Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCOMERLATO, Juliana
dc.contributor.authorKOPS, Natalia Luiza
dc.contributor.authorBESSEL, Marina
dc.contributor.authorHORVATH, Jaqueline Driemeyer
dc.contributor.authorFERNANDES, Bruna Vieira
dc.contributor.authorVILLA, Luisa Lina
dc.contributor.authorSOUZA, Flavia Moreno Alves de
dc.contributor.authorPEREIRA, Gerson Fernando Mendes
dc.contributor.authorWENDLAND, Eliana Marcia
dc.date.accessioned2020-12-16T14:47:04Z
dc.date.available2020-12-16T14:47:04Z
dc.date.issued2020
dc.description.abstractBackground External genital lesions (EGL) are the most common sexually transmitted infections (STIs). We aimed to evaluate the prevalence, determinants and sex differences in EGL among young adults from Brazil. Methods Overall, 7694 participants (aged 16 to 25 years) underwent an interview, genital examination and sampling for HPV genotyping. Results The prevalence of EGL was 4.08% (234) and is more frequent in men (5.72%) than women (2.31%) (p < 0.001). Genital lesions were significantly associated with male sex, infection by high-risk and multiple HPV types, having more than two sexual partners in the last year, smoking status and the presence of other STI. While alcohol use was associated with a higher prevalence of EGL in women, same-sex sexual relationship increase the prevalence in men. In the EGL group, 67.79% (p = 0.032) were positive for HPV infection and the types HPV6 and HPV11 were the most prevalent ones. Conclusion The prevalence of EGL in young adults was consistently high, and most cases were associated with genital HPV infection and STIs. Although men have a higher prevalence, both sexes share most genital lesion determinants. The promotion of sexual education and vaccination especially focus in young men, who are usually outside the targets of primary health care programmes, can prevent EGL in Brazilian young adults.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipHospital Moinhos de Vento through the Program for Supporting the Institutional Development of the Public Health System (PROADI-SUS)
dc.description.sponsorshipBrazilian Ministry of Health
dc.identifier.citationBMC INFECTIOUS DISEASES, v.20, n.1, article ID 683, 8p, 2020
dc.identifier.doi10.1186/s12879-020-05376-x
dc.identifier.eissn1471-2334
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/38323
dc.language.isoeng
dc.publisherBMCeng
dc.relation.ispartofBMC Infectious Diseases
dc.rightsopenAccesseng
dc.rights.holderCopyright BMCeng
dc.subjectHuman papillomaviruseng
dc.subjectGenital wartseng
dc.subjectHPVeng
dc.subjectEpidemiologyeng
dc.subjectPrevalence in young adultseng
dc.subject.otherhuman-papillomaviruseng
dc.subject.otherinfectioneng
dc.subject.othermeneng
dc.subject.othergenotypeeng
dc.subject.otherburdeneng
dc.subject.otherwartseng
dc.subject.otherdiseaseeng
dc.subject.otherwomeneng
dc.subject.wosInfectious Diseaseseng
dc.titleSex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazileng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalCOMERLATO, Juliana:Hosp Moinhos Vento, PROADI SUS, Ramiro Barcelos 910, BR-90035004 Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Hlth Sci, Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Pediat, Porto Alegre, RS, Brazil
hcfmusp.author.externalKOPS, Natalia Luiza:Hosp Moinhos de Vento, Porto Alegre, RS, Brazil
hcfmusp.author.externalBESSEL, Marina:Hosp Moinhos de Vento, Porto Alegre, RS, Brazil
hcfmusp.author.externalHORVATH, Jaqueline Driemeyer:Hosp Moinhos de Vento, Porto Alegre, RS, Brazil
hcfmusp.author.externalFERNANDES, Bruna Vieira:Hosp Moinhos Vento, PROADI SUS, Ramiro Barcelos 910, BR-90035004 Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Hlth Sci, Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Pediat, Porto Alegre, RS, Brazil
hcfmusp.author.externalSOUZA, Flavia Moreno Alves de:Minist Hlth, Dept Chron Condit & Sexually Transmitted Infect, Brasilia, DF, Brazil
hcfmusp.author.externalPEREIRA, Gerson Fernando Mendes:Minist Hlth, Dept Chron Condit & Sexually Transmitted Infect, Brasilia, DF, Brazil
hcfmusp.author.externalWENDLAND, Eliana Marcia:Hosp Moinhos Vento, PROADI SUS, Ramiro Barcelos 910, BR-90035004 Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Hlth Sci, Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre, Grad Program Pediat, Porto Alegre, RS, Brazil
hcfmusp.citation.scopus8
hcfmusp.contributor.author-fmusphcLUISA LINA VILLA
hcfmusp.description.articlenumber683
hcfmusp.description.issue1
hcfmusp.description.volume20
hcfmusp.origemWOS
hcfmusp.origem.pubmed32948142
hcfmusp.origem.scopus2-s2.0-85091324292
hcfmusp.origem.wosWOS:000574618800005
hcfmusp.publisher.cityLONDONeng
hcfmusp.publisher.countryENGLANDeng
hcfmusp.relation.reference[Anonymous], PROT CLIN DIR TER ATeng
hcfmusp.relation.reference[Anonymous], 2017, DOIS MED TRAT HPV SAeng
hcfmusp.relation.referenceBellaminutti S, 2014, J MED VIROL, V86, P1920, DOI 10.1002/jmv.24041eng
hcfmusp.relation.referenceBhatia N, 2013, J CUTAN MED SURG, V17, pS47, DOI 10.2310/7750.2013.13072eng
hcfmusp.relation.referenceCampbell CMP, 2016, VIROLOGY, V497, P314, DOI 10.1016/j.virol.2016.08.002eng
hcfmusp.relation.referenceda Silva RJC, 2017, BRAZ J INFECT DIS, V21, P376, DOI 10.1016/j.bjid.2017.03.004eng
hcfmusp.relation.referenceChesson HW, 2014, SEX TRANSM DIS, V41, P660, DOI 10.1097/OLQ.0000000000000193eng
hcfmusp.relation.referenceCremin S, 2012, HUM VACC IMMUNOTHER, V8, P916, DOI 10.4161/hv.20122eng
hcfmusp.relation.referenceCrosbie EJ, 2013, LANCET, V382, P889, DOI 10.1016/S0140-6736(13)60022-7eng
hcfmusp.relation.referenceDahlstrom KR, 2018, PHARMACOECONOMICS, V36, P1355, DOI 10.1007/s40273-018-0691-9eng
hcfmusp.relation.referencede Lima S, 2008, CAD SAUDE PUBLICA, V24, P1910, DOI 10.1590/S0102-311X2008000800019eng
hcfmusp.relation.referenceDidelot-Rousseau MN, 2006, BRIT J CANCER, V95, P355, DOI 10.1038/sj.bjc.6603252eng
hcfmusp.relation.referenceForman D, 2012, VACCINE, V30, pF12, DOI 10.1016/j.vaccine.2012.07.055eng
hcfmusp.relation.referenceGarcia PJ, 2019, INT J STD AIDS, V30, P264, DOI 10.1177/0956462418796088eng
hcfmusp.relation.referenceGianino MM, 2013, BMC INFECT DIS, V13, DOI 10.1186/1471-2334-13-470eng
hcfmusp.relation.referenceGuerra FM, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-009914eng
hcfmusp.relation.referenceHasanzadeh M, 2019, J CELL BIOCHEM, V120, P12870, DOI 10.1002/jcb.28557eng
hcfmusp.relation.referenceHernandez-Suarez G, 2013, INT J STD AIDS, V24, P567, DOI 10.1177/0956462412474538eng
hcfmusp.relation.referenceIngles DJ, 2015, J INFECT DIS, V211, P1060, DOI 10.1093/infdis/jiu587eng
hcfmusp.relation.referenceKhopkar US, 2018, VIRAL IMMUNOL, V31, P346, DOI 10.1089/vim.2017.0157eng
hcfmusp.relation.referenceKim HS, 2016, J GYNECOL ONCOL, V27, DOI 10.3802/jgo.2016.27.e49eng
hcfmusp.relation.referenceLazcano-Ponce E, 2018, SALUD PUBLICA MEXICO, V60, P633, DOI 10.21149/8461eng
hcfmusp.relation.referenceLeslie SW, 2020, STATPEARLS INTERNETeng
hcfmusp.relation.referenceLuo Zhao-Yun, 2015, Asian Pac J Cancer Prev, V16, P5675eng
hcfmusp.relation.referenceMin KJ, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0072142eng
hcfmusp.relation.referenceMohammed H, 2018, SEX TRANSM INFECT, V94, P553, DOI 10.1136/sextrans-2017-053273eng
hcfmusp.relation.referenceMuhr LSA, 2015, VIROLOGY, V485, P283, DOI 10.1016/j.virol.2015.07.023eng
hcfmusp.relation.referenceNilyanimit P, 2018, INTERVIROLOGY, V61, P223, DOI 10.1159/000497351eng
hcfmusp.relation.referenceOnyekwuluje JM, 2012, CLIN LAB, V58, P61eng
hcfmusp.relation.referenceostensson E, 2015, PLOS ONE, V10eng
hcfmusp.relation.referenceOzaydin-Yavuz G, 2019, POSTEP DERM ALERGOL, V36, P76, DOI 10.5114/ada.2019.82915eng
hcfmusp.relation.referencePatel H, 2013, BMC INFECT DIS, V13, DOI 10.1186/1471-2334-13-39eng
hcfmusp.relation.referenceRodrigues LLS, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0215001eng
hcfmusp.relation.referenceSchabath MB, 2015, SEX TRANSM INFECT, V91, P61, DOI 10.1136/sextrans-2013-051422eng
hcfmusp.relation.referenceSudenga SL, 2017, INT J CANCER, V140, P337, DOI 10.1002/ijc.30452eng
hcfmusp.relation.referenceVelazquez-Hernandez Nadia, 2019, J Clin Med Res, V11, P196, DOI 10.14740/jocmr3739eng
hcfmusp.relation.referenceWendland E. M., 2020, SCI REPORTS, V10, P1, DOI 10.1038/s41598-020-61582-2.eng
hcfmusp.relation.referenceWendland EM, 2018, MEDICINE, V97, DOI 10.1097/MD.0000000000011758eng
hcfmusp.relation.referenceZhu CS, 2019, BMJ OPEN, V9, DOI 10.1136/bmjopen-2018-023897eng
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