MARCELO VIVOLO AUN

(Fonte: Lattes)
Índice h a partir de 2011
15
Lattes
ResearcherID
ORCID
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina

Filtros

Limpar filtros

Configurações

Revista / Livro: Journal of Allergy and Clinical Immunology ×

Resultados de Busca

Agora exibindo 1 - 10 de 15
  • conferenceObject
    Inhaled corticoids in asthmatic patients: effect on body mass index and spirometry
    (2018) PACHECO, Rosilane dos Reis; ANDRADE, Mayra Coutinho; PEDROSO, Natalia Falci; TAKEJIMA, Priscila; AUN, Marcelo V.; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.
  • conferenceObject
    Esophagogastroduodenal Mucosal Behavior after Bronchial Challenge with House Dust Mites in Allergic Asthmatic Patients
    (2015) AGONDI, Rosana C.; NAVARRO-RODRIGUEZ, Tomas; BARBUTI, Ricardo; BISACCIONI, Carla; AUN, Marcelo Vivolo; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
  • conferenceObject
    Characterization of Asthmatic Patients with Vocal Cord Dysfunction
    (2013) AGONDI, Rosana C.; GALVAO, Violeta; AUN, Marcelo; BISACCIONI, Carla; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
    RATIONALE: The vocal cord dysfunction (VCD) is a syndrome characterized by paradoxical movement of the vocal folds that causes respiratory distress. Our goal is to analyze asthmatic patients with VCD. METHODS: This was an observational and cross-sectional study involving patients over 18 years of age who had been diagnosed with asthma according to the Global Initiative for Asthma guidelines. Eighty-five patients were analyzed. They were submitted to spirometry, and tested for total and specific IgE to aeroallergens (skin prick test and/or in vitro ). RESULTS: The mean age was 52.1 years, and 93% were female. Sixty- seven patients had moderate or severe persistent asthma. Spirometry was normal or showed mild obstructive respiratory disease in 81% of them. Spirometric alterations suggestive of VCD were observed in 24% of the patients. The mean serum total IgE was 303 IU/mL and the detection of specific IgE was present in 76% of them. Gastroesophageal reflux disease was observed in 65% of the patients. When classified according to gender, we found that men were younger, had higher total IgE and higher prevalence of specific IgE. CONCLUSIONS: There was a higher prevalence of the association asthma and VCD in women, suggesting that this association could be masked in men. However, we observed that the clinical characteristics were different between men and women. We found a high prevalence of atopy that could be another confounding factor. There was a weak association between asthma and spirometric severity classifications, suggesting a potential role for VCD in making difficult to the asthma control in some patients.
  • conferenceObject
    Bordetella Pertussis Whole-Cell Vaccine Inhibits Specific IgE, Inflammation and Airway Remodeling in a Murine Model of Asthma
    (2015) AUN, Marcelo Vivolo; ARANTES-COSTA, Fernanda; SARAIVA-ROMANHOLO, Beatriz Mangueira; ALMEIDA, Francine Maria; REGINA-BRUEGGERMANN, Thayse; MARTINS, Milton Arruda; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
  • conferenceObject
    Perioperative Anaphylaxis: Clinical Features of 51 Patients
    (2012) GARRO, L. S.; RODRIGUES, A. T.; RIBEIRO, M. R.; AUN, M. V.; KALIL, J.; MOTTA, A. A.; GIAVINA-BIANCHI, P.
    Rationale: Perioperative anaphylaxis is an important and life-threatening adverse reaction in clinical practice. We aimed to evaluate the prevalence and the etiology of perioperative anaphylaxis referred to an outpatient clinic specialized in adverse drug reactions (ADRs). Methods: We evaluated 806 patients with history of ADRs through the questionnaire “European Network for Drug Allergy” (ENDA) from October 2006 to June 2011. Patients with a history of perioperative anaphylaxis were selected. The diagnostic criteria for anaphylaxis were based on the World Allergy Organization Guidelines. Etiological investigation was made with skin tests for latex, neuromuscular blockers (NMBs), antibiotics, hypnotics, opioids and local anesthetics. Drug provocation tests (DPTs) for antibiotics, NSAIDs, local anesthetics and latex were also performed. Serum specific IgE was tested for antibiotics (Penicillin, Ampicillin and Amoxicillin) and latex. Results: We identified 51 (6%) patients with a history of perioperative anaphylaxis. Among them, 16 patients (31%) had hypersensitivity reactions with positive cutaneous test, 14 patients (27%) abandoned the investigation and 8 patients (16%) completed the investigation with all tests being negative. Currently 12 patients (23%) are still under investigation. The main cause of perioperative anaphylaxis was latex allergy (22%), followed by NMBs hypersensitivity (6%). Three patients had positive tests for two different agents. Conclusions: Latex allergy was the main cause of perioperative anaphylaxis in this study. The importance of testing all the possible agents involved was demonstrated by the occurrence of three cases with positive test for two agents.
  • conferenceObject
    Midazolam is a major cause of intraoperative immediate hypersensitivity reactions
    (2018) D'ONOFRIO, Ana Carolina; BORALLI, Cristiane Fernandes; PORTILHO, Nathalia Coelho; GARRO, Laila Sabino; RIBEIRO, Marisa Rosimeire; MAGALHAES, Manoela Crespo De; CAMPOS, Lucila; MOTTA, Antonio Abilio; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AUN, Marcelo V.
  • conferenceObject
    Incidence of Intraoperative Anaphylaxis in A University General Hospital in Brazil
    (2013) GARRO, Laila Sabino; CARMONA, Maria Jose Carvalho; SOARES, Iracy Silvia Correa; AUN, Marcelo Vivolo; RIBEIRO, Marisa Rosimeire; RODRIGUES, Adriana Teixeira; KALIL, Jorge; GIAVINA-BIANCHI, Pedro; MOTTA, Antonio Abilio
    RATIONALE: The epidemiology of intraoperative anaphylaxis is un-known in Brazil. We aimed to evaluate the incidence and clinical features of anaphylaxis during anesthesia in a University General Hospital in Sao Paulo, Brazil. METHODS: A cross-sectional, observational study analyzing data fromvoluntary notification sent by anesthesiologists, about occurrence of intraoperative anaphylaxis during the period between January and December 2010. The diagnostic criteria for anaphylaxis were based onthe World Allergy Organization Guidelines. We analyzed the incidence of intraoperative anaphylaxis, clinical features, severity of anaphylaxis, types of surgical procedures, classification of anesthetic risk (American Society of Anesthesiologists - ASA), culprit agent cited by the anesthesiologist and type of treatment provided. RESULTS: The incidence of intraoperative anaphylaxis was 69:10.000 surgeries. The mean age of patients with anaphylaxis was 36.7 years-old and 57% were women. The most common procedures associated with anaphylaxis were the abdominal non-vascular (17.1%) and urologic (17.1%) surgeries. Skin symptoms were the most prevalent (85.7%) and all patients who presented cardiovascular shock were classified as ASA II (42.9%) or ASA III (57.1%). Epinephrine was used preferentially in anaphylaxis grade 3 (72.7%), while a few patients with anaphylaxis grades 1 and 2 took the drug (2.1% and 16.7, respectively). The most commonly etiologic drugs cited by the anesthesiologists were the neuromuscular blocking agents (22.9%). CONCLUSIONS: Our incidence of intraoperative anaphylaxis was higher than in other studies reported in the literature. These data are a warning signal to encourage measures to reduce the incidence of these severe reactions.
  • conferenceObject
    New Associations Between HLA Genotypes and Asthma Phenotypes
    (2016) TAKEJIMA, Priscila Megumi; AGONDI, Rosana C.; RODRIGUES, Helcio; AUN, Marcelo Vivolo; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
  • conferenceObject
    Diagnosis and treatment of AERD: clinical practice realities
    (2018) DIAS, Gabriella Melo Fontes Silva; ASSIS, Joao Paulo de; ANDRADE, Mayra Coutinho; CASTRO, Raisa Borges; MOUCO, Claudia Castilho; ZANANDREA, Andressa; AUN, Marcelo V.; KALIL, Jorge; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.
  • conferenceObject
    Inhibition of Inflammation and Mucus Production By Bordetella Pertussis Whole-Cell Vaccine in a Murine Model of Allergic Rhinitis
    (2016) AUN, Marcelo Vivolo; ARANTES-COSTA, Fernanda; ALMEIDA, Francine Maria; BRUGGERMANN, Thayse Regina; SARAIVA-ROMANHOLO, Beatriz Mangueira; GENARO, Isabella S.; MARTINS, Milton Arruda; KALIL, Jorge; GIAVINA-BIANCHI, Pedro