ALFREDO LUIZ JACOMO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cirurgia, Faculdade de Medicina - Docente
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject Lymph nodes of the level VI: anatomic study of lymph nodes located between the recurrent laryngeal nerve and the right common carotid artery(2017) SALEH, Samir; HOJAIJ, Flavio; CAMARGO, Cristina; ITEZEROTE, Ana Maria; ANDRADE, Mauro; AKAMATSU, Flavia Emi; JACOMO, Alfredo Luiz- Description of a new experimental model skin flap for studying skin viability in rats(2014) CAMARGO, Cristina Pires; MARGARIDO, Nelson Fontana; GUANDELINI, Eduardo; VIEIRA, Guilherme Alexandre Barrucci; JACOMO, Alfredo Luiz; GEMPERLI, RolfPURPOSE: To describe a new experimental flap for studying skin viability in rats. METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups. RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001). CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.
- Syntopy of vagus nerve in the carotid sheath: A dissectional study of 50 cadavers(2019) HOJAIJ, Flavio; REBELO, Gabriela; AKAMATSU, Flavia; ANDRADE, Mauro; CAMARGO, Cristina; CERNEA, Claudio; JACOMO, AlfredoBackground Vagus nerve anatomical position inside the carotid sheath is not clear in the literature. Nevertheless, monitoring laryngeal nerves during thyroid surgeries may damage big vessels in the carotid sheath (jugular vein; carotid artery). This gap led to an unprecedent cross sectional study of vagus syntopy using the carotid artery as anatomical mark. Methods Fifty cadavers less than 24 hours postmortem were studied. The vagus nerve was spotted, reproducing the patterns performed in thyroidectomies. Results On the right side, vagus nerve was posterior to the common carotid artery in 64% of the cases. On the left side, it was anterior, in 68% of the dissections. Comparing both sides, there was no symmetry in this syntopy. No influence of ethnic or anthropometric characteristics was observed. Conclusion The vagus nerve is more frequently posterior to the common carotid artery on the right side and, anterior, on the left side. Level of Evidence 4
conferenceObject Lymph nodes of the level VI: anatomic study of lymph nodes located between the recurrent laryngeal nerve and the right common carotid artery(2017) SALEH, Samir; HOJAIJ, Flavio; CAMARGO, Cristina; ITEZEROTE, Ana Maria; ANDRADE, Mauro; AKAMATSU, Flavia Emi; JACOMO, Alfredo Luiz- Linfonodos do nível VI: estudo anatômico dos linfonodos localizados entre o nervo laríngeo recorrente e a artéria carótida comum direita.(2018) SALEH, Samir Omar; HOJAIJ, Flávio Carneiro; ITEZEROTI, Ana Maria; CAMARGO, Cristina Pires; SALEH, Kassem Samir; ANDRADE, Mauro Figueiredo Carvalho de; AKAMATSU, Flávia Emi; JACOMO, Alfredo LuizABSTRACT Objective: to describe the presence of lymph nodes and their relationships with demographic and anthropometric characteristics in a specific region, not yet described in anatomy compendiums, called by us Recurrent Carotid Recess (RCR) and located among the right recurrent laryngeal nerve, the right common carotid artery, and the right inferior thyroid artery. Methods: 32 right cervical regions were harvested from cadavers within 24 hours post-mortem. The fibro-fatty tissue of the RCR was resected and prepared with formalin fixation. It was then subjected to an increasing sequence of alcohols (70%, 80%, and 90%), subsequently to a solution of Xylol, and finally to a solution of Methyl Salicylate, respecting the time required for each step. The macroscopic study was carried out on the diaphanized piece, observing the presence or not of lymph nodes. When present, they were photographed and their measurements were gauged with a digital caliper. In the microscopic study, hematoxylin-eosin staining was used to confirm the lymph node. Results: the presence of lymph nodes was observed in 22 (68.75%) of the 32 specimens. The number of lymph nodes ranged from zero to six (mean of 1.56±0.29), per cadaver, and their mean size was 7.82mmx3.86mm (longitudinal x transversal diameters). Conclusion: the relationship between anthropometric data and presence of lymph nodes in the RCR (Fisher’s exact test) was significant for medium-height individuals (p=0.03) and also white ones (p=0.04).
- Botulinum toxin type A on cutaneous flap viability in diabetic and tobacco-exposed rats(2015) CAMARGO, Cristina Pires; JACOMO, Alfredo Luiz; BATTLEHNER, Claudia Naves; LEMOS, Miriam; SALDIVA, Paulo Hilario; MARTINS, Milton Arruda; MUNHOZ, Alexandre Mendonca; GEMPERLI, RolfPURPOSE: To investigate the effect of Botulinum toxin A (BoNTA) on skin flap viability in healthy, tobacco-exposed and diabetic rats. METHODS: Ninety male Wistar rats (250-300g) were randomly divided into six groups: control+saline (C1), control+BoNTA (C2), tobacco-exposed+saline (T1), tobacco-exposed+BoNTA (T2) diabetes+saline (D1) and diabetes+BoNTA (D2). A dorsal cutaneous flap (3x10cm) was performed. Survival area and total area of the flaps were measured. Lumen diameter, external arterial diameter and lumen/wall thickness ratio were recorded. RESULTS: Survival area increased in control group with BoNTA injection compared with control animals injected with saline (C2 x C1; 0.9 +/- 0.1 vs 0.67 +/- 0.15, p=0.001). A similar result was found in diabetes group injected with BontA (D2 x D1; 0.97 +/- 0.2 vs 0.61 +/- 0.24, p=0.018). No difference was observed in skin flap viability in tobacco-exposed groups (T2 x T1; 0.74 +/- 0.24 vs 0.64 +/- 0.21, p=0.871). Lumen diameter (p=0.004), external arterial diameter (p=0.0046,) and lumen/wall thickness ratio (p=0.003) were increased in diabetes+BoNTA-treated animals. This effect was not observed in control or in tobacco-exposed groups. CONCLUSIONS: Botulinum toxin A increased skin flap viability in control and diabetic rats on the seventh post-operative day. Increased lumen diameter, external arterial diameter, and lumen/wall thickness ratio were observed in the diabetes+BoNTA group. BoNTA had no effect in the tobacco-exposed group on the seventh postoperative day.