VITOR EMER EGYPTO ROSA
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/64, Hospital das Clínicas, Faculdade de Medicina
LIM/64, Hospital das Clínicas, Faculdade de Medicina
10 resultados
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conferenceObject Predictors of 30-Day Outcomes After TAVR in Low-Flow, Low-Gradient Aortic Stenosis(2018) ROSA, Vitor E. E.; ECHEVERRI, Dario; SZTEJFMAN, Matias; JAIKEL, Luis A.; DAGER, Antonio; MALUENDA, Gabriel; ABUD, Marcelo; DALMONTE, Anibal; FUCHS, Felipe C.; SARMENTO-LEITE, Rogerio; PRATES, Paulo; ABIZAID, Alexandre; SIQUEIRA, Dimytri; CHARRY, Pablo; CHAUVET, Alejandro A.; TARASOUTCHI, Flavio; CURA, Fernando; RIBEIRO, Henrique B.- Post-Operative Prognostic Prediction of Different Myocardial Fibrosis Measures in Severe Aortic Valvular Heart Disease(2020) PIRES, Lucas J.; ROSA, Vitor E.; MORAIS, Thamara C.; SANTIS, Antonio S. de; FERNANDES, Joao Ricardo C.; BOER, Berta P.; ROSSI, Eduardo; LAVITOLA, Paulo D.; ROCHITTE, Carlos E.; NOMURA, Cesar H.; POMERANTZEFF, Pablo M.; TARASOUTCHI, Flavio
conferenceObject Low-flow Low-gradient Aortic Stenosis With Low Ejection Fraction: Does Myocardial Fibrosis Predict Recovery of Postoperative Ventricular Function?(2016) ROSA, Vitor E.; SAMPAIO, Roney O.; SANTIS, Antonio S. de; FERNANDES, Joao Ricardo C.; ACCORSI, Tarso A.; ROSA, Marcela E.; VIEIRA, Marcelo L.; MORAIS, Thamara C.; BELLO, Juliana H.; MATHIAS, Wilson; ROCHITTE, Carlos E.; POMERANTZEFF, Pablo M.; TARASOUTCHI, FlavioconferenceObject Short- and Long-term Outcomes After Surgical Aortic Valve Replacement in Patients With Classical Low-flow, Low-gradient Aortic Stenosis(2019) ROSA, Vitor E.; RIBEIRO, Henrique B.; SAMPAIO, Roney O.; MORAIS, Thamara C.; ROSA, Marcela E.; SANTIS, Antonio S. De; FERNANDES, Joao Ricardo C.; SPINA, Guilherme S.; VIEIRA, Marcelo L.; POMERANTZEFF, Pablo M.; ROCHITTE, Carlos E.; MATHIAS JR., Wilson; TARASOUTCHI, FlavioconferenceObject The External Validity of Prediction Models for Contrast-Induced Nephropathy After TAVI: Insights From the Brazilian TAVI Registry.(2018) ROSA, Vitor E. E.; CAMPOS, Carlos M.; BACELAR, Antonio; ABIZAID, Alexandre A. C.; MANGIONE, Jose A.; LEMOS, Pedro A.; ESTEVES, Vinicius; CARAMORI, Paulo; TARASOUTCHI, Flavio; BRITO JR., Fabio S.- Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus: A Randomized Clinical Trial(2024) RODES-CABAU, Josep; RIBEIRO, Henrique Barbosa; MOHAMMADI, Siamak; SERRA, Vicenc; AL-ATASSI, Talal; INIGUEZ, Andres; VILALTA, Victoria; NOMBELA-FRANCO, Luis; SANCHEZ, Jose Ignacio Saez de Ibarra; AUFFRET, Vincent; FORCILLO, Jessica; CONRADI, Lenard; URENA, Marina; MORIS, Cesar; MUNOZ-GARCIA, Antonio; PARADIS, Jean-Michel; DUMONT, Eric; KALAVROUZIOTIS, Dimitri; POMERANTZEFF, Pablo Maria; ROSA, Vitor Emer Egypto; LOPES, Mariana Pezzute; SUREDA, Carles; DIAZ, Victor Alfonso Jimenez; GIULIANI, Carlos; AVVEDIMENTO, Marisa; PELLETIER-BEAUMONT, Emilie; PIBAROT, PhilippeBACKGROUND: The optimal treatment in patients with severe aortic stenosis and small aortic annulus (SAA) remains to be determined. This study aimed to compare the hemodynamic and clinical outcomes between transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with a SAA. METHODS: This prospective multicenter international randomized trial was performed in 15 university hospitals. Participants were 151 patients with severe aortic stenosis and SAA (mean diameter <23 mm) randomized (1:1) to TAVR (n=77) versus SAVR (n=74). The primary outcome was impaired valve hemodynamics (ie, severe prosthesis patient mismatch or moderate-severe aortic regurgitation) at 60 days as evaluated by Doppler echocardiography and analyzed in a central echocardiography core laboratory. Clinical events were secondary outcomes. RESULTS: The mean age of the participants was 75.5 +/- 5.1 years, with 140 (93%) women, a median Society of Thoracic Surgeons predicted risk of mortality of 2.50% (interquartile range, 1.67%-3.28%), and a median annulus diameter of 21.1 mm (interquartile range, 20.4-22.0 mm). There were no differences between groups in the rate of severe prosthesis patient mismatch (TAVR, 4 [5.6%]; SAVR, 7 [10.3%]; P=0.30) and moderate-severe aortic regurgitation (none in both groups). No differences were found between groups in mortality rate (TAVR, 1 [1.3%]; SAVR, 1 [1.4%]; P=1.00) and stroke (TAVR, 0; SAVR, 2 [2.7%]; P=0.24) at 30 days. After a median follow-up of 2 (interquartile range, 1-4) years, there were no differences between groups in mortality rate (TAVR, 7 [9.1%]; SAVR, 6 [8.1%]; P=0.89), stroke (TAVR, 3 [3.9%]; SAVR, 3 [4.1%]; P=0.95), and cardiac hospitalization (TAVR, 15 [19.5%]; SAVR, 15 [20.3%]; P=0.80). CONCLUSIONS: In patients with severe aortic stenosis and SAA (women in the majority), there was no evidence of superiority of contemporary TAVR versus SAVR in valve hemodynamic results. After a median follow-up of 2 years, there were no differences in clinical outcomes between groups. These findings suggest that the 2 therapies represent a valid alternative for treating patients with severe aortic stenosis and SAA, and treatment selection should likely be individualized according to baseline characteristics, additional anatomical risk factors, and patient preference. However, the results of this study should be interpreted with caution because of the limited sample size leading to an underpowered study, and need to be confirmed in future larger studies.
conferenceObject Correlation between Topographic Distribution of Aortic Valve Calcium and Hemodynamic Repercussion in Aortic Stenosis(2013) SANTIS, Antonio S. de; TARASOUTCHI, Flavio; SPINA, Guilherme; ROSA, Vitor; ACCORSI, Tarso; FERNANDES, Joao; NOMURA, Cesar; VIEIRA, Marcelo; SAMPAIO, Roney; GRINBERG, MaxconferenceObject Relationship Between Biomarkers and Different Types of Myocardial Fibrosis in Severe Aortic Valvular Heart Disease(2020) PIRES, Lucas J.; ROSA, Vitor E.; MORAIS, Thamara C.; SANTIS, Antonio S. de; FERNANDES, Joao Ricardo C.; BOER, Berta P.; ROSSI, Eduardo; LAVITOLA, Paulo D.; ROCHITTE, Carlos E.; NOMURA, Cesar H.; POMERANTZEFF, Pablo M.; TARASOUTCHI, FlavioconferenceObject Predictors of 1-Year Mortality After Surgical Aortic Valve Replacement in Patients With Classical Low-Flow, Low-Gradient Aortic Stenosis.(2018) ROSA, Vitor E. E.; RIBEIRO, Henrique B.; SAMPAIO, Roney O.; MORAIS, Thamara C.; ROSA, Marcela E. E.; SANTIS, Antonio S. A. I Antonio de; FERNANDES, Joao Ricardo C.; VIEIRA, Marcelo L. C.; POMERANTZEFF, Pablo M. A.; ROCHITTE, Carlos E.; JR, Wilson Mathias; TARASOUTCHI, FlavioconferenceObject Prognostic Significance of Elevated Troponin I After Valve Heart Surgery(2015) ARAGAO, Roberto C.; SAMPAIO, Roney O.; BITTENCOURT, Marcio S.; LOPES, Antonio S.; ACCORSI, Tarso A.; ROSA, Vitor E.; FERNANDES, Joao R.; SPINA, Guilherme S.; NAJJAR, Ludhmila A.; TARASOUTCHI, Flavio