LAURA HELENA SILVEIRA GUERRA DE ANDRADE
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica, Hospital das Clínicas, Faculdade de Medicina - Líder
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Undertreatment of people with major depressive disorder in 21 countries(2017) THORNICROFT, Graham; CHATTERJI, Somnath; EVANS-LACKO, Sara; GRUBER, Michael; SAMPSON, Nancy; AGUILAR-GAXIOLA, Sergio; AL-HAMZAWI, Ali; ALONSO, Jordi; ANDRADE, Laura; BORGES, Guilherme; BRUFFAERTS, Ronny; BUNTING, Brendan; ALMEIDA, Jose Miguel Caldas de; FLORESCU, Silvia; GIROLAMO, Giovanni de; GUREJE, Oye; HARO, Josep Maria; HE, Yanling; HINKOV, Hristo; KARAM, Elie; KAWAKAMI, Norito; LEE, Sing; NAVARRO-MATEU, Fernando; PIAZZA, Marina; POSADA-VILLA, Jose; GALVIS, Yolanda Torres de; KESSLER, Ronald C.Background Major depressive disorder (MDD) is a leading cause of disability worldwide. Aims To examine the: (a) 12-month prevalence of DSM-IV MDD; (b) proportion aware that they have a problem needing treatment and who want care; (c) proportion of the latter receiving treatment; and (d) proportion of such treatment meeting minimal standards. Method Representative community household surveys from 21 countries as part of the World Health Organization World Mental Health Surveys. Results Of 51 547 respondents, 4.6% met 12-month criteria for DSM-IV MDD and of these 56.7% reported needing treatment. Among those who recognised their need for treatment, most (71.1%) made at least one visit to a service provider. Among those who received treatment, only 41.0% received treatment that met minimal standards. This resulted in only 16.5% of all individuals with 12-month MDD receiving minimally adequate treatment. Conclusions Only a minority of participants with MDD received minimally adequate treatment: 1 in 5 people in high-income and 1 in 27 in low-/lower-middle-income countries. Scaling up care for MDD requires fundamental transformations in community education and outreach, supply of treatment and quality of services.
- Parent psychopathology and offspring mental disorders: results from the WHO World Mental Health Surveys(2012) MCLAUGHLIN, Katie A.; GADERMANN, Anne M.; HWANG, Irving; SAMPSON, Nancy A.; AL-HAMZAWI, Ali; ANDRADE, Laura Helena; ANGERMEYER, Matthias C.; BENJET, Corina; BROMET, Evelyn J.; BRUFFAERTS, Ronny; CALDAS-DE-ALMEIDA, Jose Miguel; GIROLAMO, Giovanni de; GRAAF, Ron de; FLORESCU, Silvia; GUREJE, Oye; HARO, Josep Maria; HINKOV, Hristo Ruskov; HORIGUCHI, Itsuko; HU, Chiyi; KARAM, Aimee Nasser; KOVESS-MASFETY, Viviane; LEE, Sing; MURPHY, Samuel D.; NIZAMIE, S. Haque; POSADA-VILLA, Jose; WILLIAMS, David R.; KESSLER, Ronald C.Background Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity. Aims To examine the associations of parent with respondent disorders. Method Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews. Results Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle-than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders. Conclusions Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.
- Role of common mental and physical disorders in partial disability around the world(2012) BRUFFAERTS, Ronny; VILAGUT, Gemma; DEMYTTENAERE, Koen; ALONSO, Jordi; ALHAMZAWI, Ali; ANDRADE, Laura Helena; BENJET, Corina; BROMET, Evelyn; BUNTING, Brendan; GIROLAMO, Giovanni de; FLORESCU, Silvia; GUREJE, Oye; HARO, Josep Maria; HE, Yanling; HINKOV, Hristo; HU, Chiyi; KARAM, Elie G.; LEPINE, Jean-Pierre; LEVINSON, Daphna; MATSCHINGER, Herbert; NAKANE, Yoshibumi; ORMEL, Johan; POSADA-VILLA, Jose; SCOTT, Kate M.; VARGHESE, Matthew; WILLIAMS, David R.; XAVIER, Miguel; KESSLER, Ronald C.Background Mental and physical disorders are associated with total disability, but their effects on days with partial disability (i.e. the ability to perform some, but not full-role, functioning in daily life) are not well understood. Aims To estimate individual (i.e. the consequences for an individual with a disorder) and societal effects (i.e. the avoidable partial disability in the society due to disorders) of mental and physical disorders on days with partial disability around the world. Method Respondents from 26 nationally representative samples (n=61 259, age 18+) were interviewed regarding mental and physical disorders, and day-to-day functioning. The Composite International Diagnostic Interview, version 3.0 (CIDI 3.0) was used to assess mental disorders; partial disability (expressed in full day equivalents) was assessed with the World Health Organization Disability Assessment Schedule in the CIDI 3.0. Results Respondents with disorders reported about 1.58 additional disability days per month compared with respondents without disorders. At the individual level, mental disorders (especially post-traumatic stress disorder, depression and bipolar disorder) yielded a higher number of days with disability than physical disorders. At the societal level, the population attributable risk proportion due to physical and mental disorders was 49% and 15% respectively. Conclusions Mental and physical disorders have a considerable impact on partial disability, at both the individual and at the societal level. Physical disorders yielded higher effects on partial disability than mental disorders.
- Premarital mental disorders and physical violence in marriage: cross-national study of married couples(2011) MILLER, E.; BRESLAU, J.; PETUKHOVA, M.; FAYYAD, J.; GREEN, J. Greif; KOLA, L.; SEEDAT, S.; STEIN, D. J.; TSANG, A.; VIANA, M. C.; ANDRADE, L. H.; DEMYTTENAERE, K.; GIROLAMO, G. de; HARO, J. M.; HU, C.; KARAM, E. G.; KOVESS-MASFETY, V.; TOMOV, T.; KESSLER, R. C.Backgroud Mental disorders may increase the risk of physical violence among married couples. Aims To estimate associations between premarital mental disorders and marital violence in a cross-national sample of married couples. Method A total of 1821 married couples (3642 individuals) from 11 countries were interviewed as part of the World Health Organization's World Mental Health Survey Initiative. Sixteen mental disorders with onset prior to marriage were examined as predictors of marital violence reported by either spouse. Results Any physical violence was reported by one or both spouses in 20% of couples, and was associated with husbands' externalising disorders (OR = 1.7, 95% Cl 1.2-2.3). Overall, the population attributable risk for marital violence related to premarital mental disorders was estimated to be 17.2%. Conclusions Husbands' externalising disorders had a modest but consistent association with marital violence across diverse countries. This finding has implications for the development of targeted interventions to reduce risk of marital violence.
- Trauma and psychotic experiences: transnational data from the World Mental Health Survey(2017) MCGRATH, John J.; SAHA, Sukanta; LIM, Carmen C. W.; AGUILAR-GAXIOLA, Sergio; ALONSO, Jordi; ANDRADE, Laura H.; BROMET, Evelyn J.; BRUFFAERTS, Ronny; ALMEIDA, Jose M. Caldas de; CARDOSO, Graca; GIROLAMO, Giovanni de; FAYYAD, John; FLORESCU, Silvia; GUREJE, Oye; HARO, Josep M.; KAWAKAMI, Norito; KOENEN, Karestan C.; KOVESS-MASFETY, Viviane; LEE, Sing; LEPINE, Jean-Pierre; MCLAUGHLIN, Katie A.; MEDINA-MORA, Maria E.; NAVARRO-MATEU, Fernando; OJAGBEMI, Akin; POSADA-VILLA, Jose; SAMPSON, Nancy; SCOTT, Kate M.; TACHIMORI, Hisateru; HAVE, Margreet ten; KENDLER, Kenneth S.; KESSLER, Ronald C.Background Traumatic events are associated with increased risk of psychotic experiences, but it is unclear whether this association is explained by mental disorders prior to psychotic experience onset. Aims To investigate the associations between traumatic events and subsequent psychotic experience onset after adjusting for post-traumatic stress disorder and other mental disorders. Method We assessed 29 traumatic event types and psychotic experiences from the World Mental Health surveys and examined the associations of traumatic events with subsequent psychotic experience onset with and without adjustments for mental disorders. Results Respondents with any traumatic events had three times the odds of other respondents of subsequently developing psychotic experiences (OR=3.1, 95% CI 2.7-3.7), with variability in strength of association across traumatic event types. These associations persisted after adjustment for mental disorders. Conclusions Exposure to traumatic events predicts subsequent onset of psychotic experiences even after adjusting for comorbid mental disorders.