Next-generation sequencing of circulating tumor DNA for metastatic non-small cell lung cancer: a discussion on its implementation in the Brazilian clinical practice

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorARAUJO, Luiz H
dc.contributor.authorFERREIRA, Carlos Gil
dc.contributor.authorBALDOTTO, Clarissa S.
dc.contributor.authorMATHIAS, Clarissa
dc.contributor.authorCASTRO JR., Gilberto
dc.contributor.authorCOUDRY, Renata
dc.date.accessioned2021-02-18T13:27:48Z
dc.date.available2021-02-18T13:27:48Z
dc.date.issued2020
dc.description.abstractThe objective of this review is to address the barriers limiting access to next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) for metastatic nonsquamous non-small cell lung cancer in Brazil and to propose its implementation in practice. A selected panel of lung cancer experts was provided with relevant prompts to address at a conference; a paper was then compiled on the topic. The authors propose specific and realistic recommendations for implementing access to ctDNA NGS. Further, the authors address all barriers and impediments mentioned within this review. There is a great need to increase ctDNA NGS for cancer care in Brazil. Adapting the current cancer testing framework is essential to expanding the use of this tool.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipAmericas Health Foundation (AHF)
dc.description.sponsorshipRocheRoche Holding
dc.identifier.citationFUTURE ONCOLOGY, v.17, n.2, p.205-214, 2020
dc.identifier.doi10.2217/fon-2020-0583
dc.identifier.eissn1744-8301
dc.identifier.issn1479-6694
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/39137
dc.language.isoeng
dc.publisherFUTURE MEDICINE LTDeng
dc.relation.ispartofFuture Oncology
dc.rightsopenAccesseng
dc.rights.holderCopyright FUTURE MEDICINE LTDeng
dc.subjectBrazileng
dc.subjectcirculating tumor DNAeng
dc.subjectmetastaticeng
dc.subjectnext-generation sequencingeng
dc.subjectNGSeng
dc.subjectnon-small cell lung cancereng
dc.subjectNSCLCeng
dc.subject.otherof-american-pathologistseng
dc.subject.othermutationseng
dc.subject.othervalidationeng
dc.subject.otherinhibitorseng
dc.subject.otherblockadeeng
dc.subject.otheroncologyeng
dc.subject.wosOncologyeng
dc.titleNext-generation sequencing of circulating tumor DNA for metastatic non-small cell lung cancer: a discussion on its implementation in the Brazilian clinical practiceeng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalARAUJO, Luiz H:Brazilian Natl Canc Inst, Rio De Janeiro, Brazil; COI Inst Res & Educ, Rio De Janeiro, Brazil
hcfmusp.author.externalFERREIRA, Carlos Gil:Oncoclin Inst Res & Educ, Rio De Janeiro, Brazil
hcfmusp.author.externalBALDOTTO, Clarissa S.:Inst DOr Res & Educ, Rio De Janeiro, Brazil
hcfmusp.author.externalMATHIAS, Clarissa:NOB Oncoclin, Salvador, BA, Brazil
hcfmusp.author.externalCOUDRY, Renata:United Hlth Grp Brazil, Sao Paulo, Brazil
hcfmusp.citation.scopus2
hcfmusp.contributor.author-fmusphcGILBERTO DE CASTRO JUNIOR
hcfmusp.description.beginpage205
hcfmusp.description.endpage214
hcfmusp.description.issue2
hcfmusp.description.volume17
hcfmusp.origemWOS
hcfmusp.origem.pubmed33052747
hcfmusp.origem.scopus2-s2.0-85099844817
hcfmusp.origem.wosWOS:000578231100001
hcfmusp.publisher.cityLONDONeng
hcfmusp.publisher.countryENGLANDeng
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