First brazilian consensus of advanced prostate cancer: recommendations for clinical practice

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSASSE, Andre Deeke
dc.contributor.authorWIERMANN, Evanius Garcia
dc.contributor.authorHERCHENHORN, Daniel
dc.contributor.authorBASTOS, Diogo Assed
dc.contributor.authorSCHUTZ, Fabio A.
dc.contributor.authorMALUF, Fernando Cotait
dc.contributor.authorCOURA FILHO, George
dc.contributor.authorMORBECK, Igor Alexandre Protzner
dc.contributor.authorCERCI, Juliano J.
dc.contributor.authorSMALETZ, Oren
dc.contributor.authorLIMA, Volney Soares
dc.contributor.authorADAMY JR., Ari
dc.contributor.authorCAMPOS, Franz Santos de
dc.contributor.authorCARVALHAL, Gustavo Franco
dc.contributor.authorCEZAR, Leandro Casemiro
dc.contributor.authorDALL'OGLIO, Marcos Francisco
dc.contributor.authorSADI, Marcus Vinicius
dc.contributor.authorREIS, Rodolfo Borges dos
dc.contributor.authorNOGUEIRA, Lucas
dc.date.accessioned2017-08-17T19:12:21Z
dc.date.available2017-08-17T19:12:21Z
dc.date.issued2017
dc.description.abstractIntroduction: Prostate cancer still represents a major cause of morbidity, and still about 20% of men with the disease are diagnosed or will progress to the advanced stage without the possibility of curative treatment. Despite the recent advances in scientific and technological knowledge and the availability of new therapies, there is still considerable heterogeneity in the therapeutic approaches for metastatic prostate cancer. Objectives: This article presents a summary of the I Brazilian Consensus on Advanced Prostate Cancer, conducted by the Brazilian Society of Urology and Brazilian Society of Clinical Oncology. Materials and Methods: Experts were selected by the medical societies involved. Forty issues regarding controversial issues in advanced disease were previously elaborated. The panel met for consensus, with a threshold established for 2/3 of the participants. Results and Conclusions: The treatment of advanced prostate cancer is complex, due to the existence of a large number of therapies, with different response profiles and toxicities. The panel addressed recommendations on preferred choice of therapies, indicators that would justify their change, and indicated some strategies for better sequencing of treatment in order to maximize the potential for disease control with the available therapeutic arsenal. The lack of consensus on some topics clearly indicates the absence of strong evidence for some decisions.
dc.description.indexMEDLINE
dc.description.sponsorshipBrazilian Society of Clinical Oncology
dc.description.sponsorshipBrazilian Society of Urology
dc.identifier.citationINTERNATIONAL BRAZ J UROL, v.43, n.3, p.407-415, 2017
dc.identifier.doi10.1590/S1677-5538.IBJU.2016.0490
dc.identifier.eissn1677-6119
dc.identifier.issn1677-5538
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/21200
dc.language.isoeng
dc.publisherBRAZILIAN SOC UROL
dc.relation.ispartofInternational Braz J Urol
dc.rightsopenAccess
dc.rights.holderCopyright BRAZILIAN SOC UROL
dc.subjectProstatic Neoplasms
dc.subjectPractice Guideline [Publication Type]
dc.subjectDiagnosis
dc.subject.otherplacebo-controlled phase-3
dc.subject.otherabiraterone acetate
dc.subject.othersurvival analysis
dc.subject.otherplus prednisone
dc.subject.otherdouble-blind
dc.subject.otheropen-label
dc.subject.otherenzalutamide
dc.subject.otherchemotherapy
dc.subject.otherdocetaxel
dc.subject.othermitoxantrone
dc.subject.wosUrology & Nephrology
dc.titleFirst brazilian consensus of advanced prostate cancer: recommendations for clinical practice
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalSASSE, Andre Deeke:Univ Estadual Campinas, Clin Med, Campinas, SP, Brazil
hcfmusp.author.externalWIERMANN, Evanius Garcia:Soc Brasileira Oncol Clin, Belo Horizonte, MG, Brazil
hcfmusp.author.externalHERCHENHORN, Daniel:INCA, Inst Nacl Canc, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalSCHUTZ, Fabio A.:Beneficiencia Portuguesa Sao Paulo, Sao Paulo, SP, Brazil
hcfmusp.author.externalMALUF, Fernando Cotait:Beneficiencia Portuguesa Sao Paulo, Sao Paulo, SP, Brazil; Hosp Israelita Albert Einstein, Dept Oncol, Sao Paulo, SP, Brazil
hcfmusp.author.externalMORBECK, Igor Alexandre Protzner:Univ Catolica Brasilia, Taguatinga, DF, Brazil
hcfmusp.author.externalCERCI, Juliano J.:Univ Sao Paulo, Sao Paulo, SP, Brazil
hcfmusp.author.externalSMALETZ, Oren:Hosp Israelita Albert Einstein, Dept Oncol, Sao Paulo, SP, Brazil
hcfmusp.author.externalLIMA, Volney Soares:Oncoctr, Belo Horizonte, MG, Brazil
hcfmusp.author.externalADAMY JR., Ari:Hosp Santa Casa, Dept Urol, Curitiba, Parana, Brazil
hcfmusp.author.externalCAMPOS, Franz Santos de:INCA, Inst Nacl Canc, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalCARVALHAL, Gustavo Franco:Pontificia Univ Catolica Rio Grande do Sul, Dept Cirurgia, Porto Alegre, RS, Brazil; Pontificia Univ Catolica Rio Grande do Sul, Dept Urol, Porto Alegre, RS, Brazil
hcfmusp.author.externalCEZAR, Leandro Casemiro:Hosp Fed Cardoso Fontes, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalSADI, Marcus Vinicius:Univ Fed Sao Paulo, Sao Paulo, SP, Brazil
hcfmusp.author.externalREIS, Rodolfo Borges dos:Univ Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
hcfmusp.author.externalNOGUEIRA, Lucas:Univ Fed Minas Gerais, Hosp Clin, Dept Urol, Belo Horizonte, MG, Brazil
hcfmusp.citation.scopus5
hcfmusp.contributor.author-fmusphcDIOGO ASSED BASTOS
hcfmusp.contributor.author-fmusphcGEORGE BARBERIO COURA FILHO
hcfmusp.contributor.author-fmusphcMARCOS FRANCISCO DALL'OGLIO
hcfmusp.description.beginpage407
hcfmusp.description.endpage415
hcfmusp.description.issue3
hcfmusp.description.volume43
hcfmusp.origemWOS
hcfmusp.origem.pubmed28199075
hcfmusp.origem.scieloSCIELO:S1677-55382017000300407
hcfmusp.origem.scopus2-s2.0-85020167489
hcfmusp.origem.wosWOS:000403885400006
hcfmusp.publisher.cityRIO DE JANEIRO
hcfmusp.publisher.countryBRAZIL
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