Impact of the Severity of End-Stage Liver Disease in Cardiac Remodeling

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSILVESTRE, O. M.
dc.contributor.authorBACAL, F.
dc.contributor.authorFARIAS, A. Q.
dc.contributor.authorANDRADE, J. L.
dc.contributor.authorFURTADO, M.
dc.contributor.authorPUGLIESE, V.
dc.contributor.authorANDRAUS, W.
dc.contributor.authorRAMOS, D. S.
dc.contributor.authorBELLETI, E.
dc.contributor.authorALBUQUERQUE, L. A. C.
dc.contributor.authorCARRILHO, F. J.
dc.date.accessioned2013-10-11T21:19:47Z
dc.date.available2013-10-11T21:19:47Z
dc.date.issued2012
dc.description.abstractPurpose: The impact of end-stage liver disease (ESLD) in cardiac remodeling of patients with cirrhosis is unknown. Our aim was to correlate the severity of ESLD with morphologic and functional heart changes. Methods and Materials: 184 patients underwent a protocol providing data on the severity of ESLD and undergoing echocardiography to assess the diameters of the left atrium and right ventricle; the systolic and diastolic diameters of the left ventricle, interventricular septum, and posterior wall of the left ventricle; systolic pulmonary artery pressure; ejection fraction; and diastolic function. Severity of ESLD was assessed by the Model for End-Stage Liver Disease (MELD) score. Results: Left-atrial diameter (r=0.323; IC 95% 0.190-0.455; p<0.001), left-ventricular diastolic diameter (r=0.177; IC 95% 0.033-0.320; p=0.01) and systolic pulmonary artery pressure (r=0.185; IC 95% 0.036-0.335; p=0.02) significantly correlated with MELD score. Patients with MELD >16 had significantly higher left-atrial diameter and systolic pulmonary artery pressure, compared with patients with MELD scores <16 points. Conclusions: Changes in cardiac structure and function correlate with the severity of ESLD.
dc.description.conferencedateAPR 17-21, 2012
dc.description.conferencelocalPrague, CZECH REPUBLIC
dc.description.conferencename32nd Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation/Meeting of the ISHLT Academy - Core Competencies in Mechanical Circulatory Support
dc.description.indexMEDLINE
dc.identifier.citationJOURNAL OF HEART AND LUNG TRANSPLANTATION, v.31, n.4, suppl.S, p.S152-S152, 2012
dc.identifier.issn1053-2498
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2884
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofJournal of Heart and Lung Transplantation
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCIENCE INC
dc.subject.wosCardiac & Cardiovascular Systems
dc.subject.wosRespiratory System
dc.subject.wosTransplantation
dc.titleImpact of the Severity of End-Stage Liver Disease in Cardiac Remodeling
dc.typeconferenceObject
dc.type.categorymeeting abstract
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalBELLETI, E.:Univ Sao Paulo, Sch Med, Sao Paulo, Brazil
hcfmusp.contributor.author-fmusphcODILSON MARCOS SILVESTRE
hcfmusp.contributor.author-fmusphcFERNANDO BACAL
hcfmusp.contributor.author-fmusphcALBERTO QUEIROZ FARIAS
hcfmusp.contributor.author-fmusphcJOSE LAZARO DE ANDRADE
hcfmusp.contributor.author-fmusphcMEIVE SANTOS FURTADO
hcfmusp.contributor.author-fmusphcVINCENZO PUGLIESE
hcfmusp.contributor.author-fmusphcWELLINGTON ANDRAUS
hcfmusp.contributor.author-fmusphcDANUSA DE SOUZA RAMOS
hcfmusp.contributor.author-fmusphcLUIZ AUGUSTO CARNEIRO D ALBUQUERQUE
hcfmusp.contributor.author-fmusphcFLAIR JOSE CARRILHO
hcfmusp.description.beginpageS152
hcfmusp.description.endpageS152
hcfmusp.description.issue4
hcfmusp.description.issuesuppl S
hcfmusp.description.volume31
hcfmusp.origemWOS
hcfmusp.origem.wosWOS:000302207900429
hcfmusp.publisher.cityNEW YORK
hcfmusp.publisher.countryUSA
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