MARCONY RODRIGUES DE SANTHIAGO
Projetos de Pesquisa
Unidades Organizacionais
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
7 resultados
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bookPart Escrita científica(2015) SANTHIAGO, Marcony Rodrigues; MAIA, Maurício; JOSé JUNIOR, Newton KarabookPart Percentual de tecido alterado (PTA) - conceito e aplicabilidade(2022) SANTHIAGO, Marcony R.- The Role of Thyroid Gland Dysfunction in the Development of Keratoconus(2022) STIVAL, L. R. S.; GIACOMIN, N. T.; SANTHIAGO, M. R.The number of studies on the development of thyroid gland dysfunction and keratoconus highlights the multifactorial nature of the disease. Many factors seem to be related to keratoconus, such as genetic predisposition, inflammatory markers, environmental conditions, eye rubbing, and metabolic and structural changes, in addition to systemic diseases and hormonal changes. There seems to be evidence that hormonal changes caused by thyroid gland dysfunction are additional factors that, through influencing the corneal structure, could affect keratoconus progression. Thyroid hormones are regulated by the pituitary axis of the thyroid (HPT) and can be imbalanced, besides primary genetic defects, by activating factors that alter homeostasis such as pregnancy, thyroidectomy, or iodine therapy. In this chapter, we emphasize the scientific evidence related to thyroid hormones and the possible correlation to keratoconus. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
bookPart Estrutura e estilo de escrita do artigo científico: a maneira com que pesquisadores reconhecem seus pares(2015) JOSé JUNIOR, Newton Kara; SANTHIAGO, Marcony Rodrigues- Natural Progression of Keratoconus(2022) SANTHIAGO, M. R.Keratoconus is an asymmetrical and progressive bilateral corneal ectasia that usually begins in the second decade of life. The inflammatory process’s role in the corneal structural changes present in keratoconus has already been described by quantifying altered levels of inflammatory cytokines in the tear film. It is known that changes in the maximum keratometry value are significantly correlated with changes in the central and thinnest thickness of the cornea and the thinnest epithelial thickness. In general, the steepening and stromal thinning are accompanied by epithelial thinning at the keratoconus’ apex in its natural progression. In conclusion, we realize that many metrics are helpful in monitoring keratoconus. Progressions in 1 year above 1D of Kmax, 0.7 Kmean, thinning of 10 in the thinnest pachymetry, myopic variation in the SE of 0.75D, or loss of two or more lines of vision suggest advancement beyond the natural history, and corneal crosslinking (CXL) is recommended to interrupt the progression if vision is 20/25 or worse. Besides, it is advised to consider CXL in patients under 18 years of age at diagnosis, given the progression speed in this group, if the vision is 20/25 or worse. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
bookPart 0 Citação(ões) na Scopus International perspectives: Brazil(2013) MARCON, A.; SANTHIAGO, M. R.; NETTO, M. V.bookPart Bases da Terapêutica Ocular(2018) JOSé JUNIOR, Newton Kara; SANTHIAGO, Marcony Rodrigues; GOMES, Beatriz de Abreu Fiuza