SALMA ROSE IMANARI RIBEIZ
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Validation of a treatment algorithm for major depression in an older Brazilian sample(2013) RIBEIZ, Salma R. I.; AVILA, Renata; MARTINS, Camila B.; MOSCOSO, Marco A. A.; STEFFENS, David C.; BOTTINO, Cassio M. C.Objective The aim of this study was to investigate the effectiveness of a modified version of the Duke Somatic Algorithm Treatment for Geriatric Depression (STAGED) in a Brazilian sample of older patients with major depression. Besides, we aimed to investigate possible baseline predictive factors for remission in this sample. Methods Sixty-seven depressed individuals were treated according to STAGED over 24 weeks in a prospective cohort design with follow-up. All patients had criteria for major depression and were at least 60 years of age at baseline enrollment. Results During this follow-up, 56 patients could be classified in remitted or not remitted group, 42.85% reached remission, and 57.14% did not reach remission. These results are even better than those found in the original study, probably due to the lower baseline depression severity of our sample. When baseline characteristics were compared between remitted and not remitted groups, scores of Mini Mental State Examination and Cambridge Cognitive Examination (CAMCOG) were the only variables with statistical significant difference (p<0.05) between groups. Logistic regression analysis was carried out to try to predict remission and statistical significance (p<0.05) was found only for baseline MMSE scores. It may mean that patients with mixed cognitive disorders and mood disorders have a worse course of depression. Conclusions This version of STAGED seems to be a useful strategy for treatment of depression in late life. Baseline general cognitive performance might be useful to predict remission of depression in older patients with mild to moderate depression. Further research with different population characteristics should be conducted in order to evaluate its usefulness and feasibility in different settings.
conferenceObject Depressive symptoms in older primary care patients: Results of the ""prevention and treatment of depression in elderly"" study in Brazil(2015) BOTTINO, Cassio M. C.; RIBEIZ, Salma; BASSOLI, Lucas; ALEXANDRINO-SILVA, Clovis- Effect of temporal lobe structure volume on memory in elderly depressed patients(2011) AVILA, Renata; RIBEIZ, Salma; DURAN, Fabio L. S.; ARRAIS, Jony P. J.; MOSCOSO, Marco A. A.; BEZERRA, Diana M.; JALUUL, Omar; CASTRO, Claudio C.; BUSATTO, Geraldo F.; BOTTINO, Cassio M. C.Objective: To compare the volume of the hippocampus and parahippocampal gyrus in elderly individuals with and without depressive disorders, and to determine whether the volumes of these regions correlate with scores on memory tests. Method: Clinical and demographic differences, as well as differences in regional gray matter volumes, were assessed in 48 elderly patients with depressive disorders and 31 control subjects. Brain (structural MRI) scans were processed using statistical parametric mapping and voxel-based morphometry. Cognitive tests were administered to subjects in both groups. Results: There were no between-group gray matter volume differences in the hippocampus or parahippocampal gyrus. In the elderly depressed group only, the volume of the left parahippocampal gyrus correlated with scores on the delayed naming portion of the visual verbal learning test. There were also significant direct correlations in depressed subjects between the volumes of the left hippocampus, right and left parahippocampal gyrus and immediate recall scores on verbal episodic memory tests and visual learning tests. In the control group, there were direct correlations only between overall cognitive performance (as assessed with the MMSE) and the volume of right hippocampus, and between the total score on the visual verbal learning test and the volume of the right and left parahippocampal gyrus. Conclusions: These findings highlight different patterns of relationship between cognitive performance and volumes of medial temporal structures in depressed individuals and healthy elderly subjects. The direct correlation between delayed visual verbal memory recall scores with left parahippocampal volumes specifically in elderly depressed individuals provides support to the view that depression in elderly populations may be a risk factor for dementia.
conferenceObject Physical activity and depressive symptoms in the elderly: A population-based study(2015) ALEXANDRINO-SILVA, Clovis; RIBEIZ, Salma; BASSOLLI, Lucas; BOTTINO, Cassio- Psychotic symptoms in older people without dementia from a Brazilian community-based sample(2015) SOARES, Walter Barbalho; RIBEIZ, Salma Rose I.; BASSITT, Debora P.; OLIVEIRA, Melaine C. De; BOTTINO, Cassio M. C.BackgroundThe international prevalence of psychotic symptoms in older subjects without dementia varies from 0.9% to 8.0%. However, an analysis of these symptoms in developing countries has not been undertaken. AimsTo determine the prevalence and to correlate these symptoms with socioeconomic and clinical characteristics. MethodA community-based sample aged 60years and older was evaluated. Those who screened positive for dementia, cognitive and functional impairment or significant depressive symptoms were excluded, resulting in 1125 individuals. ResultsThe prevalence of psychotic symptoms was 9.1% (visual/tactile hallucinations, 7.8%; auditive hallucinations, 7.5%; persecutory delusions, 2.9%). Subjects with psychotic symptoms had lower Mini Mental State Examination and The Bayer Activities of Daily Living Scale scores, fewer years of schooling, belonged to lower socioeconomic classes compared with non-psychotic subjects, and 80% had clinical comorbidities. ConclusionsThe prevalence was in the upper range of international data. Significant relationships were found between psychotic symptoms and lower Mini Mental State Examination score, fewer years of schooling and lower socioeconomic class. Clinical comorbidity was also very frequent.
conferenceObject Depressive symptoms and cognition: Preliminary results from a population-based study(2015) BOTTINO, Cassio; RIBEIZ, Salma; ALEXANDRINO-SILVA, Clovis; BASSOLLI, Lucas