Six- minute walk test (6MWT) in children and teenages with chronic kidney disease: tolerance, reproducibility and comparison with normal reference values
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conferenceObject
Data de publicação
2013
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SPRINGER
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Citação
PEDIATRIC NEPHROLOGY, v.28, n.8, p.1365-1365, 2013
Resumo
Objective: To evaluate exercise tolerance using the six-minute walk test (6MWT) in children and adolescents with stage 5 chronic kidney disease (CKD, to assess the reproducibility of the 6MWT and compare the performance of these children with reference values. Methods: Children and adolescents aged 6 to 16 years with stage 5 CKD were evaluated prospectively using 6MWT, according to the American Thoracic Society methodology. Measurement of Heart rate (HR), respiratory rate (RR), pulse oxygen saturation (SpO2), blood pressure (BP) and dyspnea scale (Borg) at rest (pre) and posttest (post) was performed. The test with the larger walked distance was considered for analysis. Reproducibility was evaluated by t-test and the Bland-Altman methods. Brazilian population reference values were used for comparison with normal children. Results: We studied 38 children and adolescents (14F:24M), 4 on peritoneal dialysis, 12 hemodialysis and 22 post renal transplantation with a mean age of 11.3 ± 2.9 years, mean weight of 32.3 ± 11.7 kg, mean height of 131 ± 17cm and mean BMI of 18.3 ± 3.1 kg/m2. There were no adverse events observed during or after the tests. The 6MWT was found to be reproducible, second walk walked distances were greater than first walk ones (p <0.001). Children with CKD performed significantly poorer (548.9 ± 71.4 m) than reference values of children with similar height (576.46 ±39.76 m) (p <0.001). HR, SpO2, systolic BP (pre), diastolic BP were significantly higherin children with CKD. Conclusion: The 6MWT proved to be safe, reproducible and well tolerated. A learning effect was observed between the first and second test. CKD patients performed significantly poorer than reference values.