFNA58 family members: Two hearing-impaired duplication carriers (USPi006-A e USPi007-A) and two normal-hearing noncarriers (USPi004-A and USPi005-A)
    (2023) KOBAYASHI, Gerson S.; VIEIRA-SILVA, Gleiciele A.; VARELLA-BRANCO, Elisa; MOREIRA, Danielle P.; KITAJIMA, Joao Paulo F. W.; HEMZA, Claudia R. M. L.; MINGRONI-NETTO, Regina C.; LOJUDICE, Fernando H.; OITICICA, Jeanne; BENTO, Ricardo F.; BATISSOCO, Ana C.; LEZIROVITZ, Karina
    The DFNA58 locus contains a genomic duplication involving three protein-coding genes (CNRIP1, PLEK, and PPP3R1 & PRIME;s exon 1) and other uncharacterized lncRNA genes (LOC101927723, LOC107985892 and LOC102724389). To clarify the role of these genes in hearing and precisely determine their role in hearing loss, four iPSC lines were generated from two carriers and two noncarriers of the duplication.