International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCHUNG, Kian Fan
dc.contributor.authorWENZEL, Sally E.
dc.contributor.authorBROZEK, Jan L.
dc.contributor.authorBUSH, Andrew
dc.contributor.authorCASTRO, Mario
dc.contributor.authorSTERK, Peter J.
dc.contributor.authorADCOCK, Ian M.
dc.contributor.authorBATEMAN, Eric D.
dc.contributor.authorBEL, Elisabeth H.
dc.contributor.authorBLEECKER, Eugene R.
dc.contributor.authorBOULET, Louis-Philippe
dc.contributor.authorBRIGHTLING, Christopher
dc.contributor.authorCHANEZ, Pascal
dc.contributor.authorDAHLEN, Sven-Erik
dc.contributor.authorDJUKANOVIC, Ratko
dc.contributor.authorFREY, Urs
dc.contributor.authorGAGA, Mina
dc.contributor.authorGIBSON, Peter
dc.contributor.authorHAMID, Qutayba
dc.contributor.authorJAJOUR, Nizar N.
dc.contributor.authorMAUAD, Thais
dc.contributor.authorSORKNESS, Ronald L.
dc.contributor.authorTEAGUE, W. Gerald
dc.date.accessioned2015-07-01T20:34:05Z
dc.date.available2015-07-01T20:34:05Z
dc.date.issued2014
dc.description.abstractSevere or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American Thoracic Society, reviewed the definition and provided recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults. A literature review was performed, followed by discussion by an expert committee according to the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach for development of specific clinical recommendations. When the diagnosis of asthma is confirmed and comorbidities addressed, severe asthma is defined as asthma that requires treatment with high dose inhaled corticosteroids plus a second controller and/or systemic corticosteroids to prevent it from becoming ""uncontrolled"" or that remains ""uncontrolled"" despite this therapy. Severe asthma is a heterogeneous condition consisting of phenotypes such as eosinophilic asthma. Specific recommendations on the use of sputum eosinophil count and exhaled nitric oxide to guide therapy, as well as treatment with anti-IgE antibody, methotrexate, macrolide antibiotics, antifungal agents and bronchial thermoplasty are provided. Coordinated research efforts for improved phenotyping will provide safe and effective biomarker-driven approaches to severe asthma therapy.
dc.description.indexMEDLINE
dc.description.sponsorshipMedical Research Council
dc.identifier.citationEUROPEAN RESPIRATORY JOURNAL, v.43, n.2, p.343-373, 2014
dc.identifier.doi10.1183/09031936.00202013
dc.identifier.eissn1399-3003
dc.identifier.issn0903-1936
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/9490
dc.language.isoeng
dc.publisherEUROPEAN RESPIRATORY SOC JOURNALS LTD
dc.relation.ispartofEuropean Respiratory Journal
dc.rightsrestrictedAccess
dc.rights.holderCopyright EUROPEAN RESPIRATORY SOC JOURNALS LTD
dc.subject.otherexhaled nitric-oxide
dc.subject.otherair-flow obstruction
dc.subject.otherrandomized controlled-trial
dc.subject.otherplacebo-controlled trial
dc.subject.othersevere persistent asthma
dc.subject.otherpoorly controlled asthma
dc.subject.othergenome-wide association
dc.subject.otherrelative corticosteroid insensitivity
dc.subject.othersputum eosinophil counts
dc.subject.otherallergic airways disease
dc.subject.wosRespiratory System
dc.titleInternational ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryAustrália
hcfmusp.affiliation.countryInglaterra
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryCanadá
hcfmusp.affiliation.countryHolanda
hcfmusp.affiliation.countryÁfrica do Sul
hcfmusp.affiliation.countryFrança
hcfmusp.affiliation.countrySuécia
hcfmusp.affiliation.countrySuíça
hcfmusp.affiliation.countryGrécia
hcfmusp.affiliation.countryisogb
hcfmusp.affiliation.countryisous
hcfmusp.affiliation.countryisoca
hcfmusp.affiliation.countryisonl
hcfmusp.affiliation.countryisoza
hcfmusp.affiliation.countryisofr
hcfmusp.affiliation.countryisose
hcfmusp.affiliation.countryisoch
hcfmusp.affiliation.countryisogr
hcfmusp.affiliation.countryisoau
hcfmusp.author.externalCHUNG, Kian Fan:Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London SW3 6LY, England; Royal Brompton Hosp, Biomed Res Unit, London SW3 6LY, England
hcfmusp.author.externalWENZEL, Sally E.:Univ Pittsburgh, Dept Med, Pittsburgh, PA USA
hcfmusp.author.externalBROZEK, Jan L.:McMaster Univ, Dept Clin Epidemiol & Biostat & Med, Hamilton, ON, Canada
hcfmusp.author.externalBUSH, Andrew:Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London SW3 6LY, England; Royal Brompton Hosp, Biomed Res Unit, London SW3 6LY, England
hcfmusp.author.externalCASTRO, Mario:Washington Univ, Dept Med, St Louis, MO USA
hcfmusp.author.externalSTERK, Peter J.:Univ Amsterdam, Acad Med Ctr, Dept Resp Med, NL-1105 AZ Amsterdam, Netherlands
hcfmusp.author.externalADCOCK, Ian M.:Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London SW3 6LY, England
hcfmusp.author.externalBATEMAN, Eric D.:Univ Cape Town, Lung Inst, ZA-7925 Cape Town, South Africa
hcfmusp.author.externalBEL, Elisabeth H.:Univ Amsterdam, Acad Med Ctr, Dept Resp Med, NL-1105 AZ Amsterdam, Netherlands
hcfmusp.author.externalBLEECKER, Eugene R.:Wake Forest Univ, Dept Med, Winston Salem, NC 27109 USA
hcfmusp.author.externalBOULET, Louis-Philippe:Inst Univ Cardiol & Pneumol Quebec, Ctr Rech, Quebec City, PQ, Canada
hcfmusp.author.externalBRIGHTLING, Christopher:Univ Leicester, Inst Lung Hlth, Leicester, Leics, England
hcfmusp.author.externalCHANEZ, Pascal:Marseille Univ, Dept Malad Resp, Marseille, France
hcfmusp.author.externalDAHLEN, Sven-Erik:Karolinska Inst, Inst Environm Med, S-10401 Stockholm, Sweden
hcfmusp.author.externalDJUKANOVIC, Ratko:Univ Southampton, Sch Med, Southampton NIHR Resp Biomed Res Unit, Southampton, Hants, England; Southampton Gen Hosp, Southampton SO9 4XY, Hants, England
hcfmusp.author.externalFREY, Urs:Univ Basel, Univ Childrens Hosp UKBB, Basel, Switzerland
hcfmusp.author.externalGAGA, Mina:Athens Chest Hosp, Resp Dept 7, Athens, Greece; Athens Chest Hosp, Asthma Ctr, Athens, Greece
hcfmusp.author.externalGIBSON, Peter:John Hunter Hosp, Hunter Med Res Inst, Newcastle, NSW, Australia
hcfmusp.author.externalHAMID, Qutayba:McGill Univ, Meakins Christie Labs, Montreal, PQ, Canada
hcfmusp.author.externalJAJOUR, Nizar N.:Univ Wisconsin, Dept Med, Madison, WI USA
hcfmusp.author.externalSORKNESS, Ronald L.:Univ Wisconsin, Dept Med, Madison, WI USA
hcfmusp.author.externalTEAGUE, W. Gerald:Univ Virginia, Sch Med, Dept Paediat, Div Resp Med Allergy & Immunol, Charlottesville, VA 22903 USA
hcfmusp.citation.scopus2849
hcfmusp.contributor.author-fmusphcTHAIS MAUAD
hcfmusp.description.beginpage343
hcfmusp.description.endpage373
hcfmusp.description.issue2
hcfmusp.description.volume43
hcfmusp.origemWOS
hcfmusp.origem.pubmed24337046
hcfmusp.origem.scopus2-s2.0-84893513577
hcfmusp.origem.wosWOS:000330824500010
hcfmusp.publisher.citySHEFFIELD
hcfmusp.publisher.countryENGLAND
hcfmusp.relation.referenceAaron SD, 2008, CAN MED ASSOC J, V179, P1121, DOI 10.1503/cmaj.081332
hcfmusp.relation.referenceAdams NP, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003534.pub3
hcfmusp.relation.referenceAldridge RE, 2000, AM J RESP CRIT CARE, V161, P1459
hcfmusp.relation.referenceAllen David B, 2007, Expert Rev Respir Med, V1, P65, DOI 10.1586/17476348.1.1.65
hcfmusp.relation.referenceALLEN DB, 1994, J ALLERGY CLIN IMMUN, V93, P967, DOI 10.1016/S0091-6749(94)70043-5
hcfmusp.relation.referenceAllen David B, 2003, J Allergy Clin Immunol, V112, pS1, DOI 10.1016/S0091-6749(03)01859-1
hcfmusp.relation.referenceAl-Ramli W, 2009, J ALLERGY CLIN IMMUN, V123, P1185, DOI 10.1016/j.jaci.2009.02.024
hcfmusp.relation.referenceAl-Samri MT, 2010, J ALLERGY CLIN IMMUN, V125, P1161, DOI 10.1016/j.jaci.2010.02.005
hcfmusp.relation.reference[Anonymous], 2000, AM J RESP CRIT CARE, V162, P2341
hcfmusp.relation.reference[Anonymous], 1987, AM REV RESP DIS, V136, P225
hcfmusp.relation.referenceAuffray C, 2010, CHEST, V137, P1410, DOI 10.1378/chest.09-1850
hcfmusp.relation.referenceAYRES J, 1984, BRIT MED J, V288, P1715
hcfmusp.relation.referenceAysola RS, 2008, CHEST, V134, P1183, DOI 10.1378/chest.07-2779
hcfmusp.relation.referenceBaines KJ, 2011, J ALLERGY CLIN IMMUN, V127, P153, DOI 10.1016/j.jaci.2010.10.024
hcfmusp.relation.referenceBalzar S, 2011, AM J RESP CRIT CARE, V183, P299, DOI 10.1164/rccm.201002-0295OC
hcfmusp.relation.referenceBateman ED, 2004, AM J RESP CRIT CARE, V170, P836, DOI 10.1164/rccm.200401-033OC
hcfmusp.relation.referenceBeisswenger C, 2006, J IMMUNOL, V177, P1833
hcfmusp.relation.referenceBel EH, 2011, THORAX, V66, P910, DOI 10.1136/thx.2010.153643
hcfmusp.relation.referenceBerry M, 2007, THORAX, V62, P1043, DOI 10.1136/thx.2006.073429
hcfmusp.relation.referenceBerry MA, 2006, NEW ENGL J MED, V354, P697, DOI 10.1056/NEJMoa050580
hcfmusp.relation.referenceBhavsar P, 2008, THORAX, V63, P784, DOI 10.1136/thx.2007.090027
hcfmusp.relation.referenceBhavsar PK, 2010, RESP RES, V11, DOI 10.1186/1465-9921-11-71
hcfmusp.relation.referenceBossley CJ, 2012, J ALLERGY CLIN IMMUN, V129, P974, DOI 10.1016/j.jaci.2012.01.059
hcfmusp.relation.referenceBossley CJ, 2009, EUR RESPIR J, V34, P1052, DOI 10.1183/09031936.00186508
hcfmusp.relation.referenceBourdin A, 2007, J ALLERGY CLIN IMMUN, V119, P1367, DOI 10.1016/j.jaci.2007.01.055
hcfmusp.relation.referenceBousquet J, 2010, J ALLERGY CLIN IMMUN, V126, P926, DOI 10.1016/j.jaci.2010.07.019
hcfmusp.relation.referenceBracken M, 2009, ARCH DIS CHILD, V94, P780, DOI 10.1136/adc.2008.152140
hcfmusp.relation.referenceBrasier AR, 2010, CTS-CLIN TRANSL SCI, V3, P147, DOI 10.1111/j.1752-8062.2010.00204.x
hcfmusp.relation.referenceBrightling CE, 2002, NEW ENGL J MED, V346, P1699, DOI 10.1056/NEJMoa012705
hcfmusp.relation.referenceBrutsche MH, 2000, LANCET, V356, P556, DOI 10.1016/S0140-6736(00)02581-2
hcfmusp.relation.referenceBumbacea D, 2004, EUR RESPIR J, V24, P122, DOI 10.1183/09031936.04.00077803
hcfmusp.relation.referenceBusacker A, 2009, CHEST, V135, P48, DOI 10.1378/chest.08-0049
hcfmusp.relation.referenceBush A, 2010, LANCET, V376, P814, DOI 10.1016/S0140-6736(10)61054-9
hcfmusp.relation.referenceBusse WW, 2008, AM J RESP CRIT CARE, V178, P1002, DOI 10.1164/rccm.200708-1200OC
hcfmusp.relation.referenceCastro M, 2011, AM J RESP CRIT CARE, V184, P1125, DOI 10.1164/rccm.201103-0396OC
hcfmusp.relation.referenceCates CJ, 2006, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD000052.pub2
hcfmusp.relation.referenceChakir J, 2002, CLIN EXP ALLERGY, V32, P578, DOI 10.1046/j.0954-7894.2002.01323.x
hcfmusp.relation.referenceChalmers GW, 2002, THORAX, V57, P226, DOI 10.1136/thorax.57.3.226
hcfmusp.relation.referenceChang PJ, 2012, J ALLERGY CLIN IMMUN, V130, P877, DOI 10.1016/j.jaci.2012.07.017
hcfmusp.relation.referenceChaudhuri R, 2006, AM J RESP CRIT CARE, V174, P127, DOI 10.1164/rccm.200510-1589OC
hcfmusp.relation.referenceChu HW, 2007, J IMMUNOL, V179, P3995
hcfmusp.relation.referenceChung KF, 1999, EUR RESPIR J, V13, P1198
hcfmusp.relation.referenceCohen L, 2007, AM J RESP CRIT CARE, V176, P138, DOI 10.1164/rccm.200607-1062OC
hcfmusp.relation.referenceCollison A, 2011, J ALLERGY CLIN IMMUN, V128, P160, DOI 10.1016/j.jaci.2011.04.005
hcfmusp.relation.referenceComhair SAA, 2011, PLOS ONE, V6, DOI 10.1371/journal.pone.0018574
hcfmusp.relation.referenceComhair SAA, 2005, AM J RESP CRIT CARE, V172, P306, DOI 10.1164/rccm.200502-180OC
hcfmusp.relation.referenceCorren J, 2010, AM J RESP CRIT CARE, V181, P788, DOI 10.1164/rccm.200909-1448OC
hcfmusp.relation.referenceCorren J, 2011, NEW ENGL J MED, V365, P1088, DOI 10.1056/NEJMoa1106469
hcfmusp.relation.referenceDahlen B, 1998, AM J RESP CRIT CARE, V157, P1187
hcfmusp.relation.referenceDahlen SE, 2002, AM J RESP CRIT CARE, V165, P9
hcfmusp.relation.referenceDavies H, 2000, COCHRANE DB SYST REV
hcfmusp.relation.referencede Lange EE, 2006, CHEST, V130, P1055, DOI 10.1378/chest.130.4.1055
hcfmusp.relation.referenceDixon AE, 2011, J ALLERGY CLIN IMMUN, V128, P508, DOI 10.1016/j.jaci.2011.06.009
hcfmusp.relation.referenceDoe C, 2010, CHEST, V138, P1140, DOI 10.1378/chest.09-3058
hcfmusp.relation.referenceDolhnikoff M, 2009, J ALLERGY CLIN IMMUN, V123, P1090, DOI 10.1016/j.jaci.2009.02.032
hcfmusp.relation.referenceDougherty RH, 2010, J ALLERGY CLIN IMMUN, V125, P1046, DOI 10.1016/j.jaci.2010.03.003
hcfmusp.relation.referenceDucharme FM, 2006, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003137.pub3
hcfmusp.relation.referenceDweik RA, 2011, AM J RESP CRIT CARE, V184, P602, DOI [10.1164/rccm.9120-11ST, 10.1164/rccm.912011ST]
hcfmusp.relation.referenceDweik RA, 2010, AM J RESP CRIT CARE, V181, P1033, DOI 10.1164/rccm.200905-0695OC
hcfmusp.relation.referenceEvans DJ, 1997, NEW ENGL J MED, V337, P1412, DOI 10.1056/NEJM199711133372002
hcfmusp.relation.referenceFens N, 2011, CLIN EXP ALLERGY, V41, P1371, DOI 10.1111/j.1365-2222.2011.03800.x
hcfmusp.relation.referenceFens N, 2011, EUR RESPIR J, V38, P1301, DOI 10.1183/09031936.00032911
hcfmusp.relation.referenceFitzpatrick AM, 2010, J ALLERGY CLIN IMMUN, V125, P851, DOI 10.1016/j.jaci.2010.01.048
hcfmusp.relation.referenceFitzpatrick AM, 2008, J ALLERGY CLIN IMMUN, V121, P1372, DOI 10.1016/j.jaci.2008.03.008
hcfmusp.relation.referenceFitzpatrick AM, 2006, J ALLERGY CLIN IMMUN, V118, P1218, DOI 10.1016/j.jaci.2006.08.019
hcfmusp.relation.referenceFitzpatrick AM, 2011, J ALLERGY CLIN IMMUN, V127, P382, DOI 10.1016/j.jaci.2010.11.015
hcfmusp.relation.referenceFleming L, 2012, THORAX, V67, P675, DOI 10.1136/thoraxjnl-2011-201064
hcfmusp.relation.referenceFleming L, 2012, THORAX, V67, P193, DOI 10.1136/thx.2010.156836
hcfmusp.relation.referenceFlood-Page P, 2007, AM J RESP CRIT CARE, V176, P1062, DOI 10.1164/rccm.200701-085OC
hcfmusp.relation.referenceForno E, 2012, J ALLERGY CLIN IMMUN, V130, P83, DOI 10.1016/j.jaci.2012.03.020
hcfmusp.relation.referenceFrey U, 2008, LANCET, V372, P1088, DOI 10.1016/S0140-6736(08)61450-6
hcfmusp.relation.referenceFrey U, 2005, NATURE, V438, P667, DOI 10.1038/nature04176
hcfmusp.relation.referenceFriedman MS, 2001, JAMA-J AM MED ASSOC, V285, P897, DOI 10.1001/jama.285.7.897
hcfmusp.relation.referenceGamble J, 2011, RESP MED, V105, P1308, DOI 10.1016/j.rmed.2011.03.019
hcfmusp.relation.referenceGelb AF, 2004, CHEST, V126, P1138, DOI 10.1378/chest.126.4.1138
hcfmusp.relation.referenceGoleva E, 2008, J ALLERGY CLIN IMMUN, V122, P550, DOI 10.1016/j.jaci.2008.07.007
hcfmusp.relation.referenceGood JT, 2012, CHEST, V141, P599, DOI 10.1378/chest.11-0741
hcfmusp.relation.referenceGras D, 2012, J ALLERGY CLIN IMMUN, V129, P1259, DOI 10.1016/j.jaci.2012.01.073
hcfmusp.relation.referenceGreen RH, 2002, LANCET, V360, P1715, DOI 10.1016/S0140-6736(02)11679-5
hcfmusp.relation.referenceGreenwald R, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0011919
hcfmusp.relation.referenceGrossman JM, 2010, ARTHRIT CARE RES, V62, P1515, DOI 10.1002/acr.20295
hcfmusp.relation.referenceGupta A, 2011, AM J RESP CRIT CARE, V184, P1342, DOI 10.1164/rccm.201107-1239OC
hcfmusp.relation.referenceGupta S, 2009, CHEST, V136, P1521, DOI 10.1378/chest.09-0174
hcfmusp.relation.referenceGuyatt G, 2011, J CLIN EPIDEMIOL, V64, P383, DOI 10.1016/j.jclinepi.2010.04.026
hcfmusp.relation.referenceHaldar P, 2009, NEW ENGL J MED, V360, P973, DOI 10.1056/NEJMoa0808991
hcfmusp.relation.referenceHaldar P, 2008, AM J RESP CRIT CARE, V178, P218, DOI [10.1164/rccm.200711-1754OC, 10.1164/rccm.200711-17540C]
hcfmusp.relation.referenceHaselkorn T, 2009, J ALLERGY CLIN IMMUN, V124, P921, DOI 10.1016/j.jaci.2009.09.006
hcfmusp.relation.referenceHassan M, 2010, J ALLERGY CLIN IMMUN, V125, P1037, DOI 10.1016/j.jaci.2010.02.031
hcfmusp.relation.referenceHastie AT, 2010, J ALLERGY CLIN IMMUN, V125, P1028, DOI 10.1016/j.jaci.2010.02.008
hcfmusp.relation.referenceHawkins GA, 2012, J ALLERGY CLIN IMMUN, V130, P510, DOI 10.1016/j.jaci.2012.03.018
hcfmusp.relation.referenceHeaney LG, 2003, THORAX, V58, P561, DOI 10.1136/thorax.58.7.561
hcfmusp.relation.referenceHeaney LG, 2005, RESP MED, V99, P1152, DOI 10.1016/j.rmed.2005.02.013
hcfmusp.relation.referenceHenneberger PK, 2010, EUR RESPIR J, V36, P743, DOI 10.1183/09031936.00135109
hcfmusp.relation.referenceHew M, 2010, INTERN MED J, V40, P323, DOI 10.1111/j.1445-5994.2010.02192.x
hcfmusp.relation.referenceHew M, 2006, AM J RESP CRIT CARE, V174, P134, DOI 10.1164/rccm.200512-1930OC
hcfmusp.relation.referenceHilty M, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0008578
hcfmusp.relation.referenceHolbrook JT, 2012, JAMA-J AM MED ASSOC, V307, P373, DOI 10.1001/jama.2011.2035
hcfmusp.relation.referenceHolguin F, 2011, J ALLERGY CLIN IMMUN, V127, P1486, DOI 10.1016/j.jaci.2011.03.036
hcfmusp.relation.referenceHORN BR, 1975, NEW ENGL J MED, V292, P1152, DOI 10.1056/NEJM197505292922204
hcfmusp.relation.referenceHumbert M, 2009, ALLERGY, V64, P1194, DOI 10.1111/j.1398-9995.2009.02122.x
hcfmusp.relation.referenceHuynh MLN, 2005, AM J RESP CRIT CARE, V172, P972, DOI 10.1164/rccm.200501-0350C
hcfmusp.relation.referenceIto K, 2006, J ALLERGY CLIN IMMUN, V117, P522, DOI 10.1016/j.jaci.2006.01.032
hcfmusp.relation.referenceJackson DJ, 2008, AM J RESP CRIT CARE, V178, P667, DOI 10.1164/rccm.200802-309OC
hcfmusp.relation.referenceJames AL, 2009, EUR RESPIR J, V34, P1040, DOI 10.1183/09031936.00181608
hcfmusp.relation.referenceJatakanon A, 1999, THORAX, V54, P234
hcfmusp.relation.referenceJatakanon A, 1999, AM J RESP CRIT CARE, V160, P1532
hcfmusp.relation.referenceJia GQ, 2012, J ALLERGY CLIN IMMUN, V130, P647, DOI 10.1016/j.jaci.2012.06.025
hcfmusp.relation.referenceKaminska M, 2009, J ALLERGY CLIN IMMUN, V124, P45, DOI 10.1016/j.jaci.2009.03.049
hcfmusp.relation.referenceKelly HW, 2012, NEW ENGL J MED, V367, P904, DOI 10.1056/NEJMoa1203229
hcfmusp.relation.referenceKerstjens HAM, 2012, NEW ENGL J MED, V367, P1198, DOI 10.1056/NEJMoa1208606
hcfmusp.relation.referenceKerstjens HAM, 2011, J ALLERGY CLIN IMMUN, V128, P308, DOI 10.1016/j.jaci.2011.04.039
hcfmusp.relation.referenceKips JC, 2003, AM J RESP CRIT CARE, V167, P1655, DOI 10.1164/rccm.200206-525OC
hcfmusp.relation.referenceKishiyama JL, 1999, CLIN IMMUNOL, V91, P126, DOI 10.1006/clim.1999.4714
hcfmusp.relation.referenceKnutsen AP, 2012, J ALLERGY CLIN IMMUN, V129, P280, DOI 10.1016/j.jaci.2011.12.970
hcfmusp.relation.referenceKomakula S, 2007, RESP RES, V8, DOI 10.1186/1465-9921-8-32
hcfmusp.relation.referenceKowalski ML, 2011, ALLERGY, V66, P32, DOI 10.1111/j.1398-9995.2010.02379.x
hcfmusp.relation.referenceLAI CKW, 1989, AM REV RESPIR DIS, V140, P917
hcfmusp.relation.referenceLajoie S, 2010, NAT IMMUNOL, V11, P928, DOI 10.1038/ni.1926
hcfmusp.relation.referenceLazarus SC, 2007, AM J RESP CRIT CARE, V175, P783, DOI 10.1164/rccm.200511-17460C
hcfmusp.relation.referenceLazarus SC, 2001, JAMA-J AM MED ASSOC, V285, P2583, DOI 10.1001/jama.285.20.2583
hcfmusp.relation.referenceLee JH, 2007, CHEST, V132, P1882, DOI 10.1378/chest.07-0713
hcfmusp.relation.referenceLemanske RF, 2010, NEW ENGL J MED, V362, P975, DOI 10.1056/NEJMoa1001278
hcfmusp.relation.referenceLemiere C, 2006, J ALLERGY CLIN IMMUN, V118, P1033, DOI 10.1016/j.jaci.2006.08.003
hcfmusp.relation.referenceLevy BD, 2005, AM J RESP CRIT CARE, V172, P824, DOI 10.1164/rccm.200410-1413OC
hcfmusp.relation.referenceLex C, 2006, AM J RESP CRIT CARE, V174, P1286, DOI 10.1164/rccm.200603-352OC
hcfmusp.relation.referenceLi XN, 2010, J ALLERGY CLIN IMMUN, V125, P328, DOI 10.1016/j.jaci.2009.11.018
hcfmusp.relation.referenceLi XN, 2011, J ALLERGY CLIN IMMUN, V127, P1457, DOI 10.1016/j.jaci.2011.01.056
hcfmusp.relation.referenceLock SH, 1996, AM J RESP CRIT CARE, V153, P509
hcfmusp.relation.referenceLotvall J, 2011, J ALLERGY CLIN IMMUN, V127, P355, DOI 10.1016/j.jaci.2010.11.037
hcfmusp.relation.referenceLouis R, 2000, AM J RESP CRIT CARE, V161, P9
hcfmusp.relation.referenceMacedo P, 2009, CLIN EXP ALLERGY, V39, P1668, DOI 10.1111/j.1365-2222.2009.03319.x
hcfmusp.relation.referenceHanania NA, 2009, NEW ENGL J MED, V360, P1487
hcfmusp.relation.referenceMattes J, 2009, P NATL ACAD SCI USA, V106, P18704, DOI 10.1073/pnas.0905063106
hcfmusp.relation.referenceMauad T, 2004, AM J RESP CRIT CARE, V170, P857, DOI 10.1164/rccm.200403-305OC
hcfmusp.relation.referenceMcGrath KW, 2012, AM J RESP CRIT CARE, V185, P612, DOI 10.1164/rccm.201109-1640OC
hcfmusp.relation.referenceMcKinley L, 2008, J IMMUNOL, V181, P4089
hcfmusp.relation.referenceMiranda C, 2004, J ALLERGY CLIN IMMUN, V113, P101, DOI 10.1016/j.jaci.2003.10.041
hcfmusp.relation.referenceMoffatt MF, 2010, NEW ENGL J MED, V363, P1211, DOI 10.1056/NEJMoa0906312
hcfmusp.relation.referenceMoore WC, 2007, J ALLERGY CLIN IMMUN, V119, P405, DOI 10.1016/j.jaci.2006.11.639
hcfmusp.relation.referenceMoore WC, 2010, AM J RESP CRIT CARE, V181, P315, DOI 10.1164/rccm.200906-0896OC
hcfmusp.relation.referenceMorgan WJ, 2004, NEW ENGL J MED, V351, P1068, DOI 10.1056/NEJMoa032097
hcfmusp.relation.referenceNair P, 2009, NEW ENGL J MED, V360, P985, DOI 10.1056/NEJMoa0805435
hcfmusp.relation.referenceNair P, 2012, CLIN EXP ALLERGY, V42, P1097, DOI 10.1111/j.1365-2222.2012.04014.x
hcfmusp.relation.referenceNaqvi M, 2008, ANN ALLERG ASTHMA IM, V100, P551, DOI 10.1016/S1081-1206(10)60055-5
hcfmusp.relation.referenceNational Heart Lung and Blood Institute, 2007, 3 NAT HEART LUNG BLO
hcfmusp.relation.referenceNguyen LT, 2005, RESP MED, V99, P200, DOI 10.1016/j.rmed.2004.06.007
hcfmusp.relation.referenceNi Chroinin M, 2009, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007949
hcfmusp.relation.referenceNIEROP G, 1992, THORAX, V47, P349, DOI 10.1136/thx.47.5.349
hcfmusp.relation.referenceOborne J, 2009, AM J RESP CRIT CARE, V180, P598, DOI 10.1164/rccm.200904-0616OC
hcfmusp.relation.referenceOGIRALA RG, 1991, NEW ENGL J MED, V324, P585, DOI 10.1056/NEJM199102283240903
hcfmusp.relation.referencePakhale S, CHEST, V137, P1316
hcfmusp.relation.referencePasternack R, 2005, J ALLERGY CLIN IMMUN, V116, P1123, DOI 10.1016/j.jaci.2005.08.030
hcfmusp.relation.referencePavord ID, 1999, LANCET, V353, P2213, DOI 10.1016/S0140-6736(99)01813-9
hcfmusp.relation.referencePavord ID, 2012, LANCET, V380, P651, DOI 10.1016/S0140-6736(12)60988-X
hcfmusp.relation.referencePayne DNR, 2003, AM J RESP CRIT CARE, V167, P78, DOI 10.1164/rccm.200205-414OC
hcfmusp.relation.referencePedersen S, 2001, AM J RESP CRIT CARE, V164, P521
hcfmusp.relation.referencePedersen SE, 2007, J ALLERGY CLIN IMMUN, V120, P1036, DOI 10.1016/j.jaci.2007.07.016
hcfmusp.relation.referencePeters SP, 2010, NEW ENGL J MED, V363, P1715, DOI 10.1056/NEJMoa1008770
hcfmusp.relation.referencePeters-Golden M, 2006, EUR RESPIR J, V27, P495, DOI 10.1183/09031936.06.00077205
hcfmusp.relation.referencePiper E, 2013, EUR RESPIR J, V41, P330, DOI 10.1183/09031936.00223411
hcfmusp.relation.referenceReddel HK, 2006, EUR RESPIR J, V28, P182, DOI 10.1183/09031936.06.00105305
hcfmusp.relation.referenceReddel HK, 2009, AM J RESP CRIT CARE, V180, P59, DOI 10.1164/rccm.200801-060ST
hcfmusp.relation.referenceRobinson DS, 2003, EUR RESPIR J, V22, P478, DOI 10.1183/09031936.03.00017003
hcfmusp.relation.referenceRobinson DS, 2001, LANCET, V357, P2007, DOI 10.1016/S0140-6736(00)05113-8
hcfmusp.relation.referenceRodrigo GJ, 2005, THORAX, V60, P740, DOI 10.1136/thx.2005.040444
hcfmusp.relation.referenceSaglani S, 2006, RESP RES, V7, DOI 10.1186/1465-9921-7-46
hcfmusp.relation.referenceSales J, 2008, J PEDIATR PSYCHOL, V33, P208, DOI 10.1093/jpepsy/jsm068
hcfmusp.relation.referenceSalmun LM, 1999, J ALLERGY CLIN IMMUN, V103, P810, DOI 10.1016/S0091-6749(99)70424-0
hcfmusp.relation.referenceSaunders R, 2009, J ALLERGY CLIN IMMUN, V123, P376, DOI 10.1016/j.jaci.2008.10.048
hcfmusp.relation.referenceSEARS MR, 1987, BRIT MED J, V294, P477
hcfmusp.relation.referenceSeddon P, 2006, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD002885.PUB2
hcfmusp.relation.referenceShannon J, 2008, CHEST, V133, P420, DOI 10.1378/chest.07-1881
hcfmusp.relation.referenceShikotra A, 2012, J ALLERGY CLIN IMMUN, V129, P104, DOI 10.1016/j.jaci.2011.08.031
hcfmusp.relation.referenceSimon MR, 2010, J ALLERGY CLIN IMMUN, V126, P527, DOI 10.1016/j.jaci.2010.05.016
hcfmusp.relation.referenceSimpson JL, 2006, RESPIROLOGY, V11, P54, DOI 10.1111/j.1440-1843.2006.00784.x
hcfmusp.relation.referenceSimpson JL, 2005, AM J RESP CRIT CARE, V172, P559, DOI 10.1164/rccm.200503.369OC
hcfmusp.relation.referenceSin DD, 2008, THORAX, V63, P1018, DOI 10.1136/thx.2007.086819
hcfmusp.relation.referenceSlager RE, 2012, J ALLERGY CLIN IMMUN, V130, P516, DOI 10.1016/j.jaci.2012.03.030
hcfmusp.relation.referenceSorkness RL, 2008, J APPL PHYSIOL, V104, P394, DOI 10.1152/japplphysiol.00329.2007
hcfmusp.relation.referenceSpears M, 2009, EUR RESPIR J, V33, P1010, DOI 10.1183/09031936.00158208
hcfmusp.relation.referenceStern DA, 2008, LANCET, V372, P1058, DOI 10.1016/S0140-6736(08)61447-6
hcfmusp.relation.referenceStern G, 2011, J ALLERGY CLIN IMMUN, V128, P293, DOI 10.1016/j.jaci.2011.03.010
hcfmusp.relation.referenceStirling RG, 1998, THORAX, V53, P1030
hcfmusp.relation.referenceSUISSA S, 1994, AM J RESP CRIT CARE, V149, P604
hcfmusp.relation.referenceSutherland ER, 2008, AM J RESP CRIT CARE, V178, P682, DOI 10.1164/rccm.200801-076OC
hcfmusp.relation.referenceTantisira KG, 2011, NEW ENGL J MED, V365, P1173, DOI 10.1056/NEJMoa0911353
hcfmusp.relation.referenceTAYLOR DR, 1993, THORAX, V48, P134, DOI 10.1136/thx.48.2.134
hcfmusp.relation.referenceTaylor DR, 2008, J ALLERGY CLIN IMMUN, V122, P836, DOI 10.1016/j.jaci.2008.07.025
hcfmusp.relation.referenceten Brinke A, 2005, EUR RESPIR J, V26, P812, DOI 10.1183/09031936.05.00037905
hcfmusp.relation.referenceten Brinke A, 2001, J ALLERGY CLIN IMMUN, V107, P449, DOI 10.1067/mai.2001.113047
hcfmusp.relation.referenceten Brinke A, 2002, J ALLERGY CLIN IMMUN, V109, P621, DOI 10.1067/mai.2002.122458
hcfmusp.relation.referenceten Brinke A, 2001, AM J RESP CRIT CARE, V164, P744
hcfmusp.relation.referenceten Brinke A, 2004, AM J RESP CRIT CARE, V170, P601, DOI 10.1164/rccm.200404-440OC
hcfmusp.relation.referenceTeoh L, 2012, COCHRANE DB SYST REV, V4
hcfmusp.relation.referenceThamrin C, 2011, THORAX, V66, P1036, DOI 10.1136/thx.2010.156489
hcfmusp.relation.referenceThamrin C, 2011, J ALLERGY CLIN IMMUN, V127, P1494, DOI 10.1016/j.jaci.2011.01.018
hcfmusp.relation.referenceAbraham B, 2003, EUR RESPIR J, V22, P470, DOI 10.1183/09031936.03.00261903
hcfmusp.relation.referenceTillie-Leblond I, 2008, ALLERGY, V63, P533, DOI 10.1111/j.1398-9995.2008.01656.x
hcfmusp.relation.referenceTorgerson DG, 2011, NAT GENET, V43, P887, DOI 10.1038/ng.888
hcfmusp.relation.referenceTsitsiou E, 2012, J ALLERGY CLIN IMMUN, V129, P95, DOI 10.1016/j.jaci.2011.08.011
hcfmusp.relation.referenceTurchiarelli V, 2011, ALLERGY, V66, P1099, DOI 10.1111/j.1398-9995.2011.02600.x
hcfmusp.relation.reference't Veen JCCMI, 2000, AM J RESP CRIT CARE, V161, P1902
hcfmusp.relation.referenceVachier I, 2005, J ALLERGY CLIN IMMUN, V115, P55, DOI 10.1016/j.jaci.2004.09.038
hcfmusp.relation.referenceVamos M, 1999, AUST NZ J PSYCHIAT, V33, P538, DOI 10.1080/j.1440-1614.1999.00591.x
hcfmusp.relation.referenceVan Staa TP, 2003, J BONE MINER RES, V18, P913, DOI 10.1359/jbmr.2003.18.5.913
hcfmusp.relation.referencevan Veen IH, 2008, EUR RESPIR J, V32, P344, DOI 10.1183/09031936.00135907
hcfmusp.relation.referencevan Veen IH, 2009, J ALLERGY CLIN IMMUN, V124, P615, DOI 10.1016/j.jaci.2009.06.029
hcfmusp.relation.referenceVicencio AG, 2010, PEDIATRICS, V125, pE1255, DOI 10.1542/peds.2009-2443
hcfmusp.relation.referenceVignola AM, 1998, AM J RESP CRIT CARE, V158, P1945
hcfmusp.relation.referenceVirchow JC, 2000, AM J RESP CRIT CARE, V162, P578
hcfmusp.relation.referenceWang CH, 2008, AM J RESP CRIT CARE, V178, P583, DOI 10.1164/rccm.200710-1557OC
hcfmusp.relation.referenceWark PAB, 2005, J EXP MED, V201, P937, DOI 10.1084/jem.20041901
hcfmusp.relation.referenceWechsler ME, 2011, AM J RESP CRIT CARE, V184, P1247, DOI 10.1164/rccm.201103-0514OC
hcfmusp.relation.referenceWenzel SE, 2007, AM J RESP CRIT CARE, V175, P570, DOI 10.1164/rccm.200607-909OC
hcfmusp.relation.referenceWenzel SE, 1999, AM J RESP CRIT CARE, V160, P1001
hcfmusp.relation.referenceWenzel SE, 2009, AM J RESP CRIT CARE, V179, P549, DOI 10.1164/rccm.200809-1512OC
hcfmusp.relation.referenceWoodruff PG, 2009, AM J RESP CRIT CARE, V180, P388, DOI 10.1164/rccm.200903-0392OC
hcfmusp.relation.referenceWos M, 2008, AM J RESP CRIT CARE, V177, P1082, DOI 10.1164/rccm.200607-973OC
hcfmusp.relation.referenceXystrakis E, 2006, J CLIN INVEST, V116, P146, DOI 10.1172/JCI21759
hcfmusp.relation.referenceYamamoto M, 2011, CLIN EXP ALLERGY, V42, P760
hcfmusp.relation.referenceYorke J, 2006, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD002982.pub3
hcfmusp.relation.referenceZhang QL, 2012, RESP RES, V13, DOI 10.1186/1465-9921-13-35
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