RENATO ANGHINAH
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
9 resultados
Resultados de Busca
Agora exibindo 1 - 9 de 9
- Evaluation of patients with Alzheimer's disease before and after dental treatment(2014) ROLIM, Thais de Souza; FABRI, Gisele Maria Campos; NITRINI, Ricardo; ANGHINAH, Renato; TEIXEIRA, Manoel Jacobsen; SIQUEIRA, Jose Tadeu T. de; CESARI, Jose Augusto Ferrari; SIQUEIRA, Silvia Regina Dowgan Tesseroli deOral infections may play a role in Alzheimer's disease (AD). Objective: To describe the orofacial pain, dental characteristics and associated factors in patients with Alzheimer's Disease that underwent dental treatment. Method: 29 patients with mild AD diagnosed by a neurologist were included. They fulfilled the Mini Mental State Exam and Pfeffer's questionnaire. A dentist performed a complete evaluation: clinical questionnaire; research diagnostic criteria for temporomandibular disorders; McGill pain questionnaire; oral health impact profile; decayed, missing and filled teeth index; and complete periodontal investigation. The protocol was applied before and after the dental treatment. Periodontal treatments (scaling), extractions and topic nystatin were the most frequent. Results: There was a reduction in pain frequency (p=0.014), mandibular functional limitations (p=0.011) and periodontal indexes (p<0.05), and an improvement in quality of life (p=0.009) and functional impairment due to cognitive compromise (p<0.001) after the dental treatment. Orofacial complaints and intensity of pain also diminished. Conclusion: The dental treatment contributed to reduce co-morbidities associated with AD and should be routinely included in the assessment of these patients.
conferenceObject CORRELATION BETWEEN CHANGES IN GREY AND WHITE MATTER RADIODENSITY WITH PROGNOSIS AFTER CRANIOPLASTY(2014) OLIVEIRA, Arthur Maynart Pereira; AMORIM, Robson Luis Oliveira de; PAIVA, Wellingson Silva; ANDRADE, Almir Ferreira de; PASCHOAL JUNIOR, Fernando Mendes; BOR-SENG-SHU, Edson; COELHO, Fernanda; GATTAS, Gabriel Scarabotolo; ANGHINAH, Renato; TEIXEIRA, Manoel JacobsenconferenceObject MORPHOLOGICAL CHANGES ON CORTICAL SURFACE AND THEIR CORRELATION OF WITH NEUROLOGICAL OUTCOME IN PATIENTS WITH BONE DEFECTS AFTER DECOMPRESSIVE CRANIECTOMY(2014) OLIVEIRA, Arthur Maynart Pereira; AMORIM, Robson Luis Oliveira de; PAIVA, Wellingson Silva; ANDRADE, Almir Ferreira de; PASCHOAL JUNIOR, Fernando Mendes; BOR-SENG-SHU, Edson; COELHO, Fernanda; GATTAS, Gabriel Scarabotolo; ANGHINAH, Renato; TEIXEIRA, Manoel JacobsenconferenceObject WHAT CAN WE REALLY EXPECT OF CEREBRAL BLOOD FLOW AFTER CRANIOPLASTY?(2014) OLIVEIRA, Arthur Maynart Pereira; AMORIM, Robson Luis Oliveira de; PAIVA, Wellingson Silva; ANDRADE, Almir Ferreira de; PASCHOAL JUNIOR, Fernando Mendes; BOR-SENG-SHU, Edson; COELHO, Fernanda; GATTAS, Gabriel Scarabotolo; ANGHINAH, Renato; TEIXEIRA, Manoel Jacobsen- Oral Infections and Orofacial Pain in Alzheimer's Disease: A Case-Control Study(2014) ROLIM, Thais de Souza; FABRI, Gisele Maria Campos; NITRINI, Ricardo; ANGHINAH, Renato; TEIXEIRA, Manoel Jacobsen; SIQUEIRA, Jose Tadeu T. de; CESTARI, Jose Augusto Ferrari; SIQUEIRA, Silvia Regina Dowgan T. deBackground: Dental infections are frequent and have recently been implicated as a possible risk factor for Alzheimer's disease (AD). Despite a lack of studies investigating orofacial pain in this patient group, dental conditions are known to be a potential cause of pain and to affect quality of life and disease progression. Objectives: To evaluate oral status, mandibular function and orofacial pain in patients with mild AD versus healthy subjects matched for age and gender. Methods: Twenty-nine patients and 30 control subjects were evaluated. The protocol comprised a clinical questionnaire and dental exam, research diagnostic criteria for temporomandibular disorders, the McGill Pain Questionnaire, the decayed, missing, and filled teeth index, and included a full periodontal evaluation. AD signs and symptoms as well as associated factors were evaluated by a trained neurologist. Results: A higher prevalence of orofacial pain (20.7%, p < 0.001), articular abnormalities in temporomandibular joints (p < 0.05), and periodontal infections (p = 0.002) was observed in the study group compared to the control group. Conclusion: Orofacial pain and periodontal infections were more frequent in patients with mild AD than in healthy subjects. Orofacial pain screening and dental and oral exams should be routinely performed in AD patients in order to identify pathological conditions that need treatment thus improving quality of life compromised due to dementia.
- Traumatic Brain Injury Research in Brazil: A Bibliometric Study(2016) AMORIM, Robson Luis; TEIXEIRA, Saulo Araujo; SILVA-NETO, Sergio Goncalves; ANGHINAH, Renato; TEIXEIRA, Manoel Jacobsen; ANDRADE, Almir Ferreira de; PAIVA, Wellingson SilvaTraumatic brain injury (TBI) is responsible for high rates of morbidity and mortality, constituting an important public health problem throughout the world. Improving medical research on systemic trauma is a critical issue to understand its impact and develop strategies for prevention and treatment. This paper presents an overview of medical research performed in Brazil about TBI comparing it with the production on the same topic with other countries and with publications about different neurological and non-neurological diseases. It is possible to notice that Brazil has a deficiency in the scientific production on TBI given its importance. Greater integration between the research centers could help meliorate the production and quality of the papers and encourage further studies on the theme, in the quest to minimize the shortage of publications that can be seen today.
- Functional improvements associated with cranioplasty after stroke and traumatic brain injury: a cohort study(2023) COELHO, F.; NOLETO, G. S.; SOLLA, D. J. F.; MARTINS, P. N.; ANDRADE, A. F.; TEIXEIRA, M. J.; PAIVA, W. S.; ANGHINAH, R.Objective: Decompressive craniectomy is part of the acute management of several neurosurgical illnesses, and is commonly followed by cranioplasty. Data are still scarce on the functional and cognitive outcomes following cranioplasty. We aim to evaluate these outcomes in patients who underwent cranioplasty following traumatic brain injury (TBI) or stroke. Methods: n this prospective cohort, we assessed 1-month and 6-month neuropsychological and functional outcomes in TBI and stroke patients who underwent cranioplasty at a Brazilian tertiary center. The primary outcome was the change in the Digits Test at 1 and 6 months after cranioplasty. Repeated measures general linear models were employed to assess the patients' evolution and interactions with baseline characteristics. Effect size was estimated by the partial eta(2). Results: A total of 20 TBI and 14 stroke patients were included (mean age 42 +/- 14 years; 52.9% male; average schooling 9.5 +/- 3.8 years; 91.2% right-handed). We found significant improvements in the Digits Tests up to 6 months after cranioplasty (p = 0.004, partial eta(2) = 0.183), as well as in attention, episodic memory, verbal fluency, working memory, inhibitory control, visuoconstructive and visuospatial abilities (partial eta 2 0.106-0.305). We found no interaction between the cranioplasty effect and age, sex or schooling. Patients submitted to cranioplasty earlier (<1 year) after injury had better outcomes. Conclusion: Cognitive and functional outcomes improved after cranioplasty following decompressive craniectomy for stroke or TBI. This effect was consistent regardless of age, sex, or education level and persisted after 6 months. Some degree of spontaneous improvement might have contributed to the results.
conferenceObject Effects of cranioplasty in cerebral blood flow(2015) PAIVA, Wellingson Silva; OLIVEIRA, Arthur; AMORIM, Robson; BOR-SENG-SHU, Edson; ANGHINAH, Renato; ANDRADE, Almir; TEIXEIRA, Manoel- Comprehensive cognitive and cerebral hemodynamic evaluation after cranioplasty(2014) COELHO, Fernanda; OLIVEIRA, Arthur Maynart; PAIVA, Wellingson Silva; FREIRE, Fabio Rios; CALADO, Vanessa Tome; AMORIM, Robson Luis; NEVILLE, Iuri Santana; ANDRADE, Almir Ferreira de; BOR-SENG-SHU, Edson; ANGHINAH, Renato; TEIXEIRA, Manoel JacobsenDecompressive craniectomy is an established procedure to lower intracranial pressure and can save patients' lives. However, this procedure is associated with delayed cognitive decline and cerebral hemodynamics complications. Studies show the benefits of cranioplasty beyond cosmetic aspects, including brain protection, and functional and cerebrovascular aspects, but a detailed description of the concrete changes following this procedure are lacking. In this paper, the authors report a patient with trephine syndrome who underwent cranioplasty; comprehensive cognitive and cerebral hemodynamic evaluations were performed prior to and following the cranioplasty. The discussion was based on a critical literature review.