Self-expandable metallic stent-induced esophagorespiratory fistulas in patients with advanced esophageal cancer

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorJOSINO, Iatagan R.
dc.contributor.authorMARTINS, Bruno C.
dc.contributor.authorMACHADO, Andressa A.
dc.contributor.authorLIMA, Gustavo R. de A.
dc.contributor.authorCORDERO, Martin A. C.
dc.contributor.authorPOMBO, Amanda A. M.
dc.contributor.authorSALLUM, Rubens A. A.
dc.contributor.authorJR, Ulysses Ribeiro
dc.contributor.authorBARON, Todd H.
dc.contributor.authorMALUF-FILHO, Fauze
dc.date.accessioned2024-04-05T19:31:42Z
dc.date.available2024-04-05T19:31:42Z
dc.date.issued2023
dc.description.abstractBackground/Aims: Self-expandable metallic stents (SEMSs) are widely adopted for the palliation of dysphagia in patients with malignant esophageal strictures. An important adverse event is the development of SEMS-induced esophagorespiratory fistulas (SEMSERFs). This study aimed to assess the risk factors related to the development of SEMS-ERF after SEMS placement in patients with esophageal cancer. Methods: This retrospective study was performed at the Instituto do Cancer do Estado de Sao Paulo. All patients with malignant esophageal strictures who underwent esophageal SEMS placement between 2009 and 2019 were included in the study. Results: Of the 335 patients, 37 (11.0%) developed SEMS-ERF, with a median time of 129 days after SEMS placement. Stent flare of 28 mm (hazard ratio [HR], 2.05; 95% confidence interval [CI], 1.15-5.51; p=0.02) and post-stent chemotherapy (HR, 2.0; 95% CI, 1.01- 4.00; p=0.05) were associated with an increased risk of developing SEMS-ERF, while lower-third tumors were a protective factor (HR, 0.5; 95% CI, 0.26-0.85; p=0.01). No difference was observed in overall survival. Conclusions: The incidence of SEMS-ERFs was 11%, with a median time of 129 days after SEMS placement. Post-stent chemotherapy and a 28 mm stent flare were associated with a higher risk of SEMS-ERF.eng
dc.description.indexPubMed
dc.description.indexScopus
dc.description.indexDimensions
dc.description.indexWoS
dc.identifier.citationCLINICAL ENDOSCOPY, v.56, n.6, p.761-768, 2023
dc.identifier.doi10.5946/ce.2022.297
dc.identifier.eissn2234-2443
dc.identifier.issn2234-2400
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/58883
dc.language.isoeng
dc.publisherKOREAN SOC GASTROINTESTINAL ENDOSCOPYeng
dc.relation.ispartofClinical Endoscopy
dc.rightsopenAccesseng
dc.rights.holderCopyright KOREAN SOC GASTROINTESTINAL ENDOSCOPYeng
dc.subjectEsophageal fistulaeng
dc.subjectEsophageal neoplasmseng
dc.subjectSelf-expandable metallic stentseng
dc.subject.othermalignant dysphagiaeng
dc.subject.otherprior radiationeng
dc.subject.otheradverse eventseng
dc.subject.othercomplicationseng
dc.subject.otherplacementeng
dc.subject.otherchemotherapyeng
dc.subject.otherpalliationeng
dc.subject.othersurvivaleng
dc.subject.otherradiotherapyeng
dc.subject.otherexperienceeng
dc.subject.wosGastroenterology & Hepatologyeng
dc.titleSelf-expandable metallic stent-induced esophagorespiratory fistulas in patients with advanced esophageal cancereng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalLIMA, Gustavo R. de A.:Univ Sao Paulo, Dept Gastroenterol, Inst Canc Estado Sao Paulo, Hosp Clin,Fac Med, Sao Paulo, Brazil
hcfmusp.author.externalBARON, Todd H.:Univ N Carolina, Div Gastroenterol & Hepatol, Chapel Hill, NC USA
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcIATAGAN ROCHA JOSINO
hcfmusp.contributor.author-fmusphcBRUNO DA COSTA MARTINS
hcfmusp.contributor.author-fmusphcANDRESSA ABNADER MACHADO
hcfmusp.contributor.author-fmusphcMARTIN ANDRES CORONEL CORDERO
hcfmusp.contributor.author-fmusphcAMANDA AQUINO DE MIRANDA POMBO
hcfmusp.contributor.author-fmusphcRUBENS ANTONIO AISSAR SALLUM
hcfmusp.contributor.author-fmusphcULYSSES RIBEIRO JUNIOR
hcfmusp.contributor.author-fmusphcFAUZE MALUF FILHO
hcfmusp.description.beginpage761
hcfmusp.description.endpage768
hcfmusp.description.issue6
hcfmusp.description.volume56
hcfmusp.origemWOS
hcfmusp.origem.dimensionspub.1162712829
hcfmusp.origem.pubmed37491991
hcfmusp.origem.scopus2-s2.0-85179469766
hcfmusp.origem.wosWOS:001110340700014
hcfmusp.publisher.citySEOULeng
hcfmusp.publisher.countrySOUTH KOREAeng
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hcfmusp.scopus.lastupdate2024-05-17
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