Dysfunctional Family Environment in Children at High Risk for Bipolar Disorder

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMOREIRA, Carolina R. L.
dc.contributor.authorFERREIRA, Guilherme S.
dc.contributor.authorKLEINMAN, Ana
dc.contributor.authorNADER, Edmir
dc.contributor.authorGOMES, Bernardo C.
dc.contributor.authorTEIXEIRA, Ana Maria
dc.contributor.authorBUSATTO, Geraldo F.
dc.contributor.authorLAFER, Beny
dc.contributor.authorCAETANO, Sheila C.
dc.date.accessioned2013-10-11T21:25:24Z
dc.date.available2013-10-11T21:25:24Z
dc.date.issued2012
dc.description.abstractBackground: Children of parents with bipolar disorder (BD) are at heightened risk for developing psychiatric disorders. Environmental influences including family traits have been established as risk factors for psychopathology in children of affectively disordered parents. Our study evaluated the environment of families with at least one parent with BD compared to the environment of families with no history of axis I major psychiatric disorders (FNH). In addition, we compared the environment of BD families with offspring with BD or other psychiatric diagnoses (OPD), BD families with unaffected offspring (UO), and FNH. Methods: We used the Family Environment Scale to evaluate 47 BD families with at least one parent with a DSM-IV BD type I diagnosis and 30 FNH. BD and healthy parents were assessed through the Structured Clinical Interview for DSM-IV (SCID). Offspring of BD and healthy parents were ascertained through the K-SADS-PL interview. Results: Families with BD parents presented lower levels of family cohesion (p=0.001), intellectual-cultural orientation (p=0.005), active-recreational orientation (p=0.002) and organization (p[[Unsupported Character - ˂]]0.001), and higher levels of conflict (p[[Unsupported Character - ˂]]0.001) and control (p=0.04) compared to FNH. Secondary analysesrevealed significant difference between OBD, UO and FNH in cohesion (p=0.003), intellectual-cultural orientation (p=0,01), active-recreational orientation (p=0,007), conflict (p=0,001), control (p=0,01) and organization (p=0,001). BD families with affected offspring showed higher levels of control (p=0.02) compared to BD families with unaffected offspring. Conclusions: Families with BD parent show dysfunctional interaction among members. Moreover, the presence of BD or other psychiatric diagnosis in BD offspring is associated to higher levels of control.
dc.description.conferencedateMAY 03-05, 2012
dc.description.conferencelocalPhiladelphia - PA, EUA
dc.description.conferencename67th Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry
dc.description.indexMEDLINE
dc.identifier.citationBIOLOGICAL PSYCHIATRY, v.71, n.8, suppl.S, p.281S-282S, 2012
dc.identifier.issn0006-3223
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2974
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofBiological Psychiatry
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCIENCE INC
dc.subjectFamily environment
dc.subjectBipolar disorder
dc.subjectBipolar parents
dc.subjectHigh risk offspring
dc.subjectChild psychopathology
dc.subject.wosNeurosciences
dc.subject.wosPsychiatry
dc.titleDysfunctional Family Environment in Children at High Risk for Bipolar Disorder
dc.typeconferenceObject
dc.type.categorymeeting abstract
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.contributor.author-fmusphcCAROLINA ROGANTI LEITE MOREIRA
hcfmusp.contributor.author-fmusphcGUILHERME DOS SANTOS FERREIRA
hcfmusp.contributor.author-fmusphcANA KLEINMAN
hcfmusp.contributor.author-fmusphcEDMIR CAVALCANTI GURGEL PINI NADER
hcfmusp.contributor.author-fmusphcBERNARDO CARRAMAO GOMES
hcfmusp.contributor.author-fmusphcANA MARIA ARISTIMUNHO TEIXEIRA
hcfmusp.contributor.author-fmusphcGERALDO BUSATTO FILHO
hcfmusp.contributor.author-fmusphcBENY LAFER
hcfmusp.contributor.author-fmusphcSHEILA CAVALCANTE CAETANO
hcfmusp.description.beginpage281S
hcfmusp.description.endpage282S
hcfmusp.description.issue8
hcfmusp.description.issuesuppl S
hcfmusp.description.volume71
hcfmusp.origemWOS
hcfmusp.origem.wosWOS:000302466001202
hcfmusp.publisher.cityNEW YORK
hcfmusp.publisher.countryUSA
relation.isAuthorOfPublicationde5088fd-66ff-494c-ac00-c41eab77a94b
relation.isAuthorOfPublication94d33330-cc03-44ab-99bb-670cc2233928
relation.isAuthorOfPublicationd23effde-d9fc-436e-8231-c210a1904cfe
relation.isAuthorOfPublication4231eaf4-c1fc-4193-a1ea-042a6b6baaec
relation.isAuthorOfPublication826acf86-23a1-448c-afaf-94e6dc04c987
relation.isAuthorOfPublicationac32ed19-b81f-4616-8dfc-f13805b4d856
relation.isAuthorOfPublicationf6a44968-6960-4bd5-8722-8f605420e6bd
relation.isAuthorOfPublication717693ba-66ff-4dac-9ac5-86d07eafb715
relation.isAuthorOfPublication7224c93b-90cd-4870-bb1d-971d99439c17
relation.isAuthorOfPublication.latestForDiscovery717693ba-66ff-4dac-9ac5-86d07eafb715
Arquivos
Coleções
Comunicações em Eventos - FM/MPS
Comunicações em Eventos - HC/IPq
Comunicações em Eventos - LIM/21