JOSE RIBAS MILANEZ DE CAMPOS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
12 resultados
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- Nationwide Cross-sectional Analysis of Endoscopic Thoracic Sympathectomy to Treat Hyperhidrosis Over 12 years in Brazil Epidemiology, Costs, and Mortality(2023) LOUZADA, Andressa Cristina Sposato; SILVA, Marcelo Fiorelli Alexandrino da; PORTUGAL, Maria Fernanda Cassino; TEIVELIS, Marcelo Passos; JERUSSALMY, Claudia Szlejf; AMARO, Edson; CAMPOS, Jose Ribas Milanez de; WOLOSKER, NelsonObjective:To analyze the number of endoscopic thoracic sympathectomies performed to treat hyperhidrosis in the Universal Public Health System of Brazil, the government reimbursements, and the in-hospital mortality rates. Background:Even though endoscopic thoracic sympathectomy has been widely performed for the definitive treatment of hyperhidrosis, no series reported mortality and there are no population-based studies evaluating its costs or its mortality rate. Methods:Data referring to endoscopic thoracic sympathectomy to treat hyperhidrosis between 2008 and 2019 were extracted from the database of the Brazilian Public Health System, which insures more than 160 million inhabitants. Results:Thirteen thousand two hundred one endoscopic thoracic sympathectomies to treat hyperhidrosis were performed from 2008 to 2019, with a rate of 68.44 procedures per 10 million inhabitants per year. There were 6 in-hospital deaths during the whole period, representing a mortality rate of 0.045%. The total expended throughout the years was U$ 6,767,825.14, with an average of U$ 512.68 per patient. Conclusions:We observed a rate of 68.44 thoracoscopic sympathectomies for hyperhidrosis' treatment per 10 million inhabitants per year. The inhospital mortality rate was very low, 0.045%, though not nil. To our knowledge, no published series is larger than ours and we are the first authors to formally report deaths after endoscopic thoracic sympathectomies to treat hyperhidrosis. Moreover, there is no other population-based study addressing costs and mortality rates of every endoscopic thoracic sympathectomy for the treatment of any site of hyperhidrosis in a given period.
bookPart Cirurgia do pneumotórax (pleurectomia parietal)(2023) SCHMIDT JR., Aurelino Fernandes; CAMPOS, José Ribas Milanez; GREGóRIO, Paulo Henrique PeitlbookPart Pectus carinatum: tratamento cirúrgico e/ou tratamento não invasivo?(2023) TEDDE, Miguel Lia; CAMPOS, José Ribas Milanez; SAVAZZI, Flavio Henrique; SOUSA, Vanessa MoreirabookPart Fixação dos arcos costais e do esterno no trauma torácico(2023) CAMPOS, José Ribas Milanez; MARIANI, Alessandro Wasum; TEDDE, Miguel Lia; LAURICELLA, Leticia Leone- Robot-assisted thoracoscopic surgery resection of a ground-glass nodule in the right middle lobe(2023) MINAMOTO, Fabio Eiti Nishibe; MENDES, Guilherme Falleiros; CAMPOS, Jose Ribas Milanez de; GARCIA, Rodrigo Gobbo; TERR, Ricardo Mingarini
bookPart Simpatectomia torácica unilateral ou bilateral simultânea(2023) CAMPOS, José Ribas Milanez; TEDDE, Miguel Lia; HAMILTON, Niura Noro; WOLOSKER, Nelson; KAUFFMAN, Paulo- A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining(2023) FERNEZLIAN, S. M.; BALDAVIRA, C. M.; SOUZA, M. L. F. de; FARHAT, C.; VILHENA, A. F. de; PEREIRA, J. C. N.; CAMPOS, J. R. M. de; TAKAGAKI, T.; BALANCIN, M. L.; AB'SABER, A. M.; CAPELOZZI, V. L.Nuclear proliferation marker MIB-1 (Ki-67) immunohistochemistry (IHC) is used to examine tumor cell proliferation. However, the diagnostic or prognostic value of the Ki-67 nuclear staining intensity and location, defined as nuclear gradient (NG), has not been assessed. This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC, PAD, and BDC. High intraobserver consistency and moderate interobserver agreement were achieved in the determination of Ki-67 NG in tumor specimens. NG1 and NG2 were lower in PTC than in PAD and BDC. Cox multivariate analysis of PTC after adjusting for age and number of metastatic lymph nodes showed that Ki-67 NG1 and NG2 significantly predicted clinical outcomes. The semi-automated method for quantification of Ki-67 nuclear immunostaining proposed in this study could become a valuable diagnostic and prognostic tool in PTC.
bookPart Fenda esternal: reconstrução do esterno com materiais biológicos(2023) CAMPOS, José Ribas Milanez; TEDDE, Miguel Lia; MACEDO, João Paulo C. de- Pectus Excavatum: Consensus and Controversies in Clinical Practice(2023) JANSSEN, Nicky; DAEMEN, Jean H. T.; POLEN, Elise J. van; COORENS, Nadine A.; JANSEN, Yanina J. L.; FRANSSEN, Aimee J. P. M.; HULSEWE, Karel W. E.; VISSERS, Yvonne L. J.; HAECKER, Frank -Martin; CAMPOS, Jose R. Milanez de; LOOS, Erik R. de; Chest Wall Int Grp Collaborator GrpBACKGROUND Pectus excavatum is the most common congenital anterior chest wall deformity. Currently, a wide variety of diagnostic protocols and criteria for corrective surgery are being used. Their use is predominantly based on local preferences and experience. To date, no guideline is available, introducing heterogeneity of care as observed in current daily practice. The aim of this study was to evaluate consensus and controversies regarding the diagnostic protocol, indications for surgical correction, and postoperative evaluation of pectus excavatum. METHODS The study consisted of 3 consecutive survey rounds evaluating agreement on different statements regarding pectus excavatum care. Consensus was achieved if at least 70% of participants provided a concurring opinion. RESULTS All 3 rounds were completed by 57 participants (18% response rate). Consensus was achieved on 18 of 62 statements (29%). Regarding the diagnostic protocol, participants agreed to routinely include conventional photog-raphy. In the presence of cardiac impairment, electrocardiography and echocardiography were indicated. Upon sus-picion of pulmonary impairment, spirometry was recommended. In addition, consensus was reached on the indications for corrective surgery, including symptomatic pectus excavatum and progression. Participants moreover agreed that a plain chest radiograph must be acquired directly after surgery, whereas conventional photography and physical ex-amination should both be part of routine postoperative follow-up. CONCLUSIONS Through a multiround survey, international consensus was formed on multiple topics to aid stan-dardization of pectus excavatum care. (Ann Thorac Surg 2023;116:191-9) & COPY; 2023 by The Society of Thoracic Surgeons.
bookPart Ressecção do primeiro arco costal videotoracoscópica e robótica(2023) MACEDO, João Paulo C. de; CAMPOS, José Ribas Milanez; MARIANI, Alessandro Wasum