DANIEL ARAUJO FERRAZ
Projetos de Pesquisa
Unidades Organizacionais
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
3 resultados
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- Fundus autofluorescence imaging: Fundamentals and clinical relevance(2014) SEPAH, Y. J.; AKHTAR, A.; HAFEEZ, Y.; NASIR, H.; PEREZ, B.; MAWJI, N.; SADIQ, M. A.; DEAN, D. J.; FERRA, D. A.; NGUYEN, Q. D.Fundus autofluorescence (FAF) is a relatively new, noninvasive imaging modality that has been developed over the past decade. The autofluorescence (AF) images are obtained through the use of confocal scanning laser ophthalmoscopy (cSLO). It uses the fluorescent properties of lipofuscin (LP) to generate images that provide information beyond that is acquired by utilizing more conventional imaging methods such as fluorescein angiography, fundus photography, and regular optical coherence tomography (OCT). FAF has been an area of interest in ophthalmic research for over 40 years. However, it has only recently become clinically relevant because of various important technological advances. FAF has proved to be helpful in understanding the pathophysiological mechanisms, diagnostics, and identification of predictive markers for disease progression and for monitoring of novel therapies. © 2014 by Taylor & Francis Group, LLC.
- Optical coherence tomography(2014) IBRAHIM, M. A.; SEPAH, Y. J.; BITTENCOURT, M. G.; LIU, H.; HANOUTL, M.; FERRAZ, D. A.; DO, D. V.; NGUYEN, Q. D.Optical coherence tomography (OCT) is widely used in imaging of biological tissues such as eye, skin, and most recently blood vessels. In this chapter, we will give a brief history of OCT and its development, especially during the most recent years. We will also discuss about the physical principles underlying the technology. The spectrum of OCT applications is expanding quickly to include new medical and industrial disciplines. However, in this chapter, we will focus on the applications of OCT in the ophthalmological field, more specifically, in retina. Lastly, we will briefly discuss newer developments in OCT technologies with focus on research topics and future directions of use in ocular diseases. © 2014 by Taylor & Francis Group, LLC.
- Scanning laser ophthalmoscope fundus perimetry: The microperimetry(2014) BITTENCOURT, M. G.; FERRAZ, D. A.; LIU, H.; HANOUT, M.; SEPAH, Y. J.; DO, D. V.; NGUYEN, Q. D.Visual perception is the ultimate outcome of a variety of discriminative functions of the visual system in which the macular function plays a great role. For many years, physicians relied on best-corrected visual acuity (VA) measurements and retinoscopy to assess macular dysfunction. It is well known, however, that VA cannot fully distinguish deterioration of macular function. Throughout the ophthalmic history, several clinical examinations were designed to aid in the assessment of the various aspects of the visual function. Some of them are still in use such as contrast sensitivity, reading speed, macular recovery function, low-luminance VA, and color acuity, among others. However, no other functional test has shown the same ability of localizing retinal function depression as perimetry does. © 2014 by Taylor & Francis Group, LLC.