Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorFUENTES, Lisa de las
dc.contributor.authorSCHWANDER, Karen L. M.
dc.contributor.authorBROWN, Michael R.
dc.contributor.authorBENTLEY, Amy R.
dc.contributor.authorWINKLER, Thomas W.
dc.contributor.authorSUNG, Yun Ju
dc.contributor.authorMUNROE, Patricia B.
dc.contributor.authorMILLER, Clint L.
dc.contributor.authorASCHARD, Hugo
dc.contributor.authorASLIBEKYAN, Stella
dc.contributor.authorBARTZ, Traci M.
dc.contributor.authorBIELAK, Lawrence F.
dc.contributor.authorCHAI, Jin Fang
dc.contributor.authorCHENG, Ching-Yu
dc.contributor.authorDORAJOO, Rajkumar
dc.contributor.authorFEITOSA, Mary F.
dc.contributor.authorGUO, Xiuqing
dc.contributor.authorHARTWIG, Fernando P.
dc.contributor.authorHORIMOTO, Andrea
dc.contributor.authorKOLCIC, Ivana
dc.contributor.authorLIM, Elise
dc.contributor.authorLIU, Yongmei
dc.contributor.authorMANNING, Alisa K.
dc.contributor.authorMARTEN, Jonathan
dc.contributor.authorMUSANI, Solomon K.
dc.contributor.authorNOORDAM, Raymond
dc.contributor.authorPADMANABHAN, Sandosh
dc.contributor.authorRANKINEN, Tuomo
dc.contributor.authorRICHARD, Melissa A.
dc.contributor.authorRIDKER, Paul M.
dc.contributor.authorSMITH, Albert V.
dc.contributor.authorVOJINOVIC, Dina
dc.contributor.authorZONDERMAN, Alan B.
dc.contributor.authorALVER, Maris
dc.contributor.authorBOISSEL, Mathilde
dc.contributor.authorCHRISTENSEN, Kaare
dc.contributor.authorFREEDMAN, Barry I.
dc.contributor.authorGAO, Chuan
dc.contributor.authorGIULIANINI, Franco
dc.contributor.authorHARRIS, Sarah E.
dc.contributor.authorHE, Meian
dc.contributor.authorHSU, Fang-Chi
dc.contributor.authorKUEHNEL, Brigitte
dc.contributor.authorLAGUZZI, Federica
dc.contributor.authorLI, Xiaoyin
dc.contributor.authorLYYTIKAINEN, Leo-Pekka
dc.contributor.authorNOLTE, Ilja M.
dc.contributor.authorPOVEDA, Alaitz
dc.contributor.authorRAURAMAA, Rainer
dc.contributor.authorRIAZ, Muhammad
dc.contributor.authorROBINO, Antonietta
dc.contributor.authorSOFER, Tamar
dc.contributor.authorTAKEUCHI, Fumihiko
dc.contributor.authorTAYO, Bamidele O.
dc.contributor.authorMOST, Peter J. van der
dc.contributor.authorVERWEIJ, Niek
dc.contributor.authorWARE, Erin B.
dc.contributor.authorWEISS, Stefan
dc.contributor.authorWEN, Wanqing
dc.contributor.authorYANEK, Lisa R.
dc.contributor.authorZHAN, Yiqiang
dc.contributor.authorAMIN, Najaf
dc.contributor.authorARKING, Dan E.
dc.contributor.authorBALLANTYNE, Christie
dc.contributor.authorBOERWINKLE, Eric
dc.contributor.authorBRODY, Jennifer A.
dc.contributor.authorBROECKEL, Ulrich
dc.contributor.authorCAMPBELL, Archie
dc.contributor.authorCANOUIL, Mickael
dc.contributor.authorCHAI, Xiaoran
dc.contributor.authorCHEN, Yii-Der Ida
dc.contributor.authorCHEN, Xu
dc.contributor.authorCHITRALA, Kumaraswamy Naidu
dc.contributor.authorCONCAS, Maria Pina
dc.contributor.authorFAIRE, Ulf de
dc.contributor.authorMUTSERT, Renee de
dc.contributor.authorSILVA, H. Janaka de
dc.contributor.authorVRIES, Paul S. de
dc.contributor.authorDO, Ahn
dc.contributor.authorFAUL, Jessica D.
dc.contributor.authorFISHER, Virginia
dc.contributor.authorFLOYD, James S.
dc.contributor.authorFORRESTER, Terrence
dc.contributor.authorFRIEDLANDER, Yechiel
dc.contributor.authorGIROTTO, Giorgia
dc.contributor.authorGU, C. Charles
dc.contributor.authorHALLMANS, Goeran
dc.contributor.authorHEIKKINEN, Sami
dc.contributor.authorHENG, Chew-Kiat
dc.contributor.authorHOMUTH, Georg
dc.contributor.authorHUNT, Steven
dc.contributor.authorIKRAM, M. Arfan
dc.contributor.authorJACOBS JR., David R.
dc.contributor.authorKAVOUSI, Maryam
dc.contributor.authorKHOR, Chiea Chuen
dc.contributor.authorKILPELAINEN, Tuomas O.
dc.contributor.authorKOH, Woon-Puay
dc.contributor.authorKOMULAINEN, Pirjo
dc.contributor.authorLANGEFELD, Carl D.
dc.contributor.authorLIANG, Jingjing
dc.contributor.authorLIU, Kiang
dc.contributor.authorLIU, Jianjun
dc.contributor.authorLOHMAN, Kurt
dc.contributor.authorMAGI, Reedik
dc.contributor.authorMANICHAIKUL, Ani W.
dc.contributor.authorMCKENZIE, Colin A.
dc.contributor.authorMEITINGER, Thomas
dc.contributor.authorMILANESCHI, Yuri
dc.contributor.authorNAUCK, Matthias
dc.contributor.authorNELSON, Christopher P.
dc.contributor.authorO'CONNELL, Jeffrey R.
dc.contributor.authorPALMER, Nicholette D.
dc.contributor.authorPEREIRA, Alexandre C.
dc.contributor.authorPERLS, Thomas
dc.contributor.authorPETERS, Annette
dc.contributor.authorPOLASEK, Ozren
dc.contributor.authorRAITAKARI, Olli T.
dc.contributor.authorRICE, Kenneth
dc.contributor.authorRICE, Treva K.
dc.contributor.authorRICH, Stephen S.
dc.contributor.authorSABANAYAGAM, Charumathi
dc.contributor.authorSCHREINER, Pamela J.
dc.contributor.authorSHU, Xiao-Ou
dc.contributor.authorSIDNEY, Stephen
dc.contributor.authorSIMS, Mario
dc.contributor.authorSMITH, Jennifer A.
dc.contributor.authorSTARR, John M.
dc.contributor.authorSTRAUCH, Konstantin
dc.contributor.authorTAI, E. Shyong
dc.contributor.authorTAYLOR, Kent D.
dc.contributor.authorTSAI, Michael Y.
dc.contributor.authorUITTERLINDEN, Andre G.
dc.contributor.authorHEEMST, Diana van
dc.contributor.authorWALDENBERGER, Melanie
dc.contributor.authorWANG, Ya-Xing
dc.contributor.authorWEI, Wen-Bin
dc.contributor.authorWILSON, Gregory
dc.contributor.authorXUAN, Deng
dc.contributor.authorYAO, Jie
dc.contributor.authorYU, Caizheng
dc.contributor.authorYUAN, Jian-Min
dc.contributor.authorZHAO, Wei
dc.contributor.authorBECKER, Diane M.
dc.contributor.authorBONNEFOND, Amelie
dc.contributor.authorBOWDEN, Donald W.
dc.contributor.authorCOOPER, Richard S.
dc.contributor.authorDEARY, Ian J.
dc.contributor.authorDIVERS, Jasmin
dc.contributor.authorESKO, Tonu
dc.contributor.authorFRANKS, Paul W.
dc.contributor.authorFROGUEL, Philippe
dc.contributor.authorGIEGER, Christian
dc.contributor.authorJONAS, Jost B.
dc.contributor.authorKATO, Norihiro
dc.contributor.authorLAKKA, Timo A.
dc.contributor.authorLEANDER, Karin
dc.contributor.authorLEHTIMAKI, Terho
dc.contributor.authorMAGNUSSON, Patrik K. E.
dc.contributor.authorNORTH, Kari E.
dc.contributor.authorNTALLA, Ioanna
dc.contributor.authorPENNINX, Brenda
dc.contributor.authorSAMANI, Nilesh J.
dc.contributor.authorSNIEDER, Harold
dc.contributor.authorSPEDICATI, Beatrice
dc.contributor.authorHARST, Pim van der
dc.contributor.authorVOELZKE, Henry
dc.contributor.authorWAGENKNECHT, Lynne E.
dc.contributor.authorWEIR, David R.
dc.contributor.authorWOJCZYNSKI, Mary K.
dc.contributor.authorWU, Tangchun
dc.contributor.authorZHENG, Wei
dc.contributor.authorZHU, Xiaofeng
dc.contributor.authorBOUCHARD, Claude
dc.contributor.authorCHASMAN, Daniel
dc.contributor.authorEVANS, Michele
dc.contributor.authorFOX, Ervin R.
dc.contributor.authorGUDNASON, Vilmundur
dc.contributor.authorHAYWARD, Caroline
dc.contributor.authorHORTA, Bernardo L.
dc.contributor.authorKARDIA, Sharon L. R.
dc.contributor.authorKRIEGER, Jose Eduardo
dc.contributor.authorMOOK-KANAMORI, Dennis O.
dc.contributor.authorPEYSER, Patricia A.
dc.contributor.authorPROVINCE, Michael M.
dc.contributor.authorPSATY, Bruce M.
dc.contributor.authorRUDAN, Igor
dc.contributor.authorSIM, Xueling
dc.contributor.authorSMITH, Blair H.
dc.contributor.authorDAM, Rob M. van
dc.contributor.authorDUIJN, Cornelia M. van
dc.contributor.authorWONG, Tien Yin
dc.contributor.authorARNETT, Donna K.
dc.contributor.authorRAO, Dabeeru C.
dc.contributor.authorGAUDERMAN, James
dc.contributor.authorLIU, Ching-Ti
dc.contributor.authorMORRISON, Alanna C.
dc.contributor.authorROTTER, Jerome I.
dc.contributor.authorFORNAGE, Myriam
dc.date.accessioned2024-02-15T14:40:21Z
dc.date.available2024-02-15T14:40:21Z
dc.date.issued2023
dc.description.abstractIntroduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes.Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment interactions in up to 226,315 individuals from five population groups. We considered two educational attainment variables: ""Some College"" (yes/no, for any education beyond high school) and ""Graduated College"" (yes/no, for completing a 4-year college degree). Genome-wide significant (p < 5 x 10(-8)) and suggestive (p < 1 x 10(-6)) variants were identified in Stage 1 (in up to 108,784 individuals) through genome-wide analysis, and those variants were followed up in Stage 2 studies (in up to 117,531 individuals).Results: In combined analysis of Stages 1 and 2, we identified 18 novel lipid loci (nine for LDL, seven for HDL, and two for TG) by two degree-of-freedom (2 DF) joint tests of main and interaction effects. Four loci showed significant interaction with educational attainment. Two loci were significant only in cross-population analyses. Several loci include genes with known or suggested roles in adipose (FOXP1, MBOAT4, SKP2, STIM1, STX4), brain (BRI3, FILIP1, FOXP1, LINC00290, LMTK2, MBOAT4, MYO6, SENP6, SRGAP3, STIM1, TMEM167A, TMEM30A), and liver (BRI3, FOXP1) biology, highlighting the potential importance of brain-adipose-liver communication in the regulation of lipid metabolism. An investigation of the potential druggability of genes in identified loci resulted in five gene targets shown to interact with drugs approved by the Food and Drug Administration, including genes with roles in adipose and brain tissue.Discussion: Genome-wide interaction analysis of educational attainment identified novel lipid loci not previously detected by analyses limited to main genetic effects.eng
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.description.sponsorshipU.S. National Heart, Lung, and Blood Institute (NHLBI), the National Institutes of Health [R01HL118305, R01HL156991]
dc.description.sponsorshipIntramural Research Program of the National Human Genome Research Institute, National Institutes of Health
dc.description.sponsorshipNHLBI [K25HL121091]
dc.identifier.citationFRONTIERS IN GENETICS, v.14, article ID 1235337, 16p, 2023
dc.identifier.doi10.3389/fgene.2023.1235337
dc.identifier.eissn1664-8021
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/57899
dc.language.isoeng
dc.publisherFRONTIERS MEDIA SAeng
dc.relation.ispartofFrontiers in Genetics
dc.rightsopenAccesseng
dc.rights.holderCopyright FRONTIERS MEDIA SAeng
dc.subjecteducational attainmenteng
dc.subjectlipidseng
dc.subjectcholesteroleng
dc.subjecttriglycerideseng
dc.subjectgenome-wide association studyeng
dc.subjectmeta-analysiseng
dc.subject.othercoronary-heart-diseaseeng
dc.subject.otherenvironment interactioneng
dc.subject.otheradipocyte differentiationeng
dc.subject.othersocioeconomic-statuseng
dc.subject.otherlipoprotein-lipaseeng
dc.subject.otherinsulin-resistanceeng
dc.subject.othertransgenic miceeng
dc.subject.otheradipose-tissueeng
dc.subject.otherblood-pressureeng
dc.subject.otherrisk-factorseng
dc.subject.wosGenetics & Heredityeng
dc.titleGene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid locieng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryCatar
hcfmusp.affiliation.countryIsrael
hcfmusp.affiliation.countryJamaica
hcfmusp.affiliation.countrySri Lanka
hcfmusp.affiliation.countryJapão
hcfmusp.affiliation.countryItália
hcfmusp.affiliation.countryFinlândia
hcfmusp.affiliation.countrySuécia
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hcfmusp.author.externalFUENTES, Lisa de las:Washington Univ, Sch Med, Dept Med, Cardiovasc Div, St Louis, MO 63110 USA; Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
hcfmusp.author.externalSCHWANDER, Karen L. M.:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA; Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA
hcfmusp.author.externalBROWN, Michael R.:Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci, Human Genet Ctr, Houston, TX 77030 USA
hcfmusp.author.externalBENTLEY, Amy R.:NHGRI, Ctr Res Genom & Global Hlth, NIH, Bethesda, MD 20892 USA
hcfmusp.author.externalWINKLER, Thomas W.:Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany
hcfmusp.author.externalSUNG, Yun Ju:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA; Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
hcfmusp.author.externalMUNROE, Patricia B.:Queen Mary Univ London, Clin Pharmacol, London, England; Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England
hcfmusp.author.externalMILLER, Clint L.:Univ Virginia, Dept Publ Hlth Sci, Ctr Publ Hlth Genom, Charlottesville, VA USA; Univ Virginia, Dept Publ Hlth Sci, Biochem & Mol Genet, Charlottesville, VA USA; Univ Virginia, Dept Biochem & Mol Genet, Charlottesville, VA USA
hcfmusp.author.externalASCHARD, Hugo:Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA; Univ Lille, Inst Pasteur Lille, Dept Genomes & Genet, Lille, France
hcfmusp.author.externalASLIBEKYAN, Stella:Univ Alabama Birmingham, Sch Publ Hlth, Epidemiol, Birmingham, AL 35294 USA
hcfmusp.author.externalBARTZ, Traci M.:Univ Washington, Cardiovasc Hlth Res Unit, Seattle, WA 98195 USA; Univ Washington, Dept Biostat, Seattle, WA 98195 USA
hcfmusp.author.externalBIELAK, Lawrence F.:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
hcfmusp.author.externalCHAI, Jin Fang:Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore
hcfmusp.author.externalCHENG, Ching-Yu:Singapore Natl Eye Ctr, Singapore Eye Res Inst, 20Ocular Epidemiol, Singapore, Singapore; Duke Natl Univ Singapore, Ophthalmol & Visual Sci Acad Clin Program, Sch Med, Singapore, Singapore
hcfmusp.author.externalDORAJOO, Rajkumar:Agcy Sci Res & Technol, Genome Inst Singapore, Singapore, Singapore
hcfmusp.author.externalFEITOSA, Mary F.:Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA
hcfmusp.author.externalGUO, Xiuqing:Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Lundquist Inst Biomed Innovat, Dept Pediat, Los Angeles, CA USA
hcfmusp.author.externalHARTWIG, Fernando P.:Univ Fed Pelotas, Postgrad Programme Epidemiol, Fac Med, Pelotas, RS, Brazil; Univ Bristol, Med Res Council, Integrat Epidemiol Unit, Bristol, Avon, England
hcfmusp.author.externalHORIMOTO, Andrea:Univ Sao Paulo, Inst Heart, Lab Genet & Mol Cardiol, Med Sch, Sao Paulo, SP, Brazil
hcfmusp.author.externalKOLCIC, Ivana:Univ Split, Sch Med, Split, Croatia; Algebra Univ Coll, Zagreb, Croatia
hcfmusp.author.externalLIM, Elise:Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA
hcfmusp.author.externalLIU, Yongmei:Duke Univ, Sch Med, Dept Med, Div Cardiol,Duke Mol Physiol Inst, Durham, NC 27706 USA
hcfmusp.author.externalMANNING, Alisa K.:Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA; Harvard Med Sch, Dept Med, Boston, MA 02115 USA
hcfmusp.author.externalMARTEN, Jonathan:Univ Edinburgh, Inst Genet & Canc, Med Res Council, Human Genet Unit, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalMUSANI, Solomon K.:Univ Mississippi, Med Ctr, Dept Med, Jackson Heart Study, Jackson, MS 39216 USA
hcfmusp.author.externalNOORDAM, Raymond:Leiden Univ, Dept Internal Med, Sect Gerontol & Geriatr, Med Ctr, Leiden, Netherlands
hcfmusp.author.externalPADMANABHAN, Sandosh:Univ Glasgow, Inst Cardiovasc & Med Sci, Glasgow, Lanark, Scotland
hcfmusp.author.externalRANKINEN, Tuomo:Pennington Biomed Res Ctr, Human Genom Lab, 6400 Perkins Rd, Baton Rouge, LA 70808 USA
hcfmusp.author.externalRICHARD, Melissa A.:Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA
hcfmusp.author.externalRIDKER, Paul M.:Pennington Biomed Res Ctr, Human Genom Lab, 6400 Perkins Rd, Baton Rouge, LA 70808 USA; Harvard Med Sch, Boston, MA 02115 USA
hcfmusp.author.externalSMITH, Albert V.:Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA; Iceland Heart Assoc, Kopavogur, Iceland
hcfmusp.author.externalVOJINOVIC, Dina:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands; Leiden Univ, Dept Biomed Data Sci, Mol Epidemiol, Med Ctr, Leiden, Netherlands
hcfmusp.author.externalZONDERMAN, Alan B.:NIA, Lab Epidemiol & Populat Sci, NIH, Baltimore, MD 21224 USA; NIH, Baltimore, MD USA
hcfmusp.author.externalALVER, Maris:Univ Tartu, Estonian Genome Ctr, Insititute Genom, Tartu, Estonia
hcfmusp.author.externalBOISSEL, Mathilde:Inst Pasteur, European Genom Inst Diabet, Lille, France; Univ Lille, Lille Univ Hosp, Lille, France
hcfmusp.author.externalCHRISTENSEN, Kaare:Univ Southern Denmark, Dept Publ Hlth, Unit Epidemiol Biostat & Biodemog, Odense, Denmark
hcfmusp.author.externalFREEDMAN, Barry I.:Wake Forest Sch Med, Dept Internal Med, Nephrol Div, Winston Salem, NC 27101 USA
hcfmusp.author.externalGAO, Chuan:Wake Forest Sch Med, Mol Genet & Genom Program, Winston Salem, NC 27101 USA
hcfmusp.author.externalGIULIANINI, Franco:Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA
hcfmusp.author.externalHARRIS, Sarah E.:Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland; Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalHE, Meian:Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, Dept Occupat & Environm Hlth, Wuhan, Peoples R China; Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, State Key Lab Environm Hlth Incubating, Wuhan, Peoples R China
hcfmusp.author.externalHSU, Fang-Chi:Wake Forest Univ, Bowman Gray Sch Med, Dept Biostat & Data Sci, Div Publ Hlth Sci, Winston Salem, NC USA
hcfmusp.author.externalKUEHNEL, Brigitte:German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany; German Res Ctr Environm Hlth, Inst Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany
hcfmusp.author.externalLAGUZZI, Federica:Karolinska Inst, Inst Environm Med, Cardiovasc & Nutr Epidemiol, Stockholm, Sweden
hcfmusp.author.externalLI, Xiaoyin:Dept Populat & Quantitat Hlth Sci, Cleveland, OH USA; St Cloud State Univ, Dept Math & Stat, St Cloud, MN 56301 USA
hcfmusp.author.externalLYYTIKAINEN, Leo-Pekka:Univ Tampere, Dept Clin Chem, Tampere, Finland; Univ Tampere, Finnish Cardiovasc Res Ctr, Tampere, Finland
hcfmusp.author.externalNOLTE, Ilja M.:Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Unit Genet Epidemiol & Bioinformat, Groningen, Netherlands
hcfmusp.author.externalPOVEDA, Alaitz:Lund Univ, Skane Univ Hosp, Dept Clin Sci, Genet & Mol Epidemiol Unit, Malmo, Sweden
hcfmusp.author.externalRAURAMAA, Rainer:Kuopio Res Inst Exercise Med, Kuopio, Finland
hcfmusp.author.externalRIAZ, Muhammad:Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England; Glenfield Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
hcfmusp.author.externalROBINO, Antonietta:IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy
hcfmusp.author.externalSOFER, Tamar:Harvard Univ, Brigham & Womens Hosp, Dept Med, Biostat, Boston, MA 02115 USA
hcfmusp.author.externalTAKEUCHI, Fumihiko:Natl Ctr Global Hlth & Med, Res Inst, Dept Gene Diagnost & Therapeut, Tokyo, Japan
hcfmusp.author.externalTAYO, Bamidele O.:Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA
hcfmusp.author.externalMOST, Peter J. van der:Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands
hcfmusp.author.externalVERWEIJ, Niek:Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands
hcfmusp.author.externalWARE, Erin B.:Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI USA
hcfmusp.author.externalWEISS, Stefan:Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany; Univ Greifswald, Greifswald, Germany; German Ctr Cardiovasc Res, Greifswald, Germany
hcfmusp.author.externalWEN, Wanqing:Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA
hcfmusp.author.externalYANEK, Lisa R.:Johns Hopkins Univ, Sch Med, Dept Med, Div Gen Internal Med, Baltimore, MD 21205 USA
hcfmusp.author.externalZHAN, Yiqiang:Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
hcfmusp.author.externalAMIN, Najaf:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands
hcfmusp.author.externalARKING, Dan E.:Johns Hopkins Univ, Sch Med, McKusick Nathans Inst, Dept Genet Med, Baltimore, MD USA
hcfmusp.author.externalBALLANTYNE, Christie:Baylor Coll Med, Sect Cardiovasc Res, Houston, TX 77030 USA; Houston Methodist Debakey Heart & Vasc Ctr, Houston, TX USA
hcfmusp.author.externalBOERWINKLE, Eric:Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci, Human Genet Ctr, Houston, TX 77030 USA; Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA
hcfmusp.author.externalBRODY, Jennifer A.:Univ Washington, Cardiovasc Hlth Res Unit, Seattle, WA 98195 USA
hcfmusp.author.externalBROECKEL, Ulrich:Med Coll Wisconsin, Dept Pediat, Sect Genom Pediat, 8701 Watertown Plank Rd, Milwaukee, WI 53226 USA
hcfmusp.author.externalCAMPBELL, Archie:Univ Edinburgh, Inst Genet & Canc, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland; Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalCANOUIL, Mickael:Inst Pasteur, European Genom Inst Diabet, Lille, France; Univ Lille, Lille Univ Hosp, Lille, France
hcfmusp.author.externalCHAI, Xiaoran:Singapore Natl Eye Ctr, Singapore Eye Res Inst, Data Sci Unit, Singapore, Singapore
hcfmusp.author.externalCHEN, Yii-Der Ida:Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Lundquist Inst Biomed Innovat, Dept Pediat, Los Angeles, CA USA
hcfmusp.author.externalCHEN, Xu:Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
hcfmusp.author.externalCHITRALA, Kumaraswamy Naidu:NIA, Lab Epidemiol & Populat Sci, NIH, Baltimore, MD 21224 USA
hcfmusp.author.externalCONCAS, Maria Pina:IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy
hcfmusp.author.externalFAIRE, Ulf de:Karolinska Inst, Inst Environm Med, Cardiovasc & Nutr Epidemiol, Stockholm, Sweden
hcfmusp.author.externalMUTSERT, Renee de:Leiden Univ, Dept Clin Epidemiol, Med Ctr, Leiden, Netherlands
hcfmusp.author.externalSILVA, H. Janaka de:Univ Kelaniya, Dept Med, Fac Med, Ragama, Sri Lanka
hcfmusp.author.externalVRIES, Paul S. de:Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci, Human Genet Ctr, Houston, TX 77030 USA
hcfmusp.author.externalDO, Ahn:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA; Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA
hcfmusp.author.externalFAUL, Jessica D.:Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI USA
hcfmusp.author.externalFISHER, Virginia:Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA
hcfmusp.author.externalFLOYD, James S.:Univ Washington, Cardiovasc Hlth Res Unit, Seattle, WA 98195 USA
hcfmusp.author.externalFORRESTER, Terrence:Univ West Indies, Trop Med Res Inst, Mona, Jamaica
hcfmusp.author.externalFRIEDLANDER, Yechiel:Hebrew Univ Jerusalem, Braun Sch Publ Hlth, Hadassah Med Ctr, Jerusalem, Israel
hcfmusp.author.externalGIROTTO, Giorgia:IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy
hcfmusp.author.externalGU, C. Charles:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
hcfmusp.author.externalHALLMANS, Goeran:Umea Univ, Dept Publ Hlth & Clin Med, Sect Nutr Res, Umea, Sweden
hcfmusp.author.externalHEIKKINEN, Sami:Univ Eastern Finland, Sch Med, Inst Biomed, Kuopio, Finland
hcfmusp.author.externalHENG, Chew-Kiat:Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore, Singapore; Natl Univ Hlth Syst, Khoo Teck Puat Natl Univ Childrens Med Inst, Singapore, Singapore
hcfmusp.author.externalHOMUTH, Georg:Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany; Univ Greifswald, Greifswald, Germany
hcfmusp.author.externalHUNT, Steven:Univ Utah, Dept Internal Med, Salt Lake City, UT 84112 USA; Weill Cornell Med Qatar, Dept Genet Med, Doha, Qatar
hcfmusp.author.externalIKRAM, M. Arfan:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands
hcfmusp.author.externalJACOBS JR., David R.:Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA
hcfmusp.author.externalKAVOUSI, Maryam:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands
hcfmusp.author.externalKHOR, Chiea Chuen:Agcy Sci Res & Technol, Genome Inst Singapore, Singapore, Singapore
hcfmusp.author.externalKILPELAINEN, Tuomas O.:Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark; Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY 10029 USA
hcfmusp.author.externalKOH, Woon-Puay:Natl Univ Singapore, Yong Loo Lin Sch Med, Hlth Longev Translat Res Programme, Singapore, Singapore; ASTAR, Singapore Inst Clin Sci, Singapore, Singapore
hcfmusp.author.externalKOMULAINEN, Pirjo:Kuopio Res Inst Exercise Med, Kuopio, Finland
hcfmusp.author.externalLANGEFELD, Carl D.:Wake Forest Univ, Bowman Gray Sch Med, Dept Biostat & Data Sci, Div Publ Hlth Sci, Winston Salem, NC USA
hcfmusp.author.externalLIANG, Jingjing:Dept Populat & Quantitat Hlth Sci, Cleveland, OH USA
hcfmusp.author.externalLIU, Kiang:Northwestern Univ, Dept Prevent Med, Feinberg Sch Med, Epidemiol, Chicago, IL 60611 USA
hcfmusp.author.externalLIU, Jianjun:Agcy Sci Res & Technol, Genome Inst Singapore, Singapore, Singapore
hcfmusp.author.externalLOHMAN, Kurt:Duke Univ, Sch Med, Dept Med, Div Cardiol,Duke Mol Physiol Inst, Durham, NC 27706 USA
hcfmusp.author.externalMAGI, Reedik:Univ Tartu, Estonian Genome Ctr, Insititute Genom, Tartu, Estonia
hcfmusp.author.externalMANICHAIKUL, Ani W.:Univ Virginia, Dept Publ Hlth Sci, Ctr Publ Hlth Genom, Charlottesville, VA USA
hcfmusp.author.externalMCKENZIE, Colin A.:Univ West Indies, Trop Med Res Inst, Mona, Jamaica
hcfmusp.author.externalMEITINGER, Thomas:German Res Ctr Environm Hlth, Inst Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany; Tech Univ Munich, Inst Human Genet, Munich, Germany
hcfmusp.author.externalMILANESCHI, Yuri:Vrije Univ Amsterdam Med Ctr, Psychiat, Amsterdam, Netherlands
hcfmusp.author.externalNAUCK, Matthias:German Ctr Cardiovasc Res, Greifswald, Germany; Univ Med Greifswald, Inst Clin Chem & Lab Med, Greifswald, Germany
hcfmusp.author.externalNELSON, Christopher P.:Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England; Glenfield Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
hcfmusp.author.externalO'CONNELL, Jeffrey R.:Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA; Univ Maryland, Sch Med, Program Personalized & Genom Med, Baltimore, MD 21201 USA
hcfmusp.author.externalPALMER, Nicholette D.:Wake Forest Sch Med, Dept Biochem, Winston Salem, NC 27101 USA
hcfmusp.author.externalPERLS, Thomas:Boston Univ, Sch Med, Dept Med, Geriatr Sect, Boston, MA 02118 USA
hcfmusp.author.externalPETERS, Annette:German Res Ctr Environm Hlth, Inst Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany; German Ctr Cardiovasc Res, Neuherberg, Germany
hcfmusp.author.externalPOLASEK, Ozren:Univ Split, Sch Med, Split, Croatia; Algebra Univ Coll, Zagreb, Croatia
hcfmusp.author.externalRAITAKARI, Olli T.:Univ Turku, Ctr Populat Hlth Res, Turku, Finland; Turku Univ Hosp, Turku, Finland; Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland; Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland
hcfmusp.author.externalRICE, Kenneth:Univ Washington, Dept Biostat, Seattle, WA 98195 USA
hcfmusp.author.externalRICE, Treva K.:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
hcfmusp.author.externalRICH, Stephen S.:Univ Virginia, Dept Publ Hlth Sci, Ctr Publ Hlth Genom, Charlottesville, VA USA
hcfmusp.author.externalSABANAYAGAM, Charumathi:Singapore Natl Eye Ctr, Singapore Eye Res Inst, 20Ocular Epidemiol, Singapore, Singapore; Duke Natl Univ Singapore, Ophthalmol & Visual Sci Acad Clin Program, Sch Med, Singapore, Singapore
hcfmusp.author.externalSCHREINER, Pamela J.:Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA
hcfmusp.author.externalSHU, Xiao-Ou:Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA
hcfmusp.author.externalSIDNEY, Stephen:Kaiser Permanente Northern Calif, Div Res, Oakland, CA USA
hcfmusp.author.externalSIMS, Mario:Univ Mississippi, Med Ctr, Dept Med, Jackson Heart Study, Jackson, MS 39216 USA
hcfmusp.author.externalSMITH, Jennifer A.:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA; Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI USA
hcfmusp.author.externalSTARR, John M.:Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland; Univ Edinburgh, Alzheimer Scotland Dementia Res Ctr, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalSTRAUCH, Konstantin:Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany; Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Munich, Germany
hcfmusp.author.externalTAI, E. Shyong:Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore; Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore; Duke Natl Univ Singapore, Med Sch, Singapore, Singapore
hcfmusp.author.externalTAYLOR, Kent D.:Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Lundquist Inst Biomed Innovat, Dept Pediat, Los Angeles, CA USA
hcfmusp.author.externalTSAI, Michael Y.:Dept Lab Med & Pathol, Minneapolis, MN USA
hcfmusp.author.externalUITTERLINDEN, Andre G.:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands; Univ Med Ctr, Dept Internal Med, Erasmus MC, Rotterdam, Netherlands
hcfmusp.author.externalHEEMST, Diana van:Leiden Univ, Dept Internal Med, Sect Gerontol & Geriatr, Med Ctr, Leiden, Netherlands
hcfmusp.author.externalWALDENBERGER, Melanie:German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany; German Res Ctr Environm Hlth, Inst Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany; German Ctr Cardiovasc Res DZHK, Partner Site Munich Heart Alliance, Munich, Germany
hcfmusp.author.externalWANG, Ya-Xing:Capital Med Univ, Beijing Inst Ophthalmol, Beijing Tongren Hosp, Beijing Ophthalmol & Visual Sci Key Lab,Eye Ctr, Beijing, Peoples R China
hcfmusp.author.externalWEI, Wen-Bin:Capital Med Univ, Beijing Inst Ophthalmol, Beijing Tongren Hosp, Beijing Ophthalmol & Visual Sci Key Lab,Eye Ctr, Beijing, Peoples R China
hcfmusp.author.externalWILSON, Gregory:Jackson State Univ, Sch Publ, Jackson Heart Study Grad Training Ctr, Jackson, MS USA
hcfmusp.author.externalXUAN, Deng:Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA
hcfmusp.author.externalYAO, Jie:Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Lundquist Inst Biomed Innovat, Dept Pediat, Los Angeles, CA USA
hcfmusp.author.externalYU, Caizheng:Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, Dept Occupat & Environm Hlth, Wuhan, Peoples R China; Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, State Key Lab Environm Hlth Incubating, Wuhan, Peoples R China
hcfmusp.author.externalYUAN, Jian-Min:Univ Pittsburgh, Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA; Univ Pittsburgh Med Ctr UPMC, Div Canc Control & Populat Sci, Hillman Canc Ctr, Pittsburgh, PA USA
hcfmusp.author.externalZHAO, Wei:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
hcfmusp.author.externalBECKER, Diane M.:Johns Hopkins Univ, Sch Med, Dept Med, Div Gen Internal Med, Baltimore, MD 21205 USA
hcfmusp.author.externalBONNEFOND, Amelie:Inst Pasteur, European Genom Inst Diabet, Lille, France; Univ Lille, Lille Univ Hosp, Lille, France; Imperial Coll London, Dept Metab Digest & Reprod, London, England
hcfmusp.author.externalBOWDEN, Donald W.:Wake Forest Sch Med, Dept Biochem, Winston Salem, NC 27101 USA
hcfmusp.author.externalCOOPER, Richard S.:Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA
hcfmusp.author.externalDEARY, Ian J.:Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland; Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalDIVERS, Jasmin:Wake Forest Univ, Bowman Gray Sch Med, Dept Biostat & Data Sci, Div Publ Hlth Sci, Winston Salem, NC USA
hcfmusp.author.externalESKO, Tonu:Univ Tartu, Estonian Genome Ctr, Insititute Genom, Tartu, Estonia; MIT, Broad Inst, Boston, MA USA; Harvard Univ, Boston, MA 02115 USA
hcfmusp.author.externalFRANKS, Paul W.:Lund Univ, Skane Univ Hosp, Dept Clin Sci, Genet & Mol Epidemiol Unit, Malmo, Sweden; Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden; Harvard Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA
hcfmusp.author.externalFROGUEL, Philippe:Inst Pasteur, European Genom Inst Diabet, Lille, France; Univ Lille, Lille Univ Hosp, Lille, France; Imperial Coll London, Dept Metab Digest & Reprod, London, England
hcfmusp.author.externalGIEGER, Christian:German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany; German Ctr Diabet Res, Neuherberg, Germany
hcfmusp.author.externalJONAS, Jost B.:Capital Med Univ, Beijing Inst Ophthalmol, Beijing Tongren Hosp, Beijing Ophthalmol & Visual Sci Key Lab,Eye Ctr, Beijing, Peoples R China; Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Mannheim, Germany; Inst Mol & Clin Ophthalmol, Basel, Switzerland
hcfmusp.author.externalKATO, Norihiro:Natl Ctr Global Hlth & Med, Res Inst, Dept Gene Diagnost & Therapeut, Tokyo, Japan
hcfmusp.author.externalLAKKA, Timo A.:Kuopio Res Inst Exercise Med, Kuopio, Finland; Univ Eastern Finland, Sch Med, Inst Biomed, Kuopio, Finland; Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, Kuopio, Finland
hcfmusp.author.externalLEANDER, Karin:Karolinska Inst, Inst Environm Med, Cardiovasc & Nutr Epidemiol, Stockholm, Sweden
hcfmusp.author.externalLEHTIMAKI, Terho:Univ Tampere, Dept Clin Chem, Tampere, Finland; Univ Tampere, Finnish Cardiovasc Res Ctr, Tampere, Finland
hcfmusp.author.externalMAGNUSSON, Patrik K. E.:Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
hcfmusp.author.externalNORTH, Kari E.:Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27515 USA
hcfmusp.author.externalNTALLA, Ioanna:Queen Mary Univ London, Clin Pharmacol, London, England; Bristol Myers Squibb, Celgene, Mississauga, ON, Canada
hcfmusp.author.externalPENNINX, Brenda:Vrije Univ Amsterdam Med Ctr, Psychiat, Amsterdam, Netherlands
hcfmusp.author.externalSAMANI, Nilesh J.:Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England; Glenfield Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
hcfmusp.author.externalSNIEDER, Harold:Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Unit Genet Epidemiol & Bioinformat, Groningen, Netherlands
hcfmusp.author.externalSPEDICATI, Beatrice:Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy
hcfmusp.author.externalHARST, Pim van der:Univ Utrecht, Univ Med Ctr Utrecht, Dept Cardiol, Div Heart & Lungs, Utrecht, Netherlands
hcfmusp.author.externalVOELZKE, Henry:German Ctr Cardiovasc Res, Greifswald, Germany; Univ Med Greifswald, Inst Community Med, Greifswald, Germany
hcfmusp.author.externalWAGENKNECHT, Lynne E.:Wake Forest Univ, Bowman Gray Sch Med, Dept Biostat & Data Sci, Div Publ Hlth Sci, Winston Salem, NC USA
hcfmusp.author.externalWEIR, David R.:Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI USA
hcfmusp.author.externalWOJCZYNSKI, Mary K.:Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA
hcfmusp.author.externalWU, Tangchun:Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, Dept Occupat & Environm Hlth, Wuhan, Peoples R China; Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, State Key Lab Environm Hlth Incubating, Wuhan, Peoples R China
hcfmusp.author.externalZHENG, Wei:Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA
hcfmusp.author.externalZHU, Xiaofeng:Dept Populat & Quantitat Hlth Sci, Cleveland, OH USA
hcfmusp.author.externalBOUCHARD, Claude:Pennington Biomed Res Ctr, Human Genom Lab, 6400 Perkins Rd, Baton Rouge, LA 70808 USA
hcfmusp.author.externalCHASMAN, Daniel:Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA; Harvard Med Sch, Boston, MA 02115 USA
hcfmusp.author.externalEVANS, Michele:NIA, Lab Epidemiol & Populat Sci, NIH, Baltimore, MD 21224 USA; NIA, NIH, Bethesda, MD 20892 USA
hcfmusp.author.externalFOX, Ervin R.:Univ Mississippi, Med Ctr, Dept Med, Div Cardiol, Jackson, MS 39216 USA
hcfmusp.author.externalGUDNASON, Vilmundur:Iceland Heart Assoc, Kopavogur, Iceland; Univ Iceland, Fac Med, Reykjavik, Iceland
hcfmusp.author.externalHAYWARD, Caroline:Univ Edinburgh, Inst Genet & Canc, Med Res Council, Human Genet Unit, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalHORTA, Bernardo L.:Univ Fed Pelotas, Postgrad Programme Epidemiol, Fac Med, Pelotas, RS, Brazil
hcfmusp.author.externalKARDIA, Sharon L. R.:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
hcfmusp.author.externalMOOK-KANAMORI, Dennis O.:Leiden Univ, Dept Clin Epidemiol, Med Ctr, Leiden, Netherlands; Leiden Univ, Med Ctr, Dept Publ Hlth & Primary Care, Leiden, Netherlands
hcfmusp.author.externalPEYSER, Patricia A.:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
hcfmusp.author.externalPROVINCE, Michael M.:Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA
hcfmusp.author.externalPSATY, Bruce M.:Univ Washington, Cardiovasc Hlth Res Unit, Seattle, WA 98195 USA; Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA; Univ Washington, Dept Hlth Syst & Populat Hlth, Seattle, WA 98195 USA
hcfmusp.author.externalRUDAN, Igor:Univ Edinburgh, Usher Inst, Ctr Global Hlth, Edinburgh, Midlothian, Scotland
hcfmusp.author.externalSIM, Xueling:Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore
hcfmusp.author.externalSMITH, Blair H.:Univ Dundee, Ninewells Hosp & Med Sch, Div Populat Hlth & Genom, Dundee, Scotland
hcfmusp.author.externalDAM, Rob M. van:Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore; Natl Univ Hlth Syst, Singapore, Singapore; George Washington Univ, Dept Exercise & Nutr Sci, Milken Inst Sch Publ Hlth, Washington, DC USA
hcfmusp.author.externalDUIJN, Cornelia M. van:Univ Med Ctr, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands; Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England
hcfmusp.author.externalWONG, Tien Yin:Singapore Natl Eye Ctr, Singapore Eye Res Inst, 20Ocular Epidemiol, Singapore, Singapore; Duke Natl Univ Singapore, Ophthalmol & Visual Sci Acad Clin Program, Sch Med, Singapore, Singapore
hcfmusp.author.externalARNETT, Donna K.:Univ Kentucky, Coll Publ Hlth, Deans Off, Lexington, KY USA
hcfmusp.author.externalRAO, Dabeeru C.:Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
hcfmusp.author.externalGAUDERMAN, James:Univ Southern Calif, Div Biostat Populat & Publ Hlth Sci, Los Angeles, CA 90007 USA
hcfmusp.author.externalLIU, Ching-Ti:Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA
hcfmusp.author.externalMORRISON, Alanna C.:Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci, Human Genet Ctr, Houston, TX 77030 USA
hcfmusp.author.externalROTTER, Jerome I.:Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Lundquist Inst Biomed Innovat, Dept Pediat, Los Angeles, CA USA
hcfmusp.author.externalFORNAGE, Myriam:Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci, Human Genet Ctr, Houston, TX 77030 USA; Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcALEXANDRE DA COSTA PEREIRA
hcfmusp.contributor.author-fmusphcJOSE EDUARDO KRIEGER
hcfmusp.description.articlenumber1235337
hcfmusp.description.volume14
hcfmusp.origemWOS
hcfmusp.origem.pubmed38028628
hcfmusp.origem.scopus2-s2.0-85177065494
hcfmusp.origem.wosWOS:001106059400001
hcfmusp.publisher.cityLAUSANNEeng
hcfmusp.publisher.countrySWITZERLANDeng
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