ODILSON MARCOS SILVESTRE
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article 26 Citação(ões) na Scopus Impact of the severity of end-stage liver disease in cardiac structure and function(2013) SILVESTRE, Odilson Marcos; BACAL, Fernando; RAMOS, Danusa de Souza; ANDRADE, Jose L.; FURTADO, Meive; PUGLIESE, Vincenzo; BELLETI, Elisangela; ANDRAUS, Wellington; CARRILHO, Flair Jose; D'ALBUQUERQUE, Luiz Augusto Carneiro; FARIAS, Alberto QueirozBackground. The impact of end-stage liver disease (ESLD) in cardiac remodeling of patients with cirrhosis is unknown. Our aim was to correlate the severity of ESLD with morphologic and functional heart changes. Material and methods. 184 patients underwent a protocol providing data on the severity of ESLD and undergoing echocardiography to assess the diameters of the left atrium and right ventricle; the systolic and diastolic diameters of the left ventricle, interventricular septum, and posterior wall of the left ventricle; systolic pulmonary artery pressure; ejection fraction; and diastolic function. Severity of ESLD was assessed by the Model for End-Stage Liver Disease (MELD) score. Results. Left-atrial diameter (r = 0.323; IC 95% 0.190-0.455; p < 0.001), left-ventricular diastolic diameter (r = 0.177; IC 95% 0.033-0.320; p = 0.01) and systolic pulmonary artery pressure (r = 0.185; IC 95% 0.036-0.335; p = 0.02) significantly correlated with MELD score. Patients with MELD 16 had significantly higher left-atrial diameter and systolic pulmonary artery pressure, compared with patients with MELD scores < 16 points. Conclusions. Changes in cardiac structure and function correlate with the severity of ESLD.- Early-Onset and Late-Onset Heart Failure After Liver Transplantation(2014) SILVESTRE, Odilson M.; FARIAS, Alberto Q.; BACAL, Fernando
- Cardiac Dysfunction Related to Cirrhosis(2013) SILVESTRE, Odilson Marcos; FARIAS, Alberto Queiroz; BACAL, Fernando
- Angiogenesis between coronary grafts through the aortic wall(2012) YBARRA, Luiz Fernando; RIBEIRO, Henrique Barbosa; SILVESTRE, Odilson Marcos; CAMPOS, Carlos Augusto Homem de Magalhaes; LOPES JR., Augusto Celso de Araujo; ESPER, Rodrigo Barbosa; BACAL, Fernando; RIBEIRO, Expedito E.
- Serum B-type natriuretic peptide in the initial workup of patients with new onset ascites: A diagnostic accuracy study (vol 59, pg 1043. 2014)(2014) FARIAS, Alberto Q.; SILVESTRE, Odilson M.; GARCIA-TSAO, Guadalupe; SEGURO, Luis F. B. da Costa; MAZO, Daniel F. de Campos; BACAL, Fernando; ANDRADE, Jose L.; GONCALVES, Luciana L.; STRUNZ, Celia; RAMOS, Danusa S.; POLLI, Demerson; PUGLIESE, Vincenzo; RODRIGUES, Ana C. T.; FURTADO, Meive S.; CARRILHO, Flair J.; D'ALBUQUERQUE, Luiz A. C.
- Comparação entre BNP e NT-proBNP quanto à concordância e quanto à influência das variáveis clínicas e laboratoriais(2013) CURIATI, Milena Novaes Cardoso; SILVESTRE, Odilson Marcos; PIRES, Lucas José Tachotti; MANGINI, Sandrigo; PIRES, Philippe Vieira; GAIOTTO, Fabio Antonio; LAURINO, André Micheletto; PêGO-FERNANDES, Paulo Manuel; FERREIRA, Carlos Eduardo dos Santos; BACAL, FernandoOBJECTIVE: To correlate the serum levels of B type natriuretic peptide and the N-terminal fraction of the pro-B type natriuretic peptide, as well as to analyze the influence of age, obesity, renal failure, left ventricle ejection fraction, diastolic dysfunction, and anemia on serum levels of both markers. METHODS: An observational study in which the agreement was compared between these markers in consecutive samples of 138 patients. For the correlation, Pearson's test was used, and p<0.05 was considered statistically significant. RESULTS: A linear association was observed between the B type natriuretic peptide and N-terminal fraction of the pro-B type natriuretic peptide (r=0.907; p<0.001). When evaluating the categorized measurements as normal and altered, there was good agreement, with 90.6% of agreement classifications (p<0.001) in which altered values of the N-terminal fraction of the pro-B type natriuretic peptide and normal values of the B type natriuretic peptide represented 8.7% of the total; the opposite situation represented 1% of the total. Assessment of the influence of the clinical and laboratorial factors on the levels of natriuretic peptides showed that they rise according to age, but that they fall as the ejection fraction increases. Patients with anemia (p<0.001) or with renal failure (p=0.007) had higher values of both markers. There was no association between obesity and the B type natriuretic peptide. CONCLUSION: There was satisfactory agreement between the B type natriuretic peptide and the N-terminal fraction of the pro-B type natriuretic peptide. Age, creatinine levels, and hemoglobin, as well as ventricular function, influence the serum levels of both natriuretic peptides.
- Transcatheter Aortic Valve Implantation as Rescue Therapy for Liver Transplant Candidates With Aortic Valve Stenosis(2014) SILVESTRE, Odilson Marcos; BACAL, Fernando; RAMOS, Danusa Souza; TARASOUTCHI, Flavio; ACORSI, Tarso D.; FERNANDES, Fabio; LEMOS, Pedro A.; CARRILHO, Flair Jose; D'ALBUQUERQUE, Luiz A. C.; FARIAS, Alberto Queiroz
- Heart transplantation: review(2015) MANGINI, Sandrigo; ALVES, Bárbara Rubim; SILVESTRE, Odílson Marcos; PIRES, Philippe Vieira; PIRES, Lucas José Tachotti; CURIATI, Milena Novaes Cardoso; BACAL, FernandoABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants.
- Cardiohepatic Interactions - from Humoral Theory to Organ Transplantation(2014) SILVESTRE, Odilson Marcos; BACAL, Fernando; XIMENES, Rafael Oliveira; CARRILHO, Flair Jose; D'ALBUQUERQUE, Luiz Augusto Carneiro; FARIAS, Alberto Queiroz
conferenceObject Serum B-type natriuretic peptide is more accurate than ascites analyses in the diagnosis of heart failure-related ascites(2012) FARIAS, Alberto Q.; SILVESTRE, Odilson M.; GARCIA-TSAO, Guadalupe; SEGURO, Luis; MAZO, Daniel F.; BACAL, Fernando; ANDRADE, Jose L.; GONCALVES, Luciana L.; CARRILHO, Flair J.; D'ALBU-QUERQUE, Luiz C.