LAURA HELENA SILVEIRA GUERRA DE ANDRADE

(Fonte: Lattes)
Índice h a partir de 2011
41
Lattes
ResearcherID
ORCID
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica, Hospital das Clínicas, Faculdade de Medicina - Líder

Filtros

Mostrar mais
Limpar filtros

Configurações

Assunto: epidemiology ×

Resultados de Busca

Agora exibindo 1 - 10 de 19
  • article 1852 Citação(ões) na Scopus
    Prevalence and Correlates of Bipolar Spectrum Disorder in the World Mental Health Survey Initiative
    (2011) MERIKANGAS, Kathleen R.; JIN, Robert; HE, Jian-Ping; KESSLER, Ronald C.; LEE, Sing; SAMPSON, Nancy A.; VIANA, Maria Carmen; ANDRADE, Laura Helena; HU, Chiyi; KARAM, Elie G.; LADEA, Maria; MEDINA-MORA, Maria Elena; ONO, Yutaka; POSADA-VILLA, Jose; SAGAR, Rajesh; WELLS, J. Elisabeth; ZARKOV, Zahari
    Context: There is limited information on the prevalence and correlates of bipolar spectrum disorder in international population-based studies using common methods. Objectives: To describe the prevalence, impact, patterns of comorbidity, and patterns of service utilization for bipolar spectrum disorder (BPS) in the World Health Organization World Mental Health Survey Initiative. Design, Setting, and Participants: Crosssectional, face-to-face, household surveys of 61 392 community adults in 11 countries in the Americas, Europe, and Asia assessed with the World Mental Health version of the World Health Organization Composite International Diagnostic Interview, version 3.0, a fully structured, lay-administered psychiatric diagnostic interview. Main Outcome Measures: Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) disorders, severity, and treatment. Results: The aggregate lifetime prevalences were 0.6% for bipolar type I disorder (BP-I), 0.4% for BP-II, 1.4% for subthreshold BP, and 2.4% for BPS. Twelve-month prevalences were 0.4% for BP-I, 0.3% for BP-II, 0.8% for subthreshold BP, and 1.5% for BPS. Severity of both manic and depressive symptoms as well as suicidal behavior increased monotonically from subthreshold BP to BP-I. By contrast, role impairment was similar across BP subtypes. Symptom severity was greater for depressive episodes than manic episodes, with approximately 74.0% of respondents with depression and 50.9% of respondents with mania reporting severe role impairment. Three-quarters of those with BPS met criteria for at least 1 other disorder, with anxiety disorders (particularly panic attacks) being the most common comorbid condition. Less than half of those with lifetime BPS received mental health treatment, particularly in low-income countries, where only 25.2% reported contact with the mental health system. Conclusions: Despite cross-site variation in the prevalence rates of BPS, the severity, impact, and patterns of comorbidity were remarkably similar internationally. The uniform increases in clinical correlates, suicidal behavior, and comorbidity across each diagnostic category provide evidence for the validity of the concept of BPS. Treatment needs for BPS are often unmet, particularly in low-income countries.
  • article 25 Citação(ões) na Scopus
    Twelve-month mental health service use in six countries of the Americas: A regional report from the World Mental Health Surveys
    (2020) BORGES, G.; AGUILAR-GAXIOLA, S.; ANDRADE, L.; BENJET, C.; CIA, A.; KESSLER, R. C.; OROZCO, R.; SAMPSON, N.; STAGNARO, J. C.; TORRES, Y.; VIANA, Maria Carmen; MEDINA-MORA, M. E.
    Aims. To provide cross-national data for selected countries of the Americas on service utilization for psychiatric and substance use disorders, the distribution of these services among treatment sectors, treatment adequacy and factors associated with mental health treatment and adequacy of treatment. Methods. Data come from data collected from 6710 adults with 12 month mental disorder surveys across seven surveys in six countries in North (USA), Central (Mexico) and South (Argentina, Brazil, Colombia, Peru) America who were interviewed 2001-2015 as part of the World Health Organization (WHO) World Mental Health (WMH) Surveys. DSM-IV diagnoses were made with the WHO Composite International Diagnostic Interview (CIDI). Interviews also assessed service utilization by the treatment sector, adequacy of treatment received and socio-demographic correlates of treatment. Results. Little over one in four of respondents with any 12 month DSM-IV/CIDI disorder received any treatment. Although the vast majority (87.1%) of this treatment was minimally adequate, only 35.3% of cases received treatment that met acceptable quality guidelines. Indicators of social-advantage (high education and income) were associated with higher rates of service use and adequacy, but a number of other correlates varied across survey sites. Conclusions. These results shed light on an enormous public health problem involving under-treatment of common mental disorders, although the problem is most extreme among people with social disadvantage. Promoting services that are more accessible, especially for those with few resources, is urgently needed.
  • article 16 Citação(ões) na Scopus
    Use of psychotropic medications in Sao Paulo Metropolitan Area, Brazil: pattern of healthcare provision to general population
    (2015) CAMPANHA, Angela Maria; SIU, Erica Rosanna; MILHORANCA, Igor Andre; VIANA, Maria Carmen; WANG, Yuan-Pang; ANDRADE, Laura Helena
    Purpose We estimate the proportion of psychotropic medication use (PMU) among adults in Sao Paulo Metropolitan Area, Brazil. We investigated whether socio-demographic factors, comorbidity, and disease severity influence PMU among individuals with psychiatric disorders. Methods Data are from the Sao Paulo Megacity Mental Health Survey, a cross-sectional, population-based study, the Brazilian branch of the World Mental Health Survey Initiative. Trained lay interviewers face-to-face assessed psychiatric disorders and PMU through the Composite International Diagnostic Interview. Respondents were asked about use of healthcare service and prescribed medications for mental disorders in the previous year. Information on PMU was collected for 2935 adult residents in the area and among those with disorders who received treatment. Results Around 6% of respondents reported PMU in the past year: hypnotics or sedatives were used by 3.7% and antidepressants by 3.5%. Among individuals with 12-month disorders, only 14% reported past year PMU. Gender, age, education, income, occupational status, comorbidity, and severity were significant predictors for PMU. Among those with 12-month DSM-IV disorders who obtained treatment in healthcare settings, almost 40% received medication only. Among those treated in specialty mental health service, around 23% received combination of medication and psychotherapy. Conclusion Our study has pointed out that the recent trend of access to mental healthcare in Brazil depicts unmet needs, characterized by a low prevalence of PMU among individuals with psychiatric disorders. Policies that improve appropriate access to prescribed drugs for those most in need are urgent public health priority.
  • article 44 Citação(ões) na Scopus
    The cross-national structure of mental disorders: results from the World Mental Health Surveys
    (2018) JONGE, Peter de; WARDENAAR, Klaas J.; LIM, Carmen C. W.; AGUILAR-GAXIOLA, Sergio; ALONSO, Jordi; ANDRADE, Laura Helena; BUNTING, Brendan; CHATTERJI, Somnath; CIUTAN, Marius; GUREJE, Oye; KARAM, Elie G.; LEE, Sing; MEDINA-MORA, Maria Elena; MOSKALEWICZ, Jacek; NAVARRO-MATEU, Fernando; PENNELL, Beth-Ellen; PIAZZA, Marina; POSADA-VILLA, Jose; TORRES, Yolanda; KESSLER, Ronald C.; SCOTT, Kate
    BackgroundThe patterns of comorbidity among mental disorders have led researchers to model the underlying structure of psychopathology. While studies have suggested a structure including internalizing and externalizing disorders, less is known with regard to the cross-national stability of this model. Moreover, little data are available on the placement of eating disorders, bipolar disorder and psychotic experiences (PEs) in this structure.MethodsWe evaluated the structure of mental disorders with data from the World Health Organization Composite International Diagnostic Interview, including 15 lifetime mental disorders and six PEs. Respondents (n = 5478-15 499) were included from 10 high-, middle- and lower middle-income countries across the world aged 18 years or older. Confirmatory factor analyses (CFAs) were used to evaluate and compare the fit of different factor structures to the lifetime disorder data. Measurement invariance was evaluated with multigroup CFA (MG-CFA).ResultsA second-order model with internalizing and externalizing factors and fear and distress subfactors best described the structure of common mental disorders. MG-CFA showed that this model was stable across countries. Of the uncommon disorders, bipolar disorder and eating disorder were best grouped with the internalizing factor, and PEs with a separate factor.ConclusionsThese results indicate that cross-national patterns of lifetime common mental-disorder comorbidity can be explained with a second-order underlying structure that is stable across countries and can be extended to also cover less common mental disorders.
  • article 89 Citação(ões) na Scopus
    Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey
    (2016) MCGRATH, John J.; SAHA, Sukanta; AL-HAMZAWI, Ali O.; ALONSO, Jordi; ANDRADE, Laura; BORGES, Guilherme; BROMET, Evelyn J.; BROWNE, Mark Oakley; BRUFFAERTS, Ronny; ALMEIDA, Jose M. Caldas de; FAYYAD, John; FLORESCU, Silvia; GIROLAMO, Giovanni de; GUREJE, Oye; HU, Chiyi; JONGE, Peter de; KOVESS-MASFETY, Viviane; LEPINE, Jean Pierre; LIM, Carmen C. W.; NAVARRO-MATEU, Fernando; PIAZZA, Maria; SAMPSON, Nancy; POSADA-VILLA, Jose; KENDLER, Kenneth S.; KESSLER, Ronald C.
    Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P <.001) but negatively associated with annualized PE frequency rates (F = 8.0, P <.001). Discussion: While most people with lifetime PEs have first onsets in adolescence or young adulthood, projected estimates indicate that nearly a quarter of first onsets occur after age 40 years. The extent to which late onset PEs are associated with (a) late onset mental disorders or (b) declining cognitive and/or sensory function need further research.
  • article 140 Citação(ões) na Scopus
    The cross-national epidemiology of specific phobia in the World Mental Health Surveys
    (2017) WARDENAAR, K. J.; LIM, C. C. W.; AL-HAMZAWI, A. O.; ALONSO, J.; ANDRADE, L. H.; BENJET, C.; BUNTING, B.; GIROLAMO, G. de; DEMYTTENAERE, K.; FLORESCU, S. E.; GUREJE, O.; HISATERU, T.; HU, C.; HUANG, Y.; KARAM, E.; KIEJNA, A.; LEPINE, J. P.; NAVARRO-MATEU, F.; BROWNE, M. Oakley; PIAZZA, M.; POSADA-VILLA, J.; HAVE, M. L. ten; TORRES, Y.; XAVIER, M.; ZARKOV, Z.; KESSLER, R. C.; SCOTT, K. M.; JONGE, P. de
    Background. Although specific phobia is highly prevalent, associated with impairment, and an important risk factor for the development of other mental disorders, cross-national epidemiological data are scarce, especially from low- and middle-income countries. This paper presents epidemiological data from 22 low-, lower-middle-, upper-middle- and high-income countries. Method. Data came from 25 representative population-based surveys conducted in 22 countries (2001-2011) as part of the World Health Organization World Mental Health Surveys initiative (n = 124 902). The presence of specific phobia as defined by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition was evaluated using the World Health Organization Composite International Diagnostic Interview. Results. The cross-national lifetime and 12-month prevalence rates of specific phobia were, respectively, 7.4% and 5.5%, being higher in females (9.8 and 7.7%) than in males (4.9% and 3.3%) and higher in high- and higher-middle-income countries than in low-/lower-middle-income countries. The median age of onset was young (8 years). Of the 12-month patients, 18.7% reported severe role impairment (13.3-21.9% across income groups) and 23.1% reported any treatment (9.6-30.1% across income groups). Lifetime co-morbidity was observed in 60.5% of those with lifetime specific phobia, with the onset of specific phobia preceding the other disorder in most cases (72.6%). Interestingly, rates of impairment, treatment use and co-morbidity increased with the number of fear subtypes. Conclusions. Specific phobia is common and associated with impairment in a considerable percentage of cases. Importantly, specific phobia often precedes the onset of other mental disorders, making it a possible early-life indicator of psychopathology vulnerability.
  • article 0 Citação(ões) na Scopus
    Correlates and prevalence of post-traumatic stress disorders in the Sa tilde o Paulo metropolitan area, Brazil
    (2022) COELHO, Bruno Mendonca; SANTANA, Geilson Lima; DANTAS, Heloisa de Souza; VIANA, Maria Carmen; ANDRADE, Laura Helena; WANG, Yuan-Pang
    Background: Post-traumatic stress disorder (PTSD) is a debilitating condition, which generates an extensive burden. We aimed to investigate in a huge metropolitan area, the prevalence of traumatic experiences, the development of PTSD, and its predictors. Methods: Traumatic experiences and PTSD were assessed in 5037 adult individuals of the general population. Cross-tabulations method assessed the prevalence of traumatic events and PTSD. Logistic regression models investigated predictors of lifetime and 12-month odds of PTSD and the conditional probability of developing PTSD for specific traumas. Results: Lifetime and 12-month diagnoses of PTSD were found in 3.2% and 1.6% of the sample. 'Witnessing anyone being injured or killed, or unexpectedly seeing a dead body' (35,7%) and 'being mugged or threatened with a weapon' (34.0%) were the two most reported traumas. The commonest events before PTSD onset were 'sudden unexpected death of a loved one' (34.0%), 'interpersonal violence' (31.0%), and 'threats to the physical integrity of others' (25.0%). Experiences related to ""interpersonal violence "" presented the highest conditional probability for PTSD (range 2.2-21.2%). Being 'sexually assaulted or molested' (21.2% total; 22.3% women; 0.0% men) and being 'raped' (18.8% total; 18.4% women; 20.1% men) were the two experiences with the highest odds for PTSD. While being female was a predictor of less exposure to any event (OR = 0.69), females were more prone to develop lifetime PTSD after exposure to an event (OR = 2.38). Conclusion: Traumatic events are frequent in the general population and a small group of traumatic events accounts for most cases of subsequent PTSD.
  • article
    How global epidemiological evidence can inform the revision of ICD-10 classification of depression and anxiety disorders
    (2012) ANDRADE, Laura H.; YUAN-PANG, Wang
    This article reviews current evidence from epidemiological surveys that may be relevant for improving the ICD classification of depression and anxiety disorders. Topics of special interest are the boundaries of these disorders, subthreshold presentations, patterns of comorbidity, and cultural variations in somatic presentations. Proposals for hierarchical structures that model the core factors underlying these disorders are presented. The need for a better description of mixed anxiety and depressive disorder in ICD-11 is highlighted. Questions regarding how to model somatic symptoms related to depression and anxiety disorders and how to take the cultural components of the these disorders into account are raised. The challenge of reformulating the current classification in order to enhance clinical utility should not cast aside basic conceptualizations of psychopathology.
  • article 832 Citação(ões) na Scopus
    Mental disorders among college students in the World Health Organization World Mental Health Surveys
    (2016) AUERBACH, R. P.; ALONSO, J.; AXINN, W. G.; CUIJPERS, P.; EBERT, D. D.; GREEN, J. G.; HWANG, I.; KESSLER, R. C.; LIU, H.; MORTIER, P.; NOCK, M. K.; PINDER-AMAKER, S.; SAMPSON, N. A.; AGUILAR-GAXIOLA, S.; AL-HAMZAWI, A.; ANDRADE, L. H.; BENJET, C.; CALDAS-DE-ALMEIDA, J. M.; DEMYTTENAERE, K.; FLORESCU, S.; GIROLAMO, G. de; GUREJE, O.; HARO, J. M.; KARAM, E. G.; KIEJNA, A.; KOVESS-MASFETY, V.; LEE, S.; MCGRATH, J. J.; O'NEILL, S.; PENNELL, B. -E.; SCOTT, K.; HAVE, M. ten; TORRES, Y.; ZASLAVSKY, A. M.; ZARKOV, Z.; BRUFFAERTS, R.
    Background Although mental disorders are significant predictors of educational attainment throughout the entire educational career, most research on mental disorders among students has focused on the primary and secondary school years. Method The World Health Organization World Mental Health Surveys were used to examine the associations of mental disorders with college entry and attrition by comparing college students (n = 1572) and non-students in the same age range (18-22 years; n = 4178), including non-students who recently left college without graduating (n = 702) based on surveys in 21 countries (four low/lower-middle income, five upper-middle-income, one lower-middle or upper-middle at the times of two different surveys, and 11 high income). Lifetime and 12-month prevalence and age-of-onset of DSM-IV anxiety, mood, behavioral and substance disorders were assessed with the Composite International Diagnostic Interview (CIDI). Results One-fifth (20.3%) of college students had 12-month DSM-IV/CIDI disorders; 83.1% of these cases had pre-matriculation onsets. Disorders with pre-matriculation onsets were more important than those with post-matriculation onsets in predicting subsequent college attrition, with substance disorders and, among women, major depression the most important such disorders. Only 16.4% of students with 12-month disorders received any 12-month healthcare treatment for their mental disorders. Conclusions Mental disorders are common among college students, have onsets that mostly occur prior to college entry, in the case of pre-matriculation disorders are associated with college attrition, and are typically untreated. Detection and effective treatment of these disorders early in the college career might reduce attrition and improve educational and psychosocial functioning.
  • article 14 Citação(ões) na Scopus
    Mental disorders among college students in the World Health Organization World Mental Health Surveys (vol 46, pg 2955, 2016)
    (2017) AUERBACH, R. P.; ALONSO, J.; AXINN, W. G.; CUIJPERS, P.; EBERT, D. D.; GREEN, J. G.; HWANG, I.; KESSLER, R. C.; LIU, H.; MORTIER, P.; NOCK, M. K.; PINDER-AMAKER, S.; SAMPSON, N. A.; AGUILAR-GAXIOLA, S.; AL-HAMZAWI, A.; ANDRADE, L. H.; BENJET, C.; CALDAS-DE-ALMEIDA, J. M.; DEMYTTENAERE, K.; FLORESCU, S.; GIROLAMO, G. de; GUREJE, O.; HARO, J. M.; KARAM, E. G.; KIEJNA, A.; KOVESS-MASFETY, V.; LEE, S.; MCGRATH, J. J.; O'NEILL, S.; PENNELL, B. -E.; SCOTT, K.; HAVE, M. ten; TORRES, Y.; ZASLAVSKY, A. M.; ZARKOV, Z.; BRUFFAERTS, R.