THIAGO BITAR MORAES BARROS

Índice h a partir de 2011
4
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico

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  • article 6 Citação(ões) na Scopus
    Semantic and psychometric validation of the Brazilian Portuguese version (PASE-P) of the Psoriatic Arthritis Screening and Evaluation questionnaire
    (2018) COSTA, Carolina Zorzanelli; GOLDENSTEIN-SCHAINBERG, Claudia; CARNEIRO, Sueli; RODRIGUES, Jose Joaquim; ROMITI, Ricardo; BARROS, Thiago Bitar Martins; MARTINS, Gladys; CARNEIRO, Jamile; GRYNSZPAN, Rachel; SAMPAIO, Ana Luisa; MENDONCA, Tania Maria Silva; SILVA, Carlos Henrique Martins; QURESHI, Abrar A.; PINTO, Rogerio de Melo Costa; RANZA, Roberto
    PASE (Psoriatic Arthritis Screening and Evaluation) was developed in the English language to screen for inflammatory arthritis among patients with psoriasis. It is 15 item self administered questionnaire with a score from 15 to 75. A higher score indicates a greater risk for inflammatory joint disease. The purpose of this study was to translate, adapt and validate this questionnaire into Brazilian Portuguese (PASE-P). METHODS: 465 patients diagnosed with psoriasis (158 with psoriatic arthritis confirmed by a rheumatologist according to the CASPAR criteria and 307 without) were evaluated in dermatology clinics. We performed the analysis of semantic equivalence in eight steps. For psychometric equivalence, we evaluated the data quality, reliability, construct validity, well-known groups and discriminant characteristics of the items, as well as a ROC curve to determine optimal PASE-P cutoff points in case identification and their sensitivity / specificity. The final version presented excellent reproducibility (CCI = 0.97) and reliability (Cronbach's alpha> 0.9). A cut-off point of 25 distinguished between patients with and without psoriatic arthritis, with sensitivity of 69.5 and specificity of 86.8. PASE-P proved to be culturally valid and reliable to screen for psoriatic arthritis in Brazilian patients with psoriasis.
  • article 37 Citação(ões) na Scopus
    Prevalence of Psoriatic Arthritis in a Large Cohort of Brazilian Patients with Psoriasis
    (2015) RANZA, Roberto; CARNEIRO, Sueli; QURESHI, Abrar A.; MARTINS, Gladys; RODRIGUES, Jose Joaquim; ROMITI, Ricardo; BARROS, Thiago Bitar M.; CARNEIRO, Jamille; SAMPAIO, Ana Luisa; GRYNSZPAN, Rachel; MARKUS, Juliana; PINTO, Rogerio Melo Costa; GOLDENSTEIN-SCHAINBERG, Claudia
    Objective. To determine the prevalence of psoriatic arthritis (PsA) in a large cohort of Brazilian patients with psoriasis (PsO) being seen at dermatology centers. Methods. A multicenter study was conducted in 4 university dermatology clinics. In each center, consecutive patients with confirmed diagnoses of PsO were evaluated by a rheumatologist. Individuals were classified as having PsA according to the ClASsification criteria for Psoriatic ARthritis (CASPAR). Laboratory tests and radiographs were performed, as needed, based on the clinical judgment of the rheumatologist. Results. A total of 524 patients with PsO were evaluated. The mean age was 48.5 +/- 14.5 years, 50% were women, and the mean PsO duration was 15.4 +/- 11.7 years. A diagnosis of PsA was documented in 175 patients (33%), of whom 49% were newly identified by the rheumatologist. Most individuals with PsA (72%) had peripheral involvement, 11% had isolated axial involvement, and 17% had both peripheral and axial involvement. Dactylitis occurred in 20% and clinical enthesitis in 30% of the patients. Laboratory and/or radiograph tests were necessary for a definitive diagnosis of PsA in 42 of 175 individuals (24%). Conclusion. In our study, one-third of Brazilian patients with PsO, followed in dermatology settings, were diagnosed with PsA by a rheumatologist. Almost half of subjects with PsA had no previous diagnosis. A collaboration between dermatologists and rheumatologists is greatly needed to establish earlier PsA diagnoses and adequate multidisciplinary management.